Abstract:
:The pacemaker syndrome refers to symptoms and signs in the pacemaker patient caused by inadequate timing of atrial and ventricular contractions. The lack of normal atrioventricular synchrony may result in decreased cardiac output and venous "cannon A waves." A sudden increase in atrial pressure at the onset of asynchrony may elicit a systemic hypotensive reflex response. A wide range of symptoms can be observed. The pacemaker syndrome is encountered in a significant number of patients with ventricular (VVI) pacemakers, mostly when 1:1 retrograde ventriculoatrial conduction is present. The risk of occurrence of the pacemaker syndrome is minimized if pacemaker systems are used which restore or maintain the normal atrioventricular contraction sequence. Hence, in sinus node disease, atrial stimulation with or without ventricular stimulation should be employed, while in high-grade atrioventricular block dual-chamber pacing is recommended. The pacemaker syndrome is not restricted to the VVI stimulation mode. It can be seen, though rarely, in atrial and dual-chamber pacing, and an awareness of these new causes is necessary. An established pacemaker syndrome can often be counteracted by adjusting the pulse generator function.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Schüller H,Brandt Jdoi
10.1002/clc.4960140410subject
Has Abstractpub_date
1991-04-01 00:00:00pages
336-40issue
4eissn
0160-9289issn
1932-8737journal_volume
14pub_type
杂志文章,评审abstract:BACKGROUND:Atrial fibrillation (AF), a disease of the elderly, occasionally occurs at younger age. Pathophysiology of AF in younger patients is diverse, including channelopathies and cardiomyopathies. Data on the significance and complications of AF in young patients are scarce. HYPOTHESIS:Atrial fibrillation is the f...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22516
更新日期:2016-04-01 00:00:00
abstract::In addition to the role of the electrophysiological substrate, paroxysmal atrial fibrillation depends on the modulation of the atrial tissues by the autonomic nervous system. Experimentally, models of atrial fibrillation can be based on either adrenergic or vagal stimulations that provoke the arrhythmia by disturbing ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960130311
更新日期:1990-03-01 00:00:00
abstract::Balancing the benefits, risks, and cost of thrombolytic treatment is a complex issue which depends considerably upon the variable threat of the thrombus to organ physiology and patient survival. For example, after deep vein thrombosis (DVT), the major risk is long-term disability due to the postphlebitic syndrome, whi...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1990-04-01 00:00:00
abstract::Individuals age >65 years represent the fastest-growing subpopulation in the United States. Although these individuals with the highest cardiovascular risk profile would be anticipated to be the most aggressively treated, paradoxically, treatment and baseline risk are inversely related. Presumably, the elderly populat...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22338
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The extracellular matrix tissue of the myocardium importantly contributes to left ventricular (LV) performance. Inherited connective tissue disorders related to the FBN1 gene could involve cardiac interstitium resulting in functional abnormalities. HYPOTHESIS:To disclose a primary involvement of myocardium,...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960250905
更新日期:2002-09-01 00:00:00
abstract::Women's health and well-being are shaped by a combination of healthcare policies that impact the type of health insurance coverage they benefit from, as well as access to preventive, screening, and treatment services. Furthermore, more distal policies, such as those that pertain to housing, education, and employment, ...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.22896
更新日期:2018-02-01 00:00:00
abstract::In patients with malignant ventricular arrhythmias, antiarrhythmic therapy is known to carry a substantial risk of proarrhythmia. This risk is usually considered to be low when supraventricular arrhythmias or benign ventricular arrhythmias are considered. We were able to collect data on four patients without a history...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960170410
更新日期:1994-04-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:The aim of this study was to define the prevalence of previously undetected coronary heart disease among asymptomatic males, aged 30-65 years, by means of resting and exercise electrocardiography in conjunction with an analysis of conventional and exertional coronary risk factors. METHODS:Bet...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960190405
更新日期:1996-04-01 00:00:00
abstract::The purpose of this paper is to review the history of the clinico-pathologic investigations performed at the University of Padua on an old morbid entity ("parchment heart"), which, in the 1960s, led to the clinical description of the disease, in the 1980s to the revival of the scientific interest, and in the mid 1990s...
journal_title:Clinical cardiology
pub_type: 历史文章,杂志文章
doi:10.1002/clc.4960200406
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:Advanced age remains one of the principal determinants of mortality in patients with acute myocardial infarction (AMI). HYPOTHESIS:The aim of this study was to determine the in-hospital outcome of elderly (> 75 years) patients with AMI who were admitted to hospitals participating in the national MITRA (Maxi...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960231109
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Management of acute coronary syndrome (ACS) patients with nonobstructive epicardial coronary artery disease (CAD) remains poorly understood. HYPOTHESIS:Acute coronary syndrome patients with nonobstructive CAD are less likely to receive effective cardiac medications upon discharge from the hospital. METHODS...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20701
更新日期:2010-01-01 00:00:00
abstract::Angina pectoris usually occurs in patients with significant coronary artery disease during periods of increased coronary demand such as increased heart rate. Bradycardia is a rare and unusal cause of angina pectoris that should be considered during the evaluation of patients with agnia. This paper reports three cases ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960230619
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:The prognostic ability of cardiac troponin I (TnI) has been demonstrated in general populations and among cardiovascular disease patients, but it has not been evaluated in cancer patients. HYPOTHESIS:This study assumes to have the prognostic ability of cardiac troponin in cancer patients visiting the emerge...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23486
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Aortic valve disease is an important and frequent clinical problem with a mortality rate as high as 50-80% in a 5-year natural history of patients with severe aortic valve disease. Biological or mechanical prosthesis implantation is the only way to improve prognosis. HYPOTHESIS:The aim of our study was to a...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960201010
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to examine the influence of atrial fibrillation (AF) on the immediate and long-term outcome of patients undergoing balloon mitral valvotomy (BMV). HYPOTHESIS:Patients with atrial fibrillation fair poorly after balloon mitral valvotomy. METHODS:There were a total of 818 consecu...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22068
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Until now there were no clinical studies or systematic reviews to investigate the impact of timing on efficacy and safety of intracoronary bone marrow stem cell (BMSC) transfer in patients with acute myocardial infarction (AMI). HYPOTHESIS:Timing of BMSC administration might play an important role in the th...
journal_title:Clinical cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1002/clc.20575
更新日期:2009-08-01 00:00:00
abstract::Although optimal pharmacological therapy for heart failure with reduced ejection fraction (HFrEF) is carefully scripted by treatment guidelines, many eligible patients are not treated with guideline-directed medical therapy (GDMT) in clinical practice. We designed a strategy for remote optimization of GDMT on a popula...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23291
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Obesity can lead to increased oxidative stress which is one of the proposed mechanisms in the etiopathogenesis of takotsubo cardiomyopathy (TCM). HYPOTHESIS:The presence of obesity adversely impacts clinical outcomes in TCM patients. METHODS:We queried the Nationwide Inpatient Sample database (2010-2014) t...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.22999
更新日期:2018-08-01 00:00:00
abstract::The importance of treatment in systemic hypertension and cardiovascular morbidity and mortality has been established. Although systemic hypertension is the most important factor in the pathogenesis of left ventricular hypertrophy, other factors such as catecholamines and renin-angiotensin system may be involved. Incre...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960150104
更新日期:1992-01-01 00:00:00
abstract::High dose-dobutamine (DOB) has been previously used as a pharmacological stress test to evaluate wall motion abnormalities. As a result, recent stress echocardiography with low-dose DOB has been reported to be valuable for investigating stunned myocardium after thrombolysis. However, echocardiography requires an opera...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960160604
更新日期:1993-06-01 00:00:00
abstract::The Randomized Endo-vein Graft Prospective (REGROUP) trial (ClinicalTrials.gov NCT01850082) is a randomized, intent-to-treat, 2-arm, parallel-design, multicenter study funded by the Cooperative Studies Program (CSP No. 588) of the US Department of Veterans Affairs. Cardiac surgeons at 16 Veterans Affairs (VA) medical ...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.22267
更新日期:2014-06-01 00:00:00
abstract::Based on the foregoing data it is not unreasonable to hypothesize that restoration of flow in the infarct-related artery at a later date might decrease mortality. If that is the case, then a strong argument can be made for coronary angiography in patients surviving acute myocardial infarction. Of course, the ideal way...
journal_title:Clinical cardiology
pub_type: 社论
doi:10.1002/clc.4960170405
更新日期:1994-04-01 00:00:00
abstract::Evidence is now accumulating which strongly suggests that prognosis of patients with painless myocardial ischemia determined either by ambulatory ECG monitoring or exercise testing may be no different than the prognosis of patients who have overt clinical manifestations of myocardial ischemia associated with transient...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960111202
更新日期:1988-12-01 00:00:00
abstract::Diffuse pulmonary hemorrhage has rarely been reported as a complication of thrombolytic therapy. Recently, two patients who developed this complication were observed at our institution. This diagnosis should be considered in any post-thrombolytic patient with respiratory distress, diffuse pulmonary infiltrates, and an...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960200321
更新日期:1997-03-01 00:00:00
abstract::We report a patient who presented with new onset atrial fibrillation in the setting of inferior ST-segment elevation myocardial infarction (STEMI). Cardiac catheterization revealed proximal occlusion of the left circumflex artery. Balloon angioplasty and stenting restored flow to a large left atrial branch, with promp...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20573
更新日期:2010-12-01 00:00:00
abstract::Sinus tachycardia is the most common rhythm disturbance encountered in clinical practice. Primary sinus tachycardia without an underlying secondary cause, despite often being associated with troublesome symptoms, is often neglected leading to multiple consultations and frustration on part of both the practitioner and ...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960280603
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) reduce perioperative cardiac events in high-risk patients undergoing cardiovascular surgery. However, there is paucity of data on the role of statins in patients undergoing intermediate-risk noncardiac, nonvascular surgery (NCNVS). HYPOTHESIS:S...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22135
更新日期:2013-08-01 00:00:00
abstract::Left ventricular systolic dysfunction (LVSD) and clinical heart failure are common complications of acute myocardial infarction (AMI) and result in substantially increased mortality and morbidity. Evidence-based cardiovascular protective therapies, including angiotensin-converting enzyme inhibitors, beta blockers, ant...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960290103
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:One-third of patients who receive cardiac resynchronization therapy (CRT) are classified as nonresponders. Characteristics of responders to CRT have been studied in multiple clinical trials. HYPOTHESIS:Independent predictors of CRT response may be identified by studying a series of patients in routine clini...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22043
更新日期:2012-12-01 00:00:00
abstract::A total of 140 consecutive patients with acute Q-wave myocardial infarction was evaluated to assess the relationship between different electrocardiographic patterns of evolution and the incidence of recurrent ischemia within 10 days of infarction. Patients were allocated to three groups according to the electrocardiog...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960181205
更新日期:1995-12-01 00:00:00