Activation of Ca2+-stimulated ATPase by phospholipid N-methylation in cardiac sarcoplasmic reticulum.

abstract：:PerR, a member of Fur family of metal-dependent regulators, is a major peroxide sensor in many Gram positive bacteria, and controls the expression of genes involved in peroxide resistance. Bacillus licheniformis, a close relative to the well-studied model organism Bacillus subtilis, contains three PerR-like proteins (...

journal_title：Biochemical and biophysical research communications

authors： Kim JH,Won YB,Ji CJ,Yang YM,Ryu SH,Ju SY,Kwon Y,Lee YE,Lee JW

更新日期：2017-02-26 00:00:00

abstract：:The process of endochondral ossification is strictly regulated by a variety of extracellular and intracellular factors. Recently, it has become recognized that specific miRNAs are involved in this process by regulating the expression of the relevant genes at the post-transcriptional level. In this present study we obt...

journal_title：Biochemical and biophysical research communications

authors： Sumiyoshi K,Kubota S,Ohgawara T,Kawata K,Nishida T,Shimo T,Yamashiro T,Takigawa M

更新日期：2010-11-12 00:00:00

abstract：:The collagenase from the larvae Hypoderma lineatum is a serine proteinase sequentially related to the trypsin family. The tryptic peptide containing the serine residue of the active site, labelled with [3H] diisopropylfluorophosphate was isolated and determined to be Ser-Pro-Cys-Phe-Gly-Asp-Ser-Gly-Gly-Pro-(Phe-Ser)-L...

journal_title：Biochemical and biophysical research communications

authors： Lecroisey A,Keil B

更新日期：1983-05-16 00:00:00

abstract：:Pancreatic adenocarcinoma is currently one of the leading causes of cancer-related death worldwide. The high rate of mortality in pancreatic cancer patients is due to the inability to detect early-stage disease and the disease being highly refractory to therapy. Gemcitabine has been the standard chemotherapy for advan...

journal_title：Biochemical and biophysical research communications

authors： Ahn HM,Kim DG,Kim YJ

更新日期：2020-06-25 00:00:00

abstract：:The kinetic parameters of several substrates of penicillin acylase from Streptomyces lavendulae have been determined. The enzyme hydrolyses phenoxymethyl penicillin (penicillin V) and other penicillins with aliphatic acyl-chains such as penicillin F, dihydroF, and K. The best substrate was penicillin K (octanoyl penic...

journal_title：Biochemical and biophysical research communications

authors： Torres-Guzmán R,de la Mata I,Torres-Bacete J,Arroyo M,Castillón MP,Acebal C

更新日期：2002-03-01 00:00:00

abstract：:Because the expression of EBNA1 is prevalent in all EBV-associated tumors, it has become one of the most attractive drug targets for the discovery of anti-EBV compounds. In a cell-based reporter system, EBNA1 consistently upregulated the transcription of an oriP-Luc mini-EBV episome by 6- to 8-fold. The treatment of c...

journal_title：Biochemical and biophysical research communications

authors： Chen YL,Tsai HL,Peng CW

更新日期：2012-01-20 00:00:00

abstract：:In order to search for novel estrogen-responsive genes, we performed serial analysis of gene expression (SAGE) for estrogen-treated MCF-7 human breast cancer cells. SAGE analysis of 31,000 and 30,856 tags from non-treated and 17 beta-estradiol (E2)-treated cells for 24 h, respectively, facilitated the identification o...

journal_title：Biochemical and biophysical research communications

authors： Inadera H,Hashimoto S,Dong HY,Suzuki T,Nagai S,Yamashita T,Toyoda N,Matsushima K

更新日期：2000-08-18 00:00:00

abstract：:To date only about 15 abundantly expressed osmoresponsive genes/proteins have been described in rice cultivars. Using in vivo radiolabeling followed by two-dimensional electrophoresis and autoradiography, a record number of at least 35 salinity stress-induced polypeptides (14-90 kDa) and 17 salt stress-repressed polyp...

journal_title：Biochemical and biophysical research communications

authors： Ramani S,Apte SK

更新日期：1997-04-28 00:00:00

abstract：:Rat hearts were perfused for 15min with buffer equilibrated with 0.01% or 0.05% CO. The buffer was equilibrated with 21% O(2) throughout. The ventricular glutathione content decreased by 76% and 84%, 90min post-exposure to 0.01% and 0.05% CO, respectively, compared with 0% CO controls (0.45+/-0.01 micromol/g wet tissu...

journal_title：Biochemical and biophysical research communications

authors： Patel AP,John Moody A,Handy RD,Robert Sneyd J

更新日期：2003-03-07 00:00:00

abstract：:Hyperglycemia-induced podocyte injury plays a vital role in the development of diabetic nephropathy. Sulfiredoxin-1 (Srxn1) is emerging as a cytoprotective protein that protects from various insults in a wide range of cell types. However, whether Srxn1 is involved in regulating hyperglycemia-induced podocyte injury an...

journal_title：Biochemical and biophysical research communications

authors： Shen Y,Chen S,Zhao Y

更新日期：2019-09-03 00:00:00

abstract：:Both the epidermal growth factor receptor (EGFR) and type 1 insulin-like growth factor receptor (IGF1R) require homo- and hetero-dimerisation with their own family members to acquire full function. We recently showed that IGF1R gene silencing led to EGFR hyper-phosphorylation in human breast cancer cells, and hypothes...

journal_title：Biochemical and biophysical research communications

authors： Riedemann J,Takiguchi M,Sohail M,Macaulay VM

更新日期：2007-04-13 00:00:00

abstract：:Organoids mimicking the formation of the brain cortex have been demonstrated to be powerful tools for developmental studies as well as pathological investigations of brain malformations. Here, we report an integrated approach for the quantification of temporal neural production (neurogenic rate) in organoids derived f...

journal_title：Biochemical and biophysical research communications

authors： Kosodo Y,Suetsugu T,Kobayashi TJ,Matsuzaki F

更新日期：2017-01-29 00:00:00

abstract：:We isolated genomic DNA containing the entire sequence of ZF5, which was originally identified by its ability to repress the mouse c-myc promoter and which was characterized as one of the POZ (Poxvirus and zinc finger) proteins. The POZ motif is a protein-protein interaction interface found at the N-terminal region of...

journal_title：Biochemical and biophysical research communications

authors： Yokoro K,Yanagidani A,Obata T,Yamamoto S,Numoto M

更新日期：1998-05-29 00:00:00

abstract：:The interaction of calcyclin with tropomyosin and tropomyosin-actin was studied with fluorescence titrations and photo-reactive crosslinking experiments. Titrations of pyreneiodoacetamide-labeled tropomyosin alone or with actin showed binding of calcyclin to tropomyosin with muM dissociation constants when Ca2+ was pr...

journal_title：Biochemical and biophysical research communications

authors： Golitsina NL,Kordowska J,Wang CL,Lehrer SS

更新日期：1996-03-18 00:00:00

abstract：:The regulatory role of long non-coding RNAs (lncRNAs) in various biological functions has been demonstrated. However, their role in fat deposition and lipid metabolism in pigs remains less understood. To explore the expression profile of lncRNAs in Jinhua and Landrace pigs, we investigated the expression levels of lnc...

journal_title：Biochemical and biophysical research communications

authors： Miao Z,Wang S,Zhang J,Wei P,Guo L,Liu D,Wang Y,Shi M

更新日期：2018-11-30 00:00:00

abstract：:We have established a highly sensitive semi-nested PCR assay for the detection of H. pylori infection using gastric juice samples, which can be aspirated with disposable nasogastric tubes. The primers targeting H. pylori urease A gene were designed based on the sequence conservation analysis of sixteen H. pylori strai...

journal_title：Biochemical and biophysical research communications

authors： Kawamata O,Yoshida H,Hirota K,Yoshida A,Kawaguchi R,Shiratori Y,Omata M

更新日期：1996-02-06 00:00:00

abstract：:Although a large collection of cancer cell lines are useful surrogates for patient samples, the physiological relevance of observed molecular phenotypes in cell lines remains controversial. Because transcriptome data are a representative set of molecular phenotypes in cancers, we systematically analyzed the discrepanc...

journal_title：Biochemical and biophysical research communications

authors： Hong Y,Kim N,Li C,Jeong E,Yoon S

更新日期：2017-05-27 00:00:00

abstract：:Male Djungarian hamsters (Phodopus sungorus; 45 animals per group) were either sham-exposed or exposed to a sinusoidal magnetic field for 56 days (Experiment 1: 50 Hz, 450 microTesla peak; max. dB/dt = 140 mTesla s(-1); 24 hrs day(-1)). Except for day 7, no effects were observed with respect to body weights during exp...

journal_title：Biochemical and biophysical research communications

authors： Niehaus M,Brüggemeyer H,Behre HM,Lerchl A

更新日期：1997-05-29 00:00:00

abstract：:It has been shown that anti-cancer drug induces secretion of serotonin (5-HT) from small intestine which activates serotonin type 3 (5-HT(3)) receptor to cause nausea and vomiting. In general, antagonist for 5-HT(3) receptor is used as anti-emetics during chemotherapy. However, we found that anti-cancer drug irinoteca...

journal_title：Biochemical and biophysical research communications

authors： Nakamura Y,Ishida Y,Yamada T,Shimada S

更新日期：2011-11-18 00:00:00

abstract：:Three unique inhibitors (SPAI-1, -+2, and -3) were first purified from porcine duodenal extract based on the Na+, K+-ATPase inhibitory activity. These peptide inhibitors had four disulfide bridges in common. The sequencing results of their S-carboxymethyl derivatives, lysilendopeptidase fragments, and chymotryptic pep...

journal_title：Biochemical and biophysical research communications

authors： Araki K,Kuroki J,Ito O,Kuwada M,Tachibana S

更新日期：1989-10-16 00:00:00

abstract：:Co3O4 nanoparticles (NPs) are one kind of the important nanomaterials that have the application potential in catalyst, electrochromic devices, sensors, etc. However, their biological effect remains to be detailed. In this study, we investigated the effect of the as-synthesized Co3O4 NPs (15-30 nm) on the growth of mam...

journal_title：Biochemical and biophysical research communications

authors： Wang H,Ren T,Zhu N,Yu Q,Li M

更新日期：2018-11-02 00:00:00

abstract：:Calmodulin (CaM) was reported to interact with PreIQ and IQ of CaV1.2 channels, but to date, no explicit binding sites of CaM were illustrated. Therefore, in the present study, we firstly used MOE (Molecular Operating Environment) for protein-protein docking and we found that the most likely residues of CaM that play ...

journal_title：Biochemical and biophysical research communications

authors： Liu Y,Yan S,Chen S,Zhang J,Shen Y,Su J,He G,Feng R,Shao D,Hao L

更新日期：2020-05-21 00:00:00

abstract：:Helicobacter pylori is a potent carcinogen associated with gastric cancer malignancy. Recently, H. pylori Heat shock protein 60 (HpHSP60) has been reported to promote cancer development by inducing chronic inflammation and promoting tumor cell migration. This study demonstrates a role for HpHSP60 in angiogenesis, a ne...

journal_title：Biochemical and biophysical research communications

authors： Lin CS,He PJ,Hsu WT,Wu MS,Wu CJ,Shen HW,Hwang CH,Lai YK,Tsai NM,Liao KW

更新日期：2010-06-25 00:00:00

abstract：:The effects of intracisternal (ic) injection of recombinant interleukin-1 beta (IL-1) on absolute ethanol-induced gastric necrotic lesions were studied in conscious rats. IL-1 given ic inhibited ethanol-induced gastric lesions. The cytoprotective effect was dose dependent (ED175 ng/rat), long lasting with a maximal ac...

journal_title：Biochemical and biophysical research communications

authors： Robert A,Saperas E,Zhang WR,Olafsson AS,Lancaster C,Tracey DE,Chosay JG,Taché Y

更新日期：1991-02-14 00:00:00

abstract：:Antibodies and fragments thereof are, because of high selectivity for their targets, considered as potential therapeutics and biomarkers for several neurological disorders. However, due to their large molecular size, antibodies/fragments do not easily penetrate into the brain. The aim of the present study was to impro...

journal_title：Biochemical and biophysical research communications

authors： Syvänen S,Edén D,Sehlin D

更新日期：2017-11-04 00:00:00

abstract：:The expression of the transcription factor Sp1 and EGF receptor (EGFR) was examined on human gastric carcinoma cell lines and gastric carcinoma tissues as well as corresponding normal mucosa in order to clarify the mechanism of overexpression of EGFR gene without gene amplification. All 7 carcinoma cell lines expresse...

journal_title：Biochemical and biophysical research communications

authors： Kitadai Y,Yasui W,Yokozaki H,Kuniyasu H,Haruma K,Kajiyama G,Tahara E

更新日期：1992-12-30 00:00:00

abstract：:We present the first direct biochemical evidence for the turnover of intact type VI collagen microfibrils. Matrix-degrading enzymes of the serine proteinase class, including rat mast cell chymases I and II, human mast cell tryptase, neutrophil elastase, cathepsin G and trypsin, were able to catabolize intact type VI c...

journal_title：Biochemical and biophysical research communications

authors： Kielty CM,Lees M,Shuttleworth CA,Woolley D

更新日期：1993-03-31 00:00:00

abstract：:The repair-associated gene XRCC1 was previously cloned by complementing the hamster mutant EM9, which has a high rate of spontaneous SCE and hypersensitivity to DNA damaging agents. In analyzing XRCC1 gene expression, similar levels of steady-state mRNA were found in normal cells, Bloom's syndrome cells with altered S...

journal_title：Biochemical and biophysical research communications

authors： Yoo H,Li L,Sacks PG,Thompson LH,Becker FF,Chan JY

更新日期：1992-07-31 00:00:00

abstract：:RNA polymerase II carboxyl-terminal domain (pol II CTD) phosphatases that can dephosphorylate both Ser2-PO(4) and Ser5-PO(4) of CTD have been identified in animals and yeasts, however, only Ser5-PO(4)-specific CTD phosphatases have been identified in plants. Among predicted Arabidopsis SCP1-like small phosphatases (SS...

journal_title：Biochemical and biophysical research communications

authors： Feng Y,Kang JS,Kim S,Yun DJ,Lee SY,Bahk JD,Koiwa H

更新日期：2010-06-25 00:00:00

abstract：:The rate limiting step in 5-fluorouracil catabolism is catalyzed by the enzyme dihydropyrimidine dehydrogenase. Since degradation of 5-fluorouracil decreases its efficacy in chemotherapy, the inhibition of its catabolism is a promising tool. We investigated the formation of micronuclei in vitro in mouse L5178Y cells. ...

journal_title：Biochemical and biophysical research communications

authors： Stopper H,Kühnel A,Podschun B

更新日期：1994-09-15 00:00:00