Abstract：
:The aim of the study is to identify reliable quantitative fetal echocardiographic predictors for postnatal development of coarctation (CoA). In this retrospective study, we included 65 fetuses with a prenatally suspected, isolated CoA, born 2010-2018. Dimensions of the cardiac structures, aortic, and ductal arches expressed as ratios and Z-scores were analyzed in relation to outcome. Fetuses that developed CoA postnatally (34%) exhibited significantly smaller Z-scores of left cardiac structures from the mitral valve to the aortic isthmus. The most sensitive and specific predictors were a carotid-subclavian artery index (CSAI) of < 0.78 (92.3% sensitivity, 96.8% specificity) or a product of isthmus-to-duct ratio in the three-vessel trachea view (3VT) and the mitral-to-tricuspid valve ratio (I/D3VTxMV/TV) of < 0.37 (100% sensitivity, 94.6% specificity). When comparing different Z-score datasets, we observed large and highly significant differences. Postnatal CoA can be predicted with high accuracy during fetal life using CSAI or I/D3VTxMV/TV. The latter may be particularly useful if adequate sagittal aortic arch images cannot be obtained. As significant and clinically unacceptable differences in Z-scores were observed for the same measurements, this calls for a large multi-center collaboration to generate reliable fetal echocardiographic Z-scores.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Fricke K,Liuba P,Weismann CGdoi
10.1007/s00246-020-02509-6subject
Has Abstractpub_date
2020-12-23 00:00:00eissn
0172-0643issn
1432-1971pii
10.1007/s00246-020-02509-6pub_type
杂志文章abstract：:Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a heritable cardiomyopathy characterized by fibro-fatty replacement of right ventricular myocardium. Diagnostic criteria, established in 1994 and modified in 2010, are based on predominately adult manifestations of ARVC/D. The goal of this paper is ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1327-x
更新日期：2016-04-01 00:00:00
abstract：:Digoxin has been an effective treatment for fetal supraventricular tachycardia (SVT), but second-line therapy remains more controversial. Thirty-seven cases of fetal SVT were identified that received digoxin as first-line therapy. Seventeen fetuses (46%) converted to and maintained normal sinus rhythm. Flecainide was ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010279
更新日期：2001-11-01 00:00:00
abstract：:A large ductus arteriosus aneurysm can lead to potentially serious and life-threatening complications. We report a case of aneurysmal dilatation of the ductus arteriosus in a premature infant that was successfully treated with indomethacin. Thus, surgical intervention with general anesthesia could be avoided. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-1164-4
更新日期：2006-01-01 00:00:00
abstract：:Angiography remains the gold standard in the preoperative evaluation of complex pulmonary blood supply in patients with pulmonary atresia, ventricular septal defect, and major aortopulmonary collateral arteries. In neonates, balloon occlusion aortography using a Berman balloon catheter is a very effective technique. H...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0634-9
更新日期：2004-09-01 00:00:00
abstract：:Quantification of left ventricular (LV) mass by echocardiography has not been validated against the gold standard of cardiac magnetic resonance imaging (CMR) in the pediatric population. The purpose of this study was to compare LV mass by two-dimensional and conventional M-mode echocardiography versus CMR in children....
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1991-8
更新日期：2019-02-01 00:00:00
abstract：:A premature child with congenital complete heart block had an epicardial single-chamber pacemaker implanted at 2 days of age. At 21 months of age, while sitting or standing, the patient's right anterior thigh muscles contracted at her pulse rate. Surgical exploration revealed a free-floating pacemaker in her peritoneu...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900430
更新日期：1999-03-01 00:00:00
abstract：:It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00246-017-1579-8
更新日期：2017-06-01 00:00:00
abstract：:Long-term prostaglandin use is commonly associated with side effects such as cortical proliferation of the bones, hypertrophic pyloric stenosis, and soft tissue swelling of the extremities. We report a neonate with critical coarctation of the aorta, who developed second and third degree atrioventricular blocks associa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1633-6
更新日期：2017-10-01 00:00:00
abstract：:The occurrence of familial heart disease in association with tricuspid atresia is rare. The first reported instance of tricuspid atresia and Ebstein's anomaly in siblings is presented. The presence of these two distinct pathologic variants of tricuspid valve malformations in siblings suggests that these malformations ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900072
更新日期：1996-09-01 00:00:00
abstract：:Although liver fibrosis causes significant morbidity in the late postoperative period of the Fontan procedure, the diagnostic value of hyaluronic acid (HA), a serum marker of liver fibrosis, has not been established in Fontan patients. The purpose of this study was to determine whether increased serum HA concentration...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0827-9
更新日期：2014-04-01 00:00:00
abstract：:Intravascular ultrasound (IVUS) has been introduced as an accurate and minimally invasive diagnostic technique for the assessment of vascular anatomy and its abnormalities. We believe that IVUS can be used for clarifying the reasons for failure of balloon angiography in infantile coarctation of the aorta (CoA), becaus...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02503-y
更新日期：2021-01-04 00:00:00
abstract：:Magnetocardiographic mapping was performed on a 2-year-old boy who suffered from the Wolff-Parkinson-White syndrome in association with a complex congenital heart defect. The pre-excitation site was determined noninvasively from the measured cardiac magnetic fields. The location was in the same anatomic region as foun...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02310333
更新日期：1995-01-01 00:00:00
abstract：:Congenital heart defect (CHD) represents the most prevalent birth defect, and accounts for substantial morbidity and mortality in humans. Aggregating evidence demonstrates the genetic basis for CHD. However, CHD is a heterogeneous disease, and the genetic determinants underlying CHD in most patients remain unknown. In...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1822-y
更新日期：2018-04-01 00:00:00
abstract：:To reveal the association between DNMT1 polymorphisms and congenital heart disease (CHD) in child patients, a total of 224 CHD child patients as well as 199 healthy individuals were enrolled in the present study. The DNA was extracted from whole blood, and four SNPs including rs16999593, rs2228612, rs2288349 and rs104...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1093-9
更新日期：2015-06-01 00:00:00
abstract：:Recurrent congenital left atrial aneurysm presenting in a newborn as cardiac tamponade is described. Such a presentation has not been previously reported. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900269
更新日期：1998-03-01 00:00:00
abstract：:In chronic aortic insufficiency (AI), left-ventricular (LV) dysfunction must be detected early to allow timely surgery. Strain and strain rate have been used for this purpose in adults, but the value of this method in pediatric AI has not been established. Forty patients with moderate to severe AI were included in thi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0646-z
更新日期：2013-08-01 00:00:00
abstract：:Two cases of arrhythmogenic right ventricular dysplasia (ARVD) in siblings are reported. In the boy, 14 years old, the clinical history, ECG, echocardiography, and histopathological findings were consistent with ARVD. Premature ventricular contractions of left bundle branch block (LBBB) pattern were recorded but no ve...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02239576
更新日期：1990-04-01 00:00:00
abstract：:Catheter ablation in children requires placement of multiple large femoral venous sheaths and catheters. Magnetic resonance angiography (MRA) was used to evaluate the effect of indwelling lines on femoral venous blood flow. Between October 1993 and February 1994 a total of 17 patients scheduled for catheter ablation u...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900151
更新日期：1997-05-01 00:00:00
abstract：:Successful balloon valvuloplasty for critical pulmonary valve stenosis is described in an 800-g infant. A modified catheter was required to cross the valve in the smallest child known to undergo this procedure. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010288
更新日期：2001-11-01 00:00:00
abstract：:To determine the influence of heart rate (HR) on systolic time intervals (STI) in neonates, serial measurements of right ventricular (RVSTI) and left ventricular systolic time intervals (LVSTI) were made on 30 healthy term newborn infants at age 4-8 h, 24-30 h, eight days, and four weeks. STI was related to HR and age...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02336549
更新日期：1985-01-01 00:00:00
abstract：:We present a neonatal case with intractable atrial flutter that did not respond to digitalization and electrical cardioversion. Intravenous flecainide administration completely resolved the atrial flutter. Proarrhythmic effects were not induced by flecainide administration. Although the efficacy of flecainide for atri...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0226-8
更新日期：2004-03-01 00:00:00
abstract：:Acute respiratory distress syndrome (ARDS) in children after open heart surgery, although uncommon, can be a significant source of morbidity. Because high-frequency oscillatory ventilation (HFOV) had been used successfully with pediatric patients who had no congenital heart defects, this therapy was used in our unit. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0655-y
更新日期：2013-08-01 00:00:00
abstract：:Increasingly the importance of how and why we make decisions in the medical arena has been questioned. Traditionally the aeronautical and business worlds have shed a light on this complex area of human decision-making. In this review we reflect on what we already know about the complexity of decision-making in additio...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-020-02295-1
更新日期：2020-03-01 00:00:00
abstract：:Routine use of intraoperative transesophageal echocardiography (TEE) is a safe monitoring and diagnostic method during pediatric congenital cardiac surgery. However, the question of whether intraoperative TEE is accurate and cost effective for patients with tetralogy of Fallot (TOF) has not been raised. This study aim...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0423-4
更新日期：2013-02-01 00:00:00
abstract：:Paroxysmal non-reentrant supraventricular tachycardia due to double ventricular response through antegrade dual atrioventricular nodal pathways by a single atrial excitation has been reported in limited adult cases but not in pediatric patients with structurally normal hearts or with congenital heart defects. We repor...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0326-4
更新日期：2013-03-01 00:00:00
abstract：:We performed a Waterston's anastomosis on a patient with complicated tricuspid atresia when she was two months of age. At age 14 years she required left pneumonectomy for massive, idiopathic hemoptysis. Four months after the pneumonectomy we substituted a modified Fontan anastomosis for the Waterston anastomosis. Rest...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02238530
更新日期：1991-07-01 00:00:00
abstract：:We report our findings in the microscopic examination of the conduction system in four infants with glycogen storage disease, one of whom had adequate electrophysiologic studies. The electrophysiologic studies in the latter case showed P-A and A-H intervals at the lower limits of normal, but the H-V interval was just ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02265613
更新日期：1982-01-01 00:00:00
abstract：:Postoperative arrhythmia is a common complication after open heart surgery in children. JET is the most common and dangerous arrhythmia. We aimed to assess safety and efficacy of prophylactic amiodarone in preventing JET in children underwent cardiac surgery and to assess risk factors for JET among our patients. In to...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1343-5
更新日期：2016-04-01 00:00:00
abstract：:The purpose of the study was to evaluate school-age developmental and educational outcomes for children with and without a cardiac procedure in the first year of life to improve understanding of longer-term neurodevelopmental outcomes in children who have had a cardiac procedure for congenital heart disease, the most ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-2029-y
更新日期：2019-03-01 00:00:00
abstract：:Chylothorax is a well-described complication after cardiothoracic surgery in children. Medical nutritional therapy for chylothorax includes medium-chain triglyceride (MCT) formulas and reduction in enteral long-chain triglyceride intake to reduce chyle production. Human milk is usually eliminated from the diet of infa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1393-8
更新日期：2016-08-01 00:00:00
