当前位置： SCI文献检索 > PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY期刊下所有文献 > Replication of previous GWAS hits suggests the association between rs4307059 near MSNP1AS and autism in a Chinese Han population.

Replication of previous GWAS hits suggests the association between rs4307059 near MSNP1AS and autism in a Chinese Han population.

Abstract：

:Autism is a complex neurodevelopmental disorder with high heritability. Previous genome-wide association studies (GWAS) demonstrated that some single-nucleotide polymorphisms (SNPs) were significantly associated with autism, while other studies focusing on these GWAS hits showed inconsistent results. Besides, the association between these variants and autism in the Chinese Han population remains unclear. Therefore, this family-based association study was performed in 640 Chinese Han autism trios to investigate the association between autism and 7 SNPs with genome-wide significance in previous GWAS (rs4307059 near MSNP1AS, rs4141463 in MACROD2, rs2535629 in ITIH3, rs11191454 in AS3MT, rs1625579 in MIR137HG, rs11191580 in NT5C2, and rs1409313 in CUEDC2). The results showed a nominal association between the T allele of rs4307059 and autism under both additive model (T>C, Z = 2.250, P = .024) and recessive model (T>C, Z = 2.109, P = .035). The findings provided evidence that rs4307059 near MSNP1AS might be a susceptibility variant for autism in the Chinese Han population.

journal_name

Prog Neuropsychopharmacol Biol Psychiatry

journal_title

Progress in neuro-psychopharmacology & biological psychiatry

authors

Wang Z,Zhang J,Lu T,Zhang T,Jia M,Ruan Y,Zhang D,Li J,Wang L

doi

10.1016/j.pnpbp.2018.12.016

subject

Has Abstract

pub_date

2019-06-08 00:00:00

pages

194-198

eissn

0278-5846

issn

1878-4216

pii

S0278-5846(18)30752-8

journal_volume

92

pub_type

杂志文章

相关文献

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY文献大全
  • Biological markers in alcoholism.

    abstract：:The search for biological markers of a predisposition towards alcoholism is the result of data indicating that this disorder is genetically influenced. The present paper reviews some methodological considerations important for trait marker research in alcoholism. To date, the most promising results have come from stud...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0278-5846(86)90073-4

    authors： Schuckit MA

    更新日期：1986-01-01 00:00:00

  • Autoradiography reveals selective changes in serotonin binding in neocortex of patients with temporal lobe epilepsy.

    abstract：:The main goal of the present study was to evaluate binding to serotonin in the neocortex surrounding the epileptic focus of patients with mesial temporal lobe epilepsy (MTLE). Binding to 5-HT, 5-HT(1A), 5-HT(4), 5-HT(7) receptors and serotonin transporter (5-HTT) in T1-T2 gyri of 15 patients with MTLE and their correl...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2007.04.014

    authors： Rocha L,Lorigados-Pedre L,Orozco-Suárez S,Morales-Chacón L,Alonso-Vanegas M,García-Maeso I,Villeda-Hernández J,Osorio-Rico L,Estupiñán B,Quintana C

    更新日期：2007-08-15 00:00:00

  • New drug targets in the signaling pathways activated by antidepressants.

    abstract：:Studies of twins, genetic linkage and association support the existence of a genetic component to the susceptibility to depression. Biochemical parameters that change in depressive patients are also observed in their relatives. This indicates that genetic factors control these physiological changes and the susceptibil...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.pnpbp.2005.03.017

    authors： Páez-Pereda M

    更新日期：2005-07-01 00:00:00

  • The effects of serotonin modulation on medial prefrontal connectivity strength and stability: A pharmacological fMRI study with citalopram.

    abstract：BACKGROUND:Static and dynamic functional connectivity are being increasingly used to measure the effects of disease and a range of different interventions on brain networks. While preliminary evidence suggests that static connectivity can be modulated by chronic antidepressants administration in healthy individuals and...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.pnpbp.2018.01.021

    authors： Arnone D,Wise T,Walker C,Cowen PJ,Howes O,Selvaraj S

    更新日期：2018-06-08 00:00:00

  • Cholecystokinin.

    abstract：:1. CCK-peptides are distributed throughout the whole brain with the exception of the cerebellum. 2. There is strong evidence that they act as neuromodulators on the noradrenergic, opioid and mainly dopaminergic system. 3. CCK reduces food-intake. However, tolerance occurs, when chronically given. Thus, potential benef...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/0278-5846(88)90071-1

    authors： Albus M

    更新日期：1988-01-01 00:00:00

  • Characterisation of spinophilin immunoreactivity in postmortem human brain homogenates.

    abstract：:Spinophilin is a multifunctional scaffold protein that regulates the formation and function of dendritic spines and plays a role in neuronal migration. The distinct roles of spinophilin depend on its localization and the direct interaction with other proteins, which may target spinophilin to specific locations within ...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2017.09.019

    authors： Brocos-Mosquera I,Nuñez Del Moral A,Morentin B,Meana JJ,Callado LF,Erdozain AM

    更新日期：2018-02-02 00:00:00

  • The role of pro-inflammatory cytokines in neuroinflammation, neurogenesis and the neuroendocrine system in major depression.

    abstract：:Cytokines are pleiotropic molecules with important roles in inflammatory responses. Pro-inflammatory cytokines and neuroinflammation are important not only in inflammatory responses but also in neurogenesis and neuroprotection. Sustained stress and the subsequent release of pro-inflammatory cytokines lead to chronic n...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.pnpbp.2015.06.008

    authors： Kim YK,Na KS,Myint AM,Leonard BE

    更新日期：2016-01-04 00:00:00

  • Evaluating drug effects on children's cognitive functioning.

    abstract：:In our studies of drug therapy in child psychiatry disorders, we have been using a battery of tests to monitor any effects of medication on the various components of cognitive processing. Our intention was to measure skills required by the children for successful classroom performance. We have used this test battery a...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 临床试验,杂志文章

    doi：10.1016/0278-5846(84)90037-x

    authors： Ferguson HB,Simeon JG

    更新日期：1984-01-01 00:00:00

  • Sociodemographic and treatment related variables are poor predictors of haloperidol induced motor side effects.

    abstract：:Age, haloperidol plasma levels and sex are associated with haloperidol induced motor side effects according to some lines of evidence, even though some conflicting findings mandate further research. We here report that age and sex were associated with dystonia during the early phases of treatment (p = 0.0006 and p = 0...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2010.08.029

    authors： Giegling I,Drago A,Schäfer M,Möller HJ,Rujescu D,Serretti A

    更新日期：2011-01-15 00:00:00

  • Antidepressant drug action--From rapid changes on network function to network rewiring.

    abstract：:There has been significant recent progress in understanding the neurobiological mechanisms of antidepressant treatments. The delayed-onset of action of monoamine-based antidepressant drugs have been associated to their ability to slowly increase synaptic plasticity and neuronal excitability via altering neurotrophic s...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.pnpbp.2015.06.001

    authors： Rantamäki T,Yalcin I

    更新日期：2016-01-04 00:00:00

  • Methadone is substantially less effective than morphine in modifying locomotor and brain Fos responses to subsequent methadone challenge in rats.

    abstract：:Heroin addicts can benefit from methadone substitution therapy. However, little is known about the significance of pre-exposure to opioids for psychoactive effects of methadone. We modeled some behavioral and neurobiological aspects of the opioid abuse-related phenomena in Sprague-Dawley rats, using morphine (10 mg/kg...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2009.05.015

    authors： Taracha E,Chrapusta SJ,Lehner M,Skórzewska A,Płaźnik A

    更新日期：2009-08-31 00:00:00

  • Altered HDAC5 and CREB mRNA expressions in the peripheral leukocytes of major depression.

    abstract：BACKGROUND:Gene expressions of the peripheral leukocytes in depressive patients might reflect the systemic dysfunction of major depression. We determined mRNA expression levels of Histone deacetylase 5 (HDAC5) gene and cyclic AMP response element-binding protein 1 (CREB) gene in the leukocyte of depressive patients. HD...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2006.12.014

    authors： Iga J,Ueno S,Yamauchi K,Numata S,Kinouchi S,Tayoshi-Shibuya S,Song H,Ohmori T

    更新日期：2007-04-13 00:00:00

  • Understanding facial expressivity in autism spectrum disorder: An inside out review of the biological basis and clinical implications.

    abstract：:Deficits in decoding and understanding facially expressed emotions occur commonly in persons with autism spectrum disorder (ASD), which contribute to the impairment of social communication that serves as one of its core diagnostic criteria. Research suggests that abnormalities of visual scanning of the face, activatio...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.pnpbp.2018.05.009

    authors： Deutsch SI,Raffaele CT

    更新日期：2019-01-10 00:00:00

  • DRD4 gene and obsessive compulsive disorder: do symptom dimensions have specific genetic correlates?

    abstract：INTRODUCTION:The dopamine D4 receptor (DRD4) is a promising candidate gene in obsessive compulsive disorder (OCD). A 48-bp variable number of tandem repeats (VNTR) sequence in exon 3 has been studied previously, and alleles containing 2-11 repeats (2R-11R) have been identified. We investigated the association of DRD4 V...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2012.10.023

    authors： Taj M J RJ,Viswanath B,Purushottam M,Kandavel T,Janardhan Reddy YC,Jain S

    更新日期：2013-03-05 00:00:00

  • Regulation of dopamine release and metabolism in rat striatum in vivo: effects of dopamine receptor antagonists.

    abstract：:1. The acute effects of some of typical and atypical antipsychotic drugs on the dopamine release and metabolism in the dorsal striatum of freely moving rats were studied using transcerebral microdialysis technique. 2. Classical neuroleptic drugs haloperidol (0.05, 0.1 and 0.2 mg/kg), thioproperazine (0.1, 0.2 and 0.4 ...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/0278-5846(95)00267-7

    authors： Rayevsky KS,Gainetdinov RR,Grekhova TV,Sotnikova TD

    更新日期：1995-12-01 00:00:00

  • Long-term impact of chronic variable stress in adolescence versus adulthood.

    abstract：:Adolescence is a period of active development of stress regulatory neurocircuitry. As a consequence, mechanisms that control the responses to stress are not fully matured during this developmental period, which may result in vulnerability to chronic stress. We hypothesized that adolescent chronic stress would have neg...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2018.08.003

    authors： Cotella EM,Gómez AS,Lemen P,Chen C,Fernández G,Hansen C,Herman JP,Paglini MG

    更新日期：2019-01-10 00:00:00

  • Emotion regulation in mood and anxiety disorders: A meta-analysis of fMRI cognitive reappraisal studies.

    abstract：:Emotion regulation by means of cognitive reappraisal has been widely studied with functional magnetic resonance imaging (fMRI). To date, several meta-analyses of studies using cognitive reappraisal tasks in healthy volunteers have been carried out, but no meta-analyses have yet been performed on the fMRI data of clini...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.pnpbp.2017.06.001

    authors： Picó-Pérez M,Radua J,Steward T,Menchón JM,Soriano-Mas C

    更新日期：2017-10-03 00:00:00

  • Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients: a pilot double-blind randomized trial.

    abstract：:Depression is one of the most common neuropsychiatric conditions, with a lifetime prevalence approaching 17%. Although a variety of pharmaceutical agents is available for the treatment of depression, psychiatrists find that many patients cannot tolerate the side effects, do not respond adequately, or finally lose thei...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.pnpbp.2006.11.010

    authors： Akhondzadeh Basti A,Moshiri E,Noorbala AA,Jamshidi AH,Abbasi SH,Akhondzadeh S

    更新日期：2007-03-30 00:00:00

  • Dependence potential of antidepressants compared to benzodiazepines.

    abstract：:The aim of the present study was to compare the possible dependence potential of antidepressants (ADs) to benzodiazepines (BZDs). The Schedules for Clinical Assessment in Neuropsychiatry (SCAN), the Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ) and the Symptom Checklist-90 (SCL-90) were administered...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/s0278-5846(02)00209-9

    authors： van Broekhoven F,Kan CC,Zitman FG

    更新日期：2002-06-01 00:00:00

  • The compensatory antioxidant response system with a focus on neuroprogressive disorders.

    abstract：:Major antioxidant responses to increased levels of inflammatory, oxidative and nitrosative stress (ONS) are detailed. In response to increasing levels of nitric oxide, S-nitrosylation of cysteine thiol groups leads to post-transcriptional modification of many cellular proteins and thereby regulates their activity and ...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.pnpbp.2019.109708

    authors： Morris G,Puri BK,Walker AJ,Berk M,Walder K,Bortolasci CC,Marx W,Carvalho AF,Maes M

    更新日期：2019-12-20 00:00:00

  • Increasing the density of the D2L receptor and manipulating the receptor environment are required to evidence the partial agonist properties of aripiprazole.

    abstract：:The clinical efficacy of aripiprazole in the treatment of psychosis relies on a partial agonism at D2 receptors. As the expression of this receptor differs physiologically between pre- and post-synaptic sites and is affected by pathological conditions or pharmacological treatments, it appears difficult to predict the ...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2011.08.007

    authors： Koener B,Focant MC,Bosier B,Maloteaux JM,Hermans E

    更新日期：2012-01-10 00:00:00

  • Neurodevelopmental basis of bipolar disorder: a critical appraisal.

    abstract：:Neurodevelopmental factors have been implicated in the pathophysiology of mental disorders. However, the evidence regarding their role in bipolar disorder is controversial. We reviewed the pertinent literature searching for evidence regarding a neurodevelopmental origin of bipolar disorder. Findings from clinical, epi...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/j.pnpbp.2008.04.017

    authors： Sanches M,Keshavan MS,Brambilla P,Soares JC

    更新日期：2008-10-01 00:00:00

  • Effects of constant daylight exposure during early development on marmoset psychosocial behavior.

    abstract：:Due to global industrialization, the light cycle is shifting to longer daytime. Mounting evidence indicates that social developmental disorders may correlate with longer periods of daytime in childhood. However, the exact mechanisms of this link remain unclear. To examine the impact of longer day-time on psychosocial ...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2011.01.008

    authors： Senoo A,Okuya T,Sugiura Y,Mimura K,Honda Y,Tanaka I,Kodama T,Tokuno H,Yui K,Nakamura S,Usui S,Koshiba M

    更新日期：2011-08-01 00:00:00

  • Serum lipids, metabolic syndrome and lifetime suicide attempts in patients with bipolar disorder.

    abstract：OBJECTIVE:Bipolar disorder is associated with a high risk of suicide. Many clinical characteristics and, recently, biomarkers have been studied with the aim to find useful predictors of suicidality. The role of serum lipids has also been explored albeit with conflicting results; however, few studies have been focused o...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2011.12.009

    authors： D'Ambrosio V,Salvi V,Bogetto F,Maina G

    更新日期：2012-04-27 00:00:00

  • In vivo monitoring of apoptosis.

    abstract：:The biochemical and physiological processes involved in apoptosis were described from the perspective of detection by standard, clinical, noninvasive imaging modalities. The difficulties of monitoring apoptosis in vivo were discussed. Magnetic resonance imaging (MRI) approaches used to study apoptosis were surveyed. T...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章,评审

    doi：10.1016/S0278-5846(03)00026-5

    authors： Brauer M

    更新日期：2003-04-01 00:00:00

  • Age-dependent effects of esculetin on mood-related behavior and cognition from stressed mice are associated with restoring brain antioxidant status.

    abstract：:Dietary antioxidants might exert an important role in the aging process by relieving oxidative damage, a likely cause of age-associated brain dysfunctions. This study aims to investigate the influence of esculetin (6,7-dihydroxycoumarin), a naturally occurring antioxidant in the diet, on mood-related behaviors and cog...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2015.08.007

    authors： Martín-Aragón S,Villar Á,Benedí J

    更新日期：2016-02-04 00:00:00

  • Accelerated apoptosis of blood leukocytes and oxidative stress in blood of patients with major depression.

    abstract：:Acceleration of blood leukocyte apoptosis in major depression has been described. The present studies have been undertaken to estimate the level of apoptosis of blood leukocytes in patients with depression and to examine the mechanisms leading to apoptosis. Blood was taken from 29 patients with depression (age 48.2+/-...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2007.11.012

    authors： Szuster-Ciesielska A,Słotwińska M,Stachura A,Marmurowska-Michałowska H,Dubas-Slemp H,Bojarska-Junak A,Kandefer-Szerszeń M

    更新日期：2008-04-01 00:00:00

  • Adding a low dose atypical antipsychotic drug to an antidepressant induced a rapid increase of plasma brain-derived neurotrophic factor levels in patients with treatment-resistant depression.

    abstract：:Only two-thirds of depressive patients respond to antidepressant treatment. Recently, addition of an atypical antipsychotic drug to ongoing treatment with an antidepressant has been considered effective and well-tolerated. In the present study, we examined the effects of various atypical antipsychotic drugs as adjuvan...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2009.12.003

    authors： Yoshimura R,Ikenouchi-Sugita A,Hori H,Umene-Nakano W,Katsuki A,Hayashi K,Ueda N,Nakamura J

    更新日期：2010-03-17 00:00:00

  • Comparisons of methamphetamine psychotic and schizophrenic symptoms: a differential item functioning analysis.

    abstract：:The concept of negative symptoms in methamphetamine (MA) psychosis (e.g., poverty of speech, flatten affect, and loss of drive) is still uncertain. This study aimed to use differential item functioning (DIF) statistical techniques to differentiate the severity of psychotic symptoms between MA psychotic and schizophren...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2011.01.014

    authors： Srisurapanont M,Arunpongpaisal S,Wada K,Marsden J,Ali R,Kongsakon R

    更新日期：2011-06-01 00:00:00

  • Interactions between mecamylamine and alcohol in Long-Evans rats: flash-evoked potentials, body temperature, behavior, and blood alcohol concentration.

    abstract：:Mecamylamine, a noncompetitive antagonist of nicotinic acetylcholine receptors, has many potential clinical applications, including treating alcohol dependency. However, little is known about the combined effects of mecamylamine and alcohol on visual system electrophysiology. We examined the separate and combined effe...

    journal_title：Progress in neuro-psychopharmacology & biological psychiatry

    pub_type： 杂志文章

    doi：10.1016/j.pnpbp.2012.11.016

    authors： Hetzler BE,Bauer AM

    更新日期：2013-06-03 00:00:00