A case-case comparison of Campylobacter coli and Campylobacter jejuni infection: a tool for generating hypotheses.

Abstract:

:Preventing campylobacteriosis depends on a thorough understanding of its epidemiology. We used case-case analysis to compare cases of Campylobacter coli infection with cases of C. jejuni infection, to generate hypotheses for infection from standardized, population-based sentinel surveillance information in England and Wales. Persons with C. coli infection were more likely to have drunk bottled water than were those with C. jejuni infection and, in general, were more likely to have eaten pâté. Important differences in exposures were identified for these two Campylobacter species. Exposures that are a risk for infection for both comparison groups might not be identified or might be underestimated by case-case analysis. Similarly, the magnitude or direction of population risk cannot be assessed accurately. Nevertheless, our findings suggest that case-control studies should be conducted at the species level.

journal_name

Emerg Infect Dis

authors

Gillespie IA,O'Brien SJ,Frost JA,Adak GK,Horby P,Swan AV,Painter MJ,Neal KR,Campylobacter Sentinel Surveillance Scheme Collaborators.

doi

10.3201/eid0809.010817

subject

Has Abstract

pub_date

2002-09-01 00:00:00

pages

937-42

issue

9

eissn

1080-6040

issn

1080-6059

journal_volume

8

pub_type

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