Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir1.

Abstract:

:Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ˃ B ˃ C ˃ D. This drug also inhibited influenza A viruses of avian and swine origin, including viruses that have pandemic potential and those resistant to neuraminidase inhibitors.

journal_name

Emerg Infect Dis

authors

Mishin VP,Patel MC,Chesnokov A,De La Cruz J,Nguyen HT,Lollis L,Hodges E,Jang Y,Barnes J,Uyeki T,Davis CT,Wentworth DE,Gubareva LV

doi

10.3201/eid2510.190607

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

1969-1972

issue

10

eissn

1080-6040

issn

1080-6059

journal_volume

25

pub_type

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