Abstract:
:Postoperative coarctation (CoA) patients are often found to have signs of persistent myocardial dysfunction. M-mode echocardiography was performed to study left ventricular (LV) size, mass, and systolic function and Doppler ultrasonography to study LV filling and flow velocity in the LV outflow tract and aorta in 28 "healthy" postoperative CoA patients (5-21 years) and 28 age- and sex-matched controls. The early (E) and late (A) diastolic transmitral velocities were significantly higher in the patient group than in the controls (p < 0.05). Other diastolic parameters (isovolumic relaxation time, E/A ratio, and deceleration time of the early diastolic velocity) were similar in the two groups (p = NS). The left atrial diameter, LV wall average, end-diastolic diameter of the LV and LV mass were higher in the patients than controls (p < 0.05). The patients also had a higher stroke volume, cardiac output, and cardiac index than the controls (p < 0.01). The fractional shortening was similar in the two groups (p = NS). Blood flow velocities in both the LV outflow tract and aorta were higher in the patients than the controls (p < 0.0002). We found LV hypertrophy with signs of a hyperdynamic circulation (increased cardiac index and stroke volume) in our patients. An increase in A is associated with LV hypertrophy and seems to be a sensitive marker of diastolic abnormality. The rise in E is paradoxical but has been seen in other studies. The increased blood flow velocity in the LV outflow tract suggests obstruction to LV outflow and increased flow in the descending aorta is due to residual coarctation.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Sigurdardóttir LY,Helgason Hdoi
10.1007/s002469900124subject
Has Abstractpub_date
1997-03-01 00:00:00pages
96-100issue
2eissn
0172-0643issn
1432-1971journal_volume
18pub_type
杂志文章abstract::A reduced exercise capacity is a common finding in adult congenital heart disease and is associated with cardiovascular morbidity and mortality. However, data on exercise capacity in patients after repair of coarctation of the aorta (CoA) are scarce. Furthermore, a high rate of exercise-induced hypertension has been d...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02173-5
更新日期:2019-10-01 00:00:00
abstract::Changes in ventricular geometry are often seen in patients with right ventricular hypertension secondary to pulmonary hypertension (PH). Progressive systolic bowing of the inter-ventricular septum occurs with increasing right ventricular pressure (RVp) and can be quantified with the left ventricular end-systolic eccen...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-015-1317-z
更新日期:2016-03-01 00:00:00
abstract::A 5-year-old child with a Fontan circulation presented with acquired left pulmonary vein occlusion related to a previous surgical repair. We managed this lesion using a hybrid technique to perforate, dilate and stent the obstructed vessel. This approach should be considered when percutaneous access to the pulmonary ve...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-016-1376-9
更新日期:2016-06-01 00:00:00
abstract::There is a higher incidence of sudden death in patients with Rett syndrome than individuals in the general population. Previous studies have implicated cardiac dysautonomia and a long QT interval as causative factors. Because carnitine plays a critical role in cellular metabolism and may have beneficial effects on car...
journal_title:Pediatric cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00246-005-0784-z
更新日期:2005-09-01 00:00:00
abstract::Two patients (one girl, one boy) with Kartagener syndrome (situs inversus, bronchiectasis, sinusitis), despite pulmonary problems and associated congenital cardiac anomalies, were operated on at the ages of 4 years and 7 years, respectively. They had had previous palliative treatment at the age of 3 months and 1.3 yea...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900115
更新日期:1997-01-01 00:00:00
abstract::A varying degree of impairment of ventricular performance is observed over the long-term after surgery for a congenital heart defect (CHD). Impaired ventricular performance has been shown to be of prognostic value for increased risk of cardiovascular events in adult CHD patients. This emphasizes the importance of deli...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-013-0802-5
更新日期:2014-01-01 00:00:00
abstract::Dilated cardiomyopathy (DCM) is an important cause of chronic congestive cardiac failure in children. In patients with idiopathic DCM, endothelium vasomotor function is disturbed. There are many studies on the roles of nitric oxide (NO) and adrenomedullin (AM) in adult patients with DCM. However, to our knowledge, no ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-002-0352-8
更新日期:2003-07-01 00:00:00
abstract::Cardiovascular disease is a leading cause of mortality among patients with diabetes, and heart failure exists even in the absence of coronary disease. Myocardial metabolism is altered in the diabetic heart as a result of changes in substrate availability secondary to insulin resistance. The nuclear receptor peroxisome...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-011-9889-8
更新日期:2011-03-01 00:00:00
abstract::The objective of this study was to compare histopathological changes in hypoplastic left heart syndrome right ventricles (RV) of patients undergoing Sano and modified Blalock-Taussig (MBT) shunt and correlate them with echocardiographic findings. Myocardial tissue samples were obtained from hearts with Sano or MBT shu...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0462-x
更新日期:2013-02-01 00:00:00
abstract::Adrenomedullin (ADM) is a vasoactive peptide with potent dilatory effects. We studied whether perioperative myocardial injury could be altered by the presence of ADM. Blood samples from 19 children with congenital heart disease undergoing surgical repair were collected at six time points: preoperative, on cardiopulmon...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002460010046
更新日期:2000-05-01 00:00:00
abstract::Management of warfarin in pediatric patients remains a clinical challenge. Warfarin may be administered after congenital heart surgery, and the risks of morbidity can be high. Currently, no data exist to describe the initiation of warfarin and the risk factors for morbidity in post-congenital heart surgery patients. T...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0351-3
更新日期:2012-12-01 00:00:00
abstract::This study identified tracheobronchial cartilage calcification in children with congenital heart disease. Calcification of the tracheobronchial airways has been found previously in adults receiving warfarin and in children receiving warfarin after mitral valve replacement. A 9-year-old girl who had received a Fontan r...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-014-0880-z
更新日期:2014-08-01 00:00:00
abstract::A primary rhabdomyosarcoma of the heart observed in a 3-week-old infant, provides an opportunity to review this rare clinical entity; 61 reported cases are collated. The more common sites are right ventricle, left atrium, and right atrium; the tumour may protrude into the cavity and cause obstruction. Echocardiography...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02265621
更新日期:1982-01-01 00:00:00
abstract::Twelve years after an apparently successful surgical correction of infradiaphragmatic (obstructed) total anomalous pulmonary venous drainage, a 12-year-old boy developed evidence of pulmonary artery hypertension secondary to pulmonary venous obstruction due to an apparent lack of growth at the anastomotic site. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02080561
更新日期:1988-01-01 00:00:00
abstract::We describe the first report of an infant who was born with hypoplastic left heart syndrome and significant pulmonary stenosis. He was successfully palliated with multiple cardiac catheterization interventions while waiting for cardiac transplantation. This unusual constellation of heart defects is an entity that is r...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-004-0856-5
更新日期:2005-09-01 00:00:00
abstract::A hemodynamically stable neonate with transposition of the great arteries suddenly went into cardiac arrest during preparation for transport to the operating room. Emergency echocardiography during cardiac massage detected coronary air embolism as the presumed cause of arrest. After about 15 minutes of resuscitation, ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-0088-4
更新日期:2011-12-01 00:00:00
abstract::Neo-aortic arch obstruction (NAAO) is a common complication following the Norwood/Sano procedure (NP) for hypoplastic left heart syndrome (HLHS) and is associated with increased morbidity and mortality. However, there is currently no objective method for predicting which patients will develop NAAO. This study was desi...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0713-5
更新日期:2013-01-01 00:00:00
abstract::Recurrent congestive heart failure (CHF) attributable to myocarditis is a seldom-discussed entity in the scientific literature. This report describes the case of an 8-year-old girl who had three clinically identical episodes of CHF, beginning at the age of 5 years, with each episode preceded by a viral prodrome. The c...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-0109-3
更新日期:2012-01-01 00:00:00
abstract::A premature child with congenital complete heart block had an epicardial single-chamber pacemaker implanted at 2 days of age. At 21 months of age, while sitting or standing, the patient's right anterior thigh muscles contracted at her pulse rate. Surgical exploration revealed a free-floating pacemaker in her peritoneu...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900430
更新日期:1999-03-01 00:00:00
abstract::Once a mainstay in the treatment of neonates with d-transposition of the great arteries (d-TGA), the application of balloon atrial septostomy (BAS) in the d-TGA population has become more selective. Currently, there is no clear evidence for or against a selective BAS strategy. The aims of this single-center retrospect...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02520-x
更新日期:2021-01-25 00:00:00
abstract::Ventricular dysfunction in patients after Fontan-like operations (FLOs) is a serious complication that might contribute to poor long-term results. Ischemic heart disease will have debilitating consequences on a Fontan heart. Ten patients (15.8 +/- 5.01 years) after FLO had transesophageal echocardiography and cardiac ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-002-0355-5
更新日期:2003-07-01 00:00:00
abstract::Patency of the ductus arteriosus (PDA) is a common finding in small premature infants. Recently pulsed-Doppler-cross sectional echocardiography (PD-CSE) has been successfully used in these patients. We report a case of a premature infant with an unusual PD-CSE pattern. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02279882
更新日期:1988-01-01 00:00:00
abstract::Ectopic atrial tachycardia (EAT) is often resistant to medical therapy, with radiofrequency ablation (RFA) being a preferred treatment option. Three-dimensional (3-D) electroanatomic mapping was introduced as a tool for improved substrate localization, although there are no published data with this technology in pedia...
journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00246-007-9137-4
更新日期:2008-03-01 00:00:00
abstract::The outcome in a series of 23 cases of tetralogy of Fallot diagnosed prenatally was compared to published figures for this condition when (a) identified postnatally or (b) treated surgically. There was a marked difference in the survival between these groups, with the highest mortality (75%) occurring when the diagnos...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00788220
更新日期:1992-01-01 00:00:00
abstract::Left atrial tumor, diagnosed as myxoma at first investigation, was later demonstrated to be a malignant fibrosarcoma with myxoid change. Myxoma should be diagnosed and managed carefully because of its wide range of histopathologic features. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002460010218
更新日期:2001-05-01 00:00:00
abstract::Requiring bilateral superior cavopulmonary anastomosis (bSCPA) instead of unilateral superior cavopulmonary anastomosis (uSCPA) could influence surgical timing and outcomes. We compared surgical timing and outcomes for patients who underwent uSCPA to those who underwent bSCPA through use of the Pediatric Heart Network...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02527-4
更新日期:2021-01-08 00:00:00
abstract::It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included ...
journal_title:Pediatric cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00246-017-1579-8
更新日期:2017-06-01 00:00:00
abstract::Restrictive cardiomyopathy (RCM) is characterized by irreversible diastolic dysfunction with preserved systolic function. The aim of this study was to investigate the presence of impaired ventricular contractility even in the presence of normal ejection fraction (EF) in children with RCM. Longitudinal Doppler tissue v...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-011-9948-1
更新日期:2011-06-01 00:00:00
abstract::Noninvasive Doppler-derived cardiac output was measured with the pulsed Doppler method in 22 healthy newborns during their first four days of life. Maximal blood flow velocity in the aorta was measured with the Doppler ultrasound method. The mean Doppler-derived cardiac output was 273 +/- 59 ml/min/kg. Ductal left-to-...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02083704
更新日期:1988-01-01 00:00:00
abstract::Various echocardiographic parameters are determined in the assessment and evaluation of a patent ductus arteriosus. In isolation, many of these parameters have a low sensitivity and specificity for ductal hemodynamic significance compared with ductal size. This study aimed to correlate various echocardiographic parame...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0640-5
更新日期:2013-06-01 00:00:00