Abstract:
OBJECTIVES:To develop a practical, readily applied algorithm for primary health care providers to identify, evaluate, and manage constipation in children with autism spectrum disorders (ASDs). METHODS:The Gastroenterology Committee of the Autism Speaks Autism Treatment Network (ATN), a multisite consortium of centers dedicated to improving standards of medical care for children with ASDs, guided the development of the constipation algorithm through expert opinion and literature review. The algorithm was finalized based on results of field testing by nongastrointestinal, ATN autism medical specialists at 4 ATN sites. A systematic review and grading of the literature pertaining to constipation and children with ASDs was also performed. RESULTS:Consensus among the ATN Gastroenterology Committee identified that in children with ASDs, (1) subtle or atypical symptoms might indicate the presence of constipation; (2) screening, identification, and treatment through a deliberate approach for underlying causes of constipation is appropriate; (3) diagnostic-therapeutic intervention can be provided when constipation is documented; and (4) careful follow-up after any intervention be performed to evaluate effectiveness and tolerance of the therapy. Literature review revealed limited evidence for the clinical evaluation or treatment strategies of children with ASD and constipation. CONCLUSIONS:Constipation and its underlying etiology have the potential to be effectively identified and managed using a systematic approach. Lack of evidence on this topic in the literature emphasizes the need for research.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Furuta GT,Williams K,Kooros K,Kaul A,Panzer R,Coury DL,Fuchs Gdoi
10.1542/peds.2012-0900Hsubject
Has Abstractpub_date
2012-11-01 00:00:00pages
S98-105eissn
0031-4005issn
1098-4275pii
peds.2012-0900Hjournal_volume
130 Suppl 2pub_type
杂志文章,评审相关文献
PEDIATRICS文献大全abstract:OBJECTIVES:To compare the detection of facial attributes by computer-based facial recognition software of 2-D images against standard, manual examination in fetal alcohol spectrum disorders (FASD). METHODS:Participants were gathered from the Fetal Alcohol Syndrome Epidemiology Research database. Standard frontal and o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-2028
更新日期:2017-12-01 00:00:00
abstract::Neonates born to mothers with Graves' disease are at risk for significant morbidity and mortality and need to be appropriately identified and managed. Because no consensus guidelines regarding the treatment of these newborns exist, we sought to generate a literature-based management algorithm. The suggestions include ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2015-1878
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Skin tests with soluble beta-lactams can be used to diagnose immediate and delayed hypersensitivity (HS) reactions to beta-lactam antibiotics. Very few studies have been performed with children with suspected beta-lactam allergy. In these studies, immediate HS to beta-lactams was diagnosed by skin tests in 4...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.104.4.e45
更新日期:1999-10-01 00:00:00
abstract::This study examined conceptions of illness in young adolescents. A group of 77 urban junior high school students aged 11 to 15 years were asked for their definitions of illness. Themes occurring in definitions of illness were identified and coded according to a previously developed coding scheme. Evidence in support o...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The pediatric inpatient discharge medication process is complicated, and caregivers have difficulty managing instructions. Authors of few studies evaluate systematic processes for ensuring quality in these care transitions. We aimed to improve caregiver medication management and understanding ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-2711
更新日期:2021-02-01 00:00:00
abstract::Three Laotian refugee children with chronic pulmonary complaints and findings were found to have pulmonary paragonimiasis during a one-year period in Chicago. These patients ranged from 8 to 11 years of age and the diagnosis was delayed five to six months in two children because of the unfamiliarity of American physic...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract:OBJECTIVES:Describe the cause of deaths among patients with postdiarrheal hemolytic uremic syndrome (HUS) and identify predictors of death at the time of hospital admission. METHODS:Case-control study of 17 deaths among patients with HUS identified from the Intermountain HUS Patient Registry (1970-2003) compared again...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-0785
更新日期:2006-05-01 00:00:00
abstract::The proven effectiveness of biologics and other immunomodulatory products in inflammatory rheumatic diseases has resulted in their widespread use as well as reports of potential short- and long-term complications such as infection and malignancy. These complications are especially worrisome in children who often have ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2013-0755
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Stevens-Johnson syndrome (SJS) is an uncommon, sporadic disease and outbreaks are rare. In November 2013, an outbreak of SJS was identified at Children's Hospital Colorado. METHODS:Outbreak cases were children aged 5-21 with a discharge diagnosis of SJS admitted from September 1 to November 30, 2013. Medica...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-0278
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:The impact of secondhand marijuana smoke exposure on children is unknown. New methods allow for the detection of marijuana smoke exposure in children. METHODS:We studied children who were hospitalized in Colorado and had a parent participating in a smoking cessation study; all children had urine samples rem...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2018-0820
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVES:It has been shown that maternal prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) may be a risk factor for attention-deficit/hyperactivity disorder (ADHD) in offspring. Our goal was to examine whether paternal SSRI use before conception increases the risk of ADHD in offspring. METHODS:On ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2017-1081
更新日期:2018-01-01 00:00:00
abstract::Coma, tetany, dehydration, hypotension, tachycardia, and hyperpyrexia developed in a 2 1/2-year-old girl following two hypertonic phosphate pediatric enemas. She had marked hyperphosphatemia, hypocalcemia, hypernatremia, and acidosis. Hypocalcemia due to hyperphosphatemia can explain all of these findings. Calculation...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-09-01 00:00:00
abstract:OBJECTIVES:Media Detective is a 10-lesson elementary school substance use prevention program developed on the basis of the message interpretation processing model designed to increase children's critical thinking skills about media messages and reduce intent to use tobacco and alcohol products. The purpose of this stud...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2010-0068
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Use of specific services may help to optimize health for children with autism spectrum disorder (ASD); however, little is known about their service use patterns. We aimed to (1) define service use groups and (2) determine associations of sociodemographic, developmental, behavioral, and health ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2019-1895Q
更新日期:2020-04-01 00:00:00
abstract::Anaphylaxis presents in children with rapid involvement of typically 2 or more organ systems including cutaneous, gastrointestinal, and respiratory. Caustic ingestions (CI) may also present with acute involvement of cutaneous, gastrointestinal, and respiratory systems. We present 2 cases of "missed diagnosis" that ill...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2014-2394
更新日期:2015-02-01 00:00:00
abstract::Twenty cases of gastrointestinal perforations not associated with necrotizing enterocolitis or a bowel obstruction (GPNN) were reviewed. Fifteen infants suffered perforations during cycle ventilation. Perforations were localized in the stomach, duodenum, ileum, and jejunum. To determine if the type of mechanical venti...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1985-09-01 00:00:00
abstract:OBJECTIVES:To assess the relation between exposure to maternal depression before age 5 and 5 domains of developmental vulnerability at school entry, overall, and by age at exposure. METHODS:This cohort study included all children born in Manitoba, Canada, who completed the Early Development Instrument between 2005 and...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-0794
更新日期:2020-09-01 00:00:00
abstract::The return of information from genomic sequencing in children, especially in early life, brings up complex issues around parental autonomy, the child's future autonomy, the best interest standard, and the best interests of the family. These issues are particularly important in considering the return of genomic results...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2018-1099H
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Physicians have a major influence on parental vaccine decisions. We tested a physician-targeted communication intervention designed to (1) reduce vaccine hesitancy in mothers of infants seen by trained physicians and (2) increase physician confidence in communicating about vaccines. METHODS:W...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2014-3199
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To follow up a previous retrospective analysis in which we found the use of a pacifier to be a risk factor for recurrent acute otitis media (AOM). METHOD:In the present prospective study, the occurrence of AOM and the use of a pacifier were recorded in 845 children attending day care centers during a 15-mont...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract::The Metropolitan Atlanta Developmental Disabilities Study is the first US, population-based epidemiologic study of the prevalence of mental retardation, cerebral palsy, hearing impairment, and visual impairment among school-age children. The study population consisted of children who were 10 years of age between 1985 ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::A 23-month-old girl died after 2 days' illness with rash, fever, and convulsions. Neuropathologic findings were consistent with viral hemorrhagic encephalitis in pontine tegmentum and medial thalamic areas. Human herpesvirus 6 (HHV-6) DNA was detected in pontine nuclei by in situ hybridization. In addition, polymerase...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.105.2.431
更新日期:2000-02-01 00:00:00
abstract::Complex regional pain syndrome (CRPS) type I is a painful and disabling syndrome that is accompanied by physical changes in the affected extremity. It generally occurs after trauma, manifesting as pain that is out of proportion to the inciting event. Treatment of the disorder is difficult, with many patients being ref...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-3779
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:The aim of our study was to evaluate the effect of zinc supplementation on linear growth, body composition, and growth factors in premature infants. DESIGN:Thirty-six preterm infants (gestational age: 32.0 +/- 2.1 weeks, birth weight: 1704 +/- 364 g) participated in a longitudinal double-blind, randomized cl...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.111.5.1002
更新日期:2003-05-01 00:00:00
abstract::Many physicians and parents consider immunizations routine; as a result, they fail to discuss this important aspect of health care. Parents should be educated about each vaccine and the role it plays in the well-being of their child. To ensure that parents will be able to give informed consent to have their child immu...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVE:To provide an updated birth weight-for-gestational age (BW-for-GA) reference in the United States by using the most recent, nationally representative birth data with obstetric estimates of gestational age (GA). METHODS:We abstracted 3 285 552 singleton births between 22 and 42 weeks' gestation with nonmissin...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-0076
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:Lifelong functional, adaptive, and economic outcomes of moderate to severe infantile malnutrition are not well known. We assessed social status and income at midlife in a cohort of Barbadian adults, hospitalized for protein-energy malnutrition (PEM) during the first year of life, with good nutrition and healt...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2012-0073
更新日期:2012-07-01 00:00:00
abstract::Two pediatric patients had reflex sympathetic dystrophy, which has been well described in adults but is rarely recognized in children. The syndrome consists of continuous pain, hyperesthesia, and autonomic symptoms occurring in an extremity, usually following trauma. The various types of presentation, differential dia...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-12-01 00:00:00
abstract::Congenital fibrosarcoma (CFS) is a rare fibrous tissue malignancy that usually presents in the first few years of life. It is unique among human sarcomas in that it has an excellent prognosis. We describe a temporal clustering of a number of cases of CFS and investigate the possible associated prenatal risk factors. T...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2011-1307
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:The incidence of nosocomial infections, predominantly gastrointestinal and respiratory, in children in developed countries is high, ranging from 5% to 44%. There is no effective strategy for preventing these infections. The objective of our study was to investigate the role of Lactobacillus GG (LGG) in preven...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2009-2568
更新日期:2010-05-01 00:00:00