Clinical application of interventional renal sympathetic denervation: recommendations of the Austrian Society of Hypertension 2012.

Abstract:

:Increased activity of the sympathetic nervous system plays a major role in the pathophysiology of primary arterial hypertension. Interventional renal sympathetic denervation (RSD) is a novel percutaneous treatment, decreasing sympathetic activity and consecutively blood pressure by ablating sympathetic nervous fibers located in the adventitia of the renal arteries. The procedure has been tested in several clinical trials in patients with resistant hypertension (defined as systolic office blood pressure > 160 mmHg-in diabetic patients > 150 mmHg-treated with ³ 3 antihypertensive drugs) and caused a meaningful blood pressure reduction, lasting for at least 3 years. So far, no major adverse events have been identified; however, data on the long-term consequences are lacking. The present position paper of the Austrian Society of Hypertension is aiming to assist in choosing possible indications for RSD in clinical routine, based on the available evidence in 2012.

journal_name

Wien Klin Wochenschr

authors

Weber T,Zweiker R,Watschinger B,Grüner P,Koppelstätter C,Brandt MC,Horina J,Brussee H,Hohenstein K,Lambert T,Auer J,Hoppe UC

doi

10.1007/s00508-012-0257-3

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

789-98

issue

21-22

eissn

0043-5325

issn

1613-7671

journal_volume

124

pub_type

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