A system for recording neural activity chronically and simultaneously from multiple cortical and subcortical regions in nonhuman primates.

abstract：:The effect of peripheral lesions on cerebral somatosensory representations is well studied for experimentally induced amputations and deafferentations acquired later in life. However, few studies have investigated the brain's capacity for plastic changes in congenital malformations. We studied somatosensory-evoked fie...

journal_title：Journal of neurophysiology

authors： Stoeckel MC,Pollok B,Witte OW,Seitz RJ,Schnitzler A

更新日期：2005-02-01 00:00:00

abstract：:Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are responsible for the functional hyperpolarization-activated current (I(h)) in dorsal root ganglion (DRG) neurons, playing an important role in pain processing. We found that the known analgesic loperamide inhibited I(h) channels in rat DRG neurons. ...

journal_title：Journal of neurophysiology

authors： Vasilyev DV,Shan Q,Lee Y,Mayer SC,Bowlby MR,Strassle BW,Kaftan EJ,Rogers KE,Dunlop J

更新日期：2007-05-01 00:00:00

abstract：:The mouse is an important model system for understanding the molecular basis of neuronal signaling and diseases of synaptic communication. However, the best-characterized retinal ribbon-style synapses are those of nonmammalian vertebrates. To remedy this situation, we asked whether it would be feasible to track synapt...

journal_title：Journal of neurophysiology

authors： Zhou ZY,Wan QF,Thakur P,Heidelberger R

更新日期：2006-11-01 00:00:00

abstract：:The mechanical actions of various ankle muscles were changed by surgically crossing or transferring the tendons in kittens. After the kittens grew to adults, both hindlimbs were implanted with multiple electromyogram (EMG) recording and cutaneous nerve stimulation electrodes to compare the activity of altered and norm...

journal_title：Journal of neurophysiology

authors： Loeb GE

更新日期：1999-12-01 00:00:00

abstract：:A previous neurophysiological investigation demonstrated an increase in functional projections of expiratory bulbospinal neurons (EBSNs) in the segment above a chronic lateral thoracic spinal cord lesion that severed their axons. We have now investigated how this plasticity might be manifested in thoracic motoneurons ...

journal_title：Journal of neurophysiology

authors： Ford TW,Anissimova NP,Meehan CF,Kirkwood PA

更新日期：2016-01-01 00:00:00

abstract：:Slow covariations in neuronal resting potentials can lead to artefactually fast cross-correlations in their spike trains. J. Neurophysiol. 80: 3345-3351, 1998. A model of two lateral geniculate nucleus (LGN) cells, which interact only through slow (tens of seconds) covariations in their resting membrane potentials, is...

journal_title：Journal of neurophysiology

authors： Brody CD

更新日期：1998-12-01 00:00:00

abstract：:The ventrolateral preoptic nucleus (VLPO) is a key nucleus involved in the homeostatic regulation of sleep-wakefulness. Little is known, however, about the cellular mechanisms underlying its role in sleep regulation and how the neurotransmitters, such as GABA and noradrenaline (NA), are involved. In the present study ...

journal_title：Journal of neurophysiology

authors： Matsuo S,Jang IS,Nabekura J,Akaike N

更新日期：2003-03-01 00:00:00

abstract：:The synaptic plasticity literature has focused on establishing necessity and sufficiency as two essential and distinct features in causally relating a signaling molecule to plasticity induction, an approach that has been surprisingly lacking in the intrinsic plasticity literature. In this study, we complemented the re...

journal_title：Journal of neurophysiology

authors： Ashhad S,Johnston D,Narayanan R

更新日期：2015-04-01 00:00:00

abstract：:The present paper investigates the sensory-driven modulations of central pattern generator dynamics that can be expected to reproduce human behavior during rhythmic hybrid tasks. We propose a theoretical model of human sensorimotor behavior able to account for the observed data from the ball-bouncing task. The novel c...

journal_title：Journal of neurophysiology

authors： Avrin G,Siegler IA,Makarov M,Rodriguez-Ayerbe P

更新日期：2017-10-01 00:00:00

abstract：:Populations of output neurons in the mammalian olfactory bulb (OB) exhibit distinct, widespread spatial and temporal activation patterns when stimulated with odorants. However, questions remain as to how ensembles of mitral/tufted (M/T) neurons in the mammalian OB represent odorant information. In this report, the sin...

journal_title：Journal of neurophysiology

authors： Lehmkuhle MJ,Normann RA,Maynard EM

更新日期：2006-03-01 00:00:00

abstract：:1. We investigated gamma-aminobutyric acid (GABA) receptors using thin slice patch-clamp techniques in the swellings along axons of posterior pituitary nerve terminals. 2. Activation of the nerve terminal GABAA receptor induced a mean conductance change of 1.5 nS. Normalizing to area gave a mean conductance density of...

journal_title：Journal of neurophysiology

authors： Zhang SJ,Jackson MB

更新日期：1995-03-01 00:00:00

abstract：:Mechanisms that could mitigate the effects of hypoxia on neuronal signaling are incompletely understood. We show that axonal performance of a locust visual interneuron varied depending on oxygen availability. To induce hypoxia, tracheae supplying the thoracic nervous system were surgically lesioned and action potentia...

journal_title：Journal of neurophysiology

authors： Money TG,Sproule MK,Cross KP,Robertson RM

更新日期：2016-09-01 00:00:00

abstract：:The α9-nicotinic acetylcholine receptor (α9-nAChR) subunit is expressed in the vestibular and auditory periphery, and its loss of function could compromise peripheral input from the predominantly cholinergic efferent vestibular system (EVS). A recent study has shown that α9-nAChRs play an important role in short-term ...

journal_title：Journal of neurophysiology

authors： Hübner PP,Khan SI,Migliaccio AA

更新日期：2017-04-01 00:00:00

abstract：:The intrinsic properties of tonically firing neurons in the cochlear nucleus contribute to representing average sound intensity by favoring synaptic integration across auditory nerve inputs, reducing phase locking to fine temporal acoustic structure and enhancing envelope locking. To determine whether tonically firing...

journal_title：Journal of neurophysiology

authors： Kreeger LJ,Arshed A,MacLeod KM

更新日期：2012-11-01 00:00:00

abstract：:Remembered object locations are stored in an eye-fixed reference frame, so that every time the eyes move, spatial representations must be updated for the arm-motor system to reflect the target's new relative position. To date, studies have not investigated how the brain updates these spatial representations during oth...

journal_title：Journal of neurophysiology

authors： Thompson AA,Henriques DY

更新日期：2008-11-01 00:00:00

abstract：:In the auditory system of the big brown bat (Eptesicus fuscus), paired conditioned tonal (CS) and unconditioned leg stimuli (US) for auditory fear conditioning elicit tone-specific plasticity represented by best-frequency (BF) shifts that are augmented by acetylcholine, whereas unpaired CS and US for pseudoconditionin...

journal_title：Journal of neurophysiology

authors： Ji W,Suga N

更新日期：2013-02-01 00:00:00

abstract：:The core region of primate auditory cortex contains a primary and two primary-like fields (AI, primary auditory cortex; R, rostral field; RT, rostrotemporal field). Although it is reasonable to assume that multiple core fields provide an advantage for auditory processing over a single primary field, the differential r...

journal_title：Journal of neurophysiology

authors： Bendor D,Wang X

更新日期：2008-08-01 00:00:00

abstract：:Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms. J. Neurophysiol. 78: 2707-2716, 1997. The relationship between paired-pulse facilitation (PPF) and synaptic potentiation induced by various protocols and their cellular and molecular mechanisms were exam...

journal_title：Journal of neurophysiology

authors： Wang JH,Kelly PT

更新日期：1997-11-01 00:00:00

abstract：:Whereas Kvbeta2 subunits modulate potassium current properties carried by Kv1 channel complexes in heterologous systems, little is known about the contributions of Kvbeta2 subunits to native potassium channel function. Using antisense approaches and in situ recordings from Xenopus embryo spinal cord neurons, we tested...

journal_title：Journal of neurophysiology

authors： Pineda RH,Knoeckel CS,Taylor AD,Estrada-Bernal A,Ribera AB

更新日期：2008-10-01 00:00:00

abstract：:The discharge of muscle spindle afferents from monkey spindle afferents from monkey jaw-closing muscles was studied during mastication of natural foods by extracellular recording from the fibers or cell bodies of the tract and mesencephalic nucleus of the fifth nerve. In all, 39 muscle afferents were studied. The spin...

journal_title：Journal of neurophysiology

authors： Goodwin GM,Luschei ES

更新日期：1975-05-01 00:00:00

abstract：:Feedback and descending projections from higher to lower brain centers play a prominent role in all vertebrate sensory systems. Feedback might be optimized for the specific sensory processing tasks in their target brain centers, but it has been difficult to connect the properties of feedback synapses to sensory tasks....

journal_title：Journal of neurophysiology

authors： Harvey-Girard E,Maler L

更新日期：2013-12-01 00:00:00

abstract：:Visual response properties of neurons in the dorsolateral geniculate nucleus (dLGN) have been well described in several species, but not in rats. Analysis of responses from the unanesthetized rat dLGN will be needed to develop quantitative models that account for visual behavior of rats. We recorded visual responses f...

journal_title：Journal of neurophysiology

authors： Sriram B,Meier PM,Reinagel P

更新日期：2016-06-01 00:00:00

abstract：:Whole cell patch-clamp recordings were used to investigate the contribution of transient, low-threshold calcium currents (I(T)) to firing properties of hamster spinal dorsal horn neurons. I(T) was widely, though not uniformly, expressed by cells in Rexed's laminae I-IV and correlated with the pattern of action potenti...

journal_title：Journal of neurophysiology

authors： Ku WH,Schneider SP

更新日期：2011-11-01 00:00:00

abstract：:A lamprey maintains the dorsal-side-up orientation due to the activity of postural control system driven by vestibular input. Visual input can affect the body orientation: illumination of one eye evokes ipsilateral roll tilt. An important element of the postural network is the reticulospinal (RS) neurons transmitting ...

journal_title：Journal of neurophysiology

authors： Deliagina TG,Fagerstedt P

更新日期：2000-02-01 00:00:00

abstract：:Silencing-induced homeostatic plasticity is usually expressed as a change in the amplitude or the frequency of miniature postsynaptic currents. Here we report that, prolonged (approximately 24 h) silencing of mature (20-22 days in vitro) cultured hippocampal neurons using the voltage-gated sodium channel blocker tetro...

journal_title：Journal of neurophysiology

authors： Sokolova IV,Mody I

更新日期：2008-08-01 00:00:00

abstract：:When the brain has determined the position of a moving object, because of anatomical and processing delays the object will have already moved to a new location. Given the statistical regularities present in natural motion, the brain may have acquired compensatory mechanisms to minimize the mismatch between the perceiv...

journal_title：Journal of neurophysiology

authors： Subramaniyan M,Ecker AS,Patel SS,Cotton RJ,Bethge M,Pitkow X,Berens P,Tolias AS

更新日期：2018-11-01 00:00:00

abstract：:1. Visual attention is often profoundly disturbed in humans after damage to the cortex of the posterior parietal lobe, particularly of the minor hemisphere, with some patients being totally unaware of visual stimuli in the hemifield of extrapersonal space contralateral to the cortical damage. This severe form of visua...

journal_title：Journal of neurophysiology

authors： Lynch JC,McLaren JW

更新日期：1989-01-01 00:00:00

abstract：:The dorsal premotor area (PMd) of monkeys has been implicated in processes relating to movement preparation and movement selection. In the present study, we sought to determine whether PMd neurons that are activated during a delayed reaching task have directional responses that reflect either the target (i.e., the goa...

journal_title：Journal of neurophysiology

authors： Shen L,Alexander GE

更新日期：1997-03-01 00:00:00

abstract：:The fastigial oculomotor region is the output by which the medioposterior cerebellum influences the generation of saccades. Recent inactivation studies reported observations suggesting an involvement in their dynamics (velocity and duration). In this work, we tested this hypothesis in the head-restrained monkey with t...

journal_title：Journal of neurophysiology

authors： Quinet J,Goffart L

更新日期：2015-05-01 00:00:00

abstract：:The musculoskeletal redundancy of the body provides multiple solutions for performing motor tasks. We have proposed that the nervous system solves this unconstrained problem through the recruitment of motor modules or functional muscle synergies that map motor intention to action. Consistent with this hypothesis, we s...

journal_title：Journal of neurophysiology

authors： Torres-Oviedo G,Ting LH

更新日期：2010-06-01 00:00:00