Are older men more vulnerable to depression than women after losing their spouse? Evidence from three German old-age cohorts (AgeDifferent.de platform).

Abstract:

BACKGROUND:Old age is accompanied by a higher risk of losing a spouse. This study aims to longitudinally investigate the effect of widowhood on depression severity with a special focus on sex differences. We examine depression before and after widowhood in men and women separately to investigate which sex is at greater risk after losing a spouse. METHODS:Data came from the AgeDifferent.de platform, which includes three pooled old age cohort studies. In order to examine factors associated with depression over time, we applied a linear hybrid mixed-effects regression model for the overall sample and analysed additional separate models for men and women. RESULTS:Of 2470 respondents (mean age at baseline 79.2 (SD 3.64) years), 1256 were men. In total, 209 men and 332 women experienced spousal bereavement after baseline. In general, both sexes showed higher depression severity after widowhood. However, there were significant sex differences. Widowed men were more prone to subsequent depression than widowed women. In terms of depression severity, widowed men differed significantly compared to non-widowed men; however, this was not the case for women. LIMITATION:We harmonized three cohort studies which used different measurement scales for depression and different recruitment procedures. CONCLUSION:Our study showed that although both genders suffer from losing a spouse, men are more prone to subsequently develop depressive symptoms. Raising the awareness among practitioners for sex-specific differences as well as developing tailored interventions for both widowed men and women should be considered.

journal_name

J Affect Disord

authors

Förster F,Pabst A,Stein J,Röhr S,Löbner M,Heser K,Miebach L,Stark A,Hajek A,Wiese B,Maier W,Angermeyer MC,Scherer M,Wagner M,König HH,Riedel-Heller SG

doi

10.1016/j.jad.2019.06.047

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

650-657

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(19)30400-8

journal_volume

256

pub_type

杂志文章
  • Risky decision-making in suicide attempters, and the choice of a violent suicidal means: an updated meta-analysis.

    abstract:BACKGROUND:Studies showed disadvantageous decision-making in suicide attempters. The present meta-analysis aims to examine the stability of these findings and related questions. METHODS:EMBASE and Pubmed databases were searched for studies published between 01/01/2000 and 01/01/2020 with an additional search through b...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.11.052

    authors: Perrain R,Dardennes R,Jollant F

    更新日期:2021-02-01 00:00:00

  • Discrepancy in perceived social support and related factors among Chinese college students with and without siblings.

    abstract:BACKGROUND:Whether there is a difference in perceived social support (PSS) and related factors among college students from one- and multiple-child families was unclear. METHODS:We conducted a population-based, cross-sectional study between October 2017 and February 2018, randomly selected college students with sibling...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.07.027

    authors: Xu H,Yan S,Chang Y,Jiang H,Zou L,Gan Y,Gong Y,Cao S,Wang C,Liu JA,Lu Z

    更新日期:2020-11-01 00:00:00

  • Obsessive-compulsive disorder has a reduced placebo (and antidepressant) response compared to other anxiety disorders: A meta-analysis.

    abstract:BACKGROUND:Previous studies have indicated that obsessive-compulsive disorder (OCD) might have a reduced placebo response compared to other anxiety-related disorders including generalized anxiety disorder, panic disorder, post-traumatic stress disorder, and social anxiety disorder. No previous analysis has directly com...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jad.2017.04.068

    authors: Sugarman MA,Kirsch I,Huppert JD

    更新日期:2017-08-15 00:00:00

  • Study of the concurrent validity of the Calgary Depression Scale for Schizophrenics (CDSS).

    abstract::The aim of this study was to investigate the concurrent validity of the French language version of the Calgary Depression Scale for Schizophrenics (CDSS). Ninety-five schizophrenic patients meeting the DSM-III-R criteria were enrolled in the study. The depressive symptoms were evaluated using the Calgary Depression Sc...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(99)00075-0

    authors: Lançon C,Auquier P,Reine G,Bernard D,Toumi M

    更新日期:2000-05-01 00:00:00

  • Repeated administration of antidepressant drugs reduces regional somatostatin concentrations in rat brain.

    abstract::A possible role for somatostatin in affective disorders is suggested by its low concentration in cerebrospinal fluid of patients with depression. Therefore, we studied the regional effects of antidepressant drugs and antimanic agents on somatostatin concentrations in rat brain. Repeated, but not acute, administration ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(92)90078-k

    authors: Kakigi T,Maeda K,Kaneda H,Chihara K

    更新日期:1992-08-01 00:00:00

  • Dimensional psychopathology of depression: detection of an 'activation' dimension in unipolar depressed outpatients.

    abstract:BACKGROUND:Despite the high prevalence of bipolar spectrum disorders, most instruments currently available for the assessment of depression do not explore symptoms of 'activation' such as anger, irritability, aggressiveness, hostility, and psychomotor activation. METHODS:Two samples of adults with unipolar depression ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/S0165-0327(02)00103-9

    authors: Biondi M,Picardi A,Pasquini M,Gaetano P,Pancheri P

    更新日期:2005-02-01 00:00:00

  • Predictors of persistent social impairment among recovered depressed outpatients.

    abstract:BACKGROUND:Though the social functioning of most depressed outpatients improves with effective treatment, a subgroup may remain impaired after recovering from depression. The purpose of this study was to identify predictors of residual social impairment among patients who recovered from depression. METHODS:These data ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(98)00200-6

    authors: Agosti V

    更新日期:1999-10-01 00:00:00

  • Deliberate self harm patients with depressive disorders: treatment and outcome.

    abstract:BACKGROUND:Depression is the most common psychiatric disorder in deliberate self-harm (DSH) patients and in those who commit suicide. The aim of this study was to examine the treatment received by DSH patients with depression and their progress following DSH. METHODS:A representative sample of 106 patients with an ICD...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(01)00317-2

    authors: Haw C,Houston K,Townsend E,Hawton K

    更新日期:2002-06-01 00:00:00

  • Cognitive styles and future depressed mood in early adulthood: the importance of global attributions.

    abstract:BACKGROUND:Cognitive theories of depression suggest that beliefs of low self-worth and the tendency to attribute negative events to causes that are global (widespread rather than specific) and stable (will persist rather than change in the future) are associated with the development of depressed mood. Such theories are...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.08.057

    authors: Pearson RM,Heron J,Button K,Bentall RP,Fernyhough C,Mahedy L,Bowes L,Lewis G

    更新日期:2015-01-15 00:00:00

  • Gender differences in the prevalence of depression: a survey in primary care.

    abstract::Epidemiological surveys demonstrate that unipolar depression is more common in females than in males. Gender-specific cultural and social factors may contribute to the female preponderance. This study explores this possibility in a cross-cultural sample of general-practice patients systematically recruited in the WHO ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(98)00131-1

    authors: Maier W,Gänsicke M,Gater R,Rezaki M,Tiemens B,Urzúa RF

    更新日期:1999-06-01 00:00:00

  • Electrodermal hyporeactivity and antisocial behavior: does anxiety mediate the relationship?

    abstract::Electrodermal hyporeactivity in the anticipation of aversive stimuli is a highly reliable correlate of diagnosed psychopathy and undersocialized aggressive conduct disorder (UACD), and it has been interpreted as reflecting a weak behavioral inhibition system (BIS) as conceptualized in Gray's work (e.g., in: Royce, J.R...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/s0165-0327(00)00336-0

    authors: Fowles DC

    更新日期:2000-12-01 00:00:00

  • Rates of electroconvulsive therapy use in Edinburgh (1992-1997).

    abstract:BACKGROUND:The number of ECT treatments given each year is a topic of interest for psychiatrists, users and politicians, but there are major methodological problems in reported studies of rates of ECT use in the British Isles. The aim was to establish whether or not the use of ECT had fallen between 1992 and 1997. MET...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(98)00144-x

    authors: Glen T,Scott AI

    更新日期:1999-07-01 00:00:00

  • Determinants of access to health care for depression in 49 countries: A multilevel analysis.

    abstract:BACKGROUND:The relative importance of individual and country-level factors influencing access to diagnosis and treatment for depression across the world is fairly unknown. METHODS:We analysed cross-national data from the WHO World Health Surveys. Depression diagnosis and access to health care were ascertained using a ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.02.092

    authors: Araya R,Zitko P,Markkula N,Rai D,Jones K

    更新日期:2018-07-01 00:00:00

  • Forecasting state-level premature deaths from alcohol, drugs, and suicides using Google Trends data.

    abstract:BACKGROUND:Vital statistics on the number of, alcohol-induced death (AICD) drug-induced death (DICD), and suicides at the local-level are only available after a substantial lag of up to two years after the events occur. We (1) investigate how well Google Trends search data explain variation in state-level rates in the ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2016.10.038

    authors: Parker J,Cuthbertson C,Loveridge S,Skidmore M,Dyar W

    更新日期:2017-04-15 00:00:00

  • Comparison of inflammatory cytokine levels among type I/type II and manic/hypomanic/euthymic/depressive states of bipolar disorder.

    abstract:OBJECTIVE:Inflammatory cytokines have been suggested to be the trait or state markers of bipolar disorder, but with inconsistent results. This may be related to small sample sizes and poor control of some important confounding factors. METHODS:Gender/age-matched outpatients with bipolar disorder and normal controls we...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.05.009

    authors: Bai YM,Su TP,Tsai SJ,Wen-Fei C,Li CT,Pei-Chi T,Mu-Hong C

    更新日期:2014-09-01 00:00:00

  • GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.

    abstract:BACKGROUND:Large sample GWAS is needed to identify genetic factors associated with depression. This study used genome-wide genotypic and phenotypic data from the COPDGene study to identify genetic risk factors for depression. METHODS:Data were from 9716 COPDGene subjects with ≥10 pack-year history. Depression was defi...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.09.003

    authors: Heinzman JT,Hoth KF,Cho MH,Sakornsakolpat P,Regan EA,Make BJ,Kinney GL,Wamboldt FS,Holm KE,Bormann N,Robles J,Kim V,Iyer AS,Silverman EK,Crapo JD,Han S,Potash JB,Shinozaki G,COPDGene Investigators.

    更新日期:2019-01-15 00:00:00

  • Social anxiety questionnaire (SAQ): Development and preliminary validation.

    abstract:BACKGROUND:The Social Anxiety Questionnaire (SAQ) was designed to assess five dimensions of social anxiety as posited by the Clark and Wells' (1995; Clark, 2001) cognitive model. METHODS:The development of the SAQ involved generation of an item pool, followed by a verification of content validity and the theorized fac...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.05.036

    authors: Łakuta P

    更新日期:2018-10-01 00:00:00

  • Family history of suicide in manic-depressive patients.

    abstract::Among 231 manic-depressive patients, 18 (7.8%) had a first- or second-degree relative who had committed suicide. There were no significant differences between the unipolar or bipolar patients for a family history of suicide. The literature is reviewed and the possible implications discussed. ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(85)90044-8

    authors: Roy A

    更新日期:1985-03-01 00:00:00

  • Prevalence and association of somatic symptoms in patients with Major Depressive Disorder.

    abstract:BACKGROUND:Painful and non-painful somatic symptoms are often reported in patients with depressive disorder. The proper identification of depression-relevant somatic symptoms is important for the accurate diagnosis of depression, development of treatment strategies and measurement of outcome. The objective of this stud...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jad.2008.01.009

    authors: Vaccarino AL,Sills TL,Evans KR,Kalali AH

    更新日期:2008-10-01 00:00:00

  • Depression in Mongolian women over the first 2 months after childbirth: prevalence and risk factors.

    abstract:BACKGROUND:Social, political and economic changes in Mongolia have followed post-Soviet style government policies and contributed to both increased liberalisation and reduced security in employment and family finances. This is the first study to attempt to assess the prevalence of depression in a population of Mongolia...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2008.11.010

    authors: Pollock JI,Manaseki-Holland S,Patel V

    更新日期:2009-07-01 00:00:00

  • Lithium, anticonvulsants and suicidal behavior in bipolar disorder.

    abstract:BACKGROUND:Lithium has been found to be effective in reducing suicide rates during long term treatment of patients with bipolar disorders. Data on the efficacy of anticonvulsant mood stabilizers in reducing suicide risk are sparse. METHOD:Charts of 140 bipolar patients treated continuously for a minimum of 6 months du...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/s0165-0327(02)00302-6

    authors: Yerevanian BI,Koek RJ,Mintz J

    更新日期:2003-02-01 00:00:00

  • Factor structure and measurement invariance of the Patient Health Questionnaire-9 for female and male primary care patients with major depression in Germany.

    abstract:BACKGROUND:Depression is characterized by gender-specific distinctions, with women being affected more often than men. The Patient Health Questionnaire-9 (PHQ-9) is frequently used to assess depression in primary healthcare. Previous research has yielded heterogeneous findings on the factor structure, and little is kno...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.08.053

    authors: Petersen JJ,Paulitsch MA,Hartig J,Mergenthal K,Gerlach FM,Gensichen J

    更新日期:2015-01-01 00:00:00

  • Lithium ratio and maintenance treatment response.

    abstract::Erythrocyte/plasma lithium ratios were determined in 41 polar manic depressive outpatients maintained on lithium for a mean of 64 months. Sixteen patients experienced affective episodes requiring additional pharmacologic intervention during periods when their plasma lithium averaged 0.7 meq/l or above for at least 3 p...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(82)90005-2

    authors: Kocsis JH,Kantor JS,Lieberman KW,Stokes PE

    更新日期:1982-09-01 00:00:00

  • Does Attention Deficit Hyperactivity Disorder increase the risk of suicide attempts?

    abstract:OBJECTIVE:To determine if Attention Deficit Hyperactivity Disorder (ADHD) is a risk factor for suicide attempts. METHODS:Data were drawn from the National Comorbidity Replication Survey (NCS-R), a nationally representative sample of adults (N=8098). RESULTS:Of the 365 adults with current ADHD, 16% attempted suicide. ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.05.008

    authors: Agosti V,Chen Y,Levin FR

    更新日期:2011-10-01 00:00:00

  • The relationship between the anterior corpus callosum size and prefrontal cortex volume in drug-free depressed patients.

    abstract:INTRODUCTION:An evolving literature suggests a volume reduction and a loss of functional integrity of prefrontal cortex in depressed patients. Interhemispheric prefrontal functional integrity is mediated via the anterior portion of the corpus callosum. Until recently interhemispheric fibers connecting prefrontal cortex...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2012.06.040

    authors: Ozalay O,Calli C,Kitis O,Cagdas Eker M,Donat Eker O,Ozan E,Coburn K,Saffet Gonul A

    更新日期:2013-04-05 00:00:00

  • Psychometric evaluation of a self-report scale to measure adolescent depression: the CESDR-10 in two national adolescent samples in the United States.

    abstract:BACKGROUND:There is a need for brief instruments to screen for depression in adolescents that are valid, reliable and freely available. The aim of this study was to investigate the psychometric properties of a 10-item version of the CESD-R (CESDR-10) in two national adolescent samples. METHODS:Sample 1 consisted of N=...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.02.009

    authors: Haroz EE,Ybarra ML,Eaton WW

    更新日期:2014-04-01 00:00:00

  • Anxiety during the menopausal transition: a systematic review.

    abstract:OBJECTIVE:There have been relatively few studies of the relationship between anxiety and menopause. Despite the paucity of clear evidence, some authors have suggested that the menopausal transition is a time of heightened risk for onset or exacerbation of anxiety symptoms. There is also controversy as to whether anxiet...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/j.jad.2011.06.055

    authors: Bryant C,Judd FK,Hickey M

    更新日期:2012-07-01 00:00:00

  • Anxiety Sensitivity and Arousal Symptom Implicit Association Task Performance: An Event-Related Potential Study of Cognitive Processing of Anxiety-Relevant Stimuli.

    abstract:BACKGROUND:Anxiety sensitivity (AS), or the fear of anxious arousal, is a transdiagnostic risk factor. Despite the proliferation of self-report research showing AS is related to anxiety, cognitive processes underlying AS are poorly understood. Specifically, AS may reflect processes related to early attentional orientat...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.11.067

    authors: Saulnier KG,Huet A,Judah MR,Allan NP

    更新日期:2021-02-01 00:00:00

  • Suicidal ideation and affect lability in single and multiple suicidal attempters with Major Depressive Disorder: An exploratory network analysis.

    abstract:INTRODUCTION:A better understanding of the specific contribution of risk factors to suicidal behavior could arise from analyzing suicidal ideation (SI) in clinical samples, and comparing single versus multiple suicide attempters through contemporary methods allowing complex and dynamical analyses of multiple and simult...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.04.004

    authors: Núñez D,Ulloa JL,Guillaume S,Olié E,Alacreu-Crespo A,Courtet P

    更新日期:2020-07-01 00:00:00

  • Structural white matter alterations in male adults with high functioning autism spectrum disorder and concurrent depressive symptoms; a diffusion tensor imaging study.

    abstract:BACKGROUND:Autism spectrum disorder (ASD), a prevalent developmental condition, is associated with comorbid mood disorders, most importantly depression. Here, we explored the underlying association between brain white matter microstructural integrity, assessed by diffusion tensor imaging (DTI), and depressive symptoms,...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.08.010

    authors: Mohajer B,Masoudi M,Ashrafi A,Mohammadi E,Bayani Ershadi AS,Aarabi MH,Uban KA

    更新日期:2019-12-01 00:00:00