Association between anxiety and clinical outcomes in Chinese patients with myocardial infarction in the absence of obstructive coronary artery disease.

Abstract:

BACKGROUND:Myocardial infarction in the absence of obstructive coronary artery disease (MINOCA) accounts for approximately 5% - 6% of acute myocardial infarction (AMI) patients. Anxiety symptoms are common in patients with coronary artery disease (CAD), and are associated with a poor prognosis. However, the association between anxiety and MINOCA outcomes is less clear. HYPOTHESIS:Anxiety will be associated with clinical outcomes in patients with MINOCA. METHODS AND RESULTS:Between November 2014 and December 2016, 620 hospitalized patients with MINOCA were recruited from a single center. Within 7 days of coronary angiography, anxiety was assessed using the Zung Self-Rating Anxiety Scale. The primary endpoint was all-cause mortality; secondary endpoint was any major adverse cardiovascular event (MACE). After 3 years, 87 deaths and 151 MACE had occurred. Kaplan-Meier curves indicated the unadjusted rates of all-cause mortality (log-rank P = .045) and MACE (log-rank P = .023) were significantly higher in the anxiety group compared with the control group of patients without anxiety. Multivariate Cox regression analysis showed that clinically significant anxiety was an independent prognostic factor for all-cause mortality as well as MACE (hazard ratio [HR] = 1.547; 95% confidence interval [CI], 1.006-2.380; P = .047; HR = 1.460; 95% CI, 1.049-2.031; P = .025; respectively). CONCLUSIONS:Anxiety is significantly and independently associated with an increased risk of all-cause mortality and MACE in patients with MINOCA.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

He CJ,Zhu CY,Han B,Hu HZ,Wang SJ,Zhai CL,Hu HL

doi

10.1002/clc.23386

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

659-665

issue

7

eissn

0160-9289

issn

1932-8737

journal_volume

43

pub_type

杂志文章
  • New antithrombotics for secondary prevention of acute coronary syndrome.

    abstract::Patients with acute coronary syndrome (ACS) usually receive acetylsalicylic acid plus an adenosine diphosphate (ADP) receptor inhibitor to reduce the long-term risk of recurrent events. However, patients receiving standard antiplatelet prophylaxis still face a substantial risk of recurrent events. Strategies involving...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.22233

    authors: Goto S,Tomita A

    更新日期:2014-03-01 00:00:00

  • Reduced cardiac function is associated with cardiac injury and mortality risk in hospitalized COVID-19 Patients.

    abstract:BACKGROUND:Cardiac injury is common in COVID-19 patients and is associated with increased mortality. However, it remains unclear if reduced cardiac function is associated with cardiac injury, and additionally if mortality risk is increased among those with reduced cardiac function in COVID-19 patients. HYPOTHESIS:The ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23479

    authors: Chen LQ,Burdowski J,Marfatia R,Weber J,Gliganic K,Diaz N,Ramjattan N,Zheng H,Mihalatos D,Wang L,Barasch E,Leung A,Gopal A,Craft J,Ren X,Stergiopoulos K,Jeremias A,Petrossian G,Robinson N,Levine J,Shlofmitz RA,Gu

    更新日期:2020-12-01 00:00:00

  • The measurement of lipids currently and 9 years ago--which is more associated with carotid intima-media thickness?

    abstract:BACKGROUND:Massive evidence supports that increase of lipids bring more risk of atherosclerosis. However, it is not clear if lipids measured a long time ago bear more risk than the current measurement. HYPOTHESIS:Lipids measured currently is more associated with carotid atherosclerosis than lipids measured long time a...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22015

    authors: Huang Y,Yu X,Millican D,Wu L,Shi P,Lu M,Wu Y

    更新日期:2012-08-01 00:00:00

  • In-hospital mortality of elderly patients with acute myocardial infarction: data from the MITRA (Maximal Individual Therapy in Acute Myocardial Infarction) registry.

    abstract:BACKGROUND:Advanced age remains one of the principal determinants of mortality in patients with acute myocardial infarction (AMI). HYPOTHESIS:The aim of this study was to determine the in-hospital outcome of elderly (> 75 years) patients with AMI who were admitted to hospitals participating in the national MITRA (Maxi...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960231109

    authors: Haase KK,Schiele R,Wagner S,Fischer F,Burczyk U,Zahn R,Schuster S,Senges J

    更新日期:2000-11-01 00:00:00

  • Carotid artery stenting in clinical practice: does sex matter? Results from the carotid artery stenting registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK).

    abstract:BACKGROUND:Carotid artery stenting (CAS) is increasingly used for treatment of severe carotid artery stenosis, but only few procedural risk factors for complications of CAS are clearly defined yet. A possible impact of the patient's gender on the outcome of patients undergoing CAS has not been investigated properly and...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/clc.21015

    authors: Werner N,Zeymer U,Mark B,Hochadel M,Hauptmann KE,Jung J,Hoffmann E,Elsässer A,Fürste T,Leschke M,Mudra H,Zahn R,Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK).

    更新日期:2012-02-01 00:00:00

  • Rate-responsive pacing and atrial high rate episodes in cardiac resynchronization therapy patients: Is low heart rate the key?

    abstract:BACKGROUND:The role of atrial rate-responsive (RR) pacing in cardiac resynchronization therapy (CRT) is unclear due to the favorable effect of rate lowering in systolic heart failure. Atrial high rate episodes (AHREs) in CRT recipients are particularly worrisome since they cause loss of CRT, beyond representing a strok...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23227

    authors: Biffi M,D'Onofrio A,Pignalberi C,Pisanò EC,Iacopino S,Curnis A,Senatore G,Capucci A,Della Bella P,Calvi V,Zanotto G,Caravati F,Maglia G,Manzo M,Santamaria M,Ziacchi M,Lissoni F,Giacopelli D,Gargaro A,Solimene F

    更新日期:2019-07-07 00:00:00

  • Left ventricular dysfunction in Rocky Mountain spotted fever.

    abstract::Rocky Mountain spotted fever is a serious infectious disease that continues to occur with increasing incidence in various areas of the United States. A high case-fatality ratio (11%) persists in spite of availability of adequate chemotherapeutic agents, and the cardiac involvement may play an important role in the fin...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960061006

    authors: Marin-Garcia J

    更新日期:1983-10-01 00:00:00

  • The use of the hepatic pressure maneuver to identify the murmur of tricuspid regurgitation.

    abstract::To enhance the bedside diagnosis of tricuspid regurgitation, the influence of manual pressure applied below the liver on lower left sternal border murmurs was determined in 23 patients. All 23 subjects had right ventriculograms and right atrial phonocardiograms. The sign was positive in 13 cases, including 3 who were ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960060605

    authors: Gooch AS,Cha SD,Maranhao V

    更新日期:1983-06-01 00:00:00

  • Downregulation of peroxisome proliferator-activated receptor-gamma expression in hypertensive atrial fibrillation.

    abstract:BACKGROUND:Numerous evidence has suggested that either hypertension or atrial fibrillation (AF) is associated with systemic inflammation. Peroxisome proliferator-activated receptor-gamma (PPARgamma) has been proved to have anti-inflammatory effects and is implicated as a molecular pathway involved in many cardiovascula...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20566

    authors: Chen X,Bing Z,He J,Jiang L,Luo X,Su Y,Kan B,Huang D,Wei Y

    更新日期:2009-06-01 00:00:00

  • Diagnostic value of poor R-wave progression in electrocardiograms for diabetic cardiomyopathy in type 2 diabetic patients.

    abstract:BACKGROUND:Diabetic cardiomyopathy (DCMP) is a common complication of diabetes and is associated with increased mortality. It has been suggested that a poor R-wave progression in a resting electrocardiogram (ECG) could be a sign of cardiomyopathy. HYPOTHESIS:The aim of this study was primarily to analyze the relations...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/clc.20810

    authors: Bildirici U,Ural D,Acar E,Agacdiken A,Ural E

    更新日期:2010-09-01 00:00:00

  • Exercise worsening of electromechanical disturbances: A predictor of arrhythmia in long QT syndrome.

    abstract:BACKGROUND:Electromechanical (EM) coupling heterogeneity is significant in long QT syndrome (LQTS), particularly in symptomatic patients; EM window (EMW) has been proposed as an indicator of interaction and a better predictor of arrhythmia than QTc. HYPOTHESIS:To investigate the dynamic response of EMW to exercise in ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23132

    authors: Charisopoulou D,Koulaouzidis G,Rydberg A,Michael HY

    更新日期:2019-02-01 00:00:00

  • Adenosine triphosphate and adenosine: perspectives in the acute management of paroxysmal supraventricular tachycardia.

    abstract::Adenosine triphosphate (ATP) and adenosine exert strong and transient depressant effects on the sinoatrial and atrioventricular (AV) nodes of the human heart. The AV nodal effects of these drugs explain their high efficacy in either terminating AV re-entrant supraventricular tachycardia or in slowing ventricular rate ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960080903

    authors: Belhassen B,Pelleg A

    更新日期:1985-09-01 00:00:00

  • "Three-level shock" in ablation-refractory paroxysmal atrial fibrillation.

    abstract::His-bundle ablation is a very effective method to control drug-refractory supraventricular arrhythmias. We present a 69-year-old woman with paroxysmal atrial fibrillation, in whom several attempts of unipolar and bipolar His-bundle ablation were ineffective. Ultimately a stable 2/1 atrioventricular block was induced w...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960100516

    authors: Pop T,Treese N,Erbel R,Von Olshausen K,Meyer J

    更新日期:1987-05-01 00:00:00

  • Antiarrhythmic and proarrhythmic properties of diazepam demonstrated by electrophysiological study in humans.

    abstract::We evaluated the electrophysiological parameters before and after the intravenous infusion of diazepam (0.2 mg/kg) in 20 cardiac patients to investigate the drug's antiarrhythmic effect. Diazepam did not significantly change the arterial pressure. After the intravenous infusion of diazepam, the sinus cycle length sign...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960140507

    authors: Kumagai K,Yamanouchi Y,Matsuo K,Tashiro N,Hiroki T,Arakawa K

    更新日期:1991-05-01 00:00:00

  • The role of cross-sectional echocardiography in the diagnosis of flail mitral leaflet.

    abstract::Cross-sectional echocardiography was performed on two patients with mitral regurgitation in whom M-mode echocardiographic findings were not specific for the etiology of mitral regurgitation. In one patient, flail motion of the free edge of the anterior mitral leaflet into the left atrium was demonstrated only by cross...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960010206

    authors: Ogawa S,Mardelli TJ,Hubbard FE

    更新日期:1978-08-01 00:00:00

  • Deciphering the sinus tachycardias.

    abstract::Sinus tachycardia is the most common rhythm disturbance encountered in clinical practice. Primary sinus tachycardia without an underlying secondary cause, despite often being associated with troublesome symptoms, is often neglected leading to multiple consultations and frustration on part of both the practitioner and ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960280603

    authors: Yusuf S,Camm AJ

    更新日期:2005-06-01 00:00:00

  • Marked low-density lipoprotein cholesterol reduction below current national cholesterol education program targets provides the greatest reduction in carotid atherosclerosis.

    abstract:BACKGROUND:Current National Cholesterol Education Program (NCEP) guidelines recognize low-density lipoprotein cholesterol (LDL-C) below 100 mg/dl as an optimal level. Evidence supporting this is scant. Both LDL-C and C reactive protein (CRP) are known correlates of atherosclerosis progression. HYPOTHESIS:We examined t...

    journal_title:Clinical cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/clc.4960270105

    authors: Kent SM,Coyle LC,Flaherty PJ,Markwood TT,Taylor AJ

    更新日期:2004-01-01 00:00:00

  • Rest myocardial perfusion imaging in a patient with atypical chest pain and a nondiagnostic electrocardiogram.

    abstract::ACC/AHA guidelines assign a class I indication for use of myocardial perfusion imaging (MPI) for the evaluation of chest pain in patients with acute coronary syndromes and a nondiagnostic ECG. However, MPI is not a widely used modality for the evaluation of patients who present to the ER with chest pain and an interme...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20549

    authors: Grube H,Rosenblatt J

    更新日期:2010-02-01 00:00:00

  • Thallium-201 perfusion imaging with atrial pacing or dipyridamole stress testing for evaluation of cardiac risk prior to nonvascular surgery.

    abstract::Preoperative assessment of cardiac risk using thallium-201 scintigraphy and atrial pacing (n = 42) or dipyridamole stress testing (n = 35) was performed in 77 patients (mean age 65 +/- 7 years), who subsequently underwent elective nonvascular surgery. All patients were at low cardiac risk by clinical criteria; none co...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960130905

    authors: Stratmann HG,Mark AL,Williams GA

    更新日期:1990-09-01 00:00:00

  • Percutaneous mitral commissurotomy using the metallic valvulotome technique in a critically ill adult.

    abstract::A 25-year-old man presented with cardiogenic shock secondary to rheumatic mitral stenosis. Despite aggressive medical treatment he continued to deteriorate. This report describes the successful use of the metallic valvulotome technique for mitral commissurotomy in the context of a critically ill patient. ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960270616

    authors: Ward DE,Tanner MA

    更新日期:2004-06-01 00:00:00

  • Eicosapentaenoic acid therapy is associated with decreased coronary plaque instability assessed using optical frequency domain imaging.

    abstract:BACKGROUND:The relationship between eicosapentaenoic acid (EPA) therapy and coronary plaque stability assessed by optical frequency domain imaging (OFDI) has not been thoroughly described. HYPOTHESIS:EPA therapy is associated with decreased plaque instability in patients undergoing percutaneous coronary intervention (...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23185

    authors: Konishi T,Sunaga D,Funayama N,Yamamoto T,Murakami H,Hotta D,Nojima M,Tanaka S

    更新日期:2019-06-01 00:00:00

  • Controversies in hypertension: mild hypertension, isolated systolic hypertension, and the choice of a step one drug.

    abstract::The realization that cardiovascular morbidity and mortality increases in patients with mild elevation of either systolic or diastolic blood pressure has led to a consideration to treat millions of patients with mild diastolic or isolated systolic hypertension. The cost of administering a successful antihypertensive tr...

    journal_title:Clinical cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1002/clc.4960060101

    authors: Cressman MD,Gifford RW Jr

    更新日期:1983-01-01 00:00:00

  • Prognostic value of C-reactive protein, fibrinogen, interleukin-6, and macrophage colony stimulating factor in severe unstable angina.

    abstract:BACKGROUND:Inflammatory process plays an important role in the pathogenesis of acute coronary syndromes. HYPOTHESIS:The study was undertaken to evaluate whether admission levels of C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6). and macrophage colony stimulating factor (MCSF) can predict short-term prognos...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960251106

    authors: Rallidis LS,Zolindaki MG,Manioudaki HS,Laoutaris NP,Velissaridou AH,Papasteriadis EG

    更新日期:2002-11-01 00:00:00

  • Acquired coronary cameral fistulas: are these collaterals losing their destination?

    abstract:BACKGROUND:The majority of coronary cameral fistulas (CCFs) are congenital in origin. On the other hand, acquired coronary cameral fistulas, having various etiopathogenic origins, are increasingly recognized. HYPOTHESIS:The aim of this study was to assess the possible involvement of coronary atherosclerosis in the pat...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960220409

    authors: Said SA,van der Werf T

    更新日期:1999-04-01 00:00:00

  • Anatomy, histology, and pathology of coronary arteries: a review relevant to new interventional and imaging techniques--Part III.

    abstract::In the last 15 years, intense interest has focused on various interventional, pharmacologic, and mechanical forms of therapy for the treatment of atherosclerotic coronary artery disease. Many techniques and devices (dilating balloons, perfusion catheters, thermal probes and balloons, lasers, atherectomy devices, stent...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960150812

    authors: Waller BF,Orr CM,Slack JD,Pinkerton CA,Van Tassel JV,Peters T

    更新日期:1992-08-01 00:00:00

  • Aortic dissection in childhood and adolescence: an analysis of occurrences over a 10-year interval in New York State.

    abstract:BACKGROUND:Rarely occurring in the pediatric and adolescent population, aortic dissection is a condition with many predisposing factors. Previous studies have suggested that congenital cardiovascular disorders are the most common predisposing conditions. Trauma-associated aortic dissection is considered a rare occurren...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20383

    authors: Fikar CR,Fikar R

    更新日期:2009-06-01 00:00:00

  • Neuroleptanalgesia in acute myocardial infarction: effects of hemodynamic parameters and plasma catecholamines.

    abstract::The use of neuroleptanalgesia in acute myocardial infarction offers the possibility of reducing pain and emotional stress. The influence of such treatment on hemodynamic parameters (heart rate, cardiac output, stroke volume, peripheral resistance, systemic blood pressure, and pulmonary pressure) and on the plasma leve...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960040505

    authors: Magometschnigg D,Hörtnagl H,Gassner A,Hammerle AF,Kleinberger G,Lenzhofer R,Lochs H,Pall H,Pichler M

    更新日期:1981-09-01 00:00:00

  • Improvement of exercise capacity after nifedipine in patients with Eisenmenger syndrome complicating ventricular septal defect.

    abstract::We investigated the potential benefit of a preferential pulmonary vasodilatory effect of nifedipine in 4 patients with Eisenmenger syndrome complicating ventricular septal defect. First-pass radionuclide scan was performed at rest to measure intracardiac shunting before and after nifedipine. Two hours after 20 mg subl...

    journal_title:Clinical cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1002/clc.4960141205

    authors: Wong CK,Yeung DW,Lau CP,Cheng CH,Leung WH

    更新日期:1991-12-01 00:00:00

  • Recent advances in dobutamine stress echocardiography.

    abstract::Dobutamine stress echocardiography (DSE) is a reliable cardiac risk stratifier that has widespread applicability because of its clinical accuracy and cost effectiveness. Dobutamine has positive inotropic and chronotropic effects and is commonly used in patients who cannot exercise or achieve an adequate heart rate res...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960230804

    authors: Usher BW Jr,O'Brien TX

    更新日期:2000-08-01 00:00:00

  • Unexpected instant death following successful coronary artery bypass graft surgery (and other clinical settings): atrial fibrillation, quinidine, procainamide, et cetera, and instant death.

    abstract::Primum non nocere. Atrial fibrillation (AF) occurs commonly following coronary artery bypass graft surgery, although new onset atrial fibrillation in this setting is usually transient. When AF reverts or is converted to sinus rhythm it is unlikely to recur, whether or not the patient takes preventive medication. As no...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960211004

    authors: Humphries JO

    更新日期:1998-10-01 00:00:00