Abstract:
:Pathophysiology of malignant hypertension, of which underlying disease was essential hypertension (EHT) in 33 cases and chronic glomerulonephritis (CGN) in 26 cases, was studied with reference to the renin-angiotensin system. Plasma renin activity (PRA) was significantly higher in the EHT than in the CGN group, and angiotensin II antagonist [Sar1, Ile8]angiotensin II (AIIA) induced a significant lowering of blood pressure only in the former group. PRA was linearly correlated with both pretreatment mean blood pressure (MBP, r = 0.474, n = 29, p less than 0.01) and serum creatinine (r = 0.540, n = 29, p less than 0.01) in the EHT group but not in CGN patients, although there was an inverse correlation between PRA and serum sodium in both groups. Multiple regression analysis revealed that PRA was independently related to MBP, serum creatinine, and serum sodium in the EHT group, but not in the CGN group. These results suggest that the renin-angiotensin system plays a significant role in elevating blood pressure and deteriorating renal function in malignant hypertension derived from EHT, but it is less important in CGN related hypertension.
journal_name
Clin Cardioljournal_title
Clinical cardiologyauthors
Kawazoe N,Eto T,Abe I,Takishita S,Ueno M,Kobayashi K,Uezono K,Muratani H,Kimura Y,Tomita Ydoi
10.1002/clc.4960100911subject
Has Abstract,Author List Incompletepub_date
1987-09-01 00:00:00pages
513-8issue
9eissn
0160-9289issn
1932-8737journal_volume
10pub_type
杂志文章abstract:BACKGROUD:The association between underlying comorbidities and cardiac injury and the prognosis in coronavirus disease 2019 (COVID-19) patients was assessed in this study. HYPOTHESIS:The underlying comorbidities and cardiac injury may be associated with the prognosis in COVID-19 patients. METHODS:A systematic search ...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.23465
更新日期:2020-12-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
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abstract::The effects of monotherapy with atenolol or diltiazem-SR on blood pressure, 24-h blood pressure (BP) load, and exercise capacity were tested in patients with mild to moderate (stages I and II) essential hypertension. After 3-week single-blind placebo therapy, patients with sitting diastolic blood pressure (SDBP) of 94...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1997-03-01 00:00:00
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journal_title:Clinical cardiology
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更新日期:1992-02-01 00:00:00
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更新日期:2013-07-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
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更新日期:1985-09-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20462
更新日期:2009-11-01 00:00:00
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更新日期:1997-12-01 00:00:00
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更新日期:2010-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/clc.20387
更新日期:2009-05-01 00:00:00
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journal_title:Clinical cardiology
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doi:10.1002/clc.4960101114
更新日期:1987-11-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.20518
更新日期:2009-09-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960201021
更新日期:1997-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/clc.4960241306
更新日期:2001-03-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:
更新日期:1989-07-01 00:00:00
abstract::Approaches to the treatment of supraventricular arrhythmias, including atrial fibrillation, atrial flutter, atrial tachycardia, atrioventricular (AV) reentrant tachycardia, and AV nodal reentrant tachycardia, continue to evolve. Within the past two decades, many new and effective treatments have become available. Thes...
journal_title:Clinical cardiology
pub_type: 杂志文章,评审
doi:10.1002/clc.4960171408
更新日期:1994-09-01 00:00:00
abstract::The impact of transient myocardial ischemia on left ventricular function was examined by digital subtraction left ventricular angiography. Contrast medium was injected into the right pulmonary artery before, at 60 seconds of balloon inflation, and 10 minutes after balloon deflation. A total of 69 patients completed th...
journal_title:Clinical cardiology
pub_type: 临床试验,杂志文章
doi:10.1002/clc.4960140808
更新日期:1991-08-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Despite dual antiplatelet therapy, the rate of major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI) remains high. Ex vivo tests of clopidogrel resistance can predict MACE after PCI. The purpose of this study is to evaluate the clinical impact of adjusting phosphorylation ...
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pub_type: 杂志文章,随机对照试验
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更新日期:2011-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/clc.4960290905
更新日期:2006-09-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1002/clc.4960150812
更新日期:1992-08-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960240204
更新日期:2001-02-01 00:00:00
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journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/clc.20501
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND AND HYPOTHESIS:Japan is an aging society, and the number of nonagenarians with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) is increasing, but their outcomes have not been determined fully. METHODS:We prospectively enrolled 767 consecutive patients who underwent TAVI in t...
journal_title:Clinical cardiology
pub_type: 杂志文章,多中心研究
doi:10.1002/clc.23183
更新日期:2019-06-01 00:00:00
abstract::Preoperative assessment of cardiac risk using thallium-201 scintigraphy and atrial pacing (n = 42) or dipyridamole stress testing (n = 35) was performed in 77 patients (mean age 65 +/- 7 years), who subsequently underwent elective nonvascular surgery. All patients were at low cardiac risk by clinical criteria; none co...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960130905
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Left ventricular ejection fraction (LVEF) has shown to predict outcomes in patients with heart failure (HF). Left ventricular recovery (LVR) has shown to improve prognosis. HYPOTHESIS:Guideline-directed medical therapy will predict LVR in patients with HF and reduced LVEF. METHODS:We studied 244 patients w...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.22937
更新日期:2018-06-01 00:00:00
abstract::A total of 140 consecutive patients with acute Q-wave myocardial infarction was evaluated to assess the relationship between different electrocardiographic patterns of evolution and the incidence of recurrent ischemia within 10 days of infarction. Patients were allocated to three groups according to the electrocardiog...
journal_title:Clinical cardiology
pub_type: 杂志文章
doi:10.1002/clc.4960181205
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND:Conventional approaches to management of congestive heart failure (CHF) rely on drugs that increase myocardial contractility or reduce ventricular afterload. These approaches often improve cardiac symptoms and survival, but may be associated with significant deleterious effects. An alternative approach is to...
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pub_type: 杂志文章
doi:10.1002/clc.4960211206
更新日期:1998-12-01 00:00:00