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Adenosine and autism: a spectrum of opportunities.

Abstract：

:In rodents, insufficient adenosine produces behavioral and physiological symptoms consistent with several comorbidities of autism. In rodents and humans, stimuli postulated to increase adenosine can ameliorate these comorbidities. Because adenosine is a broad homeostatic regulator of cell function and nervous system activity, increasing adenosine's influence might be a new therapeutic target for autism with multiple beneficial effects. This article is part of the Special Issue entitled 'Neurodevelopmental Disorders'.

journal_name

Neuropharmacology

journal_title

Neuropharmacology

authors

Masino SA,Kawamura M Jr,Cote JL,Williams RB,Ruskin DN

doi

10.1016/j.neuropharm.2012.08.013

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

116-21

eissn

0028-3908

issn

1873-7064

pii

S0028-3908(12)00449-2

journal_volume

68

pub_type

杂志文章,评审

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