[Botulinum toxin type A in the treatment plan for cerebral palsy].

Abstract:

:Over the past decade a number of placebo-controlled studies have confirmed that intramuscular injections of botulinum toxin A (BTX A) has antispastic effects. Cerebral palsy is among the most frequent disorders of the growing locomotor apparatus during childhood. Weakness as well as spasticity due to lack of selective neuronal control causes functional impairment and additional mechanisms of compensation, retardation of motor development, secondary deformities of muscles and soft tissues due to a failure of muscle growth, subluxation/dislocation of joints, early osteoarthritis, and pain. Prevention of this vicious circle has to be the main goal of caring for children with spasticity. Quality of life in children with cerebral palsy can be improved by support of their daily living motor activities. Increased muscle tone can be reduced by physical exercises, by individually adapted orthoses, walkers, and wheelchairs, by manual therapy, serial casting and in certain cases by systemic drugs or by multiple-stage surgical procedures. BTX A can be used to enable these treatment possibilities or to increase their effect. In our clinical study (BTX A in 114 patients in 19952/2000) we found no major side effects. Weakness, pain or swelling occurred temporarily. Indications for the use of BTX A are pain, functional impairment, severe cosmetic problems, as well as prevention of secondary contractures, deformities, and dislocations caused by increased muscle tone. We consider the selection of patients for the use of BTX A and the development of a goal-orientated treatment plan by multidisciplinary team approach as the most important steps. Prerequisites are exact statomotoric and dynamic physical examinations, and standardised movement analysis. 3-D-gait analysis and dynamic electromyography is used in cases where functional improvement of gait is the goal of BTX A-treatment.

journal_name

Wien Klin Wochenschr

authors

Strobl W

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

30-5

eissn

0043-5325

issn

1613-7671

journal_volume

113 Suppl 4

pub_type

杂志文章,评审
  • [The influence of metabolic control on chemotactic activity in insulin-dependent diabetes mellitus (author's transl)].

    abstract::An increased incidence of infections, especially during periods of poor metabolic control is well known in patients with insulin-dependent diabetes mellitus. Therefore, we studied polymorphonuclear chemotaxis and its dependence on the degree of diabetic control in 49 patients with insulin-dependent diabetes mellitus i...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Endler AT,Zielinski C,Schernthaner G,Ludwig H

    更新日期:1978-10-27 00:00:00

  • [Lacrimal duct reconstruction in tumor surgery and following trauma].

    abstract::Traumatic injuries of the lid often affect the lower lid and the lower canaliculus. Lid destruction by tumours also frequently takes place in the medial part of the lower lid, involving the canaliculus inferior. In order to prevent chronic epiphora the lower canaliculus has to be reconstructed. The most elegant and ef...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Steinkogler FJ

    更新日期:1985-08-09 00:00:00

  • [Investigations of the effect of midodrine on carbohydrate and fat metabolism with particular reference to the diabetic metabolic state (author's transl)].

    abstract::Midodrine, which is used in the treatment of hypotensive circulatory distrubances was investigated with respect to possible effects on carbohydrate and fat metabolism in 5 healthy subjects and 7 patients with disturbed glocuse tolerance. An i.v. glucose tolerance test was carried out on both groups and was repeated a ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Brändle J,Lageder H,Irsigler K

    更新日期:1977-03-04 00:00:00

  • [The lung phospholipid content in newborn infants with idiopathic respiratory distress syndrome in relation to lung histology and survival time (author's transl)].

    abstract::In an autopsy series on 25 newborn infants who died in the perinatal period (19 with and 6 without respiratory distress syndrome [RDS]) the total phospho-lipid, lecithin, and sphingomyelin content was determined in lung homogenates as parameters of the surfactant content. Histologically, the newborn infants with RDS w...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Krepler R,Davidovits A,Eckerstorfer R,Denk H

    更新日期:1976-09-17 00:00:00

  • Thrombolytic therapy and its combination with transluminal catheter dilatation.

    abstract::The material for complete occlusion of an artery is predominantly thrombotic. The longer the occluded segment the worse are the results of PTA since the thrombotic material is not compressible. As long as this thrombotic material is not already organized, it can be lysed by thrombolytic therapy, and thus removed. Rema...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Hess H

    更新日期:1985-01-18 00:00:00

  • [Celery allergy (celery contact urticaria syndrome) and relation to allergies to other plant antigens].

    abstract::Comparative study of 13 patients (group A) with severe attacks of angio-oedema and urticaria after eating celery and 143 atopics with hypersensitivity to mugwort-pollen (group B). Due to the severity of the reactions (group A) no oral provocation tests were performed. Scratch chamber tests with raw and cooked celery (...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Kremser M,Lindemayr W

    更新日期:1983-12-09 00:00:00

  • [Correlation of skinfold thickness with bone density and estradiol, FSH and prolactin level in a sample of 231 women].

    abstract::Skin thickness was measured by means of ultrasound and correlated with the results of bone densitometry and hormonal parameters. Skin thickness and bone density were significantly correlated (p < 0.0001). These results indicated that not only bone, but also skin is a hormone-dependent organ, which responds to the meno...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Gruber D,Sator M,Frigo P,Knogler W,Huber JC

    更新日期:1995-01-01 00:00:00

  • Bordetella pertussis and Bordetella parapertussis infection in an Austrian pediatric outpatient clinic.

    abstract:OBJECTIVE:To determine the proportion of children with an acute cough and laboratory evidence of Bordetella pertussis (B. pertussis) and B. parapertussis infection. METHODS:A prospective study was done, including children aged 0 months to 16 years who attended the outpatient clinic of the Innsbruck University Hospital...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Frühwirth M,Neher C,Schmidt-Schläpfer G,Allerberger F

    更新日期:2002-06-14 00:00:00

  • [Fungal infections -- always dangerous for immunosuppressed patients (author's transl)].

    abstract::Four renal transplant recipients, treated with the immunosuppressive combination of azathioprine-prednisolone, developed organ or systemic mycoses caused by Candida albicans and, in one case, additionally by Trichophyton rubrum. Ketoconazole, a new wide-spectrum antimycotic drug, was successfully used in the treatment...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Zazgornik J,Kopsa H,Schmidt P,Marosi L,Balcke P

    更新日期:1981-07-10 00:00:00

  • [Poisoning with elementary mercury: attempted suicide by inhalation of vapors from the heated metal].

    abstract::This paper reports on a case of attempted suicide by the rare means of prolonged inhalation of fumes from heated mercury. The patient developed symptoms of acute intoxication over a period of 4 to 24 hours after the suicide attempt. This phase consisted of pulmonary, intestinal, psychopathological and neurological sig...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Fölkl H,König P

    更新日期:1983-08-26 00:00:00

  • [Ulcerative colitis in childhood and its differential diagnosis].

    abstract::Ulcerative colitis occurs before the age of 15 years in 20% and before 20 years in 40% of all patients involved. The frequency of this disease in patients at the University Children's Hospital of Munich has clearly risen over the past years. In many patients we found characteristic differences in history, clinical pic...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Harms HK,Bertele-Harms RM

    更新日期:1986-08-29 00:00:00

  • Sleep-wake cycles in preterm infants below 30 weeks of gestational age. Preliminary results of a prospective amplitude-integrated EEG study.

    abstract::In the newborn, presence of sleep-wake cycles indicates integrity and maturity of the central nervous system. By spectral EEG analysis and polygraphic recordings subtle variations of EEG background activity and behavioural patterns corresponding to early sleep-wake cycles have been found in preterm infants as young as...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Kuhle S,Klebermass K,Olischar M,Hulek M,Prusa AR,Kohlhauser C,Birnbacher R,Weninger M

    更新日期:2001-04-17 00:00:00

  • Thromboembolic complications in a patient with heparin-induced thrombocytopenia (HIT) showing cross-reactivity to a low molecular weight heparin-treatment with Org 10172 (Lomoparan).

    abstract::Heparin-induced thrombocytopenia is an immuno-mediated life-threatening side effect of heparin therapy which poses difficulties in diagnosis and major therapeutic problems. Heparin must be instantly discontinued. We describe the case of a 60-year-old male patient with type II heparin-induced thrombocytopenia, complica...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Muhm M,Claeys L,Huk I,Koppensteiner R,Kyrle PA,Minar E,Stümpflen A,Ehringer H,Polterauer P

    更新日期:1997-02-28 00:00:00

  • [Operative treatment of prostatic adenoma (author's transl)].

    abstract::The indications for operative treatment of prostatic adenomas are outlined. The three operative techniques (suprapubic adenomectomy, resection and cryosurgery) should not be considered rival procedures, but complementary methods of therapy. The postoperative mortality dropped from 5.64% in the years 1957-1967 to 1.01%...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Haschek H

    更新日期:1978-03-17 00:00:00

  • Procalcitonin in patients with acute and chronic renal insufficiency.

    abstract:BACKGROUND:Bacterial infections are associated with a high morbidity and mortality rate in patients with acute and chronic renal failure. Because C-reactive-protein (CRP) is elevated in many patients with renal failure, even in the absence of infection, procalcitonin (PCT) might be useful for the detection of systemic ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-004-0279-6

    authors: Steinbach G,Bölke E,Grünert A,Störck M,Orth K

    更新日期:2004-12-30 00:00:00

  • [Regression of florid proliferative diabetic retinopathy through achievement of normoglycaemic over five months by means of a portable insulin-dosage apparatus (author's transl)].

    abstract::A portable insulin-infusion device (Siemens-Erlangen) was used by 24-year-old juvenile onset-type diabetic woman for a period of 5 months in order to achieve normoglycaemic conditions. The patient suffered from rapidly deteriorating florid proliferative retinopathy and was practically blind. Kidney function was seriou...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Irsigler K,Kirtz H,Najemnik C,Freyler H

    更新日期:1980-04-11 00:00:00

  • [Cellular regulation of anabolism and catabolism in skeletal muscle during immobilisation, aging and critical illness].

    abstract::Skeletal muscle atrophy is associated with situations of acute and chronical illness, such as sepsis, surgery, trauma and immobility. Additionally, it is a common problem during the physiological process of aging. The myofibrillar proteins myosin and actin, which are essential for muscle contraction, are the major tar...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:10.1007/s00508-007-0817-0

    authors: Strasser EM,Wessner B,Roth E

    更新日期:2007-01-01 00:00:00

  • [Is prevention really better than healing? A discussion contribution to prevention of spinal diseases].

    abstract::Primary, secondary and tertiary prevention are usually differentiated. All preventive measures have to prevail against criteria of effectiveness and efficiency. In the case of primary prevention, the search for risk factors is particularly important. The present limits of prevention of back pain are discussed in some ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Ernst E

    更新日期:1993-01-01 00:00:00

  • [Automated exchange transfusion in premature and newborn infants with hyperbilirubinemia using a peripheral arteriovenous vascular access device].

    abstract::The technique of exchange transfusion using a plastic catheter in the umbilical vein developed by Diamond and modified by Allen was instrumental in decreasing the mortality and morbidity in newborn infants with jaundice. Allen et al. demonstrated that the development of kernicterus in infants with erythroblastosis wit...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Schober PH

    更新日期:1990-08-31 00:00:00

  • Correction to: Impaired coronary blood flow may be related to elevated homocysteine levels in patients with metabolic syndrome.

    abstract::Correction to: Wien Klin Wochenschr 2015 https://doi.org/10.1007/s00508-015-0854-z The original version of this article unfortunately contained a mistake. The first names of Dr. Ismail Dogu Kilic were interchanged. ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00508-018-1342-z

    authors: Alihanoglu YI,Yildiz BS,Özcan EE,Kilic ID,Kuru DS,Taskoylu O,Tanriverdi H,Kaftan HA,Evrengul H

    更新日期:2018-06-01 00:00:00

  • [Applications of the peroxidase-anti-peroxidase technique in dermatology (author's transl)].

    abstract::The immunohistological findings are reported in 62 cases of malignant lymphomas, pseudolymphomas and malignant histiocytic disorders of the skin. Paraffin-embedded tissue was analyzed with the Peroxidase-Antiperoxidase (PAP) Technique for the presence of intracytoplasmic immunoglobulin (IgM, IgA, IgG, Kappa, Lambda) a...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Rauch HJ,Kerl H,Kresbach H

    更新日期:1981-09-04 00:00:00

  • [Type I diabetes mellitus and pregnancy: an interdisciplinary management program].

    abstract::The obstetrical management of pregnant women with pregestational diabetes has been significantly improved throughout recent years. In the past, efforts to maintain euglycaemia during pregnancy in the presence of a labile maternal metabolism led to repeated, long-term hospitalization. In an interdisciplinary joint effo...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Feiks A,Howorka K,Nowotny C,Dadak C,Waldhäusl W

    更新日期:1987-04-03 00:00:00

  • Spinal subdural hematoma following lumbar decompressive surgery: a report of two cases.

    abstract::Spinal subdural hematoma (SSDH) following spine surgery is an extremely rare condition, with only three cases being reported in the literature. Unintended durotomy has been associated with SSDH due to alterations of pressures in the dural compartments. The objective of the present report was to report two rare cases o...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-014-0632-3

    authors: Lykissas MG,Aichmair A,Herzog RJ,Schroeder JE,Huang RC,Farmer J

    更新日期:2015-01-01 00:00:00

  • Treatment of partial thickness burns of the face with Acticoat7™ : A retrospective single center study.

    abstract:BACKGROUND:The face is affected in more than 50% of patients with extensive burn trauma. Effective treatment is of importance to avoid hypertrophic scarring, functional impairment and social stigmatization. MATERIAL AND METHODS:All patients treated with Acticoat7™ due to superficial and deep partial thickness burns of...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-020-01757-z

    authors: Nedomansky J,Oramary A,Nickl S,Fuchs G,Radtke C,Haslik W,Fochtmann-Frana A

    更新日期:2020-10-30 00:00:00

  • High-dose versus low-dose rate brachytherapy in definitive radiotherapy of cervical cancer.

    abstract:BACKGROUND:To retrospectively compare the clinical outcome in cervical cancer patients treated by external irradiation and intracavitary high-dose rate (HDR) brachytherapy with iridium 192 versus low-dose rate (LDR) brachytherapy with radium 226 or caesium 139. METHODS:450 LDR patients were treated from 1982 to 1986 a...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Kucera H,Pötter R,Knocke TH,Baldass M,Kucera E

    更新日期:2001-01-15 00:00:00

  • Specific pharmacokinetic interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum.

    abstract::The blood schizontocidal activity of lumefantrine, monodesbutyl-benflumetol (DBB) and a 999:1 combination of both compounds has been investigated in 26 fresh isolates of Plasmodium falciparum from northwestern Thailand, using the WHO standard protocol Mark II for determining the inhibition of schizont maturation. The ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-007-0861-9

    authors: Starzengruber P,Wernsdorfer G,Parizek M,Rojanawatsirivet C,Kollaritsch H,Wernsdorfer WH

    更新日期:2007-01-01 00:00:00

  • Prevalence of obesity and motor performance capabilities in Tyrolean preschool children.

    abstract:BACKGROUND:The childrens' world of movement has changed dramatically during the last decades. As a consequence motor performance decreases particularly in children affected by overweight and obesity. This study analyses the influence of the body mass index (BMI) on motor performance of pre-school children. METHODS:In ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-014-0553-1

    authors: Greier K,Riechelmann H,Burtscher M

    更新日期:2014-07-01 00:00:00

  • [Opinion of the Austrian Society of Radiology and the Austrian Society of Pneumology].

    abstract::The National Lung Screening Trial (NLST) could demonstrate, for the first time, in a prospective randomized trial, that low-dose CT screening (LD-CT) may decrease lung cancer mortality. At the moment, it is unclear how these results will be applicable to Austria. Specifically, the definition of the population at an in...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-013-0356-9

    authors: Prosch H,Studnicka M,Eisenhuber E,Olschewski H,Stiefsohn E,Hartl S,Herold C,Burghuber O,Mostbeck G,Vorstände der Österreichischen Röntgengesellschaft, Gesellschaft für Medizinische Radiologie und Nuklearmedizin und der Österreichischen

    更新日期:2013-06-01 00:00:00

  • [Occlusion of both femoral arteries in one case of ergotism (author's transl)].

    abstract::In a 29 year-old female occlusions of both femoral arteries were caused by the administration of ergotamine in the form of Cafergot-suppositories. Angiographically long smooth-walled stenoses and occlusions over a segment of approximately 5 cm length in each superficial femoral artery as well as occlusions of both tib...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Kaliman J

    更新日期:1978-03-03 00:00:00

  • Decreased cutaneous vitamin D-synthesis in heavily melanized individuals: a rare cause for pathologic fractures of the hip.

    abstract::Painful pathological fractures of the femoral neck and the subtrochanteric region of the femur are reported in two women originating from India. After exclusion of renal or intestinal causes, laboratory data on bone metabolism, scintigraphic and radiographic examinations were characteristic for the presence of seconda...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/BF03040308

    authors: Berger CE,Marteau R,Pabinger C,Kröner A,Ogris E,Engel A

    更新日期:2003-03-31 00:00:00