Complete genome sequences of a novel reassortant H4N2 avian influenza virus isolated from a live poultry market in eastern China.

abstract：:Human respiratory syncytial virus (RSV) is a serious respiratory pathogen in infants and young children as well as elderly and immunocompromised populations. However, no RSV vaccines are available. We have explored the potential of virus-like particles (VLPs) as an RSV vaccine candidate. VLPs composed entirely of RSV ...

journal_title：Journal of virology

authors： McGinnes LW,Gravel KA,Finberg RW,Kurt-Jones EA,Massare MJ,Smith G,Schmidt MR,Morrison TG

更新日期：2011-01-01 00:00:00

abstract：:Venezuelan equine encephalitis virus (VEE) is an important equine and human pathogen of the Americas. In the adult mouse model, cDNA-derived, virulent V3000 inoculated subcutaneously (s.c.) causes high-titer peripheral replication followed by neuroinvasion and lethal encephalitis. A single change (G to A) at nucleotid...

journal_title：Journal of virology

authors： White LJ,Wang JG,Davis NL,Johnston RE

更新日期：2001-04-01 00:00:00

abstract：:Expression of the cellular heat shock protein 70 gene (hsp70) is transiently induced by human cytomegalovirus (HCMV) infection of permissive human diploid fibroblasts. Induction of the cellular heat shock response during critical times of infection had previously been reported to alter the growth of HCMV in vitro. Thu...

journal_title：Journal of virology

authors： Santomenna LD,Colberg-Poley AM

更新日期：1990-05-01 00:00:00

abstract：:The transcription map of the Aedes albopictus densovirus (AalDNV) brevidensovirus was identified by Northern blotting, rapid amplification of cDNA ends (RACE) analysis, and RNase protection assays. AalDNV produced mRNAs of 3,359 (NS1), 3,345 (NS2), and 1,246 (VP) nucleotides. The two overlapping P7/7.4 NS promoters em...

journal_title：Journal of virology

authors： Pham HT,Jousset FX,Perreault J,Shike H,Szelei J,Bergoin M,Tijssen P

更新日期：2013-09-01 00:00:00

abstract：:We investigated the integration sites, infectivities, and expression of Rous-associated virus-0 (Rav-0) DNAs in exogenously infected turkey and chicken cells. Restriction endonuclease analyses of the DNAs of RAV-0-infected cells indicated that unique integration sites of RAV-0 DNA were detectable in clones of RAV-0-in...

journal_title：Journal of virology

authors： Jenkins NA,Cooper GM

更新日期：1980-12-01 00:00:00

abstract：:Investigation of the human antibody response to the 1957 pandemic H2N2 influenza A virus has been largely limited to serologic studies. We generated five influenza virus hemagglutinin (HA)-reactive human monoclonal antibodies (MAbs) by hybridoma technology from the peripheral blood of healthy donors who were born betw...

journal_title：Journal of virology

authors： Krause JC,Tsibane T,Tumpey TM,Huffman CJ,Albrecht R,Blum DL,Ramos I,Fernandez-Sesma A,Edwards KM,García-Sastre A,Basler CF,Crowe JE Jr

更新日期：2012-06-01 00:00:00

abstract：:The oligosaccharide processing and secretion of hepatitis B surface antigen (HBsAg) was studied in Chinese hamster ovary cells stably transfected with the gene coding HBsAg. HBsAg was secreted from cells with a relatively long half time (ca. 5 h). This appeared to be a characteristic of HBsAg itself, since HBsAg-produ...

journal_title：Journal of virology

authors： Patzer EJ,Nakamura GR,Yaffe A

更新日期：1984-08-01 00:00:00

abstract：:Lentivectors stimulate potent immune responses to antigen transgenes and are being developed as novel genetic vaccines. To improve safety while retaining efficacy, we constructed a lentivector in which transgene expression was restricted to antigen-presenting cells using the mouse dectin-2 gene promoter. This lentivec...

journal_title：Journal of virology

authors： Lopes L,Dewannieux M,Gileadi U,Bailey R,Ikeda Y,Whittaker C,Collin MP,Cerundolo V,Tomihari M,Ariizumi K,Collins MK

更新日期：2008-01-01 00:00:00

abstract：:Simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) infections lead to rapid depletion of CD4(+) T cells from gut-associated lymphoid tissue (GALT). Although the administration of antiretroviral therapy (ART) has been shown to increase CD4(+) T-cell levels in the peripheral blood in both SIV and...

journal_title：Journal of virology

authors： George MD,Reay E,Sankaran S,Dandekar S

更新日期：2005-03-01 00:00:00

abstract：:The administration of cyclophosphamide (50 to 100 mg/kg) at 48 to 72 h before removal of murine lung or spleen mononuclear cells for culture rendered DBA/2 mice incapable of generating an effective cytotoxic T-lymphocyte response to influenza A virus-infected cells. The cytotoxic T-lymphocyte precursor frequency to in...

journal_title：Journal of virology

authors： Merluzzi VJ,Welte K,Mertelsmann RH,Souza L,Boone T,Last-Barney K

更新日期：1984-07-01 00:00:00

abstract：:Two major outer envelope glycoproteins of Epstein-Barr virus, gp350 and gp220, are known to be encoded by 3.2- and 2.5-kilobase RNAs which map to the same DNA fragment (M. Hummel, D. Thorley-Lawson, and E. Kieff, J. Virol. 49:413-417). These RNAs have the same 5' and 3' ends. The larger RNA is encoded by a 2,777-base ...

journal_title：Journal of virology

authors： Beisel C,Tanner J,Matsuo T,Thorley-Lawson D,Kezdy F,Kieff E

更新日期：1985-06-01 00:00:00

abstract：:Transfection of an Epstein-Barr virus (EBV)-encoded plasmid containing EBER caused a substantial decrease in the level of plasmid containing EBV in Akata and Mutu Burkitt's lymphoma (BL) lines, but failed to do so in other BL lines. The results suggest that EBER could replace the role of EBV, but other EBV products al...

journal_title：Journal of virology

authors： Maruo S,Nanbo A,Takada K

更新日期：2001-10-01 00:00:00

abstract：:A uniform nomenclature has been agreed upon for monoclonal antibodies directed against virus-coded proteins of simian virus 40 and polyoma virus. Blocks of numbers from PAb1 to PAb999 have been allocated to workers involved in the isolation of monoclonal antibodies of this type. The correspondence between PAb numbers ...

journal_title：Journal of virology

authors： Crawford L,Harlow E

更新日期：1982-02-01 00:00:00

abstract：:Scrapie-associated fibrils (SAFs) are abnormal filamentous structures that are uniquely associated with unconventional slow virus diseases. The antigenic relationships of SAFs from animals infected with four biologically distinct scrapie strains were investigated by using antisera raised to purified SAF proteins. Rabb...

journal_title：Journal of virology

authors： Kascsak RJ,Rubenstein R,Merz PA,Carp RI,Robakis NK,Wisniewski HM,Diringer H

更新日期：1986-09-01 00:00:00

abstract：:The interaction of simian virus 40 (SV40) T antigen (T-ag) with the viral origin has served as a model for studies of site-specific recognition of a eukaryotic replication origin and the mechanism of DNA unwinding. These studies have revealed that a motif termed the "beta-hairpin" is necessary for assembly of T-ag on ...

journal_title：Journal of virology

authors： Kumar A,Meinke G,Reese DK,Moine S,Phelan PJ,Fradet-Turcotte A,Archambault J,Bohm A,Bullock PA

更新日期：2007-05-01 00:00:00

abstract：UNLABELLED:TRIM5α proteins are a potent barrier to the cross-species transmission of retroviruses. TRIM5α proteins exhibit an ability to self-associate at many levels, ultimately leading to the formation of protein assemblies with hexagonal symmetry in vitro and cytoplasmic assemblies when expressed in cells. However, ...

journal_title：Journal of virology

authors： Sastri J,Johnsen L,Smolin N,Imam S,Mukherjee S,Lukic Z,Brandariz-Nuñez A,Robia SL,Diaz-Griffero F,Wiethoff C,Campbell EM

更新日期：2014-08-01 00:00:00

abstract：:H9N2 influenza viruses are panzootic in domestic poultry in Eurasia and since 1999 have caused transient infections in humans and pigs. To investigate the zoonotic potential of H9N2 viruses, we studied the evolution of the viruses in live-poultry markets in Hong Kong in 2003. H9N2 was the most prevalent influenza viru...

journal_title：Journal of virology

authors： Choi YK,Ozaki H,Webby RJ,Webster RG,Peiris JS,Poon L,Butt C,Leung YH,Guan Y

更新日期：2004-08-01 00:00:00

abstract：:The retrovirus restriction factor TRIM5alpha targets the viral capsid soon after entry. Here we show that the TRIM5alpha protein oligomerizes into trimers. The TRIM5alpha coiled-coil and B30.2(SPRY) domains make important contributions to the formation and/or stability of the trimers. A functionally defective TRIM5alp...

journal_title：Journal of virology

authors： Mische CC,Javanbakht H,Song B,Diaz-Griffero F,Stremlau M,Strack B,Si Z,Sodroski J

更新日期：2005-11-01 00:00:00

abstract：:Due to the limited ultrastructural information about the coronavirion, little is known about the interactions acting at the interface between nucleocapsid and viral envelope. Knowing that subtle mutations in the carboxy-terminal endodomain of the M protein are already lethal, we have now probed the equivalent domain o...

journal_title：Journal of virology

authors： Bosch BJ,de Haan CA,Rottier PJ

更新日期：2004-07-01 00:00:00

abstract：:Type C RNA viruses initially isolated from a lymphosarcoma of a gibbon ape and from a fibrosarcoma of a woolly monkey are very closely related immunologically. However, recent studies have shown that these viruses are distinguishable in a radioimmunoassay for the 12,000-molecular-weight polypeptide (p12) of the woolly...

journal_title：Journal of virology

authors： Tronick SR,Stephenson JR,Aaronson SA,Kawakami TG

更新日期：1975-01-01 00:00:00

abstract：:Crucial steps in high-risk human papillomavirus (HR-HPV)-related carcinogenesis are the integration of HR-HPV into the host genome and loss of viral episomes. The mechanisms that promote cervical neoplastic progression are, however, not clearly understood. During HR-HPV infection, the HPV E5 protein is expressed in pr...

journal_title：Journal of virology

authors： Muto V,Stellacci E,Lamberti AG,Perrotti E,Carrabba A,Matera G,Sgarbanti M,Battistini A,Liberto MC,Focà A

更新日期：2011-05-01 00:00:00

abstract：:The degree of genetic variability in the hypervariable region 1 of hepatitis C virus (HCV) was analyzed by cloning and sequencing HCV genomes obtained in paired samples of serum, liver tissue, and peripheral blood mononuclear cells (PBMC) from four chronic hepatitis C patients. Genetic variability in serum was higher ...

journal_title：Journal of virology

authors： Navas S,Martín J,Quiroga JA,Castillo I,Carreño V

更新日期：1998-02-01 00:00:00

abstract：:The membrane glycoproteins Gn and Gc of Hantaan virus (HTNV) (family Bunyaviridae) are modified by N-linked glycosylation. The glycoproteins contain six potential sites for the attachment of N-linked oligosaccharides, five sites on Gn and one on Gc. The properties of the N-linked oligosaccharide chains were analyzed b...

journal_title：Journal of virology

authors： Shi X,Elliott RM

更新日期：2004-05-01 00:00:00

abstract：:The retroviral primary transcription product is a multifunctional RNA that is utilized as pre-mRNA, mRNA, and genomic RNA. The relationship between human immunodeficiency virus type 1 (HIV-1) unspliced transcripts used as mRNA for viral protein synthesis and as virion precursor RNA (vpRNA) for encapsidation remains an...

journal_title：Journal of virology

authors： Butsch M,Boris-Lawrie K

更新日期：2000-12-01 00:00:00

abstract：:Temperature-sensitive (ts) mutants of vesicular stomatitis virus belonging to complementation groups I, II and IV inhibited the replication of wild-type vesicular stomatitis virus when mixed infections were carried out in BHK21 cells at 32, 37, and 39.5 C. The group IV mutant (ts G 41) was most effective in this regar...

journal_title：Journal of virology

authors： Youngner JS,Quagliana DO

更新日期：1976-07-01 00:00:00

abstract：:Measles virus (MeV) is an enveloped RNA virus bearing two envelope glycoproteins, the hemagglutinin (H) and fusion (F) proteins. Upon receptor binding, the H protein triggers conformational changes of the F protein, causing membrane fusion and subsequent virus entry. MeV may persist in the brain, infecting neurons and...

journal_title：Journal of virology

authors： Shirogane Y,Hashiguchi T,Yanagi Y

更新日期：2020-01-06 00:00:00

abstract：:NYVAC has been engineered as a safe, attenuated vaccinia virus (VV) vector for use in vaccination against a broad spectrum of pathogens and tumors. Due to the interest in NYVAC-based vectors as vaccines and current phase I/II clinical trials with this vector, there is a need to analyze the human host response to NYVAC...

journal_title：Journal of virology

authors： Guerra S,López-Fernández LA,Pascual-Montano A,Nájera JL,Zaballos A,Esteban M

更新日期：2006-01-01 00:00:00

abstract：:Viral interference studies have demonstrated the existence of four distinct murine leukemia virus (MuLV) receptors on NIH 3T3 mouse cells. The four viral interference groups are ecotropic MuLV; mink cell focus inducing virus (MCF); amphotropic MuLV; and 10A1, a recombinant derivative of amphotropic MuLV that uses a un...

journal_title：Journal of virology

authors： Ott D,Friedrich R,Rein A

更新日期：1990-02-01 00:00:00

abstract：:The HTLV-1 oncoprotein Tax is a potent activator of classical and alternative NF-κB pathways and is thought to promote cell proliferation and transformation via NF-κB activation. We showed recently that hyperactivation of NF-κB by Tax triggers a cellular senescence response (H. Zhi et al., PLoS Pathog. 7:e1002025, 201...

journal_title：Journal of virology

authors： Ho YK,Zhi H,DeBiaso D,Philip S,Shih HM,Giam CZ

更新日期：2012-09-01 00:00:00

abstract：:The family Geminiviridae comprises seven genera differentiated by genome organization, sequence similarity, and insect vector. Capulavirus, an eighth genus, has been proposed to accommodate two newly discovered highly divergent geminiviruses that presently have no known vector. Alfalfa leaf curl virus, identified here...

journal_title：Journal of virology

authors： Roumagnac P,Granier M,Bernardo P,Deshoux M,Ferdinand R,Galzi S,Fernandez E,Julian C,Abt I,Filloux D,Mesléard F,Varsani A,Blanc S,Martin DP,Peterschmitt M

更新日期：2015-09-01 00:00:00