Pulmonary vasoregulation by arginine vasopressin in conscious, halothane-anesthetized, and pentobarbital-anesthetized dogs with increased vasomotor tone.

abstract：:Measurement of serum fentanyl and alfentanil concentrations by radioimmunoassay (RIA) may result in significant errors and high variability when the technique described in the available fentanyl and alfentanil RIA kits is used. The authors found a 29-94% overestimation of measured fentanyl and alfentanil serum levels ...

journal_title：Anesthesiology

authors： Schüttler J,White PF

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Despite the fact that obesity is a known risk factor for cardiovascular disease, many studies have failed to demonstrate that obesity is independently associated with an increased risk of cardiovascular morbidity and mortality in nondiabetic patients undergoing coronary artery bypass graft surgery. The autho...

journal_title：Anesthesiology

authors： Pan W,Hindler K,Lee VV,Vaughn WK,Collard CD

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Nitrous oxide limits intraoperative hypothermia because the vasoconstriction threshold with nitrous oxide is higher than with equi-minimum alveolar concentrations of sevoflurane or isoflurane, presumably because of its stimulating actions on the sympathetic nervous system. Xenon, in contrast, does not cause ...

journal_title：Anesthesiology

authors： Goto T,Matsukawa T,Sessler DI,Uezono S,Ishiguro Y,Ozaki M,Morita S

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:: Recent population studies have suggested that children with multiple exposures to anesthesia and surgery at an early age are at an increased risk of cognitive impairment. The authors therefore have established an animal model with single versus multiple exposures of anesthetic(s) in young versus adult mice...

journal_title：Anesthesiology

authors： Shen X,Dong Y,Xu Z,Wang H,Miao C,Soriano SG,Sun D,Baxter MG,Zhang Y,Xie Z

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Up to 84% of women who undergo operative vaginal delivery receive neuraxial analgesia. However, little is known about the association between neuraxial analgesia and neonatal morbidity in women who undergo operative vaginal delivery. The authors hypothesized that neuraxial analgesia is associated with a redu...

journal_title：Anesthesiology

authors： Butwick AJ,Wong CA,Lee HC,Blumenfeld YJ,Guo N

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Some patients develop recrudescence after a malignant hyperthermia (MH) reaction, but it is not clear which patients are at risk. The authors analyzed clinical variables associated with recrudescence after a clinical MH episode. METHODS:Data were obtained from Adverse Metabolic Reaction to Anesthesia report...

journal_title：Anesthesiology

authors： Burkman JM,Posner KL,Domino KB

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Cortical networks generate diverse patterns of rhythmic activity. Theta oscillations (4-12 Hz) are commonly observed during spatial learning and working memory tasks. The authors ask how etomidate, acting predominantly via gamma-aminobutyric acid type A (GABAA) receptors containing beta2 or beta3 subunits, a...

journal_title：Anesthesiology

authors： Drexler B,Roether CL,Jurd R,Rudolph U,Antkowiak B

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:A recent model of acute incisional pain has been characterized that strongly parallels the postoperative period in patients experiencing evoked pain. In that setting, abundant literature has revealed antihypersensitive effects produced by intrathecally administered alpha2-adrenergic receptor agonists, such a...

journal_title：Anesthesiology

authors： Duflo F,Boselli E,Ryvlin P,Chassard D

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Knowledge of normal front teeth-to-carina distance (FT-C) might prevent accidental bronchial intubation. The aim of the current study was to measure FT-C and to examine whether the Morgan formula for oral intubation depth, i.e., endotracheal tube (ETT) position at front teeth (cm) = 0.10 x height (cm) + 5, g...

journal_title：Anesthesiology

authors： Hunyady AI,Pieters B,Johnston TA,Jonmarker C

更新日期：2008-06-01 00:00:00

abstract：:Eighty-six patients undergoing coronary artery bypass graft (n = 63) or intracardiac (n = 23) surgery were randomly assigned with respect to the target value for PaCO2 during cardiopulmonary bypass. In 44 patients the target PaCO2 was 40 mmHg, measured at the standard electrode temperature of 37 degrees C, while in 42...

journal_title：Anesthesiology

authors： Bashein G,Townes BD,Nessly ML,Bledsoe SW,Hornbein TF,Davis KB,Goldstein DE,Coppel DB

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Animal studies have provided considerable evidence to support a role of histamine in the central nervous system in thermoregulation, and premedication with a histamine H2 receptor antagonist before general anesthesia is used to reduce the risk of acid aspiration. The authors investigated whether premedicatio...

journal_title：Anesthesiology

authors： Hirose M,Hara Y,Matsusaki M

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Septic shock is associated with vasopressin deficiency and a hypersensitivity to its exogenous administration. The goal of the current study was to determine whether short-term vasopressin infusion in patients experiencing severe septic shock has a vasopressor sparing effect while maintaining hemodynamic sta...

journal_title：Anesthesiology

authors： Patel BM,Chittock DR,Russell JA,Walley KR

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Nonimmobilizers are agents that lack anesthetic properties, although their chemical structure is very similar to known anesthetics. The primary action site of both agents, whether at the membrane or target protein level, is still a matter of debate. However, increasing evidence points to the distinct modific...

journal_title：Anesthesiology

authors： Koubi L,Tarek M,Bandyopadhyay S,Klein ML,Scharf D

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Rapid elimination of nitrous oxide from the lungs at the end of inhalational anesthesia dilutes alveolar oxygen, producing "diffusion hypoxia." A similar dilutional effect on accompanying volatile anesthetic agent has not been evaluated and may impact the speed of emergence. METHODS:Twenty patients undergoi...

journal_title：Anesthesiology

authors： Peyton PJ,Chao I,Weinberg L,Robinson GJ,Thompson BR

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The rate of administration of an intravenous anesthetic induction agent is an important variable determining the total dose required to reach a given endpoint, such as loss of consciousness (LOC). The influence of infusion rate on the dose-response relationship has not been described rigorously. In this stud...

journal_title：Anesthesiology

authors： Gentry WB,Krejcie TC,Henthorn TK,Shanks CA,Howard KA,Gupta DK,Avram MJ

更新日期：1994-08-01 00:00:00

abstract：:The effects of the neodymium-yttrium aluminum garnet (Nd-YAG) laser on several commonly used endotracheal tubes were examined. Six different types of tubes were tested for flammability. Three tubes were clear, transparent polyvinylchloride with black lettering on the surface. One was yellow-green silicone rubber with ...

journal_title：Anesthesiology

authors： Geffin B,Shapshay SM,Bellack GS,Hobin K,Setzer SE

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:The authors evaluated optimal adrenergic support using norepinephrine, dopamine, and dobutamine in a clinically relevant model of septic shock. METHODS:Twenty-eight mature, female, anesthetized sheep (weight, 30.5 +/- 3.6 kg) underwent cecal ligation and perforation and were randomized into four groups of s...

journal_title：Anesthesiology

authors： Sun Q,Tu Z,Lobo S,Dimopoulos G,Nagy N,Rogiers P,De Backer D,Vincent JL

更新日期：2003-04-01 00:00:00

abstract：:We performed a prospective randomized controlled trial to assess the efficacy of a chlorhexidine dressing in reducing the microbial flora at the insertion site of epidural catheters. These catheters were used for acute pain management and were dressed either by a standardized method or with a CHX/urethane sponge compo...

journal_title：Anesthesiology

authors： Shapiro JM,Bond EL,Garman JK

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Hyperkalemic cardiac arrest after the administration of succinylcholine (SCh) to critically ill intensive care patients has been attributed to changes in the acetylcholine receptors (AChRs) at the muscle membrane. The current study attempts to characterize the contributory roles of chronic administration of ...

journal_title：Anesthesiology

authors： Yanez P,Martyn JA

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Hypotension induced by sodium nitroprusside can minimize intraoperative blood loss. The release of endogenous catecholamines can influence adrenoceptors of platelets and thus might change the ability of platelets to aggregate. METHODS:Forty patients undergoing nasal septum, tympanoplastic, or sphenoid sinus...

journal_title：Anesthesiology

authors： Dietrich GV,Heesen M,Boldt J,Hempelmann G

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Intrathecal methylprednisolone acetate (MPA) has been used in patients with chronic pain syndromes. Its safety has been debated after reports of adverse events. No systematic preclinical evaluation of MPA has been reported. In the current study, the acute and long-term effects of intrathecal MPA on dog spina...

journal_title：Anesthesiology

authors： Rijsdijk M,van Wijck AJ,Kalkman CJ,Meulenhoff PC,Grafe MR,Steinauer J,Yaksh TL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The authors hypothesized that myoclonus after etomidate is dose-related, could be suppressed when small doses of etomidate were administered before induction, and is unassociated with seizure-like activity on electroencephalogram (EEG). METHODS:Three studies were performed. In the first study, 36 men were r...

journal_title：Anesthesiology

authors： Doenicke AW,Roizen MF,Kugler J,Kroll H,Foss J,Ostwald P

更新日期：1999-01-01 00:00:00

abstract：:The solutions to the problems of medical malpractice and malpractice insurance coverage are primarily in the hands of state legislatures. Legislation enacted has been primarily palliative, to assure continued availability of professional liability insurance. Unfortunately, no limit can be placed on the costs of such c...

journal_title：Anesthesiology

authors： Dornette WH

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:It has been known that skeletal muscles show atrophic changes after prolonged sedation or general anesthesia. Whether these effects are due to anesthesia itself or disuse during anesthesia has not been fully clarified. Autophagy dysregulation has been implicated in muscle-wasting conditions. This study teste...

journal_title：Anesthesiology

authors： Kashiwagi A,Hosokawa S,Maeyama Y,Ueki R,Kaneki M,Martyn JA,Yasuhara S

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:In spinal anesthesia, often a large interindividual variability in analgesic response is observed after administration of a certain fixed dose of anesthetic to a patient population. To improve therapeutic outcome it is important to characterize the variability in response by means of a population model (e.g....

journal_title：Anesthesiology

authors： Schnider TW,Minto CF,Bruckert H,Mandema JW

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:There is an unmet clinical need to develop a pharmacological therapy to counter opioid-induced respiratory depression without interfering with analgesia or behavior. Several studies have demonstrated that 5-HT1A receptor agonists alleviate opioid-induced respiratory depression in rodent models. However, ther...

journal_title：Anesthesiology

authors： Ren J,Ding X,Greer JJ

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Although one-lung ventilation (OLV) has become an established procedure during thoracic surgery, sparse data exist about inflammatory alterations in the deflated, reventilated lung. The aim of this study was to prospectively investigate the effect of OLV on the pulmonary inflammatory response and to assess p...

journal_title：Anesthesiology

authors： De Conno E,Steurer MP,Wittlinger M,Zalunardo MP,Weder W,Schneiter D,Schimmer RC,Klaghofer R,Neff TA,Schmid ER,Spahn DR,Z'graggen BR,Urner M,Beck-Schimmer B

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Intraspinally administered alpha 2-adrenergic agonists may relieve pain in sympathetically maintained pain (SMP) syndromes, such as reflex sympathetically dystrophy (RSD), by spinal, peripheral, and central nervous system actions. This study examined analgesic efficacy and side effects of epidurally administ...

journal_title：Anesthesiology

authors： Rauck RL,Eisenach JC,Jackson K,Young LD,Southern J

更新日期：1993-12-01 00:00:00

abstract：:Binding of thiopental to proteins in plasma from healthy, cirrhotic, and uremic subjects was studied using equilibrium dialysis. In plasma from healthy volunteers 28.0 plus or minus 0.9 per cent of thiopental was unbound. In plasma from patients with hepatic disease 53.0 plus or minus 2.1 per cent was unbound, while i...

journal_title：Anesthesiology

authors： Ghoneim MM,Pandya H

更新日期：1975-05-01 00:00:00

abstract：:The effect of physostigmine on the loss of consciousness and respiratory depression induced in rabbits by flunitrazepam, 1 mg/kg, was studied to demonstrate whether the restoration of consciousness and respiration rate results from an increase in central cholinergic activity or from an interference by physostigmine wi...

journal_title：Anesthesiology

authors： Vatashsky E,Beilin B,Razin M,Weinstock M

更新日期：1986-02-01 00:00:00