[Development and first results of fast and cost-effective examination methods for an ophthalmological screening within the National Cohort].

Abstract:

BACKGROUND:For an implemented ophthalmological screening within a German long-term cohort study (National Cohort) simple and effective methods for an examination of visual acuity and for non-mydriatic retina photografies should be evaluated. Furthermore standard operating-procedures (SOP) should be developed. METHODS:In the years 2011 and 2012 pinhole visual acuity measurements and automated retina photographies (DRS, CenterVue S. p. a., Padua, Italy) were made at three different epidemiological study centers within Germany. Furthermore, anterior segment images were taken by the camera. Standard operating procedures (SOP) regarding the ophthalmological screening were developed and evaluated within the study. The main question was whether it is possible to implement the screening methods within the National Cohort. Further main outcomes were quality and interpretability of the taken images. RESULTS:457 subjects (914 eyes) were examined within the investigation. Median VA was 0.8 for right and left eyes (p > 0.42). Image quality of the photographies was good in 491 cases (54 %), fair in 239 cases (26 %) and bad in 179 cases (20 %). The usability of the images was without limitations in 686 cases (75 %), limited in 152 cases (17 %) and not given in 71 cases (8 %). Increasing age of the subjects was slightly correlated with decreasing image quality (r = 0.26) and decreasing image usability (r = 0.2). Anterior segment photographies were usable in 176 eyes (56 %). CONCLUSION:The developed screening method fulfilled the specifications of the National Cohort. The used pinhole visual acuity examination was fast and cheap. Image quality and usability of the retina photographies could be improved with prolonged pupil recovery times. The quality of the anterior segment images could not fulfill the expectations and were taken out of the further examinations of the ophthalmological screening. The written SOP showed good acceptance within the investigators' daily routine. The ophthalmological screening within the National Cohort generates information (e. g., pathologies of the vessels or of the retina) which are useful not only from an ophthalmological point of view.

journal_name

Klin Monbl Augenheilkd

authors

Leitritz MA,Hense HW,Schiefer U,Nagel M,Greiser H,Linseisen J,Heid I,Fischer B,Thierry S,Bartz-Schmidt KU,Ueffing M

doi

10.1055/s-0033-1350685

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

1238-46

issue

12

eissn

0023-2165

issn

1439-3999

journal_volume

230

pub_type

杂志文章,多中心研究
  • [Malignancies in relatives of retinoblastoma patients (author's transl)].

    abstract::In 14 out of 25 patients with retinoblastoma there was a family history of malignancies. Most of the malignant tumours had been carcinomas. In 2 families relatives died because of leukaemia; in these cases the tumour was a so-called diffuse retinoblastoma occurring in elder children. A third family with a retinoblasto...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Stefani FH

    更新日期:1976-05-01 00:00:00

  • [Near heterophoria with a description of the heterometer].

    abstract::The examination of near heterophoria with a heterometer using a large series of test plates presented "free-sighted" (i.e., not hindered by optical or mechanical means) enables a more comprehensive analysis to be made than has so far been achieved with other instruments. The principal components of the instruments are...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050156

    authors: Littan KE

    更新日期:1988-05-01 00:00:00

  • [Observations on cataract incision dehiscence (author's transl)].

    abstract::24 patients with rupturing corneal incisions were observed within 6 years from 1971 until 1976. 19 patients had already had cataract extractions performed by us. This complication occurred in 0.5% of cases. All ruptures were investigated regarding the period of time after the cataract extraction, and possible precipit...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Bleckmann H

    更新日期:1977-05-01 00:00:00

  • [Alternate day squint (author's transl)].

    abstract::3 cases of cyclical convergent strabismus (48 hour rhythm) were investigated. In contrast to intermittant strabismus, cyclical strabismus is not fatigue dependant. An alteration in the rhythm of the cyclical esotropia was produced by wearing prisms, red glasses or occlusion for several days. This observation indicates...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Schmidt D,Mattheus S

    更新日期:1975-12-01 00:00:00

  • [Eyelid Tumors: Clinical Aspects of Ophthalmic Pathology].

    abstract:BACKGROUND:Lid tumors show a heterogenous clinical spectrum. Tumors which display some criteria of malignancy may histologically be diagnosed as inflammatory lesions without any neoplastic component. In contrast, malignant tumors can induce changes on the lid margin mimicking inflammatory changes. MATERIAL AND METHODS...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/a-0633-3120

    authors: Herwig-Carl MC,Löffler KU

    更新日期:2018-07-01 00:00:00

  • [Pars plana vitrectomy in proliferative diabetic retinopathy].

    abstract::In this contribution the authors present the results of treatment by pars plana vitrectomy in a consecutive series of 200 patients with proliferative retinopathy. Anatomical success was achieved in 82% of the cases of simple vitreous hemorrhages, in 63% and 67% respectively of the cases of traction detachment with or ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050630

    authors: Krampitz-Glaas G,Laqua H

    更新日期:1986-04-01 00:00:00

  • [Bilateral pigmented epi- and submacular membrane].

    abstract:PURPOSE:The aim of this communication is to report a case of epiretinal membrane removal with intra-operative unexpected subretinal extension of the membrane. METHODS:This is an observational case report. An 83-year-old female patient with bilateral pigmented secondary macular pucker after laser coagulation for diabet...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1027237

    authors: Steven P,Klinger M,Hoerauf H

    更新日期:2008-03-01 00:00:00

  • [Parapapillary autofluorescence as indicator for glaucoma].

    abstract:BACKGROUND:A pronounced fundus autofluorescence (lipofuscin) occurs in eyes with AMD. Parapapillary lipofuscin accumulation in the retinal pigment epithelial cells was observed in eyes with advanced glaucoma histologically. The aim of this study was to evaluate the parapapillary autofluorescence (PAF) in vivo in health...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858856

    authors: Viestenz A,Langenbucher A,Mardin CY

    更新日期:2006-04-01 00:00:00

  • [Diagnosis and treatment of intraocular tumors in the child].

    abstract:PURPOSE:To remind of the absolute necessity for early diagnosis in the presence of ocular signs in children giving rise to possible intraocular tumours. METHOD:Based on our own experience of intraocular tumours in children, together with findings from the literature, diagnostic criteria and methods of treatment are pr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2001-15884

    authors: Balmer A,Munier F

    更新日期:2001-05-01 00:00:00

  • [Perimetric diagnosis of chiasmal injury after contusion of skull and brain (author's transl)].

    abstract::After a discussion of the pathomechanism of skull trauma by a blow leading to chiasmal lesion, frontobasal injuries of the skull are considered; it is shown that typical defects of the visual field resulting from chiasmal damage can be revealed not only in cases of serious industrial or traffic accidents with brain co...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Fulmek R

    更新日期:1976-11-01 00:00:00

  • [The 30 prism test].

    abstract::The 30-prism-test is a relatively quick and simple method for many-sided testing binocular behaviour in near distance in patients with reading difficulties and asthenopic symptoms, respecting well known and assumed causes of the disturbances. Therefore indications for treatment are given. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035556

    authors: Safra D

    更新日期:1994-05-01 00:00:00

  • [Micro-perimetric documentation of retinal function in photodynamic therapy of choroid neovascularizations].

    abstract:PURPOSE:Photodynamic therapy provides occlusion of choroidal neovascularization by intravascular endothelial damage. The photodynamic approach offers the potential to occlude choroidal neovascularization selectively without altering adjacent sensory retina and therefore to preserve visual acuity. To determine the selec...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2000-10537

    authors: Bunse A,Elsner H,Laqua H,Schmidt-Erfurth U

    更新日期:2000-03-01 00:00:00

  • [Is timolol effective in neovascular glaucoma? (author's transl)].

    abstract::Timolol lowered intraocular pressure in six patients with severe neovascular glaucoma only from about 45 mmHg to about 38 mmHg. The intense pain suffered by five patients was not alleviated. Hence, Timolol treatment does not seem very effective in neovascular glaucoma, although it may be of some value as a supplement ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057639

    authors: Bischoff P,Speiser P

    更新日期:1980-01-01 00:00:00

  • [Determining the true size of an object on the fundus of the living eye].

    abstract::In a preceding paper with the same title the result was represented by curves which enable factors used in calculating the true diameter to be determined. Instead of the curves a quadratic equation is used to produce the same factors. The data for the equation are given in two tables. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050076

    authors: Littmann H

    更新日期:1988-01-01 00:00:00

  • [Surgical technical principles of trans-scleral suture of posterior chamber lenses].

    abstract:BACKGROUND:Most reports on transscleral suture fixation of posterior chamber lenses (PCL) do not mention the principal difficulty that the surgeon has no valid information which structures were perforated by the needle and where he happened to fix the PCL loops. To know this exactly is a "conditio sine qua non". Withou...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045599

    authors: Sundmacher R,Althaus C

    更新日期:1993-04-01 00:00:00

  • [High altitude retinal hemorrhages in mountain climbers (author's transl)].

    abstract::A report is given on three patients who noticed an acute deterioration of visual acuity after a sojourn at 5000 altitude caused by retinal hemorrhages. We documented both the ophthalmological examinations such as visual acuity, fundus, perimetry and fluorescence-angiography and the systemic results. During the period ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Vogt C,Greite JH,Hess J

    更新日期:1978-05-01 00:00:00

  • [Pyoderma vegetans of the eye-lid (author's transl)].

    abstract::A cases of Pyoderma vegetans attacking only the outer skin of the eyelid and leaving free the conjunctiva is reported. The diagnosis of this rare condition, belonging to the pemphigus diseases, depends on clinical course and especially on histological investigation. The aetiology of Pyoderma vegetans still remains unk...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Uthoff D,Teichmann KD,Pülhorn G

    更新日期:1978-08-01 00:00:00

  • [Basics for the Preparation of an Ophthalmological Expert Assessment].

    abstract::The position of the ophthalmologist as an unbiased and impartial expert in the field of tension between the client and the patient is a responsible task that should not be underestimated. Since the ophthalmological expert assessment often has far-reaching legal and financial consequences, it is very important that it ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-0889-9523

    authors: von Livonius B

    更新日期:2019-04-18 00:00:00

  • [Comparison of different optical techniques for determination of the dimensions of anterior ocular segment].

    abstract:BACKGROUND:The evaluation of the anterior ocular chamber sections along the optical axis/axis of vision has been carried out using single-line partial coherence interferometry for many years. Now, new technologies such as the Scheimpflug-technique of the Pentacam (Oculus Optikgeräte GmbH, Wetzlar) and the optical coher...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0028-1109367

    authors: Lange S,Haigis W,Grein HJ,Schütze J

    更新日期:2009-06-01 00:00:00

  • [Blepharophimosis syndrome. Clinical aspects and therapy].

    abstract::Symptoms, genetics and differential diagnosis of this rare, congenital deformity of the lids are described. Strategies for the conservative and surgical therapy on the basis of own experiences and an extensive review of the literature are presented. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1035418

    authors: Hintschich CR,Zürcher M

    更新日期:1995-03-01 00:00:00

  • [Results of 1-year use of local pindolol in open-angle glaucoma].

    abstract::In a randomized and controlled study (already published) the efficacy and safety of Pindolol eye drops 1% were compared with Timolol eye drops 0.5% in the treatment of open-angle glaucoma over a period of 6 months. With the exception of some allergic reactions there was no difference between the two with regard to IOP...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050872

    authors: Stryz JR,Merté HJ

    更新日期:1985-01-01 00:00:00

  • [Ocular involvement in MuSK antibody-positive myasthenia gravis].

    abstract:BACKGROUND:Antibodies (Ab) against the acetylcholine receptor (AChR) are found in 80 - 90 % of generalized myasthenia gravis (MG), but only in 50 % of pure ocular MG. Furthermore, Ab against the muscle-specific receptor tyrosine kinase (MuSK) were detected in 38 - 54 % of patients with AChR-Ab-negative ("seronegative")...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858629

    authors: Bau V,Hanisch F,Hain B,Zierz S

    更新日期:2006-01-01 00:00:00

  • [The anterior hyaloid membrane of the vitreous body in congenital ectopic lens].

    abstract::Congenital, bilaterally symmetrical dislocation of the lens within the posterior chamber is referred to as lens ectopia. The behavior of the anterior hyaloid membrane in congenital lens ectopia has not been considered hitherto. The anterior hyaloid membrane in the aphakic area of the pupil is intact or ruptured and th...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050519

    authors: Slezak H,Arocker-Mettinger E

    更新日期:1987-11-01 00:00:00

  • [The clinical picture, fluorescence angiography and histologie of a ringmelanoma of the iris (author's transl)].

    abstract::Report on a rare case of an iris-ringmelanoma. Arising from the iris base the primary tumor spread in a continuous line along the anterior chamber angle and a shedding of tumor cells in other places of the iris surface could be stated as well. A unilateral dark spotted colouring of the iris with a secondary glaucoma w...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Demeler U,von Domarus D

    更新日期:1976-03-01 00:00:00

  • [II: Difference plots or scattergram--when to use which?].

    abstract::Sometimes the statistical comparison of diagnostic measurement methods or subsequent measurement series in the same individuals is based on bivariate scattergrams; correlation coefficients and linear regression lines are provided in addition. However, this strategy for data representation must be considered inappropri...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-35165

    authors: Krummenauer F

    更新日期:2002-09-01 00:00:00

  • [The surprising finding and removal of a large plastic foreign body through the corneal wound from the vitreous cavity with good outcome].

    abstract:BACKGROUND:Presented is a patient whose history showed that during a hammer-blow on a piece of iron something had flown into his left eye. Clinical investigation revealed a 9-mm long, horizontal, paracentrally located, penetrating corneal wound. Temporally in the same region the iris was torn in its entire width. The l...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-857910

    authors: Gracner B,Pahor D,Gracner T,Falez M

    更新日期:2005-02-01 00:00:00

  • [Intraocular pressure and primary open-angle glaucoma. Epidemiologic technics in practice].

    abstract::It is the object of this paper to familiarize the ophthalmologist with some modern epidemiological techniques and to present examples of their application to a consideration of the influence of the level of intraocular pressure on the development of the type of visual field loss characteristic of primary open angle gl...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054461

    authors: Crick RP,Daubs JG

    更新日期:1984-04-01 00:00:00

  • Latanoprost is a vasoconstrictor in isolated porcine ciliary arteries.

    abstract:PURPOSE:The purpose of this study was to assess the vasoconstrictor effect of the prostaglandin F2 alpha analog latanoprost in isolated porcine ciliary arteries. MATERIAL AND METHODS:With a myograph system to measure isometric forces, porcine ciliary arteries were exposed, in a cumulative manner, to increasing concent...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2001-15904

    authors: Brogiolo G,Flammer J,Haefliger IO

    更新日期:2001-05-01 00:00:00

  • [Treatment of senile maculopathy with etaretin].

    abstract::The results of parenteral treatment with Etaretin in 40 patients (79 eyes) suffering from senile maculopathy are reported. In 84% of the cases there was a degeneration of the dry type and in 16% a disciform exudative maculopathy. The cases of dry maculopathy responded well within a floow-up period of 8 to 18 months. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050732

    authors: Varga M,Gábriel I,Follmann P

    更新日期:1986-06-01 00:00:00

  • [Modified moisture chamber].

    abstract:BACKGROUND:Moisture chambers can protect the eye in corneal lubrication or eyelid closure disorders. However, in cases with protrusio bulbi or pronounced chemosis conjunctivae direct damaging contact of the cornea or conjunctiva on the one hand and the inside of the moisture-chamber-bandage on the other hand are possib...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034745

    authors: Winter M,Kandzia C

    更新日期:1999-01-01 00:00:00