Abstract：
:Genetic conflicts arise when the evolutionary interests of two genetic elements are not aligned. Conflicts between genomes (e.g. pathogen versus host) or within the same genome (e.g. internal parasitic DNA sequences versus the rest of the host genome) can both foster 'molecular arms races', in which genes on both sides of the conflict rapidly evolve due to bouts of adaptation and counter-adaptation. Importantly, a source of genetic novelty is needed to fuel these arms races. In this review, we highlight gene conversion as a major force in generating the novel alleles on which selection can act. Using examples from both intergenomic and intragenomic conflicts, we feature the mechanisms by which gene conversion facilitates the rapid evolution of genes in conflict.
journal_name
Curr Opin Genet Devjournal_title
Current opinion in genetics & developmentauthors
Daugherty MD,Zanders SEdoi
10.1016/j.gde.2019.07.011subject
Has Abstractpub_date
2019-10-01 00:00:00pages
49-54eissn
0959-437Xissn
1879-0380pii
S0959-437X(19)30047-4journal_volume
58-59pub_type
杂志文章,评审abstract：:The detection of sequence variation with restriction fragment length polymorphisms is advancing our knowledge of plant genetics on several fronts. In the past year, there has been progress in genetic map construction, phylogeny studies, and the dissection of multigenic traits. In addition, new methods that are indepen...
journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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abstract：:Proliferating cells must increase their mass coordinately with cell division. Recent evidence suggests that coupling of cell growth with cell division might be achieved by making synthesis of activators of cell division particularly sensitive to the capacity of the cell's protein synthesis machinery. ...
journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2004.07.011
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journal_title：Current opinion in genetics & development
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更新日期：2002-02-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2005.04.011
更新日期：2005-06-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2015.08.009
更新日期：2015-08-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2006.04.017
更新日期：2006-06-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/0959-437x(95)80004-o
更新日期：1995-12-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2015.01.001
更新日期：2015-06-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2018.05.004
更新日期：2018-10-01 00:00:00
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journal_title：Current opinion in genetics & development
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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更新日期：2004-12-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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更新日期：2001-02-01 00:00:00
abstract：:The transcription factor TFIIH is a versatile, multi-functional protein complex with multiple engagements. Apart from its role in basal transcription, TFIIH is intimately implicated in DNA repair and (probably) in cell cycle control (both of which are required to prevent carcinogenesis) as well as having possible role...
journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/s0959-437x(96)90006-4
更新日期：1996-02-01 00:00:00
abstract：:A number of prokaryotic and eukaryotic genomes are currently being sequenced. Already, the nucleotide sequences of four yeast chromosomes and of 2.2 Mb from Caenorhabditis elegans have been reported. Human genomic sequences have also been used in comparative studies with both mouse and Fugu rubripes. ...
journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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更新日期：1995-06-01 00:00:00
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journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
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abstract：:Identification of new genes involved in muscle disorders has dramatically changed the traditional clinical classification of the large and heterogeneous group of the muscular dystrophies. Results obtained in recent years by positional candidate cloning have demonstrated the role of the sarcolemma and of the nuclear en...
journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/s0959-437x(99)80041-0
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abstract：:Human genetic studies have long been vastly Eurocentric, raising a key question about the generalizability of these study findings to other populations. Because humans originated in Africa, these populations retain more genetic diversity, and yet individuals of African descent have been tremendously underrepresented i...
journal_title：Current opinion in genetics & development
pub_type： 杂志文章,评审
doi：10.1016/j.gde.2018.08.005
更新日期：2018-12-01 00:00:00
