Silencing-induced metaplasticity in hippocampal cultured neurons.

abstract：:We investigated whether heptanol and other long-chain alcohols that are known to block gap junctions interfere with the generation or the propagation of spreading depression (SD). Waves of SD were triggered by micro-injection of concentrated KCl solution in stratum (s.) radiatum of CA1 of rat hippocampal tissue slices...

journal_title：Journal of neurophysiology

authors： Largo C,Tombaugh GC,Aitken PG,Herreras O,Somjen GG

更新日期：1997-01-01 00:00:00

abstract：:The relationship between neck muscle electromyography (EMG) and torsional head rotation (about the nasooccipital axis) is difficult to assess during normal gaze behaviors with the head upright. Here, we induced acute head tilts similar to cervical dystonia (torticollis) in two monkeys by electrically stimulating 20 in...

journal_title：Journal of neurophysiology

authors： Farshadmanesh F,Byrne P,Wang H,Corneil BD,Crawford JD

更新日期：2012-12-01 00:00:00

abstract：:We observed endocytosis in real time in stimulated frog motor nerve terminals by imaging the growth of large membrane infoldings labeled with a low concentration of FM dye. The spatial and temporal information made available by these experiments allowed us to image several new aspects of this synaptic vesicle recyclin...

journal_title：Journal of neurophysiology

authors： Gaffield MA,Romberg CF,Betz WJ

更新日期：2011-08-01 00:00:00

abstract：:Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

journal_title：Journal of neurophysiology

authors： Trexler EB,Li W,Massey SC

更新日期：2005-03-01 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the most common neurological disorders causing memory reduction, particularly short-term memory (STM). We showed that, during TBI-induced inflammation, increased blood content of fibrinogen (Fg) enhanced vascular protein transcytosis and deposition of extravasated Fg in vasculo-a...

journal_title：Journal of neurophysiology

authors： Charkviani M,Muradashvili N,Sulimai N,Lominadze D

更新日期：2020-08-01 00:00:00

abstract：:Inner ear hair cell afferent fiber synapses are capable of transferring information at high rates for long periods of time with extraordinary fidelity. As at other sensory synapses, hair cells rely on graded receptor potentials and unique vesicle trafficking and release properties of ribbon synapses to relay intensity...

journal_title：Journal of neurophysiology

authors： Schnee ME,Castellano-Muñoz M,Ricci AJ

更新日期：2013-07-01 00:00:00

abstract：:This study examined the influence of proprioceptive input from hip flexor muscles on the activity in hip flexors during the swing phase of walking in the decerebrate cat. One hindlimb was partially denervated to remove cutaneous input and afferent input from most other hindlimb muscles. Perturbations to hip movement w...

journal_title：Journal of neurophysiology

authors： Lam T,Pearson KG

更新日期：2001-09-01 00:00:00

abstract：:In this paper, the predictive capability of surface and untargeted intramuscular electromyography (EMG) was compared with respect to wrist-joint torque to quantify which type of measurement better represents joint torque during multiple degrees-of-freedom (DoF) movements for possible application in prosthetic control....

journal_title：Journal of neurophysiology

authors： Kamavuako EN,Scheme EJ,Englehart KB

更新日期：2013-06-01 00:00:00

abstract：:Liolaemus lizards were explored to ascertain whether they would make an amenable model to study single-cell electrophysiology of neurons in the vomeronasal organ (VNO). Despite a rich array of chemosensory-related behaviors chronicled for this genus, no anatomical or functional data exist for the VNO, the organ mediat...

journal_title：Journal of neurophysiology

authors： Labra A,Brann JH,Fadool DA

更新日期：2005-10-01 00:00:00

abstract：:Previous studies have revealed a new form of activity-dependent modulation of the afterhyperpolarization (AHP) in tactile (T) neurons of the leech Hirudo medicinalis. The firing of T cells is characterized by an AHP, which is mainly due to the activity of the Na+/K+ ATPase. Low-frequency repetitive stimulation of T ne...

journal_title：Journal of neurophysiology

authors： Scuri R,Mozzachiodi R,Brunelli M

更新日期：2005-08-01 00:00:00

abstract：:Differential Modulation by Copper and Zinc of P2X2 and P2X4 Receptor Function. The modulation by Cu2+ and Zn2+ of P2X2 and P2X4 receptors expressed in Xenopus oocytes was studied with the two-electrode, voltage-clamp technique. In oocytes expressing P2X2 receptors, both Cu2+ and Zn2+, in the concentration range 1-130 ...

journal_title：Journal of neurophysiology

authors： Xiong K,Peoples RW,Montgomery JP,Chiang Y,Stewart RR,Weight FF,Li C

更新日期：1999-05-01 00:00:00

abstract：:1. We have identified putative histaminergic neurons in the central nervous system of Aplysia californica by light-microscopic autoradiography after uptake of [3H]histamine and by immunohistochemistry with the use of an antibody specific for histamine. 2. In the cerebral ganglion cells previously shown to contain hist...

journal_title：Journal of neurophysiology

authors： Elste A,Koester J,Shapiro E,Panula P,Schwartz JH

更新日期：1990-09-01 00:00:00

abstract：:Olfactory receptor neurons (ORNs) respond to odorants with changes in the action potential firing rate. Excitatory responses, consisting of firing increases, are mediated by a cyclic AMP cascade that leads to the activation of cationic nonselective cyclic nucleotide-gated (CNG) channels and Ca2+-dependent Cl- (ClCa) c...

journal_title：Journal of neurophysiology

authors： Delgado R,Saavedra MV,Schmachtenberg O,Sierralta J,Bacigalupo J

更新日期：2003-09-01 00:00:00

abstract：:A series of studies were carried out to investigate the role of the cerebellar flocculus and ventral paraflocculus in the ability to voluntarily cancel the vestibuloocular reflex (VOR). Squirrel monkeys were trained to pursue moving visual targets and to fixate a head stationary or earth stationary target during passi...

journal_title：Journal of neurophysiology

authors： Belton T,McCrea RA

更新日期：2000-09-01 00:00:00

abstract：:Every time we blink our eyes, the image on the retina goes almost completely dark. And yet we hardly notice these interruptions, even though an external darkening is startling. Intuitively it would seem that if our perception is continuous, then the neuronal activity on which our perceptions are based should also be c...

journal_title：Journal of neurophysiology

authors： Gawne TJ,Martin JM

更新日期：2000-11-01 00:00:00

abstract：:Neurons in the macaque supplementary eye field (SEF) fire at different rates in conjunction with planning saccades in different directions. They also exhibit object-centered spatial selectivity, firing at different rates when the target of the saccade is at the left or right end of a horizontal bar. To compare the rat...

journal_title：Journal of neurophysiology

authors： Moorman DE,Olson CR

更新日期：2007-05-01 00:00:00

abstract：:Leopard frog saccular hair cells exhibit an electrical resonance in response to a depolarizing stimulus that has been proposed to contribute to the tuning properties of the frog sacculus by acting as an electrical band-pass filter. With the whole cell patch-clamp technique, we have investigated the effect of temperatu...

journal_title：Journal of neurophysiology

authors： Smotherman MS,Narins PM

更新日期：1998-01-01 00:00:00

abstract：:Pioneering studies demonstrated that novel degrees of freedom could be controlled individually by directly encoding the firing rate of single motor cortex neurons, without regard to each neuron's role in controlling movement of the native limb. In contrast, recent brain-computer interface work has emphasized decoding ...

journal_title：Journal of neurophysiology

authors： Law AJ,Rivlis G,Schieber MH

更新日期：2014-09-15 00:00:00

abstract：:Second-order vestibular neurons (2 degrees VN) were identified in the isolated frog brain by the presence of monosynaptic excitatory postsynaptic potentials (EPSPs) after separate electrical stimulation of individual vestibular nerve branches. Combinations of one macular and the three semicircular canal nerve branches...

journal_title：Journal of neurophysiology

authors： Straka H,Holler S,Goto F

更新日期：2002-11-01 00:00:00

abstract：:It is well known that, typically, saccadic eye movements precede goal-directed hand movements to a visual target stimulus. Also pointing in general is more accurate when the pointing target is gazed at. In this study, it is hypothesized that saccades are not only preceding pointing but that gaze also is stabilized dur...

journal_title：Journal of neurophysiology

authors： Neggers SF,Bekkering H

更新日期：2000-02-01 00:00:00

abstract：:A new method is presented based on trinary logic able to check the state of different control variables and synchronously record the physiological and behavioral data of behaving animals and humans. The basic information structure of the method is a time interval of defined maximum duration, called time slice, during ...

journal_title：Journal of neurophysiology

authors： Kutz DF,Marzocchi N,Fattori P,Cavalcanti S,Galletti C

更新日期：2005-06-01 00:00:00

abstract：:Slow covariations in neuronal resting potentials can lead to artefactually fast cross-correlations in their spike trains. J. Neurophysiol. 80: 3345-3351, 1998. A model of two lateral geniculate nucleus (LGN) cells, which interact only through slow (tens of seconds) covariations in their resting membrane potentials, is...

journal_title：Journal of neurophysiology

authors： Brody CD

更新日期：1998-12-01 00:00:00

abstract：:Alphabetagamma GABA(A) receptor currents are phasic and desensitizing, whereas alphabetadelta GABA(A) receptor currents are tonic and have no fast desensitization. alphabetagamma receptors are subsynaptic and mediate phasic inhibition, whereas alphabetadelta receptors are extra- or perisynaptic and mediate tonic inhib...

journal_title：Journal of neurophysiology

authors： Feng HJ,Macdonald RL

更新日期：2004-09-01 00:00:00

abstract：:Synchronization of local and distributed neuronal assemblies is thought to underlie fundamental brain processes such as perception, learning, and cognition. In neurological disease, neuronal synchrony can be altered and in epilepsy may play an important role in the generation of seizures. Linear cross-correlation and ...

journal_title：Journal of neurophysiology

authors： Warren CP,Hu S,Stead M,Brinkmann BH,Bower MR,Worrell GA

更新日期：2010-12-01 00:00:00

abstract：:The synaptic plasticity literature has focused on establishing necessity and sufficiency as two essential and distinct features in causally relating a signaling molecule to plasticity induction, an approach that has been surprisingly lacking in the intrinsic plasticity literature. In this study, we complemented the re...

journal_title：Journal of neurophysiology

authors： Ashhad S,Johnston D,Narayanan R

更新日期：2015-04-01 00:00:00

abstract：:In rats, whisker trimming during development leads to persistent alterations in the function of cortical barrel circuits and to behavioral deficits later in life. Here we examined how whisker trimming begun either at birth (P0) or on postnatal day 12 (P12), around the onset of whisking behavior, affects receptive fiel...

journal_title：Journal of neurophysiology

authors： Shoykhet M,Land PW,Simons DJ

更新日期：2005-12-01 00:00:00

abstract：:The responsiveness of sensory neurons to muscle metabolites is altered under the conditions of insufficient limb blood supply in some diseases, such as peripheral artery disease. The purpose of this study was to examine ATP-induced current with activation of purinergic P2X subtypes P2X₃ and P2X₂/₃ in dorsal root gangl...

journal_title：Journal of neurophysiology

authors： Xing J,Lu J,Li J

更新日期：2013-04-01 00:00:00

abstract：:The properties of the vestibuloocular reflex (VOR) when the axis of rotation is behind the eyes and fixation of a near target is required were studied in the monkey. The magnitude of VOR gain in each eye was found to be above 1.0 and near the ideal value for stabilizing a retinal image. Evidence that this large VOR ga...

journal_title：Journal of neurophysiology

authors： Viirre E,Tweed D,Milner K,Vilis T

更新日期：1986-08-01 00:00:00

abstract：:N-methyl-d-aspartate (NMDA) receptors play crucial roles in glutamate-mediated synaptic transmission and plasticity and are involved in a variety of brain functions. Specific single nucleotide polymorphisms (SNPs) in the genes encoding NMDA receptor subunits have been associated with some neuropsychiatric disorders in...

journal_title：Journal of neurophysiology

authors： Mori F,Ribolsi M,Kusayanagi H,Siracusano A,Mantovani V,Marasco E,Bernardi G,Centonze D

更新日期：2011-10-01 00:00:00

abstract：:The neocortex generates short epochs of persistent activity called up states, which are associated with changes in cellular and network excitability. Using somatosensory thalamocortical slices, we studied the impact of persistent cortical activity during spontaneous up states on intrinsic cellular excitability (input ...

journal_title：Journal of neurophysiology

authors： Rigas P,Castro-Alamancos MA

更新日期：2009-07-01 00:00:00