Abstract:
:During development, embryos perform a mesmerizing choreography, which is crucial for the correct shaping, positioning and function of all organs. The cellular properties powering animal morphogenesis have been the focus of much attention. In contrast, much less consideration has been given to the invisible engine constituted by the intercellular fluid. Cells are immersed in fluid, of which the composition and physical properties have a considerable impact on development. In this review, we revisit recent studies from the perspective of the fluid, focusing on basolateral fluid compartments and taking the early mouse and zebrafish embryos as models. These examples illustrate how the hydration levels of tissues are spatio-temporally controlled and influence embryonic development.
journal_name
Curr Opin Genet Devjournal_title
Current opinion in genetics & developmentauthors
Schliffka MF,Maître JLdoi
10.1016/j.gde.2019.06.015subject
Has Abstractpub_date
2019-08-01 00:00:00pages
70-77eissn
0959-437Xissn
1879-0380pii
S0959-437X(19)30021-8journal_volume
57pub_type
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