The circadian rhythm of body temperature is preserved during malarial fever.

Abstract:

:Body temperature follows a circadian rhythm with a low around 6 a.m. and a peak about 12 hours later. The effect of fever on this endogenous oscillation is unknown. We obtained hourly measurements of the rectal temperature of 66 children with Plasmodium falciparum malaria. Even at febrile temperatures, the temperature followed a clear circadian rhythm. 33 patients (50%) had fever above 38 degrees C at 6 p.m. on the first day compared to only 9 (14%) at 6 a.m. the next morning. This considerable difference was also found on the second day of observation. Since in clinical practice antipyretics are often given above a certain fever threshold, the time of day should be taken into account when antipyretics are applied.

journal_name

Wien Klin Wochenschr

authors

Lell B,Brandts CH,Graninger W,Kremsner PG

subject

Has Abstract

pub_date

2000-12-07 00:00:00

pages

1014-5

issue

23

eissn

0043-5325

issn

1613-7671

journal_volume

112

pub_type

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