A casual spontaneous mutation as possible cause of the familial form of arrhythmogenic right ventricular cardiomyopathy (arrhythmogenic right ventricular dysplasia).

Abstract:

:In a family affected by arrhythmogenic right ventricular cardiomyopathy (ARVC) the familial occurrence was investigated. All 14 members of two generations were investigated carefully, and only 2 (father and one son) members were affected. Both subjects had a massive form of the disease with relevant ventricular arrhythmias. Apart from the limitations of having investigated few subjects, this behavior suggests a genetic mutation appearing in the father and transmitted via an autosomal dominant trait.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Canciani B,Nava A,Toso V,Martini B,Thiene G

doi

10.1002/clc.4960150314

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

217-9

issue

3

eissn

0160-9289

issn

1932-8737

journal_volume

15

pub_type

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