Elevated serum cardiac troponin in non-acute coronary syndrome.

Abstract:

:Cardiac troponins (CTn) are the most sensitive and specific biochemical markers of myocardial injury and risk stratification. The assay for troponin T (cTnI) is standardized, and results obtained from different institutions are comparable. This is not the case with troponin I (cTnT), and clinicians should be aware that each institution must analyze and standardize its own results. Elevated cTn levels indicate cardiac injury, but do not define the mechanical injury. The differentiation of cTn elevation caused by coronary events from those not related to an acute coronary syndrome (ACS) is tiresome, at times vexing, and often costly. Elevation of cTn in non-ACS is a marker of increased cardiac and all-cause morbidity and mortality. The cause of these elevations may involve serious medical conditions that require meticulous diagnostic evaluation and aggressive therapy. At present, there are no guidelines to treat patients with elevated troponin levels and no coronary disease. The current strategy of treatment of patients with elevated troponin and non-ACS involves treating the underlying causes.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Agzew Y

doi

10.1002/clc.20445

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

15-20

issue

1

eissn

0160-9289

issn

1932-8737

journal_volume

32

pub_type

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