Abstract:
:Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Mishin VP,Patel MC,Chesnokov A,De La Cruz J,Nguyen HT,Lollis L,Hodges E,Jang Y,Barnes J,Uyeki T,Davis CT,Wentworth DE,Gubareva LVdoi
10.3201/eid2510.190607subject
Has Abstractpub_date
2019-10-01 00:00:00pages
1969-1972issue
10eissn
1080-6040issn
1080-6059journal_volume
25pub_type
杂志文章abstract::We investigated an outbreak of encephalitis in Tangail District, Bangladesh. We defined case-patients as persons from the outbreak area in whom fever developed with new onset of seizures or altered mental status from December 15, 2004, through January 31, 2005. Twelve persons met the definition; 11 (92%) died. Serum s...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1212.060732
更新日期:2006-12-01 00:00:00
abstract::A historical study evaluated maternal outcomes in pregnancy complicated by smallpox. The overall case fatality was estimated to be 34.3% (95% confidence interval [CI] 31.4-37.1), and the proportion of miscarriage or premature birth was estimated to be 39.9% (95% CI 36.5-43.2). Vaccination before pregnancy reduced the ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1207.051531
更新日期:2006-07-01 00:00:00
abstract::Since April 2014, invasive pneumococcal disease incidence has increased substantially across North East England, United Kingdom, reversing the decline that followed the 2006 introduction of pneumococcal conjugate vaccines. Significant increases occurred in 23-valent polysaccharide vaccine serotypes and nonvaccine sero...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2301.160897
更新日期:2017-01-01 00:00:00
abstract::After the outbreak in Wuhan, China, we assessed 29,299 workers screened for severe acute respiratory syndrome coronavirus 2 by reverse transcription PCR. We noted 18 (0.061%) cases of asymptomatic infection; 13 turned negative within 8.0 days, and 41 close contacts tested negative. Among 6 contacts who had serologic t...
journal_title:Emerging infectious diseases
pub_type: 信件
doi:10.3201/eid2609.201848
更新日期:2020-09-01 00:00:00
abstract::We used administrative databases to assess babesiosis among elderly persons in the United States by year, sex, age, race, state of residence, and diagnosis months during 2006-2008. The highest babesiosis rates were in Connecticut, Rhode Island, New York, and Massachusetts, and findings suggested babesiosis expansion t...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1801.110305
更新日期:2012-01-01 00:00:00
abstract::An outbreak of influenza A (H3N2) occurred aboard a U.S. Navy ship in February 1996, despite 95% of the crew's having been appropriately vaccinated. Virus isolated from ill crew members was antigenically distinct from the vaccination strain. With an attack rate of 42%, this outbreak demonstrates the potential for rapi...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0703.010320
更新日期:2001-05-01 00:00:00
abstract::This issue of Emerging Infectious Diseases contains 2 articles that report increases in England in the incidence of hospitalizations for specific diseases, one on pneumonias and the other on community-acquired staphylococcal diseases. Both articles report increases in disease among those >65 years of age. ...
journal_title:Emerging infectious diseases
pub_type: 评论,杂志文章
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更新日期:2008-05-01 00:00:00
abstract::We identified a new polyomavirus in skin lesions from a patient with trichodysplasia spinulosa (TS). Apart from TS being an extremely rare disease, little is known of its epidemiology. On the basis of knowledge regarding other polyomaviruses, we anticipated that infections with trichodysplasia spinulosa-associated pol...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1708.110114
更新日期:2011-08-01 00:00:00
abstract::In 2012, a total of 9 cases of hantavirus infection occurred in overnight visitors to Yosemite Valley, Yosemite National Park, California, USA. In the 6 years after the initial outbreak investigation, the California Department of Public Health conducted 11 rodent trapping events in developed areas of Yosemite Valley a...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
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abstract::We documented a 6-fold increase in the frequency of nontuberculous mycobacteria isolated from clinical samples in Botswana during 2011-2014. Because antituberculosis treatment is often initiated only on the basis of acid-fast bacilli smear-positive microscopy results, some patients with nontuberculous mycobacterial in...
journal_title:Emerging infectious diseases
pub_type: 历史文章,杂志文章
doi:10.3201/eid2507.181440
更新日期:2019-07-01 00:00:00
abstract::Hantaviruses are carried by numerous rodent species throughout the world. In 1993, a previously unknown group of hantaviruses emerged in the United States as the cause of an acute respiratory disease now termed hantavirus pulmonary syndrome (HPS). Before than, hantaviruses were known as the etiologic agents of hemorrh...
journal_title:Emerging infectious diseases
pub_type: 杂志文章,评审
doi:10.3201/eid0302.970202
更新日期:1997-04-01 00:00:00
abstract::African swine fever is a highly contagious disease of pigs in Africa. Although its persistence in Senegal may be caused by asymptomatic carriers involved in the domestic transmission cycle, we demonstrated that the soft tick Ornithodoros sonrai can be naturally infected with the causative agent. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1312.071022
更新日期:2007-12-01 00:00:00
abstract::St. Louis encephalitis virus infection was detected in summer 2015 in southern California after an 11-year absence, concomitant with an Arizona outbreak. Sequence comparisons showed close identity of California and Arizona isolates with 2005 Argentine isolates, suggesting introduction from South America and underscori...
journal_title:Emerging infectious diseases
pub_type: 历史文章,杂志文章
doi:10.3201/eid2212.160805
更新日期:2016-12-01 00:00:00
abstract::Antimicrobial resistance rates for shigella, campylobacter, nontyphoidal salmonella, and enterotoxigenic Escherichia coli were compared for Vietnam and Thailand from 1996 to 1999. Resistance to trimethoprim-sulfamethoxazole, ampicillin, chloramphenicol, and tetracycline was common. Quinolone resistance remains low in ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0802.010145
更新日期:2002-02-01 00:00:00
abstract::Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in "Eco-Challenge" multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United St...
journal_title:Emerging infectious diseases
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doi:10.3201/eid0906.020751
更新日期:2003-06-01 00:00:00
abstract::Preventing campylobacteriosis depends on a thorough understanding of its epidemiology. We used case-case analysis to compare cases of Campylobacter coli infection with cases of C. jejuni infection, to generate hypotheses for infection from standardized, population-based sentinel surveillance information in England and...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid0809.010817
更新日期:2002-09-01 00:00:00
abstract::Salmonella enterica bacteria have become increasingly resistant to antimicrobial agents, partly as a result of genes carried on integrons. Clonal expansion and horizontal gene transfer may contribute to the spread of antimicrobial drug-resistance integrons in these organisms. We investigated this resistance and integr...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1503.081131
更新日期:2009-03-01 00:00:00
abstract::During May-August 2016, mumps virus genotype K was detected in 12 Vietnam citizens who entered China at the Shuikou border crossing and 1 girl from China. We provide evidence that mumps genotype K is circulating in Vietnam and was imported to China from Vietnam. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2404.170591
更新日期:2018-04-01 00:00:00
abstract::We conducted a nationwide study of the prevalence of severe acute respiratory syndrome coronavirus 2 infection in the Faroe Islands. Of 1,075 randomly selected participants, 6 (0.6%) tested seropositive for antibodies to the virus. Adjustment for test sensitivity and specificity yielded a 0.7% prevalence. Our findings...
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doi:10.3201/eid2611.202736
更新日期:2020-11-01 00:00:00
abstract::Healthcare workers accounted for a large proportion of persons with severe acute respiratory syndrome (SARS) during the worldwide epidemic of early 2003. We conducted an investigation of healthcare workers exposed to laboratory-confirmed SARS patients in the United States to evaluate infection-control practices and po...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1002.030793
更新日期:2004-02-01 00:00:00
abstract::To understand the clinical and epidemiologic characteristics of pandemic (H1N1) 2009 virus infection, we retrospectively reviewed medical records of 237 patients with laboratory-confirmed cases reported in Shanghai, China, during May-July 2009. Surveillance activities effectively contained the outbreak and provided us...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
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更新日期:2010-06-01 00:00:00
abstract::A >600% increase in monkeypox cases occurred in the Bokungu Health Zone of the Democratic Republic of the Congo during the second half of 2013; this increase prompted an outbreak investigation. A total of 104 possible cases were reported from this health zone; among 60 suspected cases that were tested, 50 (48.1%) case...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2206.150579
更新日期:2016-06-01 00:00:00
abstract::Tick-borne encephalitis virus (TBEV) is an emerging pathogen in Europe and Asia. We investigated TBEV in Kyrgyzstan by collecting small mammals and ticks from diverse localities and analyzing them for evidence of TBEV infection. We found TBEV circulating in Kyrgyzstan much farther south and at higher altitudes than pr...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1705.101183
更新日期:2011-05-01 00:00:00
abstract::To characterize genetic variation of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) transmitted in the Beijing area during the epidemic outbreak of 2003, we sequenced 29 full-length S genes of SARS-CoV from 20 hospitalized SARS patients on our unit, the Beijing 302 Hospital. Viral RNA templates fo...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1005.030875
更新日期:2004-05-01 00:00:00
abstract::Bacillus cereus is typically considered a blood culture contaminant; however, its presence in blood cultures can indicate true bacteremia. We report 4 episodes of B. cereus bacteremia in 3 persons who inject drugs. Multilocus sequence typing showed that the temporally associated infections were caused by unrelated clo...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2209.150647
更新日期:2016-09-01 00:00:00
abstract::We investigated the dynamics of seroconversion in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. During March 29-May 22, 2020, we collected serum samples and associated clinical data from 177 persons in London, UK, who had SARS-CoV-2 infection. We measured IgG against SARS-CoV-2 and compared a...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2701.203074
更新日期:2021-01-01 00:00:00
abstract::To study a 2001 dengue fever outbreak in Iracoubo, French Guiana, we recorded the location of all patients' homes and the date when symptoms were first observed. A geographic information system (GIS) was used to integrate the patient-related information. The Knox test, a classic space-time analysis technique, was used...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1004.030186
更新日期:2004-04-01 00:00:00
abstract::Dobrava-Belgrade virus (DOBV) is a European hantavirus that causes hemorrhagic fever with renal syndrome (HFRS); case-fatality rates in Balkan countries are as high as 12%. To determine causative agents, we examined 126 cases of DOBV-associated HFRS in central and southern European Russia. In central Russia (Lipetsk, ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1404.071310
更新日期:2008-04-01 00:00:00
abstract::We evaluated the epidemiology of relapsing fever from 1971 to 2003 in Israel. In civilians, incidence declined from 0.35 to 0.11 cases per 100,000 persons annually; in military personnel it averaged 6.4 cases per 100,000 persons annually. These data imply that the pathogen and vector continue to exist in Israel. ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid1111.050521
更新日期:2005-11-01 00:00:00
abstract::An estimated one quarter of persons worldwide are infected with Mycobacterium tuberculosis. In 2018, the World Health Organization issued revised guidance on BCG vaccine for high-risk groups. The World Health Organization should consider guiding countries on a case-by-case basis in developing appropriate BCG policies ...
journal_title:Emerging infectious diseases
pub_type: 杂志文章
doi:10.3201/eid2603.191232
更新日期:2020-03-01 00:00:00