Abstract:
Background:Chemotherapy-induced nausea and vomiting (CINV) is a common and distressing side effect. We conducted this clinical trial to compare the effectiveness of true acupuncture vs. sham acupuncture in controlling chemotherapy-induced nausea and vomiting (CINV) among patients with advanced cancer. Methods:A total of 134 participants were randomly allocated into true acupuncture (TA) (n = 68) and sham acupuncture (SA) (n = 66) groups. Participants in both groups received acupuncture session twice on the first day of chemotherapy, and once consecutively on the following 4 days. The primary outcome was using the Common Terminology Criteria for Adverse Events (CTCAE) to assess CINV. The secondary outcome measures were the Eastern Cooperative Oncology Group score (ECOG), Simplified Nutritional Appetite Questionnaire (SNAQ), and Hospital Anxiety and Depression scale (HADS). Results:Compared to the SA group, the TA group didn't show significant improvement in complete response rates of chemotherapy-induced nausea and vomiting (all P > 0.05). However, the TA group could modestly reduce the severity of nausea (from day-3 to day-21, P < 0.05) or vomiting (from day-4 to day-21, P < 0.05), which is notably superior to the control group. Besides, TA promoted the nutritional status of patients with a significantly higher score comparing to the SA group on day 14 (21.82 vs.20.12, P = 0.003) and day 21 (22.39 vs. 20.43, P = 0.001). No apparent differences were found in anxiety and depression assessment between these groups. Participants in both groups were well tolerant of acupuncture therapy. There was no adverse event occurs in our study. Conclusion:Acupuncture as an adjunctive approach could alleviate the severity of chemotherapy-induced nausea and vomiting compared to the sham control, even though the effect of acupuncture in preventing CINV occurring is relatively modest.
journal_name
Chin Medjournal_title
Chinese medicineauthors
Li QW,Yu MW,Wang XM,Yang GW,Wang H,Zhang CX,Xue N,Xu WR,Zhang Y,Cheng PY,Yang L,Fu Q,Yang Zdoi
10.1186/s13020-020-00333-xsubject
Has Abstractpub_date
2020-06-03 00:00:00pages
57issn
1749-8546pii
333journal_volume
15pub_type
杂志文章相关文献
Chinese Medicine文献大全abstract:BACKGROUND:Yunu-Jian (YJ) is a Chinese medicine (CM) heat purging formula, which is used to reduce wei huo (stomach-heat, SH) and enrich shen yin (kidney-yin, KY). This formula is also commonly used to manage diabetes mellitus and gum/oral inflammation. The activity of YJ can be modified or refined by the addition of o...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-016-0111-z
更新日期:2016-09-20 00:00:00
abstract:BACKGROUND:Angelicae Sinensis Radix (ASR) and Chuanxiong Rhizoma (CR) can be treated with wine to promote their biological functions in Chinese medicine. Both ASR and CR contain similar volatile chemicals that could be altered after wine treatment. This study aims to identify the differential chemical profiles and to s...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-8-12
更新日期:2013-06-06 00:00:00
abstract:Background:Leflunomide (LEF) is a first-line disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, there are still a few nonresponders. It is logical to suggest that employing combinations including LEF that produce synergistic effects in terms of pharmacological activity is a promising s...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-019-0247-8
更新日期:2019-08-02 00:00:00
abstract:: Herbal ingredients in a Chinese fufang prescription are often replaced by one or several other herbal combinations. As there have been very few Chinese herbal patent infringement cases, it is still unclear how the Doctrine of Equivalents should be applied to determine the scope of 'equivalents' in Chinese fufang pres...
journal_title:Chinese medicine
pub_type: 社论
doi:10.1186/1749-8546-6-30
更新日期:2011-08-19 00:00:00
abstract:BACKGROUND:Few health measurement scales are based on Chinese medicine theory. The Health Scale of Traditional Chinese Medicine (HSTCM) was developed to fill this gap. The aim of this study is to validate the HSTCM. METHODS:A convenience sample of 630 participants was recruited in 11 settings. All participants were as...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-4-8
更新日期:2009-04-30 00:00:00
abstract:BACKGROUND:Chrysin (5,7-dihydroxyflavone) inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation and arterial intima hyperplasia. This study aims to investigate the effects of chrysin on rat pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension (PH). METHODS:Sprague...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-015-0032-2
更新日期:2015-02-18 00:00:00
abstract:Background:Herbal materials are widely used as medicinal products, dietary supplements, food, and spices. With increased consumption, the safety, quality, and efficacy of herbal materials are becoming more relevant. The authenticity of herbal materials plays an important role in herbal quality control, and there is an ...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-019-0269-2
更新日期:2019-10-28 00:00:00
abstract:BACKGROUND:The processed roots of Polygonum multiflorum Thunb. (Heshouwu; processed HSW) are commonly used in anti-aging medicine. Few reports have combined chemical profiles with bioactivity to evaluate the quality of the processed HSW. This study aims to integrate chemometric fingerprints of antioxidant activities an...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-016-0087-8
更新日期:2016-04-12 00:00:00
abstract:UNLABELLED: BACKGROUND:Some Chinese herbs contain several kinds of phytoestrogens, and these herbs are commonly prescribed in Taiwan. Phytoestrogens may influence the effects of estrogen in females, although their activities are weak. This study aims to identify the risk and analyze the prescription profile of commonl...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-7-22
更新日期:2012-10-16 00:00:00
abstract:Background:Autism spectrum disorders (ASD) is a common disease and the incidence has been rising constantly. Acupuncture is one of the most widely used complementary and alternative medicine therapies. Despite studies had been done on the effectiveness of acupuncture on ASD children, how factors such as chronological a...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-018-0189-6
更新日期:2018-06-15 00:00:00
abstract:BACKGROUND:Ganoderma sp., such as Ganoderma tsugae (GT), play an important role in traditional Chinese medicine. Ganoderma sp. contains several constituents, including Sacacchin, which has recently drawn attention because it can not only enhance the repair of muscle damage but also strengthen the muscle enforcement. Al...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-020-00381-3
更新日期:2020-09-22 00:00:00
abstract:: Active myofascial trigger points are one of the major peripheral pain generators for regional and generalized musculoskeletal pain conditions. Myofascial trigger points are also the targets for acupuncture and/or dry needling therapies. Recent evidence in the understanding of the pathophysiology of myofascial trigger...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-6-13
更新日期:2011-03-25 00:00:00
abstract:BACKGROUND:Qing-dai powder (QDP), comprising Indigo naturalis (Qing-dai) and dried alum (Ku-fan), was used in Chinese medicine to treat the conditions associated with mucosal hemorrhage, such as ulcerative colitis (UC). This study aims to investigate the effects and potential mechanism of QDP on dextran sulfate sodium ...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-015-0061-x
更新日期:2015-10-13 00:00:00
abstract:Background:Biqi capsule is a traditional Chinese medicine widely used as a complementary and alternative treatment for rheumatoid arthritis (RA). The objective is to understand the efficacy, safety and mechanism of Biqi combined with methotrexate (MTX) in RA. Methods:We present a randomized, controlled pilot trial on ...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-020-00319-9
更新日期:2020-04-23 00:00:00
abstract:Background:Bacterial endophytes are widespread inhabitants inside plant tissues that play crucial roles in plant growth and biotransformation. This study aimed to offer information for the exploitation of endophytes by analyzing the bacterial endophytes in different parts of Panax notoginseng. Methods:We used high-thr...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-018-0198-5
更新日期:2018-08-14 00:00:00
abstract:BACKGROUND:Aikeqing (AKQ) has been shown in clinical studies to improve quality of life of HIV/AIDS patients, but anti-HIV activity has not been determined. The SHIV-infected macaque is an important animal model for testing antiviral drugs. This study aimed to determine the anti-HIV activity of AKQ in chronically SHIV8...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-016-0105-x
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Chronic non-specific low back pain (LBP) is a prevalent (80%) and multi-dimensional illness. This study aims to test whether acupuncture, baclofen, or combined treatment with acupuncture and baclofen alleviates symptoms of non-specific chronic LBP in men. METHODS:Eight-four (84) men aged 50-60 years with no...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-5-15
更新日期:2010-04-24 00:00:00
abstract:BACKGROUND:KHU14, an ethanolic extract of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) was tested for its anti-inflammatory effects. METHODS:Three out of 20 herbs were found to have anti-inflammatory effects. The formulation of these herbs, i.e. KHU1...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-3-10
更新日期:2008-09-02 00:00:00
abstract::Almost one in ten Australians has received acupuncture treatment by acupuncturists and/or medical doctors in private clinics. The majority of Australian health insurance funds offer rebates for acupuncture. Statutory regulations for acupuncture have been implemented in the State of Victoria, Australia. Six acupuncture...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-4-7
更新日期:2009-04-29 00:00:00
abstract:UNLABELLED: BACKGROUND:With the gaining popularity of commercially prepared decoctions of herbal medicines on the market, an objective and efficient way to reveal the authenticity of such products is urgently needed. Previous attempts to use chromatographic or spectroscopic methods to identify ginseng samples made use...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-7-25
更新日期:2012-11-12 00:00:00
abstract:BACKGROUND:Zedoary (Curcumae Rhizoma, Ezhu), a Chinese medicinal herb, has been reported to show anticancer activity. This study aims to investigate the effect of zedoary oil (Ezhu You) on the proliferation of AGS cells which is one gastric cancer cell line. METHODS:The main ingredients of the herb were detected by GC...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-8-13
更新日期:2013-06-28 00:00:00
abstract:Background:Panax notoginseng is a highly valuable medicinal plant. Reduced P. notoginseng yield is a common and serious problem that arises in a continuous cropping system. Variation in the composition and function of soil microbial community is considered the primary cause of yield reduction. Methods:This study used ...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-020-00364-4
更新日期:2020-08-10 00:00:00
abstract:Background:Quality by design (QbD) is an advanced drug quality control concept that has been gradually implemented in the optimization of manufacturing processes of Chinese medicines. However, the variation of Chinese medicinal material quality has rarely been considered in published works. Because manufacturing proces...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-019-0262-9
更新日期:2019-09-24 00:00:00
abstract::Inflammation is an active defense response of the body against external stimuli. Long term low-grade inflammation has been considered as a deteriorated factor for aging, cancer, neurodegeneration and metabolic disorders. The clinically used glucocorticoids and non-steroidal anti-inflammatory drugs are not suitable for...
journal_title:Chinese medicine
pub_type: 杂志文章,评审
doi:10.1186/s13020-020-00407-w
更新日期:2020-12-09 00:00:00
abstract:Background:Glycine tabacina (Labill.) Benth, one of the traditional Chinese herbal medicines, has been used for treatment of nephritis, osteoporosis, rheumatism, and menopausal syndrome. The aim of this study was to illuminate the therapeutic effect and mechanism of Glycine tabacina aqueous extract (GATE) in the treatm...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-020-00361-7
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Triptolide, an active compound of Radix Tripterygium wilfordii, is immunosuppressive, cartilage protective and anti-inflammatory both in human and animal studies of various inflammatory and autoimmune diseases, including rheumatoid arthritis, but its therapeutic mechanism remains unclear. The aim of this stu...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-4-13
更新日期:2009-07-02 00:00:00
abstract:BACKGROUND:Erxian decoction (EXD) is used to treat menopause-related symptoms in Chinese medicine. This study aims to identify the bioactive compounds and potential actions of EXD by network pharmacological analysis. METHODS:Two databases, the Traditional Chinese Medicine Systems Pharmacology database and TCM Database...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-015-0051-z
更新日期:2015-07-19 00:00:00
abstract:BACKGROUND:The differentiation resp. death of human monocytic THP-1 cells induced by polysaccharide extracts of the medicinal mushrooms Phellinus linteus, Agaricus bisporus and Agaricus brasiliensis have been studied. This study aims to identify leads for the causal effects of these mushroom components on cell differen...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-8-25
更新日期:2013-12-18 00:00:00
abstract:BACKGROUND:QiXueHe Capsule (QXHC) is a Chinese patent drug that is extensively used for the treatment of menstrual disorders. However, its underlying pharmacological mechanisms have not been fully elucidated. METHODS:A list of QXHC putative targets were predicted using MetaDrug. An interaction network using links betw...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/s13020-017-0145-x
更新日期:2017-08-21 00:00:00
abstract:BACKGROUND:Cellular redox state is important to cell growth and death. The growth of tumor cells may be modulated by intracellular reduced glutathione/oxidized glutathione (GSH/GSSG). The present study aims to investigate the effects of ginsenosides Re and Rg3 on cellular redox state and cell proliferation in C6 glioma...
journal_title:Chinese medicine
pub_type: 杂志文章
doi:10.1186/1749-8546-3-8
更新日期:2008-07-11 00:00:00