Indication of nerve growth factor binding components from herbal extracts by HerboChip: a platform for drug screening on a chip.

abstract：BACKGROUND:Ganoderma sp., such as Ganoderma tsugae (GT), play an important role in traditional Chinese medicine. Ganoderma sp. contains several constituents, including Sacacchin, which has recently drawn attention because it can not only enhance the repair of muscle damage but also strengthen the muscle enforcement. Al...

journal_title：Chinese medicine

authors： Wu MH,Lin CY,Hou CY,Sheu MT,Chang H

更新日期：2020-09-22 00:00:00

abstract：Background:Herbal materials are widely used as medicinal products, dietary supplements, food, and spices. With increased consumption, the safety, quality, and efficacy of herbal materials are becoming more relevant. The authenticity of herbal materials plays an important role in herbal quality control, and there is an ...

journal_title：Chinese medicine

authors： Sun M,Wang S,Jing Y,Li L,He M,Jia Y,van Wijk E,Wang Y,Wang Z,Wang M

更新日期：2019-10-28 00:00:00

abstract：:Differential proteomics, which has been widely used in studying of traditional Chinese medicines (TCMs) during the past 10 years, is a powerful tool to visualize differentially expressed proteins and analyzes their functions. In this paper, the applications of differential proteomics in exploring the action mechanisms...

journal_title：Chinese medicine

authors： Yang YY,Yang FQ,Gao JL

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:QiXueHe Capsule (QXHC) is a Chinese patent drug that is extensively used for the treatment of menstrual disorders. However, its underlying pharmacological mechanisms have not been fully elucidated. METHODS:A list of QXHC putative targets were predicted using MetaDrug. An interaction network using links betw...

journal_title：Chinese medicine

authors： Zhang Y,Mao X,Su J,Geng Y,Guo R,Tang S,Li J,Xiao X,Xu H,Yang H

更新日期：2017-08-21 00:00:00

abstract：BACKGROUND:The role of "Jun-Chen-Zuo-Shi" (also known as "sovereign-minister-assistant-courier") component herbs of Chinese medicine is not fully understood. This study aims to test the "Jun-Chen-Zuo-Shi" rule with the QiShenYiQi formula (QSYQ) on treating acute myocardial ischemia (AMI) by a network pharmacology appro...

journal_title：Chinese medicine

authors： Wu L,Wang Y,Li Z,Zhang B,Cheng Y,Fan X

更新日期：2014-09-16 00:00:00

abstract：Background:Biqi capsule is a traditional Chinese medicine widely used as a complementary and alternative treatment for rheumatoid arthritis (RA). The objective is to understand the efficacy, safety and mechanism of Biqi combined with methotrexate (MTX) in RA. Methods:We present a randomized, controlled pilot trial on ...

journal_title：Chinese medicine

authors： Wang Z,Wu J,Li D,Tang X,Zhao Y,Cai X,Chen X,Chen X,Huang Q,Huang R

更新日期：2020-04-23 00:00:00

abstract：: One of the biggest obstacles to progress in modern pharmaceutical research is the difficulty of integrating all available research findings into effective therapies for humans. Studies of traditionally used pharmacologically active plants and other substances in traditional medicines may be valuable sources of previo...

journal_title：Chinese medicine

authors： Samwald M,Dumontier M,Zhao J,Luciano JS,Marshall MS,Cheung K

更新日期：2010-12-17 00:00:00

abstract：: Variable results of pain alleviation in response to acupuncture have been reported, complicating its interpretation. Sources of variability are probably multi-factorial, including the contribution of gender related effects. Gender related variation in perceived pain has been discussed frequently, but documented effec...

journal_title：Chinese medicine

authors： Lund I,Lundeberg T

更新日期：2010-09-04 00:00:00

abstract：BACKGROUND:KHU14, an ethanolic extract of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) was tested for its anti-inflammatory effects. METHODS:Three out of 20 herbs were found to have anti-inflammatory effects. The formulation of these herbs, i.e. KHU1...

journal_title：Chinese medicine

authors： Kim KS,Rhee HI,Park EK,Jung K,Jeon HJ,Kim JH,Yoo H,Han CK,Cho YB,Ryu CJ,Yang HI,Yoo MC

更新日期：2008-09-02 00:00:00

abstract：Background:Radix Salviae Miltiorrhizae (RSM), a well-known traditional Chinese medicine, has been shown to inhibit tumorigenesis in various human cancers. However, the anticancer effects of RSM on human hepatocellular carcinoma (HCC) and the underlying mechanisms of action remain to be fully elucidated. Methods:In thi...

journal_title：Chinese medicine

authors： Luo Y,Feng Y,Song L,He GQ,Li S,Bai SS,Huang YJ,Li SY,Almutairi MM,Shi HL,Wang Q,Hong M

更新日期：2019-08-06 00:00:00

abstract：:Books that record the sources and applications of medicinal materials are commonly known as bencao (materia medica) in China. Bencao (materia medica) literature review is the very first step in the standard authentication procedure of Chinese medicinals. As an important part of China's cultural heritage, these various...

journal_title：Chinese medicine

authors： Zhao Z,Guo P,Brand E

更新日期：2018-04-10 00:00:00

abstract：Background:Quality by design (QbD) is an advanced drug quality control concept that has been gradually implemented in the optimization of manufacturing processes of Chinese medicines. However, the variation of Chinese medicinal material quality has rarely been considered in published works. Because manufacturing proces...

journal_title：Chinese medicine

authors： Pan J,He S,Zheng J,Shao J,Li N,Gong Y,Gong X

更新日期：2019-09-24 00:00:00

abstract：BACKGROUND:Arctium lappa (Niubang), a Chinese herbal medicine, is used to treat tissue inflammation. This study investigates the effects of arctigenin (AC), isolated from A. lappa, on anti-CD3/CD28 Ab-stimulated cell proliferation and cytokine gene expression in primary human T lymphocytes. METHODS:Cell proliferation ...

journal_title：Chinese medicine

authors： Tsai WJ,Chang CT,Wang GJ,Lee TH,Chang SF,Lu SC,Kuo YC

更新日期：2011-03-25 00:00:00

abstract：:Almost one in ten Australians has received acupuncture treatment by acupuncturists and/or medical doctors in private clinics. The majority of Australian health insurance funds offer rebates for acupuncture. Statutory regulations for acupuncture have been implemented in the State of Victoria, Australia. Six acupuncture...

journal_title：Chinese medicine

authors： Xue CC,Zhang AL,Yang AW,Zhang CS,Story DF

更新日期：2009-04-29 00:00:00

abstract：Background:Glycine tabacina (Labill.) Benth, one of the traditional Chinese herbal medicines, has been used for treatment of nephritis, osteoporosis, rheumatism, and menopausal syndrome. The aim of this study was to illuminate the therapeutic effect and mechanism of Glycine tabacina aqueous extract (GATE) in the treatm...

journal_title：Chinese medicine

authors： Tan L,Tu Y,Wang K,Han B,Peng H,He C

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Angelicae Sinensis Radix (ASR) and Chuanxiong Rhizoma (CR) can be treated with wine to promote their biological functions in Chinese medicine. Both ASR and CR contain similar volatile chemicals that could be altered after wine treatment. This study aims to identify the differential chemical profiles and to s...

journal_title：Chinese medicine

authors： Zhan JY,Zhang WL,Zheng KY,Zhu KY,Chen JP,Chan PH,Dong TT,Choi RC,Lam H,Tsim KW,Lau DT

更新日期：2013-06-06 00:00:00

abstract：BACKGROUND:Chrysin (5,7-dihydroxyflavone) inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation and arterial intima hyperplasia. This study aims to investigate the effects of chrysin on rat pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension (PH). METHODS:Sprague...

journal_title：Chinese medicine

authors： Li XW,Wang XM,Li S,Yang JR

更新日期：2015-02-18 00:00:00

abstract：Background:Investigation of aged Chinese herbal materials will help us to understand their use and sources in ancient time and broaden the historical perspective of Chinese material medica. To reach this aim, the basic understanding of aged herbal materials, including physical and chemical characters, is of great impor...

journal_title：Chinese medicine

authors： Jia Y,Sun M,Shi Y,Zhu Z,van Wijk E,van Wijk R,van Andel T,Wang M

更新日期：2020-01-15 00:00:00

abstract：BACKGROUND:Radix Polygoni Multiflori is the dried root tuber of Polygonum multiflorum Thunb. (Fam. Polygonaceae). According to Chinese medicine theory, raw (R-RPM) and processed (P-RPM) Radix Polygoni Multiflori possess different properties. The present study investigates the differences in chemistry between raw and pr...

journal_title：Chinese medicine

authors： Liang Z,Chen H,Yu Z,Zhao Z

更新日期：2010-08-12 00:00:00

abstract：BACKGROUND:Erxian decoction (EXD) is used to treat menopause-related symptoms in Chinese medicine. This study aims to identify the bioactive compounds and potential actions of EXD by network pharmacological analysis. METHODS:Two databases, the Traditional Chinese Medicine Systems Pharmacology database and TCM Database...

journal_title：Chinese medicine

authors： Wang S,Tong Y,Ng TB,Lao L,Lam JK,Zhang KY,Zhang ZJ,Sze SC

更新日期：2015-07-19 00:00:00

abstract：UNLABELLED: BACKGROUND:With the gaining popularity of commercially prepared decoctions of herbal medicines on the market, an objective and efficient way to reveal the authenticity of such products is urgently needed. Previous attempts to use chromatographic or spectroscopic methods to identify ginseng samples made use...

journal_title：Chinese medicine

authors： Chan PH,Zheng KY,Tsim KW,Lam H

更新日期：2012-11-12 00:00:00

abstract：BACKGROUND:The processed roots of Polygonum multiflorum Thunb. (Heshouwu; processed HSW) are commonly used in anti-aging medicine. Few reports have combined chemical profiles with bioactivity to evaluate the quality of the processed HSW. This study aims to integrate chemometric fingerprints of antioxidant activities an...

journal_title：Chinese medicine

authors： Chen HF,Chen YH,Liu CH,Wang L,Chen X,Yu BY,Qi J

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:There is a long history of coronary heart disease (CHD) diagnosis and treatment in Chinese medicine (CM), but a formalized description of CM knowledge is still unavailable. This study aims to analyze a set of CM clinical data, which is important and urgent. METHODS:Relative associated density (RAD) was used...

journal_title：Chinese medicine

authors： Li GZ,Sun S,You M,Wang YL,Liu GP

更新日期：2012-04-05 00:00:00

abstract：Background:Chronic alcohol consumption disrupts psychomotor and cognitive functions, most of which are subserved by the dysfunction of hippocampus. Dysregulated excitatory glutamatergic transmission is implicated in repeated alcohol induced psychomotor and cognitive impairment. Ginsenoside Rg1, one of the main active i...

journal_title：Chinese medicine

authors： Huang L,Peng Z,Lu C,Chen Y,Lv JW,Qin M,Liao DF,Liu XM,Shi Z

更新日期：2020-05-07 00:00:00

abstract：Background:Bacterial endophytes are widespread inhabitants inside plant tissues that play crucial roles in plant growth and biotransformation. This study aimed to offer information for the exploitation of endophytes by analyzing the bacterial endophytes in different parts of Panax notoginseng. Methods:We used high-thr...

journal_title：Chinese medicine

authors： Dong L,Cheng R,Xiao L,Wei F,Wei G,Xu J,Wang Y,Guo X,Chen Z,Chen S

更新日期：2018-08-14 00:00:00

abstract：Background:Autism spectrum disorders (ASD) is a common disease and the incidence has been rising constantly. Acupuncture is one of the most widely used complementary and alternative medicine therapies. Despite studies had been done on the effectiveness of acupuncture on ASD children, how factors such as chronological a...

journal_title：Chinese medicine

authors： Yau CH,Ip CL,Chau YY

更新日期：2018-06-15 00:00:00

abstract：UNLABELLED: BACKGROUND:Some Chinese herbs contain several kinds of phytoestrogens, and these herbs are commonly prescribed in Taiwan. Phytoestrogens may influence the effects of estrogen in females, although their activities are weak. This study aims to identify the risk and analyze the prescription profile of commonl...

journal_title：Chinese medicine

authors： Wu CT,Tzeng JN,Lai JN,Tsan SH,Wang JD

更新日期：2012-10-16 00:00:00

abstract：Background:Leflunomide (LEF) is a first-line disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, there are still a few nonresponders. It is logical to suggest that employing combinations including LEF that produce synergistic effects in terms of pharmacological activity is a promising s...

journal_title：Chinese medicine

authors： Zhang C,Guan D,Jiang M,Liang C,Li L,Zhao N,Zha Q,Zhang W,Lu C,Zhang G,Liu J,Lu A

更新日期：2019-08-02 00:00:00

abstract：BACKGROUND:Herba Cistanches (Roucongrong) is effective in treating Shenxu Zheng ('kidney-deficiency syndrome'). However, the mechanisms and systemic metabolic responses to the herbal intervention are unclear. METHODS:Using GC-MS-based metabolic profiling, we investigated the metabolic responses to Herba Cistanches int...

journal_title：Chinese medicine

authors： Qiu Y,Chen M,Su M,Xie G,Li X,Zhou M,Zhao A,Jiang J,Jia W

更新日期：2008-03-10 00:00:00

abstract：Background:Panax notoginseng is a highly valuable medicinal plant. Reduced P. notoginseng yield is a common and serious problem that arises in a continuous cropping system. Variation in the composition and function of soil microbial community is considered the primary cause of yield reduction. Methods:This study used ...

journal_title：Chinese medicine

authors： Li M,Chen Z,Qian J,Wei F,Zhang G,Wang Y,Wei G,Hu Z,Dong L,Chen S

更新日期：2020-08-10 00:00:00