Differential proteomics for studying action mechanisms of traditional Chinese medicines.

abstract：UNLABELLED: BACKGROUND:With the gaining popularity of commercially prepared decoctions of herbal medicines on the market, an objective and efficient way to reveal the authenticity of such products is urgently needed. Previous attempts to use chromatographic or spectroscopic methods to identify ginseng samples made use...

journal_title：Chinese medicine

authors： Chan PH,Zheng KY,Tsim KW,Lam H

更新日期：2012-11-12 00:00:00

abstract：Background:Biqi capsule is a traditional Chinese medicine widely used as a complementary and alternative treatment for rheumatoid arthritis (RA). The objective is to understand the efficacy, safety and mechanism of Biqi combined with methotrexate (MTX) in RA. Methods:We present a randomized, controlled pilot trial on ...

journal_title：Chinese medicine

authors： Wang Z,Wu J,Li D,Tang X,Zhao Y,Cai X,Chen X,Chen X,Huang Q,Huang R

更新日期：2020-04-23 00:00:00

abstract：Background:Investigation of aged Chinese herbal materials will help us to understand their use and sources in ancient time and broaden the historical perspective of Chinese material medica. To reach this aim, the basic understanding of aged herbal materials, including physical and chemical characters, is of great impor...

journal_title：Chinese medicine

authors： Jia Y,Sun M,Shi Y,Zhu Z,van Wijk E,van Wijk R,van Andel T,Wang M

更新日期：2020-01-15 00:00:00

abstract：Background:Glycine tabacina (Labill.) Benth, one of the traditional Chinese herbal medicines, has been used for treatment of nephritis, osteoporosis, rheumatism, and menopausal syndrome. The aim of this study was to illuminate the therapeutic effect and mechanism of Glycine tabacina aqueous extract (GATE) in the treatm...

journal_title：Chinese medicine

authors： Tan L,Tu Y,Wang K,Han B,Peng H,He C

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:HerboChip is an array of different fractions deriving from herbal extracts. This study aimed to identify effective components from Chinese medicine (CM) that interact with nerve growth factor (NGF) as a target using HerboChip. METHODS:Fifty types of CM that are traditionally used as remedies for emotion imb...

journal_title：Chinese medicine

authors： Lee PS,Zhang LM,Yan AL,Lam KY,Dong TT,Lin H,Chan GK,Tsim KW

更新日期：2016-07-23 00:00:00

abstract：:Almost one in ten Australians has received acupuncture treatment by acupuncturists and/or medical doctors in private clinics. The majority of Australian health insurance funds offer rebates for acupuncture. Statutory regulations for acupuncture have been implemented in the State of Victoria, Australia. Six acupuncture...

journal_title：Chinese medicine

authors： Xue CC,Zhang AL,Yang AW,Zhang CS,Story DF

更新日期：2009-04-29 00:00:00

abstract：BACKGROUND:The role of "Jun-Chen-Zuo-Shi" (also known as "sovereign-minister-assistant-courier") component herbs of Chinese medicine is not fully understood. This study aims to test the "Jun-Chen-Zuo-Shi" rule with the QiShenYiQi formula (QSYQ) on treating acute myocardial ischemia (AMI) by a network pharmacology appro...

journal_title：Chinese medicine

authors： Wu L,Wang Y,Li Z,Zhang B,Cheng Y,Fan X

更新日期：2014-09-16 00:00:00

abstract：BACKGROUND:KHU14, an ethanolic extract of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) was tested for its anti-inflammatory effects. METHODS:Three out of 20 herbs were found to have anti-inflammatory effects. The formulation of these herbs, i.e. KHU1...

journal_title：Chinese medicine

authors： Kim KS,Rhee HI,Park EK,Jung K,Jeon HJ,Kim JH,Yoo H,Han CK,Cho YB,Ryu CJ,Yang HI,Yoo MC

更新日期：2008-09-02 00:00:00

abstract：Background:Panax notoginseng is a highly valuable medicinal plant. Reduced P. notoginseng yield is a common and serious problem that arises in a continuous cropping system. Variation in the composition and function of soil microbial community is considered the primary cause of yield reduction. Methods:This study used ...

journal_title：Chinese medicine

authors： Li M,Chen Z,Qian J,Wei F,Zhang G,Wang Y,Wei G,Hu Z,Dong L,Chen S

更新日期：2020-08-10 00:00:00

abstract：BACKGROUND:Quantitative real-time reverse transcription PCR (qRT-PCR) requires a stable internal control to avoid misinterpretation of data or errors for gene expression normalization. However, there are still no validated reference genes for stable internal control in Poria cocos (Schw.) Wolf (Fuling). This study aims...

journal_title：Chinese medicine

authors： Zhang X,Xu ZC,Xu J,Ji AJ,Luo HM,Song JY,Sun C,Hu YL,Chen SL

更新日期：2016-03-02 00:00:00

abstract：Background:To evaluate the effects of Huang Bai (Phellodendron amurense) on growth and maturation in adolescent female rats. Methods:Female Sprague-Dawley rats (28 days old; n = 72) were divided into six daily treatment groups: control (distilled water), Huang Bai (100 and 300 mg/kg), recombinant human GH (rhGH; 20 μg...

journal_title：Chinese medicine

authors： Lee SH,Lee HJ,Lee SH,Kim YS,Lee D,Chun J,Lee JY,Kim H,Chang GT

更新日期：2018-01-12 00:00:00

abstract：Background:Chinese herbs have been widely used for thousands of years. In order to kill or control insects and fungus during the cultivation of herb plants, pesticides have played a significant role. More than 30 kinds of pesticides have been documented in the latest version of Chinese Pharmacopoeia. It is urgent to de...

journal_title：Chinese medicine

authors： Wei J,Xue Y,Dong J,Wang S,Hu H,Gao H,Li P,Wang Y

更新日期：2020-03-10 00:00:00

abstract：: Variable results of pain alleviation in response to acupuncture have been reported, complicating its interpretation. Sources of variability are probably multi-factorial, including the contribution of gender related effects. Gender related variation in perceived pain has been discussed frequently, but documented effec...

journal_title：Chinese medicine

authors： Lund I,Lundeberg T

更新日期：2010-09-04 00:00:00

abstract：BACKGROUND:Radix Wikstroemiae is a common Chinese herbal medicine. The ethyl acetate fraction of the ethanolic extract of W. indica possesses potent in vitro antiviral activity against respiratory syncytial virus (RSV). This study aims to identify the antiviral components of the active fraction. METHODS:The active fra...

journal_title：Chinese medicine

authors： Huang W,Zhang X,Wang Y,Ye W,Ooi VE,Chung HY,Li Y

更新日期：2010-06-21 00:00:00

abstract：Background:Bushen Huoxue decoction (BHD) has a significant effect on fracture rehabilitation, yet its underlying mechanism is still unknown. The purpose of this study was to explore whether BHD promotes bone marrow mesenchymal stem cell (BMSC) migration through the Wnt5a signalling pathway. Methods:BHD was extracted b...

journal_title：Chinese medicine

authors： Shen W,Luo H,Xu L,Wu Z,Chen H,Liu Y,Yu L,Hu L,Wang B,Luo Y

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:Eight medicinal plants were tested for their antimicrobial and antioxidant activities. Different extraction methods were also tested for their effects on the bioactivities of the medicinal plants. METHODS:Eight plants, namely Herba Polygonis Hydropiperis (Laliaocao), Folium Murraya Koenigii (Jialiye), Rhizo...

journal_title：Chinese medicine

authors： Chan LW,Cheah EL,Saw CL,Weng W,Heng PW

更新日期：2008-11-28 00:00:00

abstract：BACKGROUND:The edible endosperm of Lodoicea maldivica with the common name of coco de mer is used in Chinese medicine for treating cough. Native to Seychelles, Lodoicea maldivica seeds have commanded high prices for centuries due to its scarcity. This study aims to develop a molecular identification method for the auth...

journal_title：Chinese medicine

authors： Mak CY,Mok CS

更新日期：2011-09-30 00:00:00

abstract：Background:"Jinchuang ointment" is a traditional Chinese herbal medicine for external incised wounds. This herbal medicine has been successfully used to treat patients with diabetic foot ulcers and pressure sores in Taiwan for several decades. We previously examined its biological activities on cell-based in vitro assa...

journal_title：Chinese medicine

authors： Ho TJ,Chen JK,Li TS,Lin JH,Hsu YH,Wu JR,Tsai WT,Chen HP

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Aikeqing (AKQ) has been shown in clinical studies to improve quality of life of HIV/AIDS patients, but anti-HIV activity has not been determined. The SHIV-infected macaque is an important animal model for testing antiviral drugs. This study aimed to determine the anti-HIV activity of AKQ in chronically SHIV8...

journal_title：Chinese medicine

authors： Zhang GH,Han JB,Zhu L,Luo RH,Zhang XH,Chen X,Hu YJ,Fu LC,Zheng YT

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:QiXueHe Capsule (QXHC) is a Chinese patent drug that is extensively used for the treatment of menstrual disorders. However, its underlying pharmacological mechanisms have not been fully elucidated. METHODS:A list of QXHC putative targets were predicted using MetaDrug. An interaction network using links betw...

journal_title：Chinese medicine

authors： Zhang Y,Mao X,Su J,Geng Y,Guo R,Tang S,Li J,Xiao X,Xu H,Yang H

更新日期：2017-08-21 00:00:00

abstract：Background:Chemotherapy-induced nausea and vomiting (CINV) is a common and distressing side effect. We conducted this clinical trial to compare the effectiveness of true acupuncture vs. sham acupuncture in controlling chemotherapy-induced nausea and vomiting (CINV) among patients with advanced cancer. Methods:A total ...

journal_title：Chinese medicine

authors： Li QW,Yu MW,Wang XM,Yang GW,Wang H,Zhang CX,Xue N,Xu WR,Zhang Y,Cheng PY,Yang L,Fu Q,Yang Z

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:Yunu-Jian (YJ) is a Chinese medicine (CM) heat purging formula, which is used to reduce wei huo (stomach-heat, SH) and enrich shen yin (kidney-yin, KY). This formula is also commonly used to manage diabetes mellitus and gum/oral inflammation. The activity of YJ can be modified or refined by the addition of o...

journal_title：Chinese medicine

authors： Zee KY,Chan PS,Ho JCS,Lai SML,Corbet EF,Leung WK

更新日期：2016-09-20 00:00:00

abstract：BACKGROUND:Cellular redox state is important to cell growth and death. The growth of tumor cells may be modulated by intracellular reduced glutathione/oxidized glutathione (GSH/GSSG). The present study aims to investigate the effects of ginsenosides Re and Rg3 on cellular redox state and cell proliferation in C6 glioma...

journal_title：Chinese medicine

authors： Ng WY,Yang MS

更新日期：2008-07-11 00:00:00

abstract：:Inflammation is an active defense response of the body against external stimuli. Long term low-grade inflammation has been considered as a deteriorated factor for aging, cancer, neurodegeneration and metabolic disorders. The clinically used glucocorticoids and non-steroidal anti-inflammatory drugs are not suitable for...

journal_title：Chinese medicine

authors： Feng Z,Cao J,Zhang Q,Lin L

更新日期：2020-12-09 00:00:00

abstract：Background:Quality by design (QbD) is an advanced drug quality control concept that has been gradually implemented in the optimization of manufacturing processes of Chinese medicines. However, the variation of Chinese medicinal material quality has rarely been considered in published works. Because manufacturing proces...

journal_title：Chinese medicine

authors： Pan J,He S,Zheng J,Shao J,Li N,Gong Y,Gong X

更新日期：2019-09-24 00:00:00

abstract：Background:Leflunomide (LEF) is a first-line disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, there are still a few nonresponders. It is logical to suggest that employing combinations including LEF that produce synergistic effects in terms of pharmacological activity is a promising s...

journal_title：Chinese medicine

authors： Zhang C,Guan D,Jiang M,Liang C,Li L,Zhao N,Zha Q,Zhang W,Lu C,Zhang G,Liu J,Lu A

更新日期：2019-08-02 00:00:00

abstract：: One of the biggest obstacles to progress in modern pharmaceutical research is the difficulty of integrating all available research findings into effective therapies for humans. Studies of traditionally used pharmacologically active plants and other substances in traditional medicines may be valuable sources of previo...

journal_title：Chinese medicine

authors： Samwald M,Dumontier M,Zhao J,Luciano JS,Marshall MS,Cheung K

更新日期：2010-12-17 00:00:00

abstract：Background:Autism spectrum disorders (ASD) is a common disease and the incidence has been rising constantly. Acupuncture is one of the most widely used complementary and alternative medicine therapies. Despite studies had been done on the effectiveness of acupuncture on ASD children, how factors such as chronological a...

journal_title：Chinese medicine

authors： Yau CH,Ip CL,Chau YY

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:The processed roots of Polygonum multiflorum Thunb. (Heshouwu; processed HSW) are commonly used in anti-aging medicine. Few reports have combined chemical profiles with bioactivity to evaluate the quality of the processed HSW. This study aims to integrate chemometric fingerprints of antioxidant activities an...

journal_title：Chinese medicine

authors： Chen HF,Chen YH,Liu CH,Wang L,Chen X,Yu BY,Qi J

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:Chronic non-specific low back pain (LBP) is a prevalent (80%) and multi-dimensional illness. This study aims to test whether acupuncture, baclofen, or combined treatment with acupuncture and baclofen alleviates symptoms of non-specific chronic LBP in men. METHODS:Eight-four (84) men aged 50-60 years with no...

journal_title：Chinese medicine

authors： Zaringhalam J,Manaheji H,Rastqar A,Zaringhalam M

更新日期：2010-04-24 00:00:00