Abstract:
:Children with trisomy 21 have a high incidence of congenital heart disease that frequently requires surgical repair. These patients often require multiple and higher dosage sedatives during the postoperative period. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist that has sedative, analgesic, and anxiolytic properties. We report the successful use of dexmedetomidine in patients with trisomy 21 following surgical repair of congenital heart disease.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Kalyanaraman M,Costello JL,Starr JPdoi
10.1007/s00246-006-0072-6subject
Has Abstractpub_date
2007-09-01 00:00:00pages
396-9issue
5eissn
0172-0643issn
1432-1971journal_volume
28pub_type
杂志文章abstract::Five patients with ventricular inversion, corrected transposition of the great arteries, and atresia of the left-sided atrioventricular (tricuspid) valve have been observed. Three patients died in infancy, two had large interatrial communications, one with an early stage of arterial-type hypertensive pulmonary vascula...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02310996
更新日期:1986-01-01 00:00:00
abstract::Color-coded two-dimensional (2D) echocardiography confirmed the presence of severe congenital mitral regurgitation in an 8-month-old infant. Intraoperative inspection revealed an isolated perforation in the anterior leaflet. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02239570
更新日期:1990-04-01 00:00:00
abstract::A vascular approach for balloon aortic dilatation in infants is of major concern due to the high risk of femoral artery injury. To overcome this problem, a surgical right carotid artery (RCA) approach has been advocated. No reports are available on RCA after neonatal cutdown. Since 1990, RCA cutdown has been performed...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002460010202
更新日期:2001-05-01 00:00:00
abstract::Dextro-transposition of the great arteries (D-TGA) is one of the most common cyanotic heart lesions. The arterial switch operation (ASO) is the preferred surgical palliation for D-TGA. One of the primary concerns following the ASO is complications arising from the coronary artery transfer. There is a need for myocardi...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-1890-z
更新日期:2018-08-01 00:00:00
abstract::Two children with acute symptomatic pericardial effusion had unusual echocardiographic findings. In each case, the pericardial effusion was hemorrhagic. Echocardiography displayed numerous linear bands coursing across the pericardial space. Recognition of this characteristic image may predict that an acute effusion is...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00817614
更新日期:1994-03-01 00:00:00
abstract::Nesiritide is a synthetic form of B-type natriuretic peptide. It is approved for the treatment of acute exacerbations of congestive heart failure in hospitalized adult patients. It is currently under investigation for use in other settings and other patient populations. This article describes administration of nesirit...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-006-0064-6
更新日期:2007-05-01 00:00:00
abstract::The timing of pulmonary valve replacement (PVR) in asymptomatic patients with repaired tetralogy of Fallot (TOF) is typically based on cardiac magnetic resonance imaging-derived ventricular volume measurements. Current criteria do not account for sex-based differences in chamber size. The purpose of this study was to ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02181-5
更新日期:2019-10-01 00:00:00
abstract::A rare case of isolated innominate artery arising from a left persistent arterial duct with a right aortic arch is presented. Of interest in this case is the retrograde flow in the left carotid system, the history of developmental delay, and the magnetic resonance image (MRI) brain findings suggestive of asymmetric vo...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9739-0
更新日期:2010-10-01 00:00:00
abstract::We herein describe, for the first time, the fetal presentation of a case of ventricular inversion, restrictive ventricular septal defect, pulmonary stenosis, hypertensive left ventricle and double outlet right ventricle at 34 weeks of gestational age. Postnatal echocardiography confirmed the prenatal diagnosis. The pa...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-018-2048-8
更新日期:2019-01-01 00:00:00
abstract::Adult studies suggest a better functional outcome after aortic valve replacement with a pulmonary autograft compared with mechanical or homograft valves. Little is known about functional results after Ross surgery in growing children. This study reports formal exercise stress echocardiographic data from 26 pediatric R...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0218-7
更新日期:2012-06-01 00:00:00
abstract::Conotruncal heart defect is a complex form of congenital heart disease and usually has a poor prognosis. Although previous studies have identified several missense variants in GATA4 gene that may cause CTD, it remains unclear whether they are involved in CTD pathogenesis because the study population was limited. The a...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-016-1542-0
更新日期:2017-03-01 00:00:00
abstract::The objective of this study was to evaluate the incidence of pre-existing catheterization left pulmonary artery (LPA) gradients and correlation of these gradients with later LPA stenosis after successful patent ductus arteriosus (PDA) occlusion. We performed a single-center review of 130 patients with PDA closure from...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9448-8
更新日期:2009-10-01 00:00:00
abstract::Inferior sinus venosus defects (SVDs) are rare imperfections located in the inferior portion of the atrial septum, leading to an overriding inferior vena cava (IVC) and an interatrial connection. These defects have increased risk of anomalous pulmonary venous return (PAPVR) and often are confused with secundum atrial ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0449-7
更新日期:2013-02-01 00:00:00
abstract::It is documented that exercise can increase serum cardiac troponins in adults and adolescents; however, there is a lack of related studies concerning the release of cardiac troponins in children. This study investigated the influence of table tennis training on cardiac biomarkers in children. Twenty-eight male childre...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0842-x
更新日期:2014-04-01 00:00:00
abstract::The effect of patent ductus arteriosus (PDA) treatment with cyclooxygenase (COX) inhibitors (indomethacin [INDO] and ibuprofen [IBU]) on regional oxygenation requires further clarification. The authors hypothesized that both INDO and IBU reduce regional tissue oxygenation in preterm neonates with PDA but that the risk...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0309-5
更新日期:2012-12-01 00:00:00
abstract::Atrial flutter/fibrillation (AFL/AF) is a late complication in adults with repaired tetralogy of Fallot (TOF). Its effects on long-term prognosis are not fully understood. We evaluate the impact of AFL/AF in adults with repaired TOF on global mortality and unplanned hospitalizations during follow-up, and the predictor...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-019-02106-2
更新日期:2019-06-01 00:00:00
abstract::A five-day-old infant with transposition of the great arteries, ventricular septal defect, and an interrupted right aortic arch underwent successful balloon septostomy, pulmonary artery banding, and aortic arch repair. The infant also had abnormal facies with severe refractory hypocalcemia and depressed T-lymphocyte n...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02427049
更新日期:1984-07-01 00:00:00
abstract::We measured the coronary flow reserve in a 13-year-old girl with the rare anomaly of an absent left circumflex coronary artery. Although the coronary flow volume of the right coronary artery was at the same level as that of the left anterior descending coronary artery, the coronary flow reserve of the patient's right ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002460010188
更新日期:2001-03-01 00:00:00
abstract::At the University of California Davis Medical Center, a screening fetal ultrasound examination (level I or II) incorporates a comprehensive segmental evaluation of the fetal heart. This study evaluated the reliability of the fetal ultrasound exam in the detection of abnormal heart anatomy. Our retrospective study revi...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-001-0073-4
更新日期:2002-11-01 00:00:00
abstract::For adults with sickle cell disease (SCD), cardiac changes are well described and may account for up to one-fourth of disease-related mortality. Much less is known about heart disease in pediatric SCD patients. This retrospective study analyzed a contemporary cohort of children with SCD followed at a single tertiary c...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0587-y
更新日期:2013-04-01 00:00:00
abstract::Anomalous origin of left coronary artery (LCA) from the right coronary cusp with an intramural course is usually managed with unroofing of the intramural segment. Available literature demonstrates an uneventful course following surgery in most patients. Coronary stenosis following the unroofing procedure treated with ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-018-2005-6
更新日期:2019-01-01 00:00:00
abstract::The slope of the relation between the unadjusted QT interval and heart rate during the face immersion test has been reported to be useful as an index for predicting an abnormal lengthening of the QT interval for children with nonfamilial long QT syndrome. Our goals were to determine whether we can replace the slope of...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-001-0034-y
更新日期:2002-03-01 00:00:00
abstract::Acute kidney injury (AKI) is a potential complication for children with congenital heart disease (CHD) after cardiopulmonary bypass (CPB) surgery. This study was designed to investigate and compare the predictive values of urinary biomarkers for AKI after CPB surgery in infants and young children and to determine the ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0563-6
更新日期:2013-04-01 00:00:00
abstract::Horseshoe lung is a rare malformation that is often associated with lung hypoplasia and/or vascular anomalies. We describe a 10-year-old girl with horseshoe lung and unique left pulmonary vein. This is the first reported case with this vascular feature. The patient presented with signs and symptoms of severe pulmonary...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-010-9735-4
更新日期:2010-08-01 00:00:00
abstract::Exercise testing can highlight repolarisation abnormalities in adults with coronary artery disease. Late after Kawasaki disease (KD), increased QT dispersion (QTd) has been reported on resting ECG in children, but there are no reported studies of QTd during exercise. Our objective was to determine the pattern of QTd r...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0201-3
更新日期:2012-06-01 00:00:00
abstract::This report describes the use of cross-sectional imaging--echocardiography and contrast-enhanced computed tomography--to confirm the presence of a foramen-type defect of the left pericardium with herniation of the left atrial appendage. ...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02263455
更新日期:1987-01-01 00:00:00
abstract::Previous studies have evaluated left ventricular dimensions in children using two-dimensional echocardiography, but there is little information on gender differences and on the longitudinal development of the dimensions of the left ventricle. Our objective was to assess, by two-dimensional echocardiography, the normal...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02505207
更新日期:1996-05-01 00:00:00
abstract::Pediatric cardiothoracic surgery is often associated with low cardiac output in the postoperative period. This study sought to determine whether increasing heart rate via temporary atrial pacing is beneficial in augmenting cardiac output. Patients younger than 18 years who underwent cardiothoracic surgery and had no p...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-013-0687-3
更新日期:2013-10-01 00:00:00
abstract::Patients post-bidirectional Glenn (BDG) operation are at risk of left and right pulmonary artery (LPA and RPA) hypoplasia. Transthoracic echocardiograms (TTE) in active children can miss essential elements of anatomy. Procedural sedation improves image quality but increases risk of adverse events. We hypothesized that...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-020-02342-x
更新日期:2020-06-01 00:00:00
abstract::Interruption of the aortic arch and hypoplastic left heart syndrome in the same patient is exceptional. In the combined collections of the Registry of Cardiovascular Disease (St. Paul, Minnesota, U.S.A.) and the Registry of Congenital Heart Defects of the Rijksuniversiteit Gent (Gent, Belgium) three specimens were fou...
journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/BF00798068
更新日期:1995-11-01 00:00:00