Abstract:
BACKGROUND AND PURPOSE:Diffusion-weighted imaging sometimes fails to detect early computed tomography (CT) ischemic lesions in acute ischemic stroke patients, which is termed reversed discrepancy (RD), but its clinical significance remains unclear. The incidence and factors associated with RD in acute ischemic stroke patients within 3 hours of onset were examined. METHODS:A total of 164 consecutive patients with acute anterior circulation ischemic stroke was enrolled. All patients underwent both magnetic resonance imaging and CT within 3 hours of onset and before treatment. Their early ischemic changes were evaluated with the Alberta Stroke Program Early CT Score. RD was defined as present when the early ischemic change detected on CT was not seen on diffusion-weighted imaging. RESULTS:RD was found in 40 patients (24%). RD group patients were older (78.7 ± 9.6 versus 74.1 ± 12.1 years; P=0.03) and had a higher admission National Institutes of Health Stroke Scale score (median, 22 versus 11; P<0.01), higher rates of atrial fibrillation (75% versus 42%; P<0.01), a higher rate of internal carotid artery/middle cerebral artery proximal occlusion (55% versus 28%; P<0.01), and lower CT-Alberta Stroke Program Early CT Score (median 5 versus 10; P<0.01) and diffusion-weighted imaging-Alberta Stroke Program Early CT Score (7 versus 9; P<0.01) than patients in the non-RD group. Multivariate logistic regression analysis demonstrated that atrial fibrillation was independently associated with the presence of RD (odds ratio, 2.47; 95% CI, 1.05-6.12). CONCLUSIONS:RD is observed in a quarter of acute ischemic stroke patients. RD should be taken into consideration, especially in patients with atrial fibrillation, to prevent underestimating the extent of ischemic lesions.
journal_name
Strokejournal_title
Strokeauthors
Kawano H,Hirano T,Nakajima M,Inatomi Y,Yonehara Tdoi
10.1161/STROKEAHA.111.000254subject
Has Abstractpub_date
2013-04-01 00:00:00pages
1056-61issue
4eissn
0039-2499issn
1524-4628pii
STROKEAHA.111.000254journal_volume
44pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Elevated leukocyte count has been associated with cardiovascular and cerebrovascular disease in several epidemiological studies. We sought to determine whether white blood cell count (WBC) is associated with carotid plaque thickness in a stroke-free, multiethnic cohort. METHODS:For this cross-se...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.32.4.842
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We studied six patients suffering from pure, unilateral brain stem infarction to explore the association of remote cerebral and cerebellar blood flow changes with damage at different sites of this region of the brain. METHODS:We used single-photon emission computed tomography and [123I]iodoamphe...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.8.1162
更新日期:1993-08-01 00:00:00
abstract::Background and Purpose- More intensive secondary prevention with newer drugs may be cost-effective in patients with coronary artery disease (CAD). Whether some subgroups of patients who had a transient ischemic attack (TIA) or ischemic stroke, but no prior CAD are at similar high risk of myocardial infarction as those...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.025831
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Limited data exist on the performance of the revised Framingham Stroke Risk Score (R-FSRS) and the R-FSRS in conjunction with nontraditional risk markers. We compared the R-FSRS, original FSRS, and the Pooled Cohort Equation for stroke prediction and assessed the improvement in discrimination by ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.018928
更新日期:2018-02-01 00:00:00
abstract::Cerebral blood flow and clinical parameters were studied in 30 stroke patients at 15th, 30th, 60th, 90th days after the cerebral insult (Xenon 133 inhalation method). The clinical improvement was not accompanied by a progressive normalization of the CBF at rest. No relationship was found between the clinical data and ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.14.1.77
更新日期:1983-01-01 00:00:00
abstract::Using a scintillation camera system, hemispheric and regional cerebral blood flow was measured repeatedly during the course after a stroke. In 20 patients who improved clinically mean hemispheric and regional flow and relative weight of rapidly perfused compartment increased, while these values decreased in 15 patient...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.7.4.399
更新日期:1976-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Improvements in cardiac surgery mortality and morbidity have focused interest on the neurological injury such as stroke and cognitive decline that may accompany an otherwise successful operation. We aimed to investigate (1) the rate of stroke, new ischemic change on MRI, and cognitive impairment ...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/STROKEAHA.107.502989
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We used Riks-Stroke, the Swedish Stroke Register, to explore how thrombolysis has been disseminated in Swedish hospitals since it was approved in 2003. METHODS:All 78 hospitals in Sweden admitting patients with acute stroke participate in Riks-Stroke. Between 2003 and 2008, 72 033 adult patients...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.109.577106
更新日期:2010-06-01 00:00:00
abstract::Many patients suffer a stroke early after a transient ischemic attack, but the reason why is often unclear. We studied 12 patients with less than 75% stenosis of the internal carotid artery and a single hemispheric transient ischemic attack lasting less than 1 hour who had a normal neurologic examination 3-13 hours la...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.1.40
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Transcranial color-coded duplex sonography (TCCS) allows bedside imaging of intracranial hemodynamics and parenchymal structures. It provides reliable information regarding midline shift (MLS) in space-occupying hemispheric stroke. We studied the value of MLS measurement to predict fatal outcome ...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.32.2.442
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Uric acid (UA) is a neuroprotective antioxidant that improves the benefits of alteplase in experimental ischemia. However, it is unknown whether endogenous UA also influences the response to thrombolysis in patients with stroke. METHODS:A total of 317 consecutive patients treated with thrombolys...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/STROKEAHA.110.596528
更新日期:2011-01-01 00:00:00
abstract::Background and Purpose- The purpose of this study was to assess recent trends in the admission and mortality rates for subarachnoid hemorrhage in Canada. Methods- This retrospective cross-sectional study was based on data retrieved from the Canadian Institute for Health Information for all patients diagnosed with suba...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.022332
更新日期:2018-11-21 00:00:00
abstract:BACKGROUND AND PURPOSE:The CHADS(2) score is used for risk stratification of ischemic stroke in patients with nonvalvular atrial fibrillation and high CHADS(2) scores are associated with increased risk of stroke. Most components of the CHADS(2) score are also risk factors for atherosclerosis. Therefore, high CHADS(2) s...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.602987
更新日期:2011-04-01 00:00:00
abstract::Exposure of Mongolian gerbils to a 100% oxygen atmosphere after 15 minutes of global brain ischemia resulted in a marked increase in the production of pentane, an in vivo product of lipid peroxidation. Much less pentane production occurred in animals subjected to global brain ischemia then exposed to an air atmosphere...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.2.426
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aimed to determine if ischemia involving Broca area predicts Broca aphasia more reliably in acute or chronic stroke. METHODS:We included consecutive right-hand-dominant patients with left hemisphere ischemic stroke (<48 hours from onset for acute stroke or >6 months after stroke for chronic s...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.570374
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Embolic complications during ultrasound examinations are a rare cause of neurological deficits. The present case documents the occurrence of embolism by a nonobstructive compression maneuver during transcranial Doppler examination, resulting in a minor stroke. CASE DESCRIPTION:A 63-year-old man ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.5.1056
更新日期:1994-05-01 00:00:00
abstract::Platelet activating factor, a potent inducer of in vivo platelet activation and thrombosis, has been shown to be excessively active in acute ischemic stroke patients. Therefore, we studied the effect of aspirin/dipyridamole therapy in inhibiting platelet activating factor-induced platelet activation in acute ischemic ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.5.609
更新日期:1989-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Autosomal dominant hypertension with brachydactyly features severe hypertension that causes stroke usually before the age of 50 years. We recently characterized the hypertension as featuring normal renin, aldosterone, and catecholamine responses and mapped the gene responsible to chromosome 12p. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.9.1749
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:An association between high lipoprotein(a) [Lp(a)] levels and positive Chlamydia pneumoniae IgG titers in coronary artery disease has been described. The possibility of predicting ischemic stroke by measurements of plasma Lp(a) and C pneumoniae antibodies was investigated. METHODS:This incident ...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.str.30.10.2013
更新日期:1999-10-01 00:00:00
abstract::In the period 1977-1982, the Danish National Patient Register recorded 1000 cases of cerebral thromboembolic attacks among women 15-44 years of age, and 971 cases among men of the same age. Cerebral infarction accounted for 70% of cases and transient ischemic attacks (TIA) for the remaining 30%. By analysing this mate...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.17.4.670
更新日期:1986-07-01 00:00:00
abstract::Cerebral autoregulation can be duplicated in vitro using the large middle cerebral arteries from a calf. The limits of autoregulation were between 50 and 150 mm Hg. Excessively high pressures may lead to the appearance of the "sausage- or bead-string" response followed by forced dilation. These results suggest the exi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.12.5.640
更新日期:1981-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To date, studies on neonatal stroke have mainly focused on cortical stroke. We have focused on perforator strokes, noncortical strokes in the arterial vascular perforator area. We sought to identify risk factors and evaluate clinical presentation and neuroimaging findings for neonatal perforator ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.001064
更新日期:2013-08-01 00:00:00
abstract::To determine the incidence of perioperative silent cerebral infarction, 97 patients who underwent carotid endarterectomy were prospectively studied with preoperative and postoperative computed tomograms. Thirty-one of 96 patients (32%) had findings of cerebral infarction on preoperative computed tomograms. Silent cere...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.3.329
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Changes in adrenoceptors in the cerebral cortex and hippocampus of Mongolian gerbils after brain ischemia were investigated. METHODS:Twenty-four hours after unilateral occlusion of the common carotid artery, alpha 1-, alpha 2-, and beta-receptors of the membrane fraction of the cerebral cortex o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.12.2333
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Screening for dysphagia is essential to the implementation of preventive therapies for patients with stroke. A systematic review was undertaken to determine the evidence-based validity of dysphagia screening items using instrumental evaluation as the reference standard. METHODS:Four databases fr...
journal_title:Stroke
pub_type: 杂志文章,meta分析,评审
doi:10.1161/STROKEAHA.111.640946
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Peri-infarct depolarizations (PIDs) that occur in ischemic boundary zones of the cerebral cortex of experimental animals have been shown to promote rather than simply to indicate the evolution of the lesion and are especially prominent in the rat. To study the influence of one factor, species, on...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.31.1.214
更新日期:2000-01-01 00:00:00
abstract::Regional cerebral ischemia was produced by common carotid artery occlusion in gerbils and by middle cerebral artery occlusion in dogs, cats, and squirrel monkeys. Anesthesia was induced with either pentobarbital or halothane and maintained for two to three hours after vessel occlusion. In acute studies, the effect of ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.6.4.405
更新日期:1975-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of the study was to determine the effects of thromboembolism and mechanical thrombectomy on the vessel wall magnetic resonance imaging (VW-MRI) appearance of the intracranial arterial wall. METHODS:This was a cross-sectional study of consecutive patients with acute intracranial arterial ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.005618
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The relationship between the pattern of alcohol intake and the risk of stroke is unclear, in particular the increased risk observed in abstainers and the possible protective effect of light to moderate drinking. For that reason, we examined in a large prospective study the role of alcohol consump...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.6.1033
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Current US guideline statements regarding primary and secondary cardiovascular risk prediction and prevention use absolute risk estimates to identify patients who are at high risk for vascular disease events and who may benefit from specific preventive interventions. These guidelines do not expli...
journal_title:Stroke
pub_type: 杂志文章,实务指引
doi:10.1161/STR.0b013e31825bcdac
更新日期:2012-07-01 00:00:00