Abstract:
:Quantification of pulmonary regurgitation (PR), pulmonary flow distribution, and ventricular function is important for clinical surveillance in repaired Tetralogy of Fallot (TOF). Cardiovascular magnetic resonance (CMR) is the established reference, but cost, test duration, and patient discomfort are potential limitations to its serial use. We investigated whether an Abbreviated CMR protocol would alter clinical decisions in TOF from those that would have been made using a full protocol. Patients > 7 years with repaired TOF were identified. CMR was performed according to standard complete imaging protocol. CMRs were prepared in two ways, Full and Abbreviated and submitted for review by two imaging specialists. In conjunction with clinical information and case-specific quantitative CMR data (PR fraction, ventricular volumes, ejection fraction, branch pulmonary artery flow), Full and Abbreviated image sets were anonymized and uploaded for review. For the first half, Imager 1 received Abbreviated, and Imager 2 Full and for the remaining, Imager 1 received Full and Imager 2 received Abbreviated. Blinded to the other's choices, Imagers provided clinical decisions. Inter-rater agreement for each decision was measured. In all, 124 studies from 80 patients (mean 17.8 years) were analyzed. For 'intervention versus no-intervention' decision, the inter-rater agreement was strong [κ 0.75, p < 0.0001, 95% CI (0.630, 0.869)]. Agreement for recommended timing of follow-up imaging was good (κ 0.64, p < 0.0001, 95% CI (0.474, 0.811)] in the 'no-intervention' group. When raters were asked whether or not further imaging was necessary, agreement was modest [κ 0.363 (p < 0.0001), 95% CI (0.038, 0.687)]. In conclusion, Abbreviated CMR yield decisions for clinical care similar to those made using the standard full protocol. These results suggest a potential enhancement of clinical practice in which efficiency and cost saving might be achieved using Abbreviated CMR for routine follow-up surveillance of TOF.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
House AV,Muthurangu V,Spanel AJ,Danford DA,Mir B,Schuster A,Hsu H,Kutty Sdoi
10.1007/s00246-018-2035-0subject
Has Abstractpub_date
2019-03-01 00:00:00pages
616-622issue
3eissn
0172-0643issn
1432-1971pii
10.1007/s00246-018-2035-0journal_volume
40pub_type
杂志文章abstract::Enlarged bronchial arteries and/or systemic-to-pulmonary collaterals have been frequently demonstrated in association with transposition of the great arteries. They are usually clinically silent, although they might be large enough to cause accelerated pulmonary vascular obstructive disease or symptomatic cardiac volu...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-007-9183-y
更新日期:2008-07-01 00:00:00
abstract::Long-term prostaglandin use is commonly associated with side effects such as cortical proliferation of the bones, hypertrophic pyloric stenosis, and soft tissue swelling of the extremities. We report a neonate with critical coarctation of the aorta, who developed second and third degree atrioventricular blocks associa...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-017-1633-6
更新日期:2017-10-01 00:00:00
abstract::Congenital heart defect (CHD) represents the most prevalent birth defect, and accounts for substantial morbidity and mortality in humans. Aggregating evidence demonstrates the genetic basis for CHD. However, CHD is a heterogeneous disease, and the genetic determinants underlying CHD in most patients remain unknown. In...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-1822-y
更新日期:2018-04-01 00:00:00
abstract::We present two term neonates in which intravenous indomethacin usage was associated with successful closure of a persistently patent arterial duct. Both children had congenital heart disease with high pulmonary blood flow following surgical placement of contralateral systemic-pulmonary artery shunts. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-004-0886-z
更新日期:2005-09-01 00:00:00
abstract::Sedation/anesthesia is critical to cardiac catheterization in the pediatric/congenital heart patient. We sought to identify current sedation/anesthesia practices, the serious adverse event rate related to airway, sedation, or anesthesia, and the rate of intra-procedural conversion from procedural sedation to the use o...
journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00246-015-1167-8
更新日期:2015-10-01 00:00:00
abstract::Anatomic evidence of intrauterine closure of ventricular septal defects (VSDs) has been reported rarely. Between 1985 and 1990, 112 autopsies were performed at the Mayo Clinic on third trimester stillborns and infants who died during the first week of life. There were 21 (19%) cases of congenital heart disease. VSD wa...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00797004
更新日期:1994-01-01 00:00:00
abstract::We report a case of isolated ventricular inversion in a 42-year-old woman. This rare congenital cardiac anomaly was corrected by an intraatrial baffle procedure. She also underwent left-sided double-chamber endocardial pacemaker implantation for postoperative tachycardia bradycardia syndrome. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0583-3
更新日期:2004-09-01 00:00:00
abstract::A newborn infant with familial Wolff-Parkinson-White (WPW) syndrome presented with a supraventricular tachycardia of 300 beats/min, refractory to digoxin and flecainide administration. Serial electropharmacologic tests were performed via the esophagus before and during oral therapy with verapamil at 40, 80, and 60 mg ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02238370
更新日期:1990-10-01 00:00:00
abstract::Persistent pulmonary hypertension of the newborn (PPHN) complicated with transposition of the great arteries (TGA) and an intact ventricular septum (IVS) often is therapy resistant and associated with an extremely poor prognosis. For this condition, opening of the ductus arteriosus (DA) by prostaglandin-E1 in conjunct...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9475-5
更新日期:2009-10-01 00:00:00
abstract::The authors hypothesized that prospective, systematic Internet searches could identify occurrences of sudden cardiac death (SCD) in athletes and would be useful for establishing a system of active surveillance. Weekly advanced Google searches of the Internet were conducted for cases of SCD in young athletes during a 1...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0717-1
更新日期:2013-01-01 00:00:00
abstract::The response to warfarin is highly variable among individuals and such variability is likely to have some genetic basis. We evaluted the effect of VKORC1 polymorphisms on warfarin response among Japanese, taking advantage of its unique population structure in which CYP2C9 *2 and *3 alleles are relatively rare. Thirty-...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-005-1150-x
更新日期:2006-11-01 00:00:00
abstract::Our purpose was to evaluate the impact of suspicion or confirmation of heart disease on the physical and psychosocial health of children. We utilized the Child Health Questionnaire (CHQ PF-50). Children ages 5 to 18 years attending a general cardiology clinic were eligible. Those with primary noncardiac diagnoses unre...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-003-0348-z
更新日期:2004-01-01 00:00:00
abstract::We present an infant with unusual anatomy and physiology of a persistent left superior vena cava (LSVC). The adverse physiologic consequences of the LSVC were corrected with percutaneous placement of vascular plugs. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9617-9
更新日期:2010-05-01 00:00:00
abstract::A surge in cortisol levels is seen after surgery with cardiopulmonary bypass (CPB). Based on evidence of attenuation of the cortisol response to repeated stress in other settings, we hypothesized that the magnitude of cortisol increase in children after a second exposure to CPB would be reduced. Serial cortisol levels...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-1959-8
更新日期:2019-01-01 00:00:00
abstract::The authors present an unusual complication of the balloon atrial septostomy procedure performed in a neonate with D-transposition of the great arteries. Cardiac tamponade developed shortly after the balloon atrial septostomy procedure and the infant was found to have a tear in the superior aspect of the left atrium, ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02076340
更新日期:1983-04-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the associations between clinical factors and cardiac function as measured by pressure-volume loops (PVLs) in a pediatric heart transplant cohort. METHODS:Patients (age < 20 years) who underwent heart transplantation presenting for a clinically indicated catheter...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-017-1758-7
更新日期:2018-02-01 00:00:00
abstract::Once a mainstay in the treatment of neonates with d-transposition of the great arteries (d-TGA), the application of balloon atrial septostomy (BAS) in the d-TGA population has become more selective. Currently, there is no clear evidence for or against a selective BAS strategy. The aims of this single-center retrospect...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02520-x
更新日期:2021-01-25 00:00:00
abstract::Fetal interventions have been performed for some congenital heart diseases. However, these procedures have not gained wide acceptance due to concerns about their efficacy and safety. The aim of this study was to report on a preliminary experience with fetal cardiac interventions in Brazil. Twenty-two cardiac intervent...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0792-3
更新日期:2014-03-01 00:00:00
abstract::The transplanted heart experiences numerous hemodynamic changes during and after cardiac transplantation. This study sought to evaluate the left ventricular myocardial mechanics in the pediatric heart transplant population using Velocity Vector Imaging (VVI). This study retrospectively evaluated 28 heart transplant re...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0205-z
更新日期:2012-06-01 00:00:00
abstract::Maximal oxygen consumption (VO2max) is the "gold standard" by which to assess functional capacity; however, it is effort dependent. VO2@RER1.0 is defined when VO2 = VCO2. Between December 22, 1997 and November 9, 2004, 305 pediatric subjects underwent cycle ergometer cardiopulmonary exercise testing, exercised to exha...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9544-9
更新日期:2010-01-01 00:00:00
abstract::We report a 6-year-old girl with superoinferior ventricles, criss-cross atrioventricular (AV) relationships with solitus atria, a D-loop, L-transposition of the great arteries, subpulmonary stenosis, but without a ventricular septal defect (VSD). The diagnosis was made by echocardiographic examination and was strength...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00795379
更新日期:1993-10-01 00:00:00
abstract::Management of warfarin in pediatric patients remains a clinical challenge. Warfarin may be administered after congenital heart surgery, and the risks of morbidity can be high. Currently, no data exist to describe the initiation of warfarin and the risk factors for morbidity in post-congenital heart surgery patients. T...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0351-3
更新日期:2012-12-01 00:00:00
abstract::During the development of so-called aneurysmal transformation of perimembranous ventricular septal defects (pmVSD), tricuspid valve (TV) morphology and function may be altered resulting in left ventricular (LV) to right atrial (RA) shunting. The feasibility and outcome of interventional closure of these pmVSD has not ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-015-1170-0
更新日期:2015-10-01 00:00:00
abstract::As a transcription factor mainly expressed in cardiovascular system, T-box 20 (TBX20) plays an important role in embryonic cardiovascular system development and adult heart function. Previous studies have identified associations of two SNPs in the T-box DNA-binding domain of TBX20 with congenital heart disease (CHD) i...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-014-1073-5
更新日期:2015-04-01 00:00:00
abstract::The outcome in a series of 23 cases of tetralogy of Fallot diagnosed prenatally was compared to published figures for this condition when (a) identified postnatally or (b) treated surgically. There was a marked difference in the survival between these groups, with the highest mortality (75%) occurring when the diagnos...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00788220
更新日期:1992-01-01 00:00:00
abstract::Magnetocardiographic mapping was performed on a 2-year-old boy who suffered from the Wolff-Parkinson-White syndrome in association with a complex congenital heart defect. The pre-excitation site was determined noninvasively from the measured cardiac magnetic fields. The location was in the same anatomic region as foun...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02310333
更新日期:1995-01-01 00:00:00
abstract::We analyzed early and late results of surgical treatment of 100 consecutive children with Down's syndrome (DS) and congenital heart defect (CHD) who were operated on between 1990 and 1997. Fifty had common atrioventricular canal (CAVC), 24 ventricular septal defect, 8 the ostium primum atrial septal defect, 8 tetralog...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900483
更新日期:1999-09-01 00:00:00
abstract::The occurrence of familial heart disease in association with tricuspid atresia is rare. The first reported instance of tricuspid atresia and Ebstein's anomaly in siblings is presented. The presence of these two distinct pathologic variants of tricuspid valve malformations in siblings suggests that these malformations ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900072
更新日期:1996-09-01 00:00:00
abstract::The effect of patent ductus arteriosus (PDA) treatment with cyclooxygenase (COX) inhibitors (indomethacin [INDO] and ibuprofen [IBU]) on regional oxygenation requires further clarification. The authors hypothesized that both INDO and IBU reduce regional tissue oxygenation in preterm neonates with PDA but that the risk...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0309-5
更新日期:2012-12-01 00:00:00
abstract::A primary rhabdomyosarcoma of the heart observed in a 3-week-old infant, provides an opportunity to review this rare clinical entity; 61 reported cases are collated. The more common sites are right ventricle, left atrium, and right atrium; the tumour may protrude into the cavity and cause obstruction. Echocardiography...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02265621
更新日期:1982-01-01 00:00:00