Heart involvement in metastatic carcinoid disease.

Abstract:

:Sixteen patients with metastatic carcinoid tumors of ileal or cecal origin were studied in order to evaluate the frequency and degree of cardiac involvement in a nonselected patient group. We have also studied the correlation between plasma hormone levels (e.g., 5-hydroxytryptamine (5-HT) and substance P) and the degree of cardiac involvement. The patients underwent physical examinations, electrocardiograms, chest x-rays, cardiac catheterization, and echocardiography. Plasma levels of 5-HT and substance P were analyzed. Carcinoid heart involvement was found in 3 of 16 patients (19%) but no patient had subjective symptoms associated with heart disease. Four patients (25%) had slight pulmonary hypertension. No left-sided heart lesions were seen. No correlation between blood levels of 5-HT or substance P and heart involvement was found. Eight patients died during the follow-up period, but in none of these was the cause of death cardiac failure. Carcinoid heart disease is not as common in our patients as in patients selected on a cardiological basis described in earlier studies. Echocardiography appears to be the most efficient technique for detection of even subclinical heart involvement and a useful tool for following its progress.

journal_name

Clin Cardiol

journal_title

Clinical cardiology

authors

Törnebrandt K,Eskilsson J,Nobin A

doi

10.1002/clc.4960090104

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

13-9

issue

1

eissn

0160-9289

issn

1932-8737

journal_volume

9

pub_type

杂志文章
  • Global T-wave inversion: limited QT dispersion despite QTc prolongation--a correlate of benignity in patients with strikingly abnormal electrocardiograms.

    abstract:BACKGROUND:The global T-inversion (GTI) electrocardiogram (ECG) is strikingly abnormal with major QTc prolongation, but with a surprisingly good prognosis by Kaplan-Meier curve. This contrasts with most significant QTc prolongations. HYPOTHESIS:This study was undertaken to ascertain QT interval dispersion (QTd) in glo...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960221012

    authors: Desai SA,Mehrok S,Spodick DH

    更新日期:1999-10-01 00:00:00

  • Endothelial function, fibrinolysis, and angiotensin-converting enzyme inhibition.

    abstract::Experimental and clinical studies with angiotensin-converting enzyme (ACE) inhibitors have suggested that these agents may reduce the risk of atherothrombotic events. Recent studies have identified the role of angiotensin II and ACE in the regulation of fibrinolysis. There is now substantial evidence that the renin-an...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:

    authors: Vaughan DE

    更新日期:1997-11-01 00:00:00

  • Statins: a brief summary.

    abstract::Despite a totality of evidence indicating clear benefits of statin therapy in secondary and primary prevention of cardiovascular disease (CVD), a large number of additional trials are currently planned or in progress to help us better understand, treat, and prevent CVD. Both monotherapy and combination statin regimens...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960240707

    authors: Pfeffer MA

    更新日期:2001-01-01 00:00:00

  • Stroke and Systemic Embolism After Successful Ablation of Typical Atrial Flutter.

    abstract:BACKGROUND:Following successful cavotricuspid isthmus (CTI) ablation during typical atrial flutter (AFL), anticoagulation therapy is usually withdrawn. However, potential subsequent atrial fibrillation (AF) in these patients may increase embolic risk in the long term. Embolic rates in this setting have not been clearly...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22538

    authors: Expósito V,Rodríguez-Entem F,González-Enríquez S,Veiga G,Olavarri I,Olalla JJ

    更新日期:2016-06-01 00:00:00

  • Factors associated with the release of cardiac troponin T following percutaneous transluminal coronary angioplasty.

    abstract:BACKGROUND:Recent studies have suggested that immunoassay of cardiac troponin T (cTnT) provides a more sensitive measurement of myocardial necrosis than creatine kinase MB (CK-MB) mass concentration. HYPOTHESIS:The purpose of this study was to compare the release of cTnT and CK-MB isoenzyme in patients undergoing perc...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960191005

    authors: Abbas SA,Glazier JJ,Wu AH,Dupont C,Green SF,Pearsall LA,Waters DD,McKay RG

    更新日期:1996-10-01 00:00:00

  • Management of coronary artery disease in patients undergoing elective abdominal aortic aneurysm open repair.

    abstract:BACKGROUND:The efficacy of prophylactic coronary revascularization with percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery in patients with abdominal aortic aneurysm (AAA) scheduled for open repair surgery remains controversial. HYPOTHESIS:Concomitant coronary artery disease (CAD) ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20335

    authors: Hosokawa Y,Takano H,Aoki A,Inami T,Ogano M,Kobayashi N,Tanabe J,Yokoyama H,Kato T,Takagi H,Umemoto T,Takayama M,Mizuno K

    更新日期:2008-12-01 00:00:00

  • Extraction of an intracardial catheter embolus using combined radiography and transesophageal echocardiography.

    abstract::Embolism of a fragment of a central venous catheter is a serious clinical complication, especially when the fragment cannot be made visible by radiological methods. We report a case where such a fragment could only be localized by transesophageal echocardiography (TEE). With combined use of x-rays and TEE, the cathete...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960110614

    authors: Neumann HP,Hofmann T,Koester W,Billmann P,Kauffmann GW

    更新日期:1988-06-01 00:00:00

  • The effect of a six-week program of yoga and meditation on brachial artery reactivity: do psychosocial interventions affect vascular tone?

    abstract:BACKGROUND:Chronic stress is estimated to increase the risk of cardiovascular (CV) events two-fold. Although stress reduction has been linked to a reduction in CV events, little is known regarding its exact mechanism of benefit. HYPOTHESIS:Yoga and meditation will improve parameters of endothelial function. METHODS:W...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960290905

    authors: Sivasankaran S,Pollard-Quintner S,Sachdeva R,Pugeda J,Hoq SM,Zarich SW

    更新日期:2006-09-01 00:00:00

  • Effects of dichloroacetate in patients with congestive heart failure.

    abstract:BACKGROUND:Conventional approaches to management of congestive heart failure (CHF) rely on drugs that increase myocardial contractility or reduce ventricular afterload. These approaches often improve cardiac symptoms and survival, but may be associated with significant deleterious effects. An alternative approach is to...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960211206

    authors: Lewis JF,DaCosta M,Wargowich T,Stacpoole P

    更新日期:1998-12-01 00:00:00

  • Statins in the elderly: a patient-focused approach.

    abstract::Individuals age >65 years represent the fastest-growing subpopulation in the United States. Although these individuals with the highest cardiovascular risk profile would be anticipated to be the most aggressively treated, paradoxically, treatment and baseline risk are inversely related. Presumably, the elderly populat...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.22338

    authors: Wilmot KA,Khan A,Krishnan S,Eapen DJ,Sperling L

    更新日期:2015-01-01 00:00:00

  • Peripartum cardiomyopathy: A systematic review of the literature.

    abstract::Peripartum cardiomyopathy (PPCM) is a rare cause of heart failure. It is defined as cardiomyopathy that develops in the last month of pregnancy or within 5 months of the postpartum period without an identifiable cause. We conducted a systematic review of literature of prospective studies with a focus on echocardiograp...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.22932

    authors: Asad ZUA,Maiwand M,Farah F,Dasari TW

    更新日期:2018-05-01 00:00:00

  • The effects of varying lengths and powers of CO2 laser pulses transmitted through an optical fiber on atherosclerotic plaques.

    abstract::We have studied the changes induced in atherosclerotic arteries by a CO2 laser beam delivered through a silver halide optical fiber. We found that the crater depth and diameter correlate with the total energy delivered and with the mode of delivery. Short-duration high-power pulses caused shallower and narrower crater...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960090302

    authors: Eldar M,Battler A,Gal D,Rath S,Rotstein Z,Neufeld HN,Akselrod S,Katzir A,Gaton E,Wolman M

    更新日期:1986-03-01 00:00:00

  • Sudden death and its risk factors after atrioventricular junction ablation and pacemaker implantation in patients with atrial fibrillation.

    abstract:BACKGROUND:Although sudden death (SD) is a rare complication after atrioventricular junction (AVJ) ablation and permanent pacemaker implantation, the risk factors leading to this SD remain unknown. The purpose of this study was to investigate SD and its risk factors after ablate-and-pace strategy for rate control in at...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22600

    authors: Wang RX,Lee HC,Li JP,Hodge DO,Cha YM,Friedman PA,Munger TM,Srivathsan K,Pavri BB,Shen WK

    更新日期:2017-01-01 00:00:00

  • Peripheral arterial tonometry for risk stratification in men with coronary artery disease.

    abstract:BACKGROUND:Coronary artery disease (CAD) risk is not fully revealed by traditional risk factors. Identification of a simple, noninvasive tool that allows for detection of high-risk CAD patients and can be applied in large populations and clinical settings would prove valuable. HYPOTHESIS:We sought to test the hypothes...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20705

    authors: Heffernan KS,Karas RH,Patvardhan EA,Jafri H,Kuvin JT

    更新日期:2010-02-01 00:00:00

  • Pulmonary hypertension: newer concepts in diagnosis and management.

    abstract::Pulmonary hypertension comprises a family of disorders occurring as a primary disease or as a complication of a large number of respiratory and cardiac diseases. Pulmonary hypertension is present when pulmonary artery pressure or mean pressure exceeds 30 mmHg or 20 mmHg, respectively. Underlying the hemodynamic change...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960200804

    authors: Moraes D,Loscalzo J

    更新日期:1997-08-01 00:00:00

  • Early presentation of dilated cardiomyopathy as a part of seroconversion illness in human immunodeficiency virus infection.

    abstract::It has been debated whether dilated cardiomyopathy seen in patients with acquired immune deficiency syndrome is caused by the virus itself or by the combination of other factors such as presence of opportunistic pathogens and/or severe immunosuppression. This paper describes the first reported case of a patient with h...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960200815

    authors: Fath-Ordoubadi F,van der Watt MJ,Noble MI

    更新日期:1997-08-01 00:00:00

  • Sinus arrest due to sertraline.

    abstract::Sertraline is a selective serotonin reuptake inhibitor with established safety for the treatment of depression. Among the common adverse effects associated with sertraline are nausea, insomnia, diarrhea, somnolence, and dizziness. Cardiac arrest had not been reported in the literature, although tachycardia was frequen...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20647

    authors: Kocabay G,Yildiz M,Eksi Duran N,Ozkan M

    更新日期:2010-06-01 00:00:00

  • Catheter balloon valvuloplasty of stenotic porcine bioprosthetic valves: Part II: Mechanisms, complications, and recommendations for clinical use.

    abstract::During the last several years dilating balloons have been applied in the treatment of stenotic cardiac valves. This interest has been extended to stenotic porcine bioprosthetic valves. Part I of this review discusses the pathologic changes producing stenotic porcine prosthetic valves. Part II of this review describes ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960140912

    authors: Waller BF,McKay C,VanTassel J,Allen M

    更新日期:1991-09-01 00:00:00

  • Malignant restenosis after primary successful excimer laser coronary angioplasty.

    abstract::In a series of 20 coronary excimer laser angioplasties, two patients presented with a peculiar type of malignant restenosis 6 and 8 weeks after a successful laser angioplasty procedure. One patient had a successful recanalization of an occluded left anterior descending (LAD) coronary artery and the second patient had ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960130606

    authors: Buchwald A,Werner G,Unterberg C,Voth A,Wiegand V

    更新日期:1990-06-01 00:00:00

  • Circadian rhythmic fractal scaling of heart rate variability in health and coronary artery disease.

    abstract:BACKGROUND:In clinical cardiology, heart rate variability is a putative index of autonomic cardiovascular function. Signs of reduced vagal activity are not only associated with an enhanced risk of sudden cardiac death, but such impaired heart rate variability became a new predictor of sudden cardiac death and other mor...

    journal_title:Clinical cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1002/clc.4960200710

    authors: Otsuka K,Cornélissen G,Halberg F

    更新日期:1997-07-01 00:00:00

  • Correlates of bundle-branch block in patients undergoing primary angioplasty for acute myocardial infarction.

    abstract:BACKGROUND:Early reperfusion therapy has reduced the infarct size and mortality rate in patients with acute myocardial infarction (AMI). The occurrence of bundle-branch block in AMI is related to the amount of myocardial damage and the insult to the conduction system. HYPOTHESIS:To evaluate the clinical and angiograph...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960241204

    authors: Sugiura T,Yamasaki F,Hatada K,Nakamura S,Iwasaka T

    更新日期:2001-12-01 00:00:00

  • Adverse reactions to protamine sulfate following cardiac surgery.

    abstract::We report four patients who developed severe adverse reactions to protamine sulfate following cardiac surgery. Two types of reactions were seen. First, an immediate anaphylaxis which is a complement-dependent IgG antibody-mediated reaction. In the literature, 80% of patients who had similar reactions have had previous...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960070305

    authors: Holland CL,Singh AK,McMaster PR,Fang W

    更新日期:1984-03-01 00:00:00

  • Dose-ranging study with a new two-chain rt-PA in patients with acute myocardial infarction: a multicenter trial.

    abstract::Tissue-type plasminogen activator (t-PA) derived from a melanoma cell line was first used in patients with acute myocardial infarction in the early 1980s. Recombinant DNA technology then allowed production of large amounts of t-PA. The TIMI-I trial used a two-chain recombinant (rt-PA) product. A predominantly single-c...

    journal_title:Clinical cardiology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/clc.4960160404

    authors: DeWood MA,Kurnik PB,Jolly MK,Jain AC,Khaja F,Gorfinkel HJ,Morris DL,Satler L,LittleJohn J

    更新日期:1993-04-01 00:00:00

  • QTc interval evaluation in patients with right bundle branch block or bifascicular blocks.

    abstract:BACKGROUND:The right bundle branch block (RBBB) and the bifascicular blocks affect QRS duration in the right precordial leads, which are usually used for QT interval determination. Up to now, there is no clear recommendation how to determine QT interval in patients with RBBB or bifascicular block. HYPOTHESIS:The hypot...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.23389

    authors: Erkapic D,Frommeyer G,Brettner N,Sözener K,Crijns HJGM,Seyfarth M,Hamm CW,Bogossian H

    更新日期:2020-09-01 00:00:00

  • Aortic dissection in childhood and adolescence: an analysis of occurrences over a 10-year interval in New York State.

    abstract:BACKGROUND:Rarely occurring in the pediatric and adolescent population, aortic dissection is a condition with many predisposing factors. Previous studies have suggested that congenital cardiovascular disorders are the most common predisposing conditions. Trauma-associated aortic dissection is considered a rare occurren...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.20383

    authors: Fikar CR,Fikar R

    更新日期:2009-06-01 00:00:00

  • Relation of ultrasonic tissue characterization with integrated backscatter to contractile reserve in patients with chronic coronary artery disease.

    abstract:BACKGROUND:Previous studies have shown that viable but stunned myocardium displays contractile reserve and exhibits cardiac cycle-dependent variations of integrated backscatter (CVIB), whereas infarcted myocardium does not. HYPOTHESIS:This study was designed to clarify whether assessment of the acoustic properties of ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960261010

    authors: Hu X,Wang J,Sun Y,Jiang X,Sun B,Fu H,Guo R

    更新日期:2003-10-01 00:00:00

  • Mitral valve prolapse and partial syndactyly of the hands.

    abstract::A patient is presented who has mitral valve prolapse and syndactyly of the hands. This combination of findings has not been previously reported, but is consistent with one theory of the development of mitral valve prolapse. ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960050306

    authors: Fitzharris JW

    更新日期:1982-03-01 00:00:00

  • Refractory swallowing-induced paroxysmal supraventricular tachycardia.

    abstract::A 51-year-old female with a two-year history of palpitations associated with swallowing was evaluated by intracardiac electrophysiologic studies. Intracardiac recordings documented the presence of an ectopic left atrial focus induced by swallowing with no evidence of accessory pathway conduction. Gastrointestinal eval...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.4960110117

    authors: Ransbottom JC,Mirro MJ

    更新日期:1988-01-01 00:00:00

  • Deciphering the sinus tachycardias.

    abstract::Sinus tachycardia is the most common rhythm disturbance encountered in clinical practice. Primary sinus tachycardia without an underlying secondary cause, despite often being associated with troublesome symptoms, is often neglected leading to multiple consultations and frustration on part of both the practitioner and ...

    journal_title:Clinical cardiology

    pub_type: 杂志文章,评审

    doi:10.1002/clc.4960280603

    authors: Yusuf S,Camm AJ

    更新日期:2005-06-01 00:00:00

  • Fatty Liver, Insulin Resistance, and Obesity: Relationships With Increase in Coronary Artery Calcium Over Time.

    abstract:BACKGROUND:Nonalcoholic fatty liver disease, insulin resistance (IR), and obesity frequently coexist with type 2 diabetes mellitus (DM), but it is uncertain whether these risk factors for vascular disease contribute to a change in atherosclerosis over time, independently of DM status. HYPOTHESIS:We hypothesized that t...

    journal_title:Clinical cardiology

    pub_type: 杂志文章

    doi:10.1002/clc.22529

    authors: Sung KC,Ryu S,Lee JY,Lee SH,Cheong ES,Wild SH,Byrne CD

    更新日期:2016-06-01 00:00:00