A Random-allocation Graded Dose-Response Study of Norepinephrine and Phenylephrine for Treating Hypotension during Spinal Anesthesia for Cesarean Delivery.

abstract：BACKGROUND:We describe the anesthetic management for a new surgical procedure: laser ablation of emphysematous bullae via thoracoscope. Although thoracoscopy is not new, this is the first description of a series of patients with bilateral, chronic lung disease who underwent long periods of one-lung ventilation (OLV) du...

journal_title：Anesthesiology

authors： Barker SJ,Clarke C,Trivedi N,Hyatt J,Fynes M,Roessler P

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Previous clinical evidence and electrophysiologic studies in the authors' laboratory have implicated the dorsal column (DC) as an important pathway for the transmission of visceral colorectal pain. This study examined, behaviorally and electrophysiologically, the role of the DC in mediating epigastric nocice...

journal_title：Anesthesiology

authors： Feng Y,Cui M,Al-Chaer ED,Willis WD

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Pulsus alternans is a classic type of abnormal pulse. It can be defined as a regular alternation of pulse amplitude in which runs of weak and strong beats follow each other alternatively without any change in cycle length. It may be a sign of severe decompensated congestive heart failure. The authors infrequ...

journal_title：Anesthesiology

authors： Saghaei M,Mortazavian M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics depress left ventricular contractile function by altering voltage-dependent slow calcium (Ca2+) channel activity in the sarcolemmal membrane. This investigation examined the left ventricular systolic and diastolic mechanical effects of the dihydropyridine Ca2+ channel antagonist nifedipi...

journal_title：Anesthesiology

authors： Pagel PS,Hettrick DA,Warltier DC

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:The neural mechanisms underlying the modulation of pain perception by hypnosis remain obscure. In this study, we used positron emission tomography in 11 healthy volunteers to identify the brain areas in which hypnosis modulates cerebral responses to a noxious stimulus. METHODS:The protocol used a factorial ...

journal_title：Anesthesiology

authors： Faymonville ME,Laureys S,Degueldre C,DelFiore G,Luxen A,Franck G,Lamy M,Maquet P

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Protamine causes multiple adverse reactions. Heparinase I, a specific enzyme that inactivates heparin, is a possible alternative to protamine. In this study, the authors examined the efficacy of heparinase I to reverse heparin-induced anticoagulation in vitro and compared heparinase I to protamine as an anta...

journal_title：Anesthesiology

authors： Michelsen LG,Kikura M,Levy JH,Lee MK,Lee KC,Zimmermann JJ,Szlam F

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:The direct action of sevoflurane on systemic resistance arteries is not fully understood. METHODS:Isometric force was recorded in isolated rat small mesenteric arteries. RESULTS:Sevoflurane (2-5%) enhanced contractile response to norepinephrine only in the presence of endothelium, but inhibited it in its a...

journal_title：Anesthesiology

authors： Izumi K,Akata T,Takahashi S

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Propofol can be associated with delayed awakening after prolonged infusion. The aim of this study was to characterize the preclinical pharmacology of AZD-3043, a positive allosteric modulator of the γ-aminobutyric acid type A (GABA(A)) receptor containing a metabolically labile ester moiety. The authors post...

journal_title：Anesthesiology

authors： Egan TD,Obara S,Jenkins TE,Jaw-Tsai SS,Amagasu S,Cook DR,Steffensen SC,Beattie DT

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Perioperative beta-blockade has been shown to improve long-term cardiac outcome in noncardiac surgical patients. A possible mechanism for the reduced risk of perioperative myocardial infarction is the attenuation of the excitotoxic effects of catecholamine surges by beta-blockade. It was hypothesized that be...

journal_title：Anesthesiology

authors： Zaugg M,Tagliente T,Lucchinetti E,Jacobs E,Krol M,Bodian C,Reich DL,Silverstein JH

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Impaired excitatory and inhibitory balance in the spinal dorsal horn has a crucial role in the pathophysiology of chronic pain. The authors addressed the therapeutic impact of increasing spinal glycine applied exogenously or via blockade of glycine transporter 1 using its selective inhibitors sarcosine and N...

journal_title：Anesthesiology

authors： Tanabe M,Takasu K,Yamaguchi S,Kodama D,Ono H

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Elimination of daily-routine chest radiographs (CXRs) may influence chest computed tomography (CT) and ultrasound practice in critically ill patients. METHODS:This was a retrospective cohort study including all patients admitted to a university-affiliated intensive care unit during two consecutive periods o...

journal_title：Anesthesiology

authors： Kröner A,Binnekade JM,Graat ME,Vroom MB,Stoker J,Spronk PE,Schultz MJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Arginine vasopressin (AVP) is an important "stress" hormone that is known to play a key role in cardiovascular homeostasis of the systemic circulation. In contrast, the effects of AVP on the pulmonary circulation have not been extensively investigated, and the extent to which general anesthesia alters the pu...

journal_title：Anesthesiology

authors： Trempy GA,Nyhan DP,Murray PA

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Spontaneous breaths during airway pressure release ventilation (APRV) have to overcome the resistance of the artificial airway. Automatic tube compensation provides ventilatory assistance by increasing airway pressure during inspiration and lowering airway pressure during expiration, thereby compensating for...

journal_title：Anesthesiology

authors： Wrigge H,Zinserling J,Hering R,Schwalfenberg N,Stüber F,von Spiegel T,Schroeder S,Hedenstierna G,Putensen C

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Prostacyclin (PGI2) is known to be an important mediator of peripheral pain sensation (nociception) whereas little is known about its role in central sensitization. METHODS:The levels of the stable PGI2-metabolite 6-keto-prostaglandin F1α (6-keto-PGF1α) and of prostaglandin E2 (PGE2) were measured in the do...

journal_title：Anesthesiology

authors： Schuh CD,Brenneis C,Zhang DD,Angioni C,Schreiber Y,Ferreiros-Bouzas N,Pierre S,Henke M,Linke B,Nüsing R,Scholich K,Geisslinger G

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Postoperative nausea and vomiting (PONV) is still common, especially among female patients. Our hypothesis is that coinduction with clonidine reduces the incidence of PONV in adult patients undergoing breast cancer surgery. METHODS:Sixty-eight women premedicated with midazolam were randomly allocated to coi...

journal_title：Anesthesiology

authors： Oddby-Muhrbeck E,Eksborg S,Bergendahl HT,Muhrbeck O,Lönnqvist PA

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Previous studies integrated opioid benefit and harm into one single function-the utility function-to determine the drug toxicity (respiratory depression) in light of its wanted effect (analgesia). This study further refined the concept of the utility function using the respiratory and analgesic effects of th...

journal_title：Anesthesiology

authors： Roozekrans M,van der Schrier R,Aarts L,Sarton E,van Velzen M,Niesters M,Dahan A,Olofsen E

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Whether the fetus can experience pain remains controversial. During the last half of pregnancy, the neuroanatomic connections for nociception are in place, and the human fetus mounts sizable stress responses to physical insults. Analgesia has been recommended for intrauterine procedures or late termination, ...

journal_title：Anesthesiology

authors： Fisk NM,Gitau R,Teixeira JM,Giannakoulopoulos X,Cameron AD,Glover VA

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) 130/0.4 may impair blood coagulation less than other HES solutions and, thus, may be used at larger doses without increasing the risk of postoperative bleeding. This study tested the hypothesis that volume replacement with 6% HES 130/0.4 at a dose of up to 50 ml/kg does not increase...

journal_title：Anesthesiology

authors： Kasper SM,Meinert P,Kampe S,Görg C,Geisen C,Mehlhorn U,Diefenbach C

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Caveolae are a nexus for protective signaling. Trafficking of caveolin to mitochondria is essential for adaptation to cellular stress though the trafficking mechanisms remain unknown. The authors hypothesized that G protein-coupled receptor/inhibitory G protein (Gi) activation leads to caveolin trafficking t...

journal_title：Anesthesiology

authors： Wang J,Schilling JM,Niesman IR,Headrick JP,Finley JC,Kwan E,Patel PM,Head BP,Roth DM,Yue Y,Patel HH

更新日期：2014-09-01 00:00:00

abstract：:Transient hyperreflexia, the Babinski reflex, and other transient neurologic signs may follow anesthesia in healthy persons. The authors describe the appearance and durations of these signs and relate them to anesthetic agent, time following cessation of anesthesia, and state of arousal. Twenty-nine neurologically nor...

journal_title：Anesthesiology

authors： Rosenberg H,Clofine R,Bialik O

更新日期：1981-02-01 00:00:00

abstract：:Arterial and peripheral venous plasma levels of bupivacaine were determined in 30 patients following epidural anesthesia using 150 and 225 mg, as well as following intercostal nerve block with 400 mg. Arterial levels were consistently higher than levels in simultaneously sampled venous blood, and the highest levels oc...

journal_title：Anesthesiology

authors： Moore DC,Mather LE,Bridenbaugh PO,Bridenbaugh LD,Balfour RI,Lysons DF,Horton WG

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Suboptimal tissue perfusion and oxygenation during surgery may be responsible for postoperative nausea and vomiting in some patients. This trial tested the hypothesis that muscular tissue oxygen saturation-guided intraoperative care reduces postoperative nausea and vomiting. METHODS:This multicenter, pragma...

journal_title：Anesthesiology

authors： Li G,Tian DD,Wang X,Feng X,Zhang W,Bao J,Wang DX,Ai YQ,Liu Y,Zhang M,Xu M,Mu DL,Zhao X,Dai F,Yang JJ,Che X,Yanez D,Guo X,Meng L,iMODIPONV Research Group.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:A combination of opioid and nonopioid analgesic drugs may improve the quality of postoperative analgesia as well as reduce opioid requirements and their associated side effects. Studies have shown synergism between gabapentin and morphine in animal and human experiments and in the treatment of incisional pai...

journal_title：Anesthesiology

authors： Turan A,Karamanlioğlu B,Memiş D,Hamamcioglu MK,Tükenmez B,Pamukçu Z,Kurt I

更新日期：2004-04-01 00:00:00

abstract：:The treatment of venous air embolism by aspiration from central venous catheters is well established. However, some anesthesiologists prefer to use a pulmonary artery catheter to monitor patients undergoing a neurosurgical procedure in the sitting position. While offering certain advantages, pulmonary artery catheters...

journal_title：Anesthesiology

authors： Bowdle TA,Artru AA

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:The authors developed a measure to determine whether maternal motivation to be present during induction (Motivation for Parental Presence during Induction of Anesthesia [MPPIA]) is related to children's anxiety during the induction process. METHODS:Mothers and children (aged 2-12 yr) undergoing outpatient, ...

journal_title：Anesthesiology

authors： Caldwell-Andrews AA,Kain ZN,Mayes LC,Kerns RD,Ng D

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:In vitro, halothane appears to affect the role played by nitric oxide in the regulation of vascular tone and cardiac function. In vivo, the results of the interactions between halothane and the nitric oxide pathway remain controversial. The authors investigated the effects of halothane on the cardiac and reg...

journal_title：Anesthesiology

authors： Chelly JE,Doursout MF,Lechevalier T,Liang YY,Chelly F,Hartley C,Kilbourn RG

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Previous studies reported that thoracic epidural anesthesia (TEA) protected against a decrease in gastric intramucosal pH, suggesting that TEA increased gut mucosal perfusion. The current study examines the effects of TEA on ileal mucosa using intravital microscopy in anesthetized rats. METHODS:Nineteen rat...

journal_title：Anesthesiology

authors： Sielenkämper AW,Eicker K,Van Aken H

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Patients undergoing cardiac surgery employing cardiopulmonary bypass frequently require transfusion of homologous blood products and, therefore, are exposed to the risk of transfusions. Autologous platelet-rich plasma administration may reduce homologous transfusion and attendant risks. METHODS:In a blinded...

journal_title：Anesthesiology

authors： Ereth MH,Oliver WC Jr,Beynen FM,Mullany CJ,Orszulak TA,Santrach PJ,Ilstrup DM,Weaver AL,Williamson KR

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:During muscular exercise, a negative correlation has been demonstrated between the value of mixed venous oxygen saturation (SvO2) and the level of muscular work, expressed at each level as the ratio of oxygen uptake (VO2) to each subject's maximal oxygen uptake (VO2max). Because the immediate postoperative p...

journal_title：Anesthesiology

authors： Viale JP,Annat G,Lehot JJ,Quard S,Quintin L,Parlow J,Durand PG,Zabot JM,Villard J,Estanove S

更新日期：1994-02-01 00:00:00

abstract：:The authors determined whether they could predict accurately the solubility of anesthetics in aqueous solutions at 37 degrees C, knowing the osmolarity and the pH of the solution and the solute composition. The partition coefficients of the four volatile anesthetics, isoflurane, enflurane, halothane, and methoxyfluran...

journal_title：Anesthesiology

authors： Lerman J,Willis MM,Gregory GA,Eger EI 2nd

更新日期：1983-12-01 00:00:00