Dual exposure to sevoflurane improves anesthetic preconditioning in intact hearts.

abstract：:The ability of contrast echocardiography to assess regional myocardial perfusion during cardiopulmonary bypass in a dog model for coronary artery bypass surgery was evaluated. Sonicated Renograffin-76 microbubbles (meglumin diatrigoate and sodium diatrigoate) were injected into an aortic root proximal to an aortic occ...

journal_title：Anesthesiology

authors： Aronson S,Bender E,Feinstein SB,Heidenreich PH,Ellis J,Dick C,Roizen MF,Karp RB

更新日期：1990-02-01 00:00:00

abstract：:To determine whether disuse atrophy of skeletal muscle results in resistance to pancuronium, the dose response to pancuronium was determined simultaneously in both gastrocnemius muscles of six dogs that had one hind limb immobilized in a plaster cast for one month. Muscle responses were evoked during pentobarbital-nit...

journal_title：Anesthesiology

authors： Gronert GA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Propofol has not been studied directly in animals subject to cerebral ischemia in the conscious state. Strokes are usually induced in animals while they are anesthetized, making it difficult to eliminate anesthetic interactions as a complicating factor. Therefore, to compare the neuroprotective effects of pr...

journal_title：Anesthesiology

authors： Gelb AW,Bayona NA,Wilson JX,Cechetto DF

更新日期：2002-05-01 00:00:00

abstract：:Transient hyperreflexia, the Babinski reflex, and other transient neurologic signs may follow anesthesia in healthy persons. The authors describe the appearance and durations of these signs and relate them to anesthetic agent, time following cessation of anesthesia, and state of arousal. Twenty-nine neurologically nor...

journal_title：Anesthesiology

authors： Rosenberg H,Clofine R,Bialik O

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:Cortical networks generate diverse patterns of rhythmic activity. Theta oscillations (4-12 Hz) are commonly observed during spatial learning and working memory tasks. The authors ask how etomidate, acting predominantly via gamma-aminobutyric acid type A (GABAA) receptors containing beta2 or beta3 subunits, a...

journal_title：Anesthesiology

authors： Drexler B,Roether CL,Jurd R,Rudolph U,Antkowiak B

更新日期：2005-02-01 00:00:00

abstract：:Reversal of the usual relationship between aortic and radial artery pressure can occur in patients following cardiopulmonary bypass. Radial systolic (and often radial mean) pressures were lower, relative to aortic pressure, after cardiopulmonary bypass than before bypass in all 18 patients studied. The systolic pressu...

journal_title：Anesthesiology

authors： Stern DH,Gerson JI,Allen FB,Parker FB

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Recent evidences have documented that several pharmacologic actions of alpha2-adrenoceptor agonists are mediated via activation of not only alpha2-adrenoceptors, but also by imidazoline receptors, which are nonadrenergic receptors in the central nervous system. However, the effect of imidazoline receptors on...

journal_title：Anesthesiology

authors： Kagawa K,Mammoto T,Hayashi Y,Kamibayashi T,Mashimo T,Yoshiya I

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:The authors sought to determine whether subjects with pathophysiological conditions that are characterized by increased concentrations of aldosterone have increased susceptibility to the side effects of neonatal anesthesia with sevoflurane. METHODS:Postnatal day 4-20 (P4-P20) rats were exposed to sevofluran...

journal_title：Anesthesiology

authors： Cao W,Pavlinec C,Gravenstein N,Seubert CN,Martynyuk AE

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Conflicting opinions are present in the literature regarding the origin of the negative inotropic effect of propofol on the myocardium. This study aims to resolve these discrepancies by investigating the inotropic effects of propofol the L-type calcium channels and the sodium-calcium exchanger (NCX). METHOD...

journal_title：Anesthesiology

authors： de Ruijter W,Stienen GJ,van Klarenbosch J,de Lange JJ

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Sugammadex (Org 25969) forms a complex with steroidal neuromuscular blocking agents, thereby reversing neuromuscular block. This study investigated the dose-response relation, safety, and pharmacokinetics of sugammadex to reverse rocuronium-induced block. METHODS:Twenty-seven male surgical patients aged 18-...

journal_title：Anesthesiology

authors： Sorgenfrei IF,Norrild K,Larsen PB,Stensballe J,Ostergaard D,Prins ME,Viby-Mogensen J

更新日期：2006-04-01 00:00:00

abstract：:The effects of increased intracranial pressure (ICP) and increased cardiac output (QT) on the pulmonary vascular response to regional alveolar hypoxia were compared in pentobarbital-anesthetized, closed-chested dogs. A bronchial divider was inserted, the right lung (RL) was continuously ventilated with 100% O2, and th...

journal_title：Anesthesiology

authors： Domino KB,Hlastala MP,Cheney FW

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Intraoperative awareness in patients undergoing general anesthesia is an infrequent but well-described adverse outcome. The reported incidence of this phenomenon is between 0.1% and 0.9%. METHODS:With institutional review board approval, the authors reviewed continuous quality improvement data from 3 yr (20...

journal_title：Anesthesiology

authors： Pollard RJ,Coyle JP,Gilbert RL,Beck JE

更新日期：2007-02-01 00:00:00

abstract：:This study examined whether pain or stress can enhance the analgesic effects of spinally administered opiates. The experiments determined the effects of mechanically produced pain and of the stress of being restrained on the analgesic effects of 0.63 microgram of epidural sufentanil in rats using a tail-withdrawal pro...

journal_title：Anesthesiology

authors： Van den Hoogen RH,Bervoets K,Colpaert FC

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Because oral erythromycin administration has been associated with reduced elimination of alfentanil, suspicion has been raised about related opioids with similar metabolic pathways. A controlled crossover study of sufentanil pharmacokinetics was undertaken to resolve this issue. METHODS:Six subjects had mea...

journal_title：Anesthesiology

authors： Bartkowski RR,Goldberg ME,Huffnagle S,Epstein RH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The Shannon entropy is a standard measure for the order state of sequences. It quantifies the degree of skew of the distribution of values. Increasing hypnotic drug concentrations increase electroencephalographic amplitude. The probability density function of the amplitude values broadens and flattens, there...

journal_title：Anesthesiology

authors： Bruhn J,Lehmann LE,Röpcke H,Bouillon TW,Hoeft A

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Elimination of daily-routine chest radiographs (CXRs) may influence chest computed tomography (CT) and ultrasound practice in critically ill patients. METHODS:This was a retrospective cohort study including all patients admitted to a university-affiliated intensive care unit during two consecutive periods o...

journal_title：Anesthesiology

authors： Kröner A,Binnekade JM,Graat ME,Vroom MB,Stoker J,Spronk PE,Schultz MJ

更新日期：2008-01-01 00:00:00

abstract：:To study the cerebral protective effects of hypothermia in arterial hypoxia, anesthetized (70% N2O), mechanically ventilated rats were cooled to a body temperature of 27 C. Hypoxia was induced by decreasing the oxygen content in the inspired gas mixture either to 6-7 per cent or to 2.5-3 per cent. This reduced mean Pa...

journal_title：Anesthesiology

authors： Carlsson C,Hägerdal M,Siesjö BK

更新日期：1976-01-01 00:00:00

abstract：:The hemodynamic interactions of verapamil and isoflurane were studied in eight dogs. Left ventricular function was analyzed using a right heart bypass preparation to permit rigid hemodynamic control. Hemodynamic studies were performed at 0.7, 1.05, and 1.40% isoflurane before and during the maintenance of two stable l...

journal_title：Anesthesiology

authors： Kates RA,Kaplan JA,Guyton RA,Dorsey L,Hug CC Jr,Hatcher CR

更新日期：1983-08-01 00:00:00

abstract：WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Craniotomy for brain tumor displays significant morbidity and mortality, and no score is available to discriminate high-risk patients. Our objective was to validate a prediction score for postoperative neurosurgical complications...

journal_title：Anesthesiology

authors： Cinotti R,Bruder N,Srairi M,Paugam-Burtz C,Beloeil H,Pottecher J,Geeraerts T,Atthar V,Guéguen A,Triglia T,Josserand J,Vigouroux D,Viquesnel S,Lakhal K,Galliez M,Blanloeil Y,Le Thuaut A,Feuillet F,Rozec B,Asehnoune K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether progressive levels of hypothermia (37, 34, 31, or 28 degrees C) during cardiopulmonary bypass (CPB) in pigs reduce the physiologic and metabolic consequences of global cerebral ischemia. METHODS:Sagittal sinus and cortical microdialysis catheters were inserted ...

journal_title：Anesthesiology

authors： Conroy BP,Lin CY,Jenkins LW,DeWitt DS,Zornow MH,Uchida T,Johnston WE

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Basal cytotoxic activity of NK cells, a subtype of lymphocytes involved in the nonspecific immune response to viruses, tumors, and some bacteria, is altered in the postoperative period. The current study examines the effects of halothane and isoflurane on interferon-induced stimulation of NK cell cytotoxicit...

journal_title：Anesthesiology

authors： Markovic SN,Knight PR,Murasko DM

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Although neuromuscular blocking agents do not cross the blood-brain barrier, they may penetrate the central nervous system under particular circumstances and eventually cause neurotoxic consequences. METHODS:The effects of neuromuscular blocking agents on excitatory and inhibitory transmission in area CA1 o...

journal_title：Anesthesiology

authors： Chiodini FC,Tassonyi E,Fuchs-Buder T,Fathi M,Bertrand D,Muller D

更新日期：1998-04-01 00:00:00

abstract：:The effect of enflurane (2% and 4% inspired) on left ventricular (LV) function were examined in chronically instrumented dogs, both intact and after isolation of their hearts and lungs from the systemic circulation. Enflurane in the intact dogs increased heart rate (32 +/- 5% with 2% and 41 +/- 4% with 4%) and elicite...

journal_title：Anesthesiology

authors： Zimpfer M,Gilly H,Krösl P,Schlag G,Steinbereithner K

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:We examined the effects of different anesthetics on cerebral oxygenation and systemic hemodynamics in patients undergoing surgery in beach chair position (BCP). Jugular venous bulb oxygen saturation (SjvO2) and regional cerebral tissue oxygen saturation (SctO2) were determined while patients were placed from...

journal_title：Anesthesiology

authors： Jeong H,Jeong S,Lim HJ,Lee J,Yoo KY

更新日期：2012-05-01 00:00:00

abstract：:Eighty-six patients undergoing coronary artery bypass graft (n = 63) or intracardiac (n = 23) surgery were randomly assigned with respect to the target value for PaCO2 during cardiopulmonary bypass. In 44 patients the target PaCO2 was 40 mmHg, measured at the standard electrode temperature of 37 degrees C, while in 42...

journal_title：Anesthesiology

authors： Bashein G,Townes BD,Nessly ML,Bledsoe SW,Hornbein TF,Davis KB,Goldstein DE,Coppel DB

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Furosemide and mannitol are used to reduce intracranial pressure, but the impact of furosemide on edema of injured brain is unclear. The authors examined the effects of furosemide and mannitol, alone and in combination, on brain water content in brain-injured rats. METHODS:Anesthetized rats were subjected t...

journal_title：Anesthesiology

authors： Todd MM,Cutkomp J,Brian JE

更新日期：2006-12-01 00:00:00

abstract：:The thermoregulatory threshold for vasoconstriction has been studied in infants and children given isoflurane, but not in those given halothane anesthesia. More importantly, the effect of vasoconstriction on central temperature in pediatric patients remains unknown. Also unknown is the effect of caudal analgesia on va...

journal_title：Anesthesiology

authors： Bissonnette B,Sessler DI

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Only limited data exist comparing differences in sensory function and responses to neural blockade in infant and adult rats. Therefore, the authors sought (1) to compare baseline thermal, proprioceptive, and postural responses in infant, adolescent, and adult rats; and (2) to compare the effects of sciatic n...

journal_title：Anesthesiology

authors： Hu D,Hu R,Berde CB

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Factor VII is the most affected clotting factor during the early phase of warfarin therapy. An international normalized ratio (INR) of more than 1.4 is considered unsafe for epidural catheter placement or removal, according to the American Society of Regional Anesthesia and Pain Medicine. The authors tested ...

journal_title：Anesthesiology

authors： Benzon HT,Avram MJ,Benzon HA,Kirby-Nolan M,Nader A

更新日期：2010-02-01 00:00:00

abstract：:Various animal models have been used for studies of bupivacaine cardiovascular toxicity. These studies are difficult to relate to the clinical situation, since the disposition of bupivacaine in the various species is unknown. The serum protein binding of bupivacaine, therefore, was determined in human, sheep, monkey, ...

journal_title：Anesthesiology

authors： Coyle DE,Denson DD,Thompson GA,Myers JA,Arthur GR,Bridenbaugh PO

更新日期：1984-08-01 00:00:00