On the threshold - evaluation of variability in effects of acupuncture in a gender perspective.

Abstract:

: Variable results of pain alleviation in response to acupuncture have been reported, complicating its interpretation. Sources of variability are probably multi-factorial, including the contribution of gender related effects. Gender related variation in perceived pain has been discussed frequently, but documented effects of acupuncture referring to gender are sparse. Furthermore, factors such as operationalisation of the outcome variable and the statistical method for evaluation could also be sources of variability. When pain is regarded as subjective, the produced data should be treated as ordinal. The rank-based method by Svensson, taking the non-metric qualities of the ordinal data into account as well as the variability at the group and the individual level, is therefore an alternative. The present commentary aims to (1) evaluate changes in electrical sensory thresholds and electrical pain thresholds after low frequency electro-acupuncture separately in healthy women and men; (2) introduce and exemplify the method by Svensson in a user-friendly approach. To analyze the systematic patterns of change in thresholds, indicating evidence of treatment on a group level, the relative position (RP) and relative concentration (RC), were measured. The variation related to the individual, the relative rank variation (RV) was also measured. The results were divergent between women (n = 23) and men (n = 22), i.e. unchanged sensory threshold after acupuncture at the group level in women while changed in men. The assessed pain threshold after acupuncture on the other hand was changed towards higher levels in women and unchanged in men. The individual variation was apparent in both women and men but larger in women. For statistical analysis of the variability for both group and individual related effects, the rank-based method by Svensson could be used. The present study indicates that evaluation of sensory and pain threshold response should be analysed separately in women and men.

journal_name

Chin Med

journal_title

Chinese medicine

authors

Lund I,Lundeberg T

doi

10.1186/1749-8546-5-32

subject

Has Abstract

pub_date

2010-09-04 00:00:00

pages

32

issn

1749-8546

pii

1749-8546-5-32

journal_volume

5

pub_type

社论
  • Identifying roles of "Jun-Chen-Zuo-Shi" component herbs of QiShenYiQi formula in treating acute myocardial ischemia by network pharmacology.

    abstract:BACKGROUND:The role of "Jun-Chen-Zuo-Shi" (also known as "sovereign-minister-assistant-courier") component herbs of Chinese medicine is not fully understood. This study aims to test the "Jun-Chen-Zuo-Shi" rule with the QiShenYiQi formula (QSYQ) on treating acute myocardial ischemia (AMI) by a network pharmacology appro...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-9-24

    authors: Wu L,Wang Y,Li Z,Zhang B,Cheng Y,Fan X

    更新日期:2014-09-16 00:00:00

  • Indication of nerve growth factor binding components from herbal extracts by HerboChip: a platform for drug screening on a chip.

    abstract:BACKGROUND:HerboChip is an array of different fractions deriving from herbal extracts. This study aimed to identify effective components from Chinese medicine (CM) that interact with nerve growth factor (NGF) as a target using HerboChip. METHODS:Fifty types of CM that are traditionally used as remedies for emotion imb...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-016-0107-8

    authors: Lee PS,Zhang LM,Yan AL,Lam KY,Dong TT,Lin H,Chan GK,Tsim KW

    更新日期:2016-07-23 00:00:00

  • Micronized sacchachitin promotes satellite cell proliferation through TAK1-JNK-AP-1 signaling pathway predominantly by TLR2 activation.

    abstract:BACKGROUND:Ganoderma sp., such as Ganoderma tsugae (GT), play an important role in traditional Chinese medicine. Ganoderma sp. contains several constituents, including Sacacchin, which has recently drawn attention because it can not only enhance the repair of muscle damage but also strengthen the muscle enforcement. Al...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-020-00381-3

    authors: Wu MH,Lin CY,Hou CY,Sheu MT,Chang H

    更新日期:2020-09-22 00:00:00

  • Metabonomic analysis of water extracts from Chinese and American ginsengs by 1H nuclear magnetic resonance: identification of chemical profile for quality control.

    abstract:UNLABELLED: BACKGROUND:With the gaining popularity of commercially prepared decoctions of herbal medicines on the market, an objective and efficient way to reveal the authenticity of such products is urgently needed. Previous attempts to use chromatographic or spectroscopic methods to identify ginseng samples made use...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-7-25

    authors: Chan PH,Zheng KY,Tsim KW,Lam H

    更新日期:2012-11-12 00:00:00

  • Antimicrobial and antioxidant activities of Cortex Magnoliae Officinalis and some other medicinal plants commonly used in South-East Asia.

    abstract:BACKGROUND:Eight medicinal plants were tested for their antimicrobial and antioxidant activities. Different extraction methods were also tested for their effects on the bioactivities of the medicinal plants. METHODS:Eight plants, namely Herba Polygonis Hydropiperis (Laliaocao), Folium Murraya Koenigii (Jialiye), Rhizo...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-3-15

    authors: Chan LW,Cheah EL,Saw CL,Weng W,Heng PW

    更新日期:2008-11-28 00:00:00

  • Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen).

    abstract:BACKGROUND:Radix Wikstroemiae is a common Chinese herbal medicine. The ethyl acetate fraction of the ethanolic extract of W. indica possesses potent in vitro antiviral activity against respiratory syncytial virus (RSV). This study aims to identify the antiviral components of the active fraction. METHODS:The active fra...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-5-23

    authors: Huang W,Zhang X,Wang Y,Ye W,Ooi VE,Chung HY,Li Y

    更新日期:2010-06-21 00:00:00

  • The drug likeness analysis of anti-inflammatory clerodane diterpenoids.

    abstract::Inflammation is an active defense response of the body against external stimuli. Long term low-grade inflammation has been considered as a deteriorated factor for aging, cancer, neurodegeneration and metabolic disorders. The clinically used glucocorticoids and non-steroidal anti-inflammatory drugs are not suitable for...

    journal_title:Chinese medicine

    pub_type: 杂志文章,评审

    doi:10.1186/s13020-020-00407-w

    authors: Feng Z,Cao J,Zhang Q,Lin L

    更新日期:2020-12-09 00:00:00

  • Aikeqing decreases viral loads in SHIV89.6-infected Chinese rhesus macaques.

    abstract:BACKGROUND:Aikeqing (AKQ) has been shown in clinical studies to improve quality of life of HIV/AIDS patients, but anti-HIV activity has not been determined. The SHIV-infected macaque is an important animal model for testing antiviral drugs. This study aimed to determine the anti-HIV activity of AKQ in chronically SHIV8...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-016-0105-x

    authors: Zhang GH,Han JB,Zhu L,Luo RH,Zhang XH,Chen X,Hu YJ,Fu LC,Zheng YT

    更新日期:2016-07-01 00:00:00

  • Inquiry diagnosis of coronary heart disease in Chinese medicine based on symptom-syndrome interactions.

    abstract:BACKGROUND:There is a long history of coronary heart disease (CHD) diagnosis and treatment in Chinese medicine (CM), but a formalized description of CM knowledge is still unavailable. This study aims to analyze a set of CM clinical data, which is important and urgent. METHODS:Relative associated density (RAD) was used...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-7-9

    authors: Li GZ,Sun S,You M,Wang YL,Liu GP

    更新日期:2012-04-05 00:00:00

  • Further validation of the Health Scale of Traditional Chinese Medicine (HSTCM).

    abstract:BACKGROUND:Few health measurement scales are based on Chinese medicine theory. The Health Scale of Traditional Chinese Medicine (HSTCM) was developed to fill this gap. The aim of this study is to validate the HSTCM. METHODS:A convenience sample of 630 participants was recruited in 11 settings. All participants were as...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-4-8

    authors: Wu D,Lai S,Zhou L,Guo X,Liang W,Wen Z,Ou A,Zhang G,Chen K

    更新日期:2009-04-30 00:00:00

  • A network pharmacology-based strategy deciphers the underlying molecular mechanisms of Qixuehe Capsule in the treatment of menstrual disorders.

    abstract:BACKGROUND:QiXueHe Capsule (QXHC) is a Chinese patent drug that is extensively used for the treatment of menstrual disorders. However, its underlying pharmacological mechanisms have not been fully elucidated. METHODS:A list of QXHC putative targets were predicted using MetaDrug. An interaction network using links betw...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-017-0145-x

    authors: Zhang Y,Mao X,Su J,Geng Y,Guo R,Tang S,Li J,Xiao X,Xu H,Yang H

    更新日期:2017-08-21 00:00:00

  • The development of an herbal material quality control strategy considering the effects of manufacturing processes.

    abstract:Background:Quality by design (QbD) is an advanced drug quality control concept that has been gradually implemented in the optimization of manufacturing processes of Chinese medicines. However, the variation of Chinese medicinal material quality has rarely been considered in published works. Because manufacturing proces...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-019-0262-9

    authors: Pan J,He S,Zheng J,Shao J,Li N,Gong Y,Gong X

    更新日期:2019-09-24 00:00:00

  • Integrated chemometric fingerprints of antioxidant activities and HPLC-DAD-CL for assessing the quality of the processed roots of Polygonum multiflorum Thunb. (Heshouwu).

    abstract:BACKGROUND:The processed roots of Polygonum multiflorum Thunb. (Heshouwu; processed HSW) are commonly used in anti-aging medicine. Few reports have combined chemical profiles with bioactivity to evaluate the quality of the processed HSW. This study aims to integrate chemometric fingerprints of antioxidant activities an...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-016-0087-8

    authors: Chen HF,Chen YH,Liu CH,Wang L,Chen X,Yu BY,Qi J

    更新日期:2016-04-12 00:00:00

  • Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models.

    abstract:BACKGROUND:KHU14, an ethanolic extract of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) was tested for its anti-inflammatory effects. METHODS:Three out of 20 herbs were found to have anti-inflammatory effects. The formulation of these herbs, i.e. KHU1...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-3-10

    authors: Kim KS,Rhee HI,Park EK,Jung K,Jeon HJ,Kim JH,Yoo H,Han CK,Cho YB,Ryu CJ,Yang HI,Yoo MC

    更新日期:2008-09-02 00:00:00

  • Phellinus linteus polysaccharide extracts increase the mitochondrial membrane potential and cause apoptotic death of THP-1 monocytes.

    abstract:BACKGROUND:The differentiation resp. death of human monocytic THP-1 cells induced by polysaccharide extracts of the medicinal mushrooms Phellinus linteus, Agaricus bisporus and Agaricus brasiliensis have been studied. This study aims to identify leads for the causal effects of these mushroom components on cell differen...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-8-25

    authors: van Griensven LJ,Verhoeven HA

    更新日期:2013-12-18 00:00:00

  • Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits.

    abstract:Background:Chronic alcohol consumption disrupts psychomotor and cognitive functions, most of which are subserved by the dysfunction of hippocampus. Dysregulated excitatory glutamatergic transmission is implicated in repeated alcohol induced psychomotor and cognitive impairment. Ginsenoside Rg1, one of the main active i...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-020-00325-x

    authors: Huang L,Peng Z,Lu C,Chen Y,Lv JW,Qin M,Liao DF,Liu XM,Shi Z

    更新日期:2020-05-07 00:00:00

  • Myofascial trigger points: spontaneous electrical activity and its consequences for pain induction and propagation.

    abstract:: Active myofascial trigger points are one of the major peripheral pain generators for regional and generalized musculoskeletal pain conditions. Myofascial trigger points are also the targets for acupuncture and/or dry needling therapies. Recent evidence in the understanding of the pathophysiology of myofascial trigger...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-6-13

    authors: Ge HY,Fernández-de-Las-Peñas C,Yue SW

    更新日期:2011-03-25 00:00:00

  • A network pharmacology-based study on the anti-hepatoma effect of Radix Salviae Miltiorrhizae.

    abstract:Background:Radix Salviae Miltiorrhizae (RSM), a well-known traditional Chinese medicine, has been shown to inhibit tumorigenesis in various human cancers. However, the anticancer effects of RSM on human hepatocellular carcinoma (HCC) and the underlying mechanisms of action remain to be fully elucidated. Methods:In thi...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-019-0249-6

    authors: Luo Y,Feng Y,Song L,He GQ,Li S,Bai SS,Huang YJ,Li SY,Almutairi MM,Shi HL,Wang Q,Hong M

    更新日期:2019-08-06 00:00:00

  • A concise classification of bencao (materia medica).

    abstract::Books that record the sources and applications of medicinal materials are commonly known as bencao (materia medica) in China. Bencao (materia medica) literature review is the very first step in the standard authentication procedure of Chinese medicinals. As an important part of China's cultural heritage, these various...

    journal_title:Chinese medicine

    pub_type: 杂志文章,评审

    doi:10.1186/s13020-018-0176-y

    authors: Zhao Z,Guo P,Brand E

    更新日期:2018-04-10 00:00:00

  • Effects of chrysin (5,7-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension in rats.

    abstract:BACKGROUND:Chrysin (5,7-dihydroxyflavone) inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation and arterial intima hyperplasia. This study aims to investigate the effects of chrysin on rat pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension (PH). METHODS:Sprague...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-015-0032-2

    authors: Li XW,Wang XM,Li S,Yang JR

    更新日期:2015-02-18 00:00:00

  • Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B.

    abstract:BACKGROUND:Radix Salvia miltiorrhiza (Danshen) has been used as a principal herb in treating cardiovascular diseases in Chinese medicine. Salvianolic acid B (SA-B), a water-soluble active component of Danshen, was found to have anti-myocardial ischemia (anti-MI) effect. This study aims to investigate mechanisms of SA-B...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-7-6

    authors: Lu Y,Zheng Y,Liu X,Liang X,Ngai S,Li T,Zhang W

    更新日期:2012-03-13 00:00:00

  • Scope of claim coverage in patents of fufang Chinese herbal drugs: Substitution of ingredients.

    abstract:: Herbal ingredients in a Chinese fufang prescription are often replaced by one or several other herbal combinations. As there have been very few Chinese herbal patent infringement cases, it is still unclear how the Doctrine of Equivalents should be applied to determine the scope of 'equivalents' in Chinese fufang pres...

    journal_title:Chinese medicine

    pub_type: 社论

    doi:10.1186/1749-8546-6-30

    authors: Wang X,Tian J,Chan AW

    更新日期:2011-08-19 00:00:00

  • Polyglycolic acid sutures embedded in abdominal acupoints for treatment of simple obesity in adults: a randomized control trial.

    abstract:Background:Acupoint catgut embedding therapy characterized by acupoint, needle and catgut are superior to traditional acupuncture, due to exerting more comprehensive therapeutic efficacy. However, it is still deficient in clinical evidence for polyglycolic acid sutures, a novel biodegradable material instead of catgut,...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-019-0258-5

    authors: Chen LS,Li YY,Chen H,Liu BW,Wang DW,Zhao YH

    更新日期:2019-09-18 00:00:00

  • Application of delayed luminescence measurements for the identification of herbal materials: a step toward rapid quality control.

    abstract:Background:Herbal materials are widely used as medicinal products, dietary supplements, food, and spices. With increased consumption, the safety, quality, and efficacy of herbal materials are becoming more relevant. The authenticity of herbal materials plays an important role in herbal quality control, and there is an ...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-019-0269-2

    authors: Sun M,Wang S,Jing Y,Li L,He M,Jia Y,van Wijk E,Wang Y,Wang Z,Wang M

    更新日期:2019-10-28 00:00:00

  • Traditional Chinese medicine Biqi capsule compared with leflunomide in combination with methotrexate in patients with rheumatoid arthritis: a randomized controlled trial.

    abstract:Background:Biqi capsule is a traditional Chinese medicine widely used as a complementary and alternative treatment for rheumatoid arthritis (RA). The objective is to understand the efficacy, safety and mechanism of Biqi combined with methotrexate (MTX) in RA. Methods:We present a randomized, controlled pilot trial on ...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-020-00319-9

    authors: Wang Z,Wu J,Li D,Tang X,Zhao Y,Cai X,Chen X,Chen X,Huang Q,Huang R

    更新日期:2020-04-23 00:00:00

  • Prescription profile of Chinese herbal products containing coumestrol, genestein, and/or daidzein among female users: an analysis of national health insurance data in Taiwan between 1997 and 2007.

    abstract:UNLABELLED: BACKGROUND:Some Chinese herbs contain several kinds of phytoestrogens, and these herbs are commonly prescribed in Taiwan. Phytoestrogens may influence the effects of estrogen in females, although their activities are weak. This study aims to identify the risk and analyze the prescription profile of commonl...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-7-22

    authors: Wu CT,Tzeng JN,Lai JN,Tsan SH,Wang JD

    更新日期:2012-10-16 00:00:00

  • Efficacy of acupuncture in the prevention and treatment of chemotherapy-induced nausea and vomiting in patients with advanced cancer: a multi-center, single-blind, randomized, sham-controlled clinical research.

    abstract:Background:Chemotherapy-induced nausea and vomiting (CINV) is a common and distressing side effect. We conducted this clinical trial to compare the effectiveness of true acupuncture vs. sham acupuncture in controlling chemotherapy-induced nausea and vomiting (CINV) among patients with advanced cancer. Methods:A total ...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-020-00333-x

    authors: Li QW,Yu MW,Wang XM,Yang GW,Wang H,Zhang CX,Xue N,Xu WR,Zhang Y,Cheng PY,Yang L,Fu Q,Yang Z

    更新日期:2020-06-03 00:00:00

  • Qing-dai powder promotes recovery of colitis by inhibiting inflammatory responses of colonic macrophages in dextran sulfate sodium-treated mice.

    abstract:BACKGROUND:Qing-dai powder (QDP), comprising Indigo naturalis (Qing-dai) and dried alum (Ku-fan), was used in Chinese medicine to treat the conditions associated with mucosal hemorrhage, such as ulcerative colitis (UC). This study aims to investigate the effects and potential mechanism of QDP on dextran sulfate sodium ...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-015-0061-x

    authors: Xiao HT,Peng J,Hu DD,Lin CY,Du B,Tsang SW,Lin ZS,Zhang XJ,Lueng FP,Han QB,Bian ZX

    更新日期:2015-10-13 00:00:00

  • Metabolic profiling reveals therapeutic effects of Herba Cistanches in an animal model of hydrocortisone-induced 'kidney-deficiency syndrome'.

    abstract:BACKGROUND:Herba Cistanches (Roucongrong) is effective in treating Shenxu Zheng ('kidney-deficiency syndrome'). However, the mechanisms and systemic metabolic responses to the herbal intervention are unclear. METHODS:Using GC-MS-based metabolic profiling, we investigated the metabolic responses to Herba Cistanches int...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/1749-8546-3-3

    authors: Qiu Y,Chen M,Su M,Xie G,Li X,Zhou M,Zhao A,Jiang J,Jia W

    更新日期:2008-03-10 00:00:00

  • Selection and validation of reference genes for normalization of quantitative real-time reverse transcription PCR analysis in Poria cocos (Schw.) Wolf (Fuling).

    abstract:BACKGROUND:Quantitative real-time reverse transcription PCR (qRT-PCR) requires a stable internal control to avoid misinterpretation of data or errors for gene expression normalization. However, there are still no validated reference genes for stable internal control in Poria cocos (Schw.) Wolf (Fuling). This study aims...

    journal_title:Chinese medicine

    pub_type: 杂志文章

    doi:10.1186/s13020-016-0079-8

    authors: Zhang X,Xu ZC,Xu J,Ji AJ,Luo HM,Song JY,Sun C,Hu YL,Chen SL

    更新日期:2016-03-02 00:00:00