Post-Extubation Inhaled Nitric Oxide Therapy via High-Flow Nasal Cannula After Fontan Procedure.

Abstract:

:In 2014, our hospital introduced inhaled nitric oxide (iNO) therapy combined with high-flow nasal cannula (HFNC) oxygen therapy after extubation following the Fontan procedure in patients with unstable hemodynamics. We report the benefits of HFNC-iNO therapy in these patients. This was a single-center, retrospective review of 38 patients who underwent the Fontan procedure between January 2010 and June 2016, and required iNO therapy before extubation. The patients were divided into two groups: patients in Epoch 1 (n = 24) were treated between January 2010 and December 2013, receiving only iNO therapy; patients in Epoch 2 (n = 14) were treated between January 2014 and June 2016, receiving iNO therapy and additional HFNC-iNO therapy after extubation. There were no significant differences between Epoch 1 and 2 regarding preoperative cardiac function, age at surgery, body weight, initial diagnosis (hypoplastic left heart syndrome, 4 vs. 2; total anomalous pulmonary venous return, 5 vs. 4; heterotaxy, 7 vs. 8), intraoperative fluid balance, or central venous pressure upon admission to the intensive care unit. Epoch 2 had a significantly shorter duration of postoperative intubation [7.2 (3.7-49) vs. 3.5 (3.0-4.6) hours, p = 0.033], pleural drainage [23 (13-34) vs. 9.5 (8.3-18) days, p = 0.007], and postoperative hospitalization [36 (29-49) vs. 27 (22-36) days, p = 0.017]. Two patients in Epoch 1 (8.3%), but none in Epoch 2, required re-intubation. Our results suggest that HFNC-iNO therapy reduces the duration of postoperative intubation, pleural drainage, and hospitalization.

journal_name

Pediatr Cardiol

journal_title

Pediatric cardiology

authors

Tominaga Y,Iwai S,Yamauchi S,Kyogoku M,Kugo Y,Hasegawa M,Kayatani F,Takahashi K,Aoki H,Takeuchi M,Tachibana K,Kawata H

doi

10.1007/s00246-019-02122-2

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

1064-1071

issue

5

eissn

0172-0643

issn

1432-1971

pii

10.1007/s00246-019-02122-2

journal_volume

40

pub_type

杂志文章
  • Congenital giant aneurysm of the left innominate vein: is surgical treatment required?

    abstract::Congenital aneurysms of the thoracic venous system are rare. In particular, innominate venous aneurysms are extremely rare. We describe a 16-year-old girl whose chest x-ray suggested a mediastinal tumor. Three-dimensional contrast-enhancement magnetic resonance venography showed a giant sacciform aneurysm of the left ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-003-0499-y

    authors: Tsuji A,Katada Y,Tanimoto M,Fujita I

    更新日期:2004-07-01 00:00:00

  • Multicenter Off-Label Use of Nit-Occlud Coil in Retrograde Closure of Small Patent Ductus Arteriosus.

    abstract::We studied the safety and efficacy of closing patent ductus arteriosus by Nit-Occlud coils via retrograde approach. This is a retrospective study of 46 attempts to close ducts by this method in two hospitals in Egypt and Iran. Ductus arteriosus was crossed by left or right Judkins or endhole catheters. The coil was de...

    journal_title:Pediatric cardiology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/s00246-017-1589-6

    authors: Zanjani KS,Sobhy R,El-Kaffas R,El-Sisi A

    更新日期:2017-04-01 00:00:00

  • Successful management of the persistent pulmonary hypertension of the newborn with transposition of the great arteries by restricted patency of the ductus arteriosus: a simple and rational novel strategy.

    abstract::Persistent pulmonary hypertension of the newborn (PPHN) complicated with transposition of the great arteries (TGA) and an intact ventricular septum (IVS) often is therapy resistant and associated with an extremely poor prognosis. For this condition, opening of the ductus arteriosus (DA) by prostaglandin-E1 in conjunct...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-009-9475-5

    authors: Masutani S,Seki M,Taketazu M,Senzaki H

    更新日期:2009-10-01 00:00:00

  • Intrauterine closure of membranous ventricular septal defects: mechanism of closure in two autopsy specimens.

    abstract::Anatomic evidence of intrauterine closure of ventricular septal defects (VSDs) has been reported rarely. Between 1985 and 1990, 112 autopsies were performed at the Mayo Clinic on third trimester stillborns and infants who died during the first week of life. There were 21 (19%) cases of congenital heart disease. VSD wa...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/BF00797004

    authors: Nir A,Driscoll DJ,Edwards WD

    更新日期:1994-01-01 00:00:00

  • Epicardial Pacemaker in Neonates and Infants: Is There a Relationship Between Patient Size, Device Size, and Wound Complicatıon?

    abstract::We aimed to investigate the complications after epicardial pacemaker (PM) implantation in neonates and infants and their relationship with factors such as device size and patient size. Between May 2010 and July 2018, 55 patients under 1 year of age who underwent epicardial PM placement were retrospectively evaluated. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-020-02306-1

    authors: Ergün S,Kafalı HC,Genç SB,Yildiz O,Güneş M,Onan İS,Ergül Y,Güzeltaş A,Haydin S

    更新日期:2020-04-01 00:00:00

  • Echocardiographic evaluation of systolic and diastolic function in postoperative coarctation patients.

    abstract::Postoperative coarctation (CoA) patients are often found to have signs of persistent myocardial dysfunction. M-mode echocardiography was performed to study left ventricular (LV) size, mass, and systolic function and Doppler ultrasonography to study LV filling and flow velocity in the LV outflow tract and aorta in 28 "...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s002469900124

    authors: Sigurdardóttir LY,Helgason H

    更新日期:1997-03-01 00:00:00

  • Assessing ST Segment Changes and Ischemia During Exercise Stress Testing in Patients with Hypoplastic Left Heart Syndrome and Fontan Palliation.

    abstract::While exercise stress testing (EST) is an important tool, little is known about its use for determining ischemia in patients with hypoplastic left heart syndrome (HLHS) and Fontan palliation. We sought to determine the frequency of ST segment changes during EST in HLHS patients after Fontan and examine results of furt...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-015-1312-4

    authors: Kyle WB,Denfield SW,Valdes SO,Penny DJ,Bolin EH,Lopez KN

    更新日期:2016-03-01 00:00:00

  • Improved prenatal detection of congenital heart disease in an integrated health care system.

    abstract::The reported prenatal detection rates (PDRs) for significant congenital heart disease (sCHD) have been suboptimal, even in the current era. Changes in prenatal ultrasound policy and training may lead to improved prenatal detection of sCHD. This study analyzed the results of a policy to assess fetal cardiac outflow tra...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-012-0526-y

    authors: Levy DJ,Pretorius DH,Rothman A,Gonzales M,Rao C,Nunes ME,Bendelstein J,Mehalek K,Thomas A,Nehlsen C,Ehr J,Burchette RJ,Sklansky MS

    更新日期:2013-03-01 00:00:00

  • Nitric oxide in the evaluation of congenital heart disease with pulmonary hypertension: factors related to nitric oxide response.

    abstract::Inhaled nitric oxide (NO) has been used in the preoperative evaluation of patients with congenital heart disease and pulmonary hypertension. The purpose of this study was to characterize responses in pulmonary vascular resistance (PVR) to oxygen and increasing doses of NO during cardiac catheterization and to determin...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-004-0767-5

    authors: Cannon BC,Feltes TF,Fraley JK,Grifka RG,Riddle EM,Kovalchin JP

    更新日期:2005-09-01 00:00:00

  • Transcatheter Intervention for Treatment of Coronary Stenosis After Unroofing of the Anomalous Left Coronary Artery.

    abstract::Anomalous origin of left coronary artery (LCA) from the right coronary cusp with an intramural course is usually managed with unroofing of the intramural segment. Available literature demonstrates an uneventful course following surgery in most patients. Coronary stenosis following the unroofing procedure treated with ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-018-2005-6

    authors: Chakraborty A,Mendoza C,Infante J,Sandhu SK

    更新日期:2019-01-01 00:00:00

  • A case of renal artery stenosis in a child confirmed by multidetector computed tomographic angiography.

    abstract::Renovascular hypertension is an uncommon disease, but it causes 5-10% of all childhood hypertension. The most common cause of renal artery stenosis is fibromuscular dysplasia, resulting in at least 60% of renovascular hypertension cases. This report describes a case of a renal artery stenosis confirmed by multidetecto...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-011-9944-5

    authors: Kim HJ,Son JS,Kim KS

    更新日期:2011-06-01 00:00:00

  • Quantification of congenital aortic valve stenosis in pediatric patients: comparison between cardiac magnetic resonance imaging and transthoracic echocardiography.

    abstract::Previous studies showed the reliability of cardiac magnetic resonance imaging (cMRI) in the quantification of aortic valve stenosis in adults. The aim of this retrospective study was to assess the ability of cMRI in the quantification of congenital aortic valve stenosis (CAS) in children. Nineteen patients (mean age 1...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-013-0851-9

    authors: Sirin S,Nassenstein K,Neudorf U,Jensen CJ,Mikat C,Schlosser T

    更新日期:2014-06-01 00:00:00

  • Positron emission tomography myocardial perfusion imaging in children with suspected coronary abnormalities.

    abstract::Positron emission tomography (PET) myocardial perfusion imaging has higher spatial resolution than conventional single photon emission computed tomography (SPECT) imaging and allows accurate and reproducible quantification of myocardial blood flow (MBF). In this article, we describe the role of PET myocardial perfusio...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-002-0282-5

    authors: Singh TP,Muzik O,Forbes TF,Di Carli MF

    更新日期:2003-03-01 00:00:00

  • Accessory pathway ablation in a 6-year-old girl using remote magnetic navigation as an alternative to cryoablation.

    abstract::A 6-year-old girl with evidence of a parahisian accessory pathway on a baseline electrocardiogram underwent successful catheter ablation using magnetic navigation. Magnetic remote controlled ablation eliminated the parahisian pathway with the first radiofrequency application. A second anterolaterally located concealed...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-012-0540-0

    authors: Mantziari L,Rigby M,Till J,Ernst S

    更新日期:2013-03-01 00:00:00

  • Transposition of Great Arteries with Complex Coronary Artery Variants: Time-Related Events Following Arterial Switch Operation.

    abstract::Coronary artery anatomy represents a challenging and, often, determining predictor of outcome in an arterial switch operation (ASO). Impact of specific coronary artery variants, such as single, intramural and inverted, on time-related events following ASO, is, yet, to be determined. We sought to compare early and late...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-016-1543-z

    authors: Al Anani S,Fughhi I,Taqatqa A,Elzein C,Ilbawi MN,Polimenakos AC

    更新日期:2017-03-01 00:00:00

  • Diagnostic and Prognostic Value of Plasma Levels of Cardiac Myosin Binding Protein-C as a Novel Biomarker in Heart Failure.

    abstract::Heart failure (HF) has high morbidity and mortality in children. This study aimed to investigate the value of cardiac myosin binding protein-C (cMyBP-C) as a diagnostic and prognostic biomarker in children with heart failure. This study was a prospective case-control study that involved 50 children with acute HF and 2...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-016-1532-2

    authors: El Amrousy D,Hodeib H,Suliman G,Hablas N,Salama ER,Esam A

    更新日期:2017-02-01 00:00:00

  • Use of dexmedetomidine in patients with trisomy 21 after cardiac surgery.

    abstract::Children with trisomy 21 have a high incidence of congenital heart disease that frequently requires surgical repair. These patients often require multiple and higher dosage sedatives during the postoperative period. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist that has sedative, analgesic, and anxiolytic...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-006-0072-6

    authors: Kalyanaraman M,Costello JL,Starr JP

    更新日期:2007-09-01 00:00:00

  • Can Abbreviated Cardiac Magnetic Resonance Imaging Adequately Support Clinical Decision Making After Repair of Tetralogy of Fallot?

    abstract::Quantification of pulmonary regurgitation (PR), pulmonary flow distribution, and ventricular function is important for clinical surveillance in repaired Tetralogy of Fallot (TOF). Cardiovascular magnetic resonance (CMR) is the established reference, but cost, test duration, and patient discomfort are potential limitat...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-018-2035-0

    authors: House AV,Muthurangu V,Spanel AJ,Danford DA,Mir B,Schuster A,Hsu H,Kutty S

    更新日期:2019-03-01 00:00:00

  • A multicenter, long-term study on arrhythmias in children with Ebstein anomaly.

    abstract::To assess the prevalence, history, and treatment of arrhythmias, in particular preexcitation and Wolff-Parkinson-White (WPW) syndrome, in patients with Ebstein anomaly (EA) during childhood and adolescence, we performed a multicenter retrospective study of all consecutive live-born patients with EA, diagnosed, and fol...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00246-009-9590-3

    authors: Delhaas T,Sarvaas GJ,Rijlaarsdam ME,Strengers JL,Eveleigh RM,Poulino SE,de Korte CL,Kapusta L

    更新日期:2010-02-01 00:00:00

  • Temporary atrial pacing for cardiac output after pediatric cardiac surgery.

    abstract::Pediatric cardiothoracic surgery is often associated with low cardiac output in the postoperative period. This study sought to determine whether increasing heart rate via temporary atrial pacing is beneficial in augmenting cardiac output. Patients younger than 18 years who underwent cardiothoracic surgery and had no p...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-013-0687-3

    authors: Barker GM,Affolter J,Saenz J,Cox CS,Forbess JM,Scott WA,Zeltser I

    更新日期:2013-10-01 00:00:00

  • Echocardiographic abnormalities in familial dysautonomia.

    abstract::Sudden death accounts for up to 43% of all deaths in patients with familial dysautonomia (FD). The classic features of FD, namely, autonomic dysfunction, high blood pressure, and blood pressure labiality, are all risk factors for cardiac remodeling and hypertrophy. Myocardial remodeling and hypertrophy are independent...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-009-9497-z

    authors: Nussinovitch U,Katz U,Nussinovitch M,Blieden L,Nussinovitch N

    更新日期:2009-11-01 00:00:00

  • Late pulmonary venous obstruction after surgical repair of infradiaphragmatic total anomalous pulmonary venous return.

    abstract::Twelve years after an apparently successful surgical correction of infradiaphragmatic (obstructed) total anomalous pulmonary venous drainage, a 12-year-old boy developed evidence of pulmonary artery hypertension secondary to pulmonary venous obstruction due to an apparent lack of growth at the anastomotic site. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/BF02080561

    authors: Kveselis DA,Chameides L,Diana DJ,Ellison L,Rowland T

    更新日期:1988-01-01 00:00:00

  • Post-Mustard procedure pulmonary venous obstruction: An opportunity for anatomic correction with a one-stage arterial switch.

    abstract::A 14-year-old boy after a Mustard procedure for transposition of the great arteries developed pulmonary hypertension secondary to baffle obstruction. This occurred over several years without apparent significant symptomatology. Systemic-level pressure prevailed in the left (pulmonary) ventricle and provided an opportu...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s002469900470

    authors: Reisman M,Rosengart RM,Degner TL,Sintek C,Khonsari S

    更新日期:1999-07-01 00:00:00

  • Myocardial perfusion abnormalities in patients occurring more than 1 year after successful univentricular (Fontan surgery) and biventricular repair (complete repair of tetralogy of Fallot).

    abstract::The outcome of children born with cyanotic congenital heart disease has markedly improved over the years. Follow up is recommended for most post-operated cases as complications may occur over long term. One of the complications is the development of ventricular dysfunction, often seen after a successful Fontan surgery...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-012-0531-1

    authors: Priyadarshini A,Saxena A,Patel C,Paul VK,Lodha R,Airan B

    更新日期:2013-04-01 00:00:00

  • Hemodynamic assessment in patients with one-and-a-half ventricle repair revealed by four-dimensional flow magnetic resonance imaging.

    abstract::We report hemodynamic findings in two patients with pulmonary atresia and intact ventricular septum (PAIVS) after "one-and-a-half ventricle repair" and placement of a bidirectional Glenn shunt using four-dimensional (4D) flow magnetic resonance imaging. Quantification of flow and analysis of flow patterns revealed the...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-012-0288-6

    authors: Uribe S,Bächler P,Valverde I,Crelier GR,Beerbaum P,Tejos C,Irarrazaval P

    更新日期:2013-02-01 00:00:00

  • Dilated cardiomyopathy masquerading as long QT syndrome.

    abstract::Atrioventricular block has been described in association with cases of long QT syndrome and mortality is increased in this subgroup. We describe an infant with congenital QT prolongation and atrioventricular block with normal cardiac function, leading to the initial diagnosis of long QT syndrome. She subsequently deve...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-005-1114-1

    authors: Walls J,Dipchand A,Sanatani S

    更新日期:2006-01-01 00:00:00

  • Aortic valvar atresia, interrupted aortic arch, and quadricuspid pulmonary valve: a rare combination.

    abstract::Aortic atresia and interrupted aortic arch is a rare cardiac combination. Review of the literature revealed nine cases. We present two patients with this combination and the additional finding of quadricuspid pulmonary valves, one of which was severely stenotic. In the latter patient, an aortopulmonary window was pres...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-004-0754-x

    authors: Yew G,Coleman D,Calder L

    更新日期:2005-07-01 00:00:00

  • Fetal Echocardiographic Dimension Indices: Important Predictors of Postnatal Coarctation.

    abstract::The aim of the study is to identify reliable quantitative fetal echocardiographic predictors for postnatal development of coarctation (CoA). In this retrospective study, we included 65 fetuses with a prenatally suspected, isolated CoA, born 2010-2018. Dimensions of the cardiac structures, aortic, and ductal arches exp...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-020-02509-6

    authors: Fricke K,Liuba P,Weismann CG

    更新日期:2020-12-23 00:00:00

  • Aortopulmonary window coexisting with tetralogy of Fallot: echocardiographic diagnosis.

    abstract::Aortopulmonary window coexisting with tetralogy of Fallot (TF) was prospectively diagnosed by two-dimensional (2D) echocardiography and Doppler in an 18-month-old boy; the diagnosis was confirmed by cardiac catheterization and angiocardiography. Surgical correction was performed, but the patient died in the operating ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/BF02239546

    authors: Carminati M,Borghi A,Valsecchi O,Quattrociocchi M,Balduzzi A,Rusconi P,Russo MG,Festa P,Preda L,Tiraboschi R

    更新日期:1990-01-01 00:00:00

  • Isolated left-ventricular apical hypoplasia presenting as a left-ventricular mass on echocardiography.

    abstract::Left-ventricular apical hypoplasia is a rare entity. Although it has typical imaging features on cardiovascular magnetic resonance, recognizing this condition on echocardiography can be challenging. This report describes an asymptomatic pediatric patient who initially presented with a left-ventricular mass on echocard...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章

    doi:10.1007/s00246-012-0349-x

    authors: Ong CC,Hia CP,Lim TC,Teo LL

    更新日期:2012-12-01 00:00:00