Attenuation of paired-pulse facilitation associated with synaptic potentiation mediated by postsynaptic mechanisms.

abstract：:A previous neurophysiological investigation demonstrated an increase in functional projections of expiratory bulbospinal neurons (EBSNs) in the segment above a chronic lateral thoracic spinal cord lesion that severed their axons. We have now investigated how this plasticity might be manifested in thoracic motoneurons ...

journal_title：Journal of neurophysiology

authors： Ford TW,Anissimova NP,Meehan CF,Kirkwood PA

更新日期：2016-01-01 00:00:00

abstract：:The nucleus of the tractus solitarius (NTS) plays an important role in the control of several autonomic reflex functions and has glutamate and GABA as main neurotransmitters. In this work, we used patch-clamp recordings in transverse slice preparations from rats to study whether the glycine binding site of the N-methy...

journal_title：Journal of neurophysiology

authors： Baptista V,Varanda WA

更新日期：2005-07-01 00:00:00

abstract：:1. A brain slice preparation was used to study the hypoglossal (XII) neuronal response to anoxia. Both intra- and extracellular potassium activities (K+i,K+o) were measured by the use of ion-selective microelectrodes, and K+ flux was assessed by the use of pharmacologic blockers. 2. Extracellular recordings showed tha...

journal_title：Journal of neurophysiology

authors： Jiang C,Haddad GG

更新日期：1991-07-01 00:00:00

abstract：:1. Pulse inputs (similar to tendon jerks) were applied to the human ankle joint with the use of a hydraulic actuator. Inputs of only 1-2 degrees could elicit large responses (> 20% of maximum voluntary contraction). The magnitude of the response depended nonlinearly on a number of factors: the amplitude, direction, an...

journal_title：Journal of neurophysiology

authors： Stein RB,Kearney RE

更新日期：1995-01-01 00:00:00

abstract：:Much has been studied and written about plastic changes in the CNS of humans triggered by events such as limb amputation. However, little is known about the extent to which the original pathways retain residual function after peripheral amputation. Our earlier, acute study on long-term amputees indicated that central ...

journal_title：Journal of neurophysiology

authors： Dhillon GS,Krüger TB,Sandhu JS,Horch KW

更新日期：2005-05-01 00:00:00

abstract：:1. Compartmental models were used to compute the time constants and coefficients of voltage and current transients in hypothetical neurons having tapering dendrites or soma shunt and in a serially reconstructed motoneuron with soma shunt. These time constants and coefficients were used in equivalent cylinder formulas ...

journal_title：Journal of neurophysiology

authors： Holmes WR,Rall W

更新日期：1992-10-01 00:00:00

abstract：:Performance in behavioral tasks is influenced by temporal expectations shaped by the temporal structure of the task. Such implicit temporal preparation is reflected in slow brain potentials and electroencephalographic oscillations and is attributed to interval timing mechanisms that probably depend on intact basal gan...

journal_title：Journal of neurophysiology

authors： Praamstra P,Pope P

更新日期：2007-11-01 00:00:00

abstract：:1. The electrical threshold of the terminations of single group Ia and II afferent fibers was transiently reduced by the antidromic discharge of the initial segment of spinal motoneurons in the cat. 2. This depolarization of the terminals of afferent fibers known to synapse on motoneurons confirms previous observation...

journal_title：Journal of neurophysiology

authors： Curtis DR,Lodge D,Headley PM

更新日期：1979-05-01 00:00:00

abstract：:We evaluated the role of the sodium/glutamate transporter at the synaptic terminals of cone photoreceptors in controlling postsynaptic response kinetics. The strategy was to measure the changes in horizontal cell response rate induced by blocking transporter uptake in cones with dihydrokainate (DHK). DHK was chosen as...

journal_title：Journal of neurophysiology

authors： Gaal L,Roska B,Picaud SA,Wu SM,Marc R,Werblin FS

更新日期：1998-01-01 00:00:00

abstract：:The basal forebrain plays important roles in arousal, learning, and memory by stimulating cortical activation characterized by rhythmic slow theta and high-frequency beta-gamma activities. Although cholinergic neurons play a significant part in these roles, other, including GABAergic, neurons appear to contribute. Usi...

journal_title：Journal of neurophysiology

authors： Manns ID,Alonso A,Jones BE

更新日期：2003-02-01 00:00:00

abstract：:The functional significance of vestibular information for the generation of gaze shifts is controversial and less well established than the vestibular contribution to gaze stability. In this study, we asked seven bilaterally avestibular patients to execute voluntary, whole body pivot turns to visual targets up to 180°...

journal_title：Journal of neurophysiology

authors： Anastasopoulos D,Ziavra N,Bronstein AM

更新日期：2019-11-01 00:00:00

abstract：:We recently reported evidence indicating that selective attention is deployed to a target location in a multi-object display, when the target event (a change of one of the objects) is preceded by subliminal flicker in the gamma range. However, concerns have been raised regarding the stimuli used in this study and the ...

journal_title：Journal of neurophysiology

authors： Cheadle SW,Parton A,Müller HJ,Usher M

更新日期：2011-02-01 00:00:00

abstract：:With experience, an object can become behaviorally relevant and thereby quickly attract our interest when presented in a visual scene. A likely site of these learning effects is anterior inferior temporal (aIT) cortex, where neurons are thought to participate in the filtering of irrelevant information out of complex v...

journal_title：Journal of neurophysiology

authors： Jagadeesh B,Chelazzi L,Mishkin M,Desimone R

更新日期：2001-07-01 00:00:00

abstract：:Primary auditory cortex (A1) neurons are believed not to carry much information about tonal offsets because A1 neurons in barbiturate-anesthetized animals are usually described as having only onset responses. We investigated tonal offset responses in comparison with onset responses in the caudal part of A1 of awake ca...

journal_title：Journal of neurophysiology

authors： Qin L,Chimoto S,Sakai M,Wang J,Sato Y

更新日期：2007-05-01 00:00:00

abstract：:The intermediate and deep layers of the monkey superior colliculus (SC) are known to be important for the generation of saccadic eye movements. Recent studies have also provided evidence that the rostral SC might be involved in the control of pursuit eye movements. However, because rostral SC neurons respond to visual...

journal_title：Journal of neurophysiology

authors： Krauzlis RJ

更新日期：2001-11-01 00:00:00

abstract：:1. Brain ischemia causes excess release and accumulation of glutamate that binds to postsynaptic receptors. This opens ionotropic channels that mediate neuronal depolarization and ionic fluxes that can lead to neuronal death. 2. The CA1 pyramidal cell region of the hippocampus is particularly susceptible to this neuro...

journal_title：Journal of neurophysiology

authors： Andrew RD,Adams JR,Polischuk TM

更新日期：1996-10-01 00:00:00

abstract：:Motoneurons receive synaptic inputs from tens of thousands of connections that cause membrane potential to fluctuate continuously (synaptic noise), which introduces variability in discharge times of action potentials. We hypothesized that the influence of synaptic noise on force steadiness during voluntary contraction...

journal_title：Journal of neurophysiology

authors： Dideriksen JL,Negro F,Enoka RM,Farina D

更新日期：2012-06-01 00:00:00

abstract：:The majority of cerebral signals destined for the cerebellum are handed over by the pontine nuclei (PN), which thoroughly reorganize the neocortical topography. The PN maps neocortical signals of wide-spread origins into adjacent compartments delineated by spatially precise distribution of cortical terminals and posts...

journal_title：Journal of neurophysiology

authors： Möck M,Butovas S,Schwarz C

更新日期：2006-06-01 00:00:00

abstract：:1. The effects of the di- and trivalent trace metal cations, Pb2+, Zn2+, and Al3+, on voltage-activated calcium channel currents recorded from cultured rat dorsal root ganglion neurons were determined. 2. All three cations blocked transient and sustained components of the voltage-gated calcium channel currents elicite...

journal_title：Journal of neurophysiology

authors： Büsselberg D,Platt B,Michael D,Carpenter DO,Haas HL

更新日期：1994-04-01 00:00:00

abstract：:Many neurons within prefrontal cortex exhibit a tonic discharge between visual stimulation and motor response. This delay activity may contribute to movement, memory, and vision. We studied delay activity sent from the frontal eye field (FEF) in prefrontal cortex to the superior colliculus (SC). We evaluated whether t...

journal_title：Journal of neurophysiology

authors： Sommer MA,Wurtz RH

更新日期：2001-04-01 00:00:00

abstract：:Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are incompletely under...

journal_title：Journal of neurophysiology

authors： Estacion M,Vohra BP,Liu S,Hoeijmakers J,Faber CG,Merkies IS,Lauria G,Black JA,Waxman SG

更新日期：2015-09-01 00:00:00

abstract：:Cellular mechanisms underlying defense reactions induced by noxious heat and acids were studied in frogs (Rana pipiens) by measuring whole cell membrane currents in cultured dorsal root ganglion (DRG) neurons. Seventy-eight of 82 DRG neurons exposed to 3-s ramps of increasing temperature to 48 degrees C exhibited an i...

journal_title：Journal of neurophysiology

authors： Kuffler DP,Lyfenko A,Vyklický L,Vlachová V

更新日期：2002-10-01 00:00:00

abstract：:The parafacial respiratory group (pFRG), located in the lateral aspect of the rostroventral lateral medulla, has been described as a conditional expiratory oscillator that emerges mainly in conditions of high metabolic challenges to increase breathing. The convergence of inhibitory and excitatory inputs to pFRG and th...

journal_title：Journal of neurophysiology

authors： Silva JDN,Oliveira LM,Souza FC,Moreira TS,Takakura AC

更新日期：2020-05-01 00:00:00

abstract：:The functional role of sensory input to the motor cortex was studied by interrupting two major input pathways. One was the dorsal column, which sends the input directly through the thalamus to the motor cortex, and the other was the sensory cortex, which transfers its input through association fibers. Removal of the s...

journal_title：Journal of neurophysiology

authors： Asanuma H,Arissian K

更新日期：1984-08-01 00:00:00

abstract：:Human subjects chose between two color-coded reach targets using multicolored checkerboard-like decision cues (DCs) that presented variable amounts of conflicting sensory evidence supporting both target choices. Different DCs contained different numbers of small squares of the two target colors. The most ambiguous DCs...

journal_title：Journal of neurophysiology

authors： Coallier É,Kalaska JF

更新日期：2014-12-01 00:00:00

abstract：:The discovery that neuroligin is a key protein involved in synapse formation offers the unprecedented opportunity to induce functional synapses between neurons and heterologous cells. We took this opportunity recording for the first-time synaptic currents in human embryonic kidney 293 (HEK293) cells transfected with n...

journal_title：Journal of neurophysiology

authors： Fu Z,Washbourne P,Ortinski P,Vicini S

更新日期：2003-12-01 00:00:00

abstract：:M current relaxations recorded in PC12 cells were subjected to nonstationary noise analysis (NSNA) to obtain estimates of single-channel current (i), channel number (N), and open probability (Po) for the channels responsible for M current. The analysis was constrained such that N and single-channel conductance were th...

journal_title：Journal of neurophysiology

authors： Villarroel A

更新日期：1997-04-01 00:00:00

abstract：:Many electrophysiologists view neurotransmitter transporters as tiny vacuum cleaners, operating continuously to lower extracellular neurotransmitter concentration to zero. However, this is not consistent with their known behavior, instead only reducing extracellular neurotransmitter concentration to a finite, nonzero ...

journal_title：Journal of neurophysiology

authors： Richerson GB,Wu Y

更新日期：2003-09-01 00:00:00

abstract：:We presented optic flow and real movement heading stimuli while recording MSTd neuronal activity. Monkeys were alternately engaged in three tasks: visual detection of optic flow heading perturbations, vestibular detection of real movement heading perturbations, and auditory detection of brief tones. Push-button RTs we...

journal_title：Journal of neurophysiology

authors： Page WK,Duffy CJ

更新日期：2018-01-01 00:00:00

abstract：:Movement duration is an integral component of motor control, but nearly all extant optimization models of motor planning prefix duration instead of explaining it. Here we propose a new optimization principle that predicts movement duration. The model assumes that the brain attempts to minimize movement duration under ...

journal_title：Journal of neurophysiology

authors： Tanaka H,Krakauer JW,Qian N

更新日期：2006-06-01 00:00:00