Contribution of Streptococcus anginosus to infections caused by groups C and G streptococci, southern India.

Abstract:

:Vellore, a region in southern India, has a high incidence of severe human infections with Beta-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006-2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research.

journal_name

Emerg Infect Dis

authors

Reissmann S,Friedrichs C,Rajkumari R,Itzek A,Fulde M,Rodloff AC,Brahmadathan KN,Chhatwal GS,Nitsche-Schmitz DP

doi

10.3201/eid1604.090448

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

656-63

issue

4

eissn

1080-6040

issn

1080-6059

journal_volume

16

pub_type

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