Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia.

abstract：:The effects of gamma-aminobutyric acid (GABA) on the induction of convulsions by local anesthetics were investigated in mice and rats. Intraventricular administration of 0.8-1.6 mg GABA protected rats against convulsions induced by procaine, lidocaine, cocaine, and tetracaine in a dose-related manner. Intraperitoneal ...

journal_title：Anesthesiology

authors： Ikeda M,Dohi T,Tsujimoto A

更新日期：1982-05-01 00:00:00

abstract：:The authors hypothesized that relaxation of airway smooth muscle by halothane lessens the dependence of airway resistance on lung volume, and that halothane alters the relationship between pulmonary resistance and lung volume by changing both the airway and tissue components of pulmonary resistance. The relationship a...

journal_title：Anesthesiology

authors： Joyner MJ,Warner DO,Rehder K

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:alpha 2 Agonists are powerful analgesics after spinal delivery. The current work characterizes the dose-dependent antinociception and effects upon respiratory function of dexmedetomidine after intrathecal, epidural, intravenous, and intracisternal delivery in chronically prepared dogs. METHODS:Dogs were pre...

journal_title：Anesthesiology

authors： Sabbe MB,Penning JP,Ozaki GT,Yaksh TL

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Liver damage by ischemia and reperfusion injury is a risk factor for morbidity and mortality after liver surgery. Postoperative oxygen treatment is routinely applied in the postanesthesia and intensive care unit after liver surgery. The risks of aggravating the injury by increasing inspiratory oxygen from 21...

journal_title：Anesthesiology

authors： Zangl Q,Martignoni A,Jackson SH,Ohta A,Klaunberg B,Kaufmann I,Lukashev D,Ward JM,Sitkovsky M,Thiel M,Choukèr A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Nonsteroidal antiinflammatory drugs are commonly used to treat postoperative and chronic pain. Animal studies suggest that these drugs act, in part, by blocking prostaglandin production in the spinal cord. The authors tested intrathecal ketorolac in patients with chronic or postoperative pain. METHODS:After...

journal_title：Anesthesiology

authors： Eisenach JC,Curry R,Rauck R,Pan P,Yaksh TL

更新日期：2010-05-01 00:00:00

abstract：:There has been a dramatic growth of scholarly articles in medical education in recent years. Evaluating medical education research requires specific orientation to issues related to format and content. Our goal is to review the quantitative aspects of research in medical education so that clinicians may understand the...

journal_title：Anesthesiology

authors： Ratelle JT,Sawatsky AP,Beckman TJ

更新日期：2019-07-01 00:00:00

abstract：WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Craniotomy for brain tumor displays significant morbidity and mortality, and no score is available to discriminate high-risk patients. Our objective was to validate a prediction score for postoperative neurosurgical complications...

journal_title：Anesthesiology

authors： Cinotti R,Bruder N,Srairi M,Paugam-Burtz C,Beloeil H,Pottecher J,Geeraerts T,Atthar V,Guéguen A,Triglia T,Josserand J,Vigouroux D,Viquesnel S,Lakhal K,Galliez M,Blanloeil Y,Le Thuaut A,Feuillet F,Rozec B,Asehnoune K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Aqueous suspensions of the local anesthetic n-butyl-p-aminobenzoate (BAB), epidurally applied in terminal cancer patients, resulted in a sensory blockade, lasting up to several months. To investigate the mechanism of action on the cellular level, the effect of 100 microM BAB on Na+ action potentials and on N...

journal_title：Anesthesiology

authors： Van den Berg RJ,Van Soest PF,Wang Z,Grouls RJ,Korsten HH

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Some studies suggest that the orbicularis oculi is resistant to neuromuscular blocking drugs and behaves like laryngeal muscles. Others report little or no difference between the orbicularis oculi and the adductor pollicis. These discrepancies could be related to the exact site of recording. The purpose of t...

journal_title：Anesthesiology

authors： Plaud B,Debaene B,Donati F

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Because the ultimate purpose of new medical knowledge is to achieve improved health outcomes, physicians need to possess and use this knowledge in their practice. The authors introduced enhanced education and individualized feedback to reduce postoperative nausea and vomiting (PONV). The primary objective wa...

journal_title：Anesthesiology

authors： Cohen MM,Rose DK,Yee DA

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Neurocognitive dysfunction is a common complication of cardiac surgery using cardiopulmonary bypass (CPB). Elucidating injury mechanisms and developing neuroprotective strategies have been hampered by the lack of a suitable long-term recovery model of CPB. The purpose of this study was to investigate neurolo...

journal_title：Anesthesiology

authors： Mackensen GB,Sato Y,Nellgård B,Pineda J,Newman MF,Warner DS,Grocott HP

更新日期：2001-12-01 00:00:00

abstract：:Hemodynamic changes during four anesthetic techniques were studied in 80 preterm neonates. Atropine, 0.02 mg/kg, and pancuronium, 0.1 mg/kg, were given intravenously to all patients, who were ventilated with oxygen and air. Each group of 20 patients then received 0.75% isoflurane, 0.5% halothane, 20 micrograms/kg fent...

journal_title：Anesthesiology

authors： Friesen RH,Henry DB

更新日期：1986-02-01 00:00:00

abstract：:The metabolism of alfentanil was studied in three healthy subjects after a 1-h infusion of 2.5 mg alfentanil-3H. One of the subjects was a poor hydroxylator of debrisoquine. Pharmacokinetic parameters were similar in the three subjects and were in the same range as those reported for volunteers. The majority of the ad...

journal_title：Anesthesiology

authors： Meuldermans W,Van Peer A,Hendrickx J,Woestenborghs R,Lauwers W,Heykants J,Vanden Bussche G,Van Craeyvelt H,Van der Aa P

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:The myocardial negative inotropic effects of desflurane are less pronounced than those of other halogenated anesthetics, partly because of intramyocardial catecholamine store release. However, the effects of desflurane on aging myocardium are unknown, whereas aging is known to be associated with an attenuati...

journal_title：Anesthesiology

authors： Rozenberg S,Besse S,Amour J,Vivien B,Tavernier B,Riou B

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Mutations in the ryanodine type 1 receptor (RyR1) are causative for malignant hyperthermia. Studies in human B lymphocytes have shown that measurement of RyR1-mediated intracellular Ca(2+) (Ca(2+)(i)) release can differentiate between normal and malignant hyperthermia-susceptible individuals. The authors hav...

journal_title：Anesthesiology

authors： McKinney LC,Butler T,Mullen SP,Klein MG

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The mechanisms of ventilator-induced lung injury, an iatrogenic inflammatory condition induced by mechanical ventilation, are not completely understood. Toll-like receptor 4 (TLR4) signaling via the adaptor protein myeloid differentiation factor 88 (MyD88) is proinflammatory and plays a critical role in host...

journal_title：Anesthesiology

authors： Li H,Su X,Yan X,Wasserloos K,Chao W,Kaynar AM,Liu ZQ,Leikauf GD,Pitt BR,Zhang LM

更新日期：2010-09-01 00:00:00

abstract：:Critically ill patients often suffer from multiple organ failures involving lung, kidney, liver, or brain. Genomic, proteomic, and metabolomic approaches highlight common injury mechanisms leading to acute organ failure. This underlines the need to focus on therapeutic strategies affecting multiple injury pathways. Th...

journal_title：Anesthesiology

authors： Monsel A,Zhu YG,Gennai S,Hao Q,Liu J,Lee JW

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The current study was designed to test the hypothesis that the fibromyalgia survey criteria would be directly associated with increased opioid consumption after hysterectomy even when accounting for other factors previously described as being predictive for acute postoperative pain. METHODS:Two hundred eigh...

journal_title：Anesthesiology

authors： Janda AM,As-Sanie S,Rajala B,Tsodikov A,Moser SE,Clauw DJ,Brummett CM

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Cardiac complications are common during the postoperative period and may be associated with hypoxemia and tachycardia. Preliminary studies in high-risk patients after operation have shown a possible beneficial effect of oxygen therapy on arterial oxygen saturation and heart rate. METHODS:The authors studied...

journal_title：Anesthesiology

authors： Rosenberg-Adamsen S,Lie C,Bernhard A,Kehlet H,Rosenberg J

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Patients undergoing cardiac surgery employing cardiopulmonary bypass frequently require transfusion of homologous blood products and, therefore, are exposed to the risk of transfusions. Autologous platelet-rich plasma administration may reduce homologous transfusion and attendant risks. METHODS:In a blinded...

journal_title：Anesthesiology

authors： Ereth MH,Oliver WC Jr,Beynen FM,Mullany CJ,Orszulak TA,Santrach PJ,Ilstrup DM,Weaver AL,Williamson KR

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Norepinephrine has been investigated as a potential alterative to phenylephrine for maintaining blood pressure during spinal anesthesia for cesarean delivery with the advantage of less depression of maternal heart rate and cardiac output. However, the relative potencies of these two vasopressors have not bee...

journal_title：Anesthesiology

authors： Ngan Kee WD

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Adding sodium bicarbonate to lidocaine to enhance its efficacy during peripheral nerve block is controversial. The authors studied the effect of adding sodium bicarbonate to lidocaine with and without epinephrine versus equivalent alkalinization by sodium hydroxide (NaOH) on onset, degree, and duration of pe...

journal_title：Anesthesiology

authors： Sinnott CJ,Garfield JM,Thalhammer JG,Strichartz GR

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Moxonidine, a novel imidazoline-alpha2-adrenergic receptor-selective analgesic, was recently identified as antinociceptive but has yet to be evaluated in neuropathic pain models. alpha2-adrenergic receptor-selective analgesics, and high-efficacy opioids, effectively inhibit neuropathic pain behaviors in rode...

journal_title：Anesthesiology

authors： Fairbanks CA,Nguyen HO,Grocholski BM,Wilcox GL

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Acute kidney injury is a common complication after cardiac surgery, leading to increased morbidity and mortality. One suggested cause for acute kidney injury is extracorporeal circulation-induced ischemia-reperfusion injury. In animal studies, cyclosporine has been shown to reduce ischemia-reperfusion injury...

journal_title：Anesthesiology

authors： Ederoth P,Dardashti A,Grins E,Brondén B,Metzsch C,Erdling A,Nozohoor S,Mokhtari A,Hansson MJ,Elmér E,Algotsson L,Jovinge S,Bjursten H

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The dose-dependent myocardial depression of volatile general anesthetics such as isoflurane has been linked to blockade of L-type Ca2+ channels. The effects of (+)- and (-)-isoflurane on the inhibition of [3H]isradipine binding to L-type Ca2+ channels in membranes prepared from mouse heart were examined. In ...

journal_title：Anesthesiology

authors： Moody EJ,Harris B,Hoehner P,Skolnick P

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:The direct action of sevoflurane on systemic resistance arteries is not fully understood. METHODS:Isometric force was recorded in isolated rat small mesenteric arteries. RESULTS:Sevoflurane (2-5%) enhanced contractile response to norepinephrine only in the presence of endothelium, but inhibited it in its a...

journal_title：Anesthesiology

authors： Izumi K,Akata T,Takahashi S

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:The authors compare three techniques for insertion of the ProSeal laryngeal mask airway. METHODS:Two hundred forty healthy patients aged 18-80 yr were randomly allocated for ProSeal laryngeal mask airway insertion using the digital, introducer tool (IT), or gum elastic bougie (GEB)-guided techniques. The di...

journal_title：Anesthesiology

authors： Brimacombe J,Keller C,Judd DV

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Adaptive support ventilation (ASV) allows the clinician to set a maximum plateau pressure (PP) and automatically adjusts tidal volume to keep PP below the set maximum. METHODS:ASV was compared to a fixed tidal volume of 6 ml/kg. ASV determined the respiratory rate and tidal volume based on its algorithms. M...

journal_title：Anesthesiology

authors： Sulemanji D,Marchese A,Garbarini P,Wysocki M,Kacmarek RM

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Blood conservation techniques are being increasingly used because of the increased cost and lack of availability of allogeneic blood. Cell salvage offers great blood savings opportunities but is thought to be contraindicated in a number of areas (e.g., blood contaminated with bacteria). Several outcome studi...

journal_title：Anesthesiology

authors： Waters JH,Tuohy MJ,Hobson DF,Procop G

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:High-fidelity simulation is known to improve participant learning and behavioral performance. Simulation scenarios generate stress that affects memory retention and may impact future performance. The authors hypothesized that more participants would recall three or more critical key messages at three months ...

journal_title：Anesthesiology

authors： Lilot M,Evain JN,Bauer C,Cejka JC,Faure A,Balança B,Vassal O,Payet C,Bui Xuan B,Duclos A,Lehot JJ,Rimmelé T

更新日期：2018-03-01 00:00:00