Separate lung blood flow in anesthetized dogs: a comparative study between electromagnetometry and SF6 and CO2 elimination.

abstract：BACKGROUND:Anesthetic preconditioning (APC) is a clinically important phenomenon in which volatile anesthetics (VAs) protect tissues such as heart against ischemic injury. The mechanism of APC is thought to involve K channels encoded by the Slo gene family, and the authors showed previously that slo-2 is required for A...

journal_title：Anesthesiology

authors： Wojtovich AP,Smith CO,Urciuoli WR,Wang YT,Xia XM,Brookes PS,Nehrke K

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Because the ultimate purpose of new medical knowledge is to achieve improved health outcomes, physicians need to possess and use this knowledge in their practice. The authors introduced enhanced education and individualized feedback to reduce postoperative nausea and vomiting (PONV). The primary objective wa...

journal_title：Anesthesiology

authors： Cohen MM,Rose DK,Yee DA

更新日期：1996-08-01 00:00:00

abstract：:Effects of lidocaine on arterial pressure, heart rate and electrocortical activity were studied in nine fetal lambs at 0.77 to 0.92 gestation (116 to 138 days of gestation; term in sheep is 150 days). Lidocaine was administered into a fetal femoral vein either as a continuous infusion or as a bolus injection. Epilepti...

journal_title：Anesthesiology

authors： Teramo K,Benowitz N,Heymann MA,Rudolph AM

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Fluid resuscitation in hemorrhagic shock aims to restore hemodynamics and repair altered microcirculation. Hemodynamic coherence is the concordant performance of macro- and microcirculation. The present study on fluid therapy in hemorrhagic shock hypothesized that the choice of fluid (0.9% sodium chloride [s...

journal_title：Anesthesiology

authors： Arnemann PH,Hessler M,Kampmeier T,Seidel L,Malek Y,Van Aken H,Morelli A,Rehberg S,Ince C,Ertmer C

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:We describe the anesthetic management for a new surgical procedure: laser ablation of emphysematous bullae via thoracoscope. Although thoracoscopy is not new, this is the first description of a series of patients with bilateral, chronic lung disease who underwent long periods of one-lung ventilation (OLV) du...

journal_title：Anesthesiology

authors： Barker SJ,Clarke C,Trivedi N,Hyatt J,Fynes M,Roessler P

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The myocardial negative inotropic effects of desflurane are less pronounced than those of other halogenated anesthetics, partly because of intramyocardial catecholamine store release. However, the effects of desflurane on aging myocardium are unknown, whereas aging is known to be associated with an attenuati...

journal_title：Anesthesiology

authors： Rozenberg S,Besse S,Amour J,Vivien B,Tavernier B,Riou B

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The authors compare three techniques for insertion of the ProSeal laryngeal mask airway. METHODS:Two hundred forty healthy patients aged 18-80 yr were randomly allocated for ProSeal laryngeal mask airway insertion using the digital, introducer tool (IT), or gum elastic bougie (GEB)-guided techniques. The di...

journal_title：Anesthesiology

authors： Brimacombe J,Keller C,Judd DV

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Reversal of residual neuromuscular blockade by acetylcholinesterase inhibitors (e.g., neostigmine) improves respiratory function. However, neostigmine may also impair muscle strength. We hypothesized that neostigmine administered after recovery of the train-of-four (TOF) ratio impairs upper airway integrity ...

journal_title：Anesthesiology

authors： Herbstreit F,Zigrahn D,Ochterbeck C,Peters J,Eikermann M

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Mice lacking calsequestrin-1 (CASQ1-null), a Ca-binding protein that modulates the activity of Ca release in the skeletal muscle, exhibit lethal hypermetabolic episodes that resemble malignant hyperthermia in humans when exposed to halothane or heat stress. METHODS:Because oxidative species may play a criti...

journal_title：Anesthesiology

authors： Michelucci A,Paolini C,Canato M,Wei-Lapierre L,Pietrangelo L,De Marco A,Reggiani C,Dirksen RT,Protasi F

更新日期：2015-09-01 00:00:00

abstract：:The authors performed a randomized, prospective trial comparing enflurane, halothane, and isoflurane (each administered with nitrous oxide) to establish which inhaled anesthetic produced the fewest complications and the most rapid induction of anesthesia for children undergoing general anesthesia for diagnostic proced...

journal_title：Anesthesiology

authors： Fisher DM,Robinson S,Brett CM,Perin G,Gregory GA

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Obstetrics carries high medical liability risk. Maternal death and newborn death/brain damage were the most common complications in obstetric anesthesia malpractice claims before 1990. As the liability profile may have changed over the past two decades, the authors reviewed recent obstetric claims in the Ame...

journal_title：Anesthesiology

authors： Davies JM,Posner KL,Lee LA,Cheney FW,Domino KB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Although automated closed-loop control systems may improve quality of care, their safety must be proved under extreme control conditions. This study describes a simulation methodology to test automated controllers and its application in a comparison of two published controllers for Bispectral Index (BIS)-gui...

journal_title：Anesthesiology

authors： Struys MM,De Smet T,Greenwald S,Absalom AR,Bingé S,Mortier EP

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although opioids remain the standard therapy for the treatment of postoperative pain, the prevalence of opioid misuse is rising. The extent to which opioid abuse or dependence affects readmission rates and healthcare utilization is not fully understood. It was hypothesized that surgical patients with a histo...

journal_title：Anesthesiology

authors： Gupta A,Nizamuddin J,Elmofty D,Nizamuddin SL,Tung A,Minhaj M,Mueller A,Apfelbaum J,Shahul S

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:We examined the effects of different anesthetics on cerebral oxygenation and systemic hemodynamics in patients undergoing surgery in beach chair position (BCP). Jugular venous bulb oxygen saturation (SjvO2) and regional cerebral tissue oxygen saturation (SctO2) were determined while patients were placed from...

journal_title：Anesthesiology

authors： Jeong H,Jeong S,Lim HJ,Lee J,Yoo KY

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Conflicting opinions are present in the literature regarding the origin of the negative inotropic effect of propofol on the myocardium. This study aims to resolve these discrepancies by investigating the inotropic effects of propofol the L-type calcium channels and the sodium-calcium exchanger (NCX). METHOD...

journal_title：Anesthesiology

authors： de Ruijter W,Stienen GJ,van Klarenbosch J,de Lange JJ

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Work suggests the amnesia from dexmedetomidine (an α2-adrenergic agonist) is caused by a failure of information to be encoded into long-term memory and that dexmedetomidine might differentially affect memory for emotionally arousing material. We investigated these issues in humans using event-related neuroim...

journal_title：Anesthesiology

authors： Hayama HR,Drumheller KM,Mastromonaco M,Reist C,Cahill LF,Alkire MT

更新日期：2012-11-01 00:00:00

abstract：:Thirty-six halogenated Me Et ethers have been synthesized for evaluation as volatile anesthetics. Eleven of the ethers were too unstable to test, and, of the remaining 25, 13 had promising anesthetic properties in mice and are suitable for study in larger animals. Those ethers having one H with at least 2 halogens oth...

journal_title：Anesthesiology

authors： Terrell RC

更新日期：2008-03-01 00:00:00

abstract：:There has been a dramatic growth of scholarly articles in medical education in recent years. Evaluating medical education research requires specific orientation to issues related to format and content. Our goal is to review the quantitative aspects of research in medical education so that clinicians may understand the...

journal_title：Anesthesiology

authors： Ratelle JT,Sawatsky AP,Beckman TJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Whether the fetus can experience pain remains controversial. During the last half of pregnancy, the neuroanatomic connections for nociception are in place, and the human fetus mounts sizable stress responses to physical insults. Analgesia has been recommended for intrauterine procedures or late termination, ...

journal_title：Anesthesiology

authors： Fisk NM,Gitau R,Teixeira JM,Giannakoulopoulos X,Cameron AD,Glover VA

更新日期：2001-10-01 00:00:00

abstract：:The effects of the neodymium-yttrium aluminum garnet (Nd-YAG) laser on several commonly used endotracheal tubes were examined. Six different types of tubes were tested for flammability. Three tubes were clear, transparent polyvinylchloride with black lettering on the surface. One was yellow-green silicone rubber with ...

journal_title：Anesthesiology

authors： Geffin B,Shapshay SM,Bellack GS,Hobin K,Setzer SE

更新日期：1986-11-01 00:00:00

abstract：:Neurophysiologic studies indicate that local anesthetic-induced seizures are generated in subcortical brain structures. The authors utilized a quantitative autoradiographic technique to measure cerebral metabolism during lidocaine-induced seizure activity in rats anesthetized with nitrous oxide. Local cerebral metabol...

journal_title：Anesthesiology

authors： Ingvar M,Shapiro HM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Pentobarbital decreases the gain of the baroreceptor reflex on the order of 50%, and this blunting is caused nearly entirely by decreasing cardioinhibitory parasympathetic activity. The most likely site of action of pentobarbital is the gamma-aminobutyric acid type A (GABA(A)) receptor. The authors tested wh...

journal_title：Anesthesiology

authors： Irnaten M,Walwyn WM,Wang J,Venkatesan P,Evans C,Chang KS,Andresen MC,Hales TG,Mendelowitz D

更新日期：2002-09-01 00:00:00

abstract：:Systolic pressure variation (SPV) is defined as the difference between the maximum and minimum values of systolic blood pressure following a single positive pressure breath. An increase in the SPV is known to occur clinically during hypovolemia. This study aims to quantify SPV during graded hemorrhage in ventilated do...

journal_title：Anesthesiology

authors： Perel A,Pizov R,Cotev S

更新日期：1987-10-01 00:00:00

abstract：:This study reports effects of halothane on tumor cells in vitro. Cells from the human colon cancer cell line HT-29 were exposed to various concentrations of halothane for 8-72 h. The effect of this exposure on this colon cancer cell line, with and without coincubation with the biologic response modifier gamma-interfer...

journal_title：Anesthesiology

authors： Rudnick S,Stevenson GW,Hall SC,Espinoza-Delgado I,Stevenson HC,Longo DL

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Halothane anesthesia causes spindles in the electroencephalogram (EEG), but the cellular and molecular mechanisms generating these spindles remain incompletely understood. The current study tested the hypothesis that halothane-induced EEG spindles are regulated, in part, by pontine cholinergic mechanisms. M...

journal_title：Anesthesiology

authors： Keifer JC,Baghdoyan HA,Lydic R

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Voltage-gated Na channels modulate membrane excitability in excitable tissues. Inhibition of Na channels has been implicated in the effects of volatile anesthetics on both nervous and peripheral excitable tissues. The authors investigated isoform-selective effects of isoflurane on the major Na channel isofor...

journal_title：Anesthesiology

authors： OuYang W,Hemmings HC Jr

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Ketamine is an anesthetic drug. Subanesthetic doses of ketamine have been shown to reduce interleukin-6 concentrations after surgery and to reduce mortality and the production of tumor necrosis factor alpha and interleukin 6 in septic animals. Similarly, adenosine was shown to reduce tumor necrosis factor al...

journal_title：Anesthesiology

authors： Mazar J,Rogachev B,Shaked G,Ziv NY,Czeiger D,Chaimovitz C,Zlotnik M,Mukmenev I,Byk G,Douvdevani A

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) have been found to induce a delayed protective response called preconditioning to subsequent hypoxic/ischemic injury. VA preconditioning has been primarily studied in canine and rodent heart. A more genetically tractable model of VA preconditioning would be extremely useful. Here, ...

journal_title：Anesthesiology

authors： Jia B,Crowder CM

更新日期：2008-03-01 00:00:00

abstract：:This study examined the efficacy of patient-controlled epidural analgesia (PCEA) during labor and compared the suitability of three different PCEA solutions. After establishing effective epidural analgesia with 12 ml of 0.25% bupivacaine, 72 parturients in active labor were randomly assigned to one of four groups: phy...

journal_title：Anesthesiology

authors： Lysak SZ,Eisenach JC,Dobson CE 2nd

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Anesthetic preconditioning (APC) with sevoflurane reduces myocardial ischemia-reperfusion injury. The authors tested whether two brief exposures to sevoflurane would lead to a better preconditioning state than would a single longer exposure and whether dual exposure to a lower (L) concentration of sevofluran...

journal_title：Anesthesiology

authors： Riess ML,Kevin LG,Camara AK,Heisner JS,Stowe DF

更新日期：2004-03-01 00:00:00