Strain Values of Left Ventricular Segments Reduce Non-homogeneously in Dilated Cardiomyopathy with Moderately and Severely Deteriorated Heart Function Assessed by MRI Tissue Tracking Imaging.

abstract：:microRNA-99a (miR-99a) is recently recognized as a key regulator in various cancers and cardiovascular diseases. In the present study, we sought to investigate the effects of miR-99a in rat cardiomyocyte H9c2 cells against oxidative injury induced by lipopolysaccharide (LPS).MTT assay, reactive oxygen species (ROS) as...

journal_title：International heart journal

authors： Jing R,Zhou Z,Kuang F,Huang L,Li C

更新日期：2017-05-31 00:00:00

abstract：:Prognosis of patients with heart failure (HF) remains unclear in Japan and should be determined in a prospective fashion. A prospective cohort of The Shinken Database comprised details on all of the new patients, including both inpatients and outpatients, who visited The Cardiovascular Institute Hospital in 2004-2005....

journal_title：International heart journal

authors： Goda A,Yamashita T,Suzuki S,Ohtsuka T,Uejima T,Oikawa Y,Yajima J,Koike A,Nagashima K,Kirigaya H,Sagara K,Ogasawara K,Isobe M,Sawada H,Aizawa T

更新日期：2009-09-01 00:00:00

abstract：:Various surgical techniques have been proposed for treating aortic arch aneurysm (AAA); however, the optimal treatment has not been well defined. This study introduces a new aortic arch inclusion technique with frozen elephant trunk (FET) for AAA treatment.A retrospective analysis was performed among 22 patients for A...

journal_title：International heart journal

authors： Zhu C,Piao H,Wang Y,Li B,Zhang Y,Xu J,Wang T,Zhu Z,Xu R,Li D,Liu K

更新日期：2020-11-28 00:00:00

abstract：:The factors responsible for the ST-T wave alternans (STTA) and associated arrhythmias during acute ischemia have not been clarified.In acutely ischemic porcine myocardium, we recorded transmural unipolar and bipolar electrocardiograms and mid-myocardial extracellular K(+) ([K(+)]e) from the center of the ischemic zone...

journal_title：International heart journal

authors： Watanabe I,Gettes LS

更新日期：2016-05-25 00:00:00

abstract：:Myocardial infarction (MI) occurs when the heart muscle is severely damaged due to a decrease in blood flow from the coronary arteries. During recovery from an MI, cardiac fibroblasts become activated and produce extracellular matrices, contributing to the wound healing process in the damaged heart. Inappropriate acti...

journal_title：International heart journal

authors： Wake M,Takeda N,Isagawa T,Sato T,Nakagama Y,Morioka MS,Hirota Y,Asagiri M,Maemura K,Manabe I,Tanabe K,Komuro I

更新日期：2019-07-27 00:00:00

abstract：:Patients with periodontal disease exhibit exacerbated atherosclerosis, aortic stiffness, or vascular endothelial dysfunction. However, in a recent scientific statement, the American Heart Association noted that neither has periodontal disease been proven to cause atherosclerotic vascular disease nor has the treatment ...

journal_title：International heart journal

authors： Hayashi S,Yamada H,Fukui M,Ito HO,Sata M

更新日期：2015-01-01 00:00:00

abstract：:Purulent pericarditis is a rare disease in the antibiotic era. The common pathogens of purulent pericarditis are gram-positive species such as Staphylococcus aureus. Streptococcus pneumoniae, Salmonella, Haemophilus, fungal pathogens/tuberculosis can also result in purulent pericarditis. We report an old male case of ...

journal_title：International heart journal

authors： Horii S,Yada H,Ito K,Osaki A,Sato A,Kimura T,Yasuda R,Toya T,Namba T,Masaki N,Adachi T

更新日期：2018-05-30 00:00:00

abstract：:This study aimed to evaluate the potential associations of intermediate monocytes (CD14(++)CD16(+)) with myocardial remodelling in ST segment elevation myocardial infarction (STEMI) patients with diabetes.A total of 67 STEMI patients with diabetes were enrolled. The control group consisted of 65 STEMI patients without...

journal_title：International heart journal

authors： Lu W,Zhang Z,Fu C,Ma G

更新日期：2015-01-01 00:00:00

abstract：:Acute aortic dissection (AAD) is a life-threatening cardiovascular disease with high mortality. Hypertension is a well known risk factor of AAD. There have been previous reports about the association between circadian variation of blood pressure (BP) and cardiovascular events. However, little is known about the associ...

journal_title：International heart journal

authors： Seguchi M,Wada H,Sakakura K,Nakagawa T,Ibe T,Ikeda N,Sugawara Y,Ako J,Momomura S

更新日期：2015-05-13 00:00:00

abstract：:The objective of the present prospective multicenter case-control study was to investigate the long-term clinical outcome (5 years) of primary stenting compared to primary percutaneous transluminal coronary angioplasty (PTCA) without stenting (POBA) in patients with acute myocardial infarction at 7 cardiovascular cent...

journal_title：International heart journal

authors： Sasao H,Tsuchihashi K,Nagao K,Miyamoto K,Murakami H,Doi A,Shimoshige S,Hasegawa K,Kyuma M,Noda R,Shimamoto K

更新日期：2006-01-01 00:00:00

abstract：:Exhaled acetone concentration is one of the expected compounds to be a breath biomarker in heart failure. However, it has not been clarified how exhaled acetone concentration changes in clinical course of heart failure.To investigate whether exhaled acetone concentration changes after treatment in acute decompensated ...

journal_title：International heart journal

authors： Yokokawa T,Sato T,Suzuki S,Oikawa M,Yoshihisa A,Kobayashi A,Yamaki T,Kunii H,Nakazato K,Suzuki H,Saitoh SI,Ishida T,Shimouchi A,Takeishi Y

更新日期：2018-07-31 00:00:00

abstract：:The usefulness of coronary magnetic resonance angiography (cMRA) has been reported, although the difference in the diagnostic accuracy of different protocols has not been established.We compared conventional coronary angiography (CAG) and cMRA, conducted within 6 months in 24 consecutive patients between September 201...

journal_title：International heart journal

authors： Namba Y,Fuke S,Kashihara Y,Tanaka M,Yumoto A,Saito H,Sato T

更新日期：2016-09-28 00:00:00

abstract：:Friedreich's ataxia (FRDA), the most common subtype of early onset hereditary ataxia, is an autosomal recessive neurodegenerative disorder caused by unstable GAA expansions. Two-dimensional, pulse, and pulse tissue Doppler echocardiographic examinations were performed on 21 patients with GAA expansion. There was no as...

journal_title：International heart journal

authors： Koc F,Akpinar O,Yerdelen D,Demir M,Sarica Y,Kanadasi M

更新日期：2005-05-01 00:00:00

abstract：:A 65-year-old Japanese man complaining of general malaise and presenting with high fever was admitted to our hospital. He had untreated diabetes and hepatocellular carcinoma with liver cirrhosis. Overall findings of the patient indicated sepsis. Two blood cultures were positive for Streptococcus dysgalactiae, a group ...

journal_title：International heart journal

authors： Takahashi F,Wada Y,Hasebe N

更新日期：2019-01-25 00:00:00

abstract：:Activation of mineralocorticoid receptor (MR) is shown in resistant hypertension including diabetes mellitus. Although protein kinase C (PKC) signaling is involved in the pathogenesis of diabetic complications, an association between PKC and MR is not known. Activation of PKCα and PKCβ by TPA (12-O-Tetradecanoylphorbo...

journal_title：International heart journal

authors： Hayashi T,Shibata H,Kurihara I,Yokota K,Mitsuishi Y,Ohashi K,Murai-Takeda A,Jo R,Ohyama T,Sakamoto M,Tojo K,Tajima N,Utsunomiya K,Itoh H

更新日期：2017-10-21 00:00:00

abstract：:The aim of the present study was to determine whether symptoms of atrial fibrillation (AF) differ between patients with and without subsequent permanent AF. Sixty-four patients (68 +/- 10 years old, 45 males) were recruited. AF follow-up was started at the age of 61 +/- 10 years and accomplished in a median period of ...

journal_title：International heart journal

authors： Kawara T,Narumi J,Hirao K,Kasuya K,Kawabata M,Tojo N,Isobe M,Matsuura M

更新日期：2010-07-01 00:00:00

abstract：:Prostaglandin F(2alpha) (PGF(2alpha)) stimulates hypertrophic growth of neonatal rat cardiac myocytes, a feature of which includes downregulation of the Ca(2+)-ATPase (SERCA2), a major Ca(2+) transport protein in SR. The molecular mechanisms by which PGF(2alpha) inhibits SERCA2 gene expression remain unknown. We deter...

journal_title：International heart journal

authors： Hara S,Arai M,Tomaru K,Doi H,Koitabashi N,Iso T,Watanabe A,Tanaka T,Maeno T,Suga T,Yokoyama T,Kurabayashi M

更新日期：2008-05-01 00:00:00

abstract：:Prevalent atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM) represents an important issue with regard to stroke events caused by embolization and is associated with high mortality. Increased epicardial adipose tissue (EAT), which shows high metabolic activity, can locally influence the activi...

journal_title：International heart journal

authors： Muhib S,Fujino T,Sato N,Hasebe N

更新日期：2013-01-01 00:00:00

abstract：:The 5-hydroxytryptamine2A receptor antagonist sarpogrelate hydrochloride exerts its effect not only by inhibition of platelet aggregation, but also by some pleiotropic effects. We have reported that a low serum lipoprotein lipase (LPL) mass level reflects insulin resistance and may be a risk factor for atherosclerotic...

journal_title：International heart journal

authors： Nagayama D,Ohira M,Saiki A,Shirai K,Tatsuno I

更新日期：2014-01-01 00:00:00

abstract：:We experienced a 33-year-old patient with D-looped transposition of the great arteries (D-TGA) and a history of Senning operation who was referred to our institute with cardiogenic shock and subsequently underwent urgent paracorporeal ventricular assist device (VAD) implantation, which was a first in Japan, that was e...

journal_title：International heart journal

authors： Nakamura M,Imamura T,Kuwahara H,Nakagaito M,Yokoyama S,Doi T,Fukahara K,Yoshimura N,Kinugawa K

更新日期：2020-05-30 00:00:00

abstract：:Heart failure (HF) is a disease with high morbidity and mortality. In patients with HF, decreased cardiac output and blood redistribution results in decreased intestinal perfusion and destruction of intestinal barrier. Microorganisms and endotoxins can migrate into the blood circulation, aggravating systemic inflammat...

journal_title：International heart journal

authors： Jin B,Ji F,Zuo A,Liu H,Qi L,He Y,Wang Q,Zhao P

更新日期：2020-03-28 00:00:00

abstract：:Catheter ablation has been established to be an effective therapy for drug-refractory paroxysmal AF and is recommended as the treatment of choice for many patients, including those with a permanent pacemaker (PM). However, the clinical efficacy of catheter ablation of paroxysmal AF in patients with a permanent PM for ...

journal_title：International heart journal

authors： Wu JT,Dong JZ,Wang SL,Chu YJ,Wang LX,Yang CK

更新日期：2014-01-01 00:00:00

abstract：:Tenascin-C (TNC) is involved in aortic disease pathophysiology. This study aims to evaluate TNC's value for predicting in-hospital death in acute aortic dissection (AD).We prospectively enrolled consecutive patients with suspected acute AD within 48 hours from symptom onset. Serum TNC and C-reactive protein (CRP) leve...

journal_title：International heart journal

authors： Guo T,Zhou X,Zhu A,Peng W,Zhong Y,Chai X

更新日期：2019-07-27 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling leading to right ventricular hypertrophy (RVH) and failure. Peroxisome proliferator-activated receptor γ (PPARγ), a member of nuclear receptors, has been proved to ameliorate PAH. However, its effect on PAH-induced right ventricula...

journal_title：International heart journal

authors： Xu Y,Gu Q,Liu N,Yan Y,Yang X,Hao Y,Qu C

更新日期：2017-12-12 00:00:00

abstract：:Hyperglycemia is an established risk factor of coronary artery disease (CAD). However, hyperglycemia with preserved pancreatic β cell function induces hyperinsulinemia to correct the glucose profile and may even result in reactive hypoglycemia (RH), which induces an inflammatory response. In this study, the incidence ...

journal_title：International heart journal

authors： Murata M,Adachi H,Oshima S,Kurabayashi M

更新日期：2018-07-31 00:00:00

abstract：:The aim of this study was to investigate whether electrical stimulation of skeletal muscles could represent a rehabilitation alternative for patients with chronic heart failure (CHF). Thirty patients with CHF and NYHA class II-III were randomly assigned to a rehabilitation program using either electrical stimulation o...

journal_title：International heart journal

authors： Dobsák P,Nováková M,Fiser B,Siegelová J,Balcárková P,Spinarová L,Vítovec J,Minami N,Nagasaka M,Kohzuki M,Yambe T,Imachi K,Nitta S,Eicher JC,Wolf JE

更新日期：2006-05-01 00:00:00

abstract：:Coronary collateral circulation (CCC) plays a crucial role in myocardial blood supply, especially for ischemic myocardium. Previous study has shown that neuregulin-1 is a prominent angiogenic factor in diabetic cardiomyopathy, whereas the relationship between neuregulin-1 and CCC has not been investigated. Thus, we ai...

journal_title：International heart journal

authors： Huang M,Zheng J,Chen Z,You C,Huang Q

更新日期：2020-01-31 00:00:00

abstract：:We are pleased to announce that the following 4 articles have been selected for the the UEDA Heart Awards for the Year 2016.First PlaceDelivery of Imatinib-Incorporated Nanoparticles into Lungs Suppresses the Development of Monocrotaline-Induced Pulmonary Arterial HypertensionSatoshi Akagi, Kazufumi Nakamura, Daiji Mi...

journal_title：International heart journal

authors：

更新日期：2016-01-01 00:00:00

abstract：:Most previous studies have examined the effects of antihypertensive drugs in hypertensive animals for only a few months, and little information has been provided as to the protective effects of lifetime antihypertensive medication against cardiovascular organ injury. In this study, spontaneously hypertensive rats (SHR...

journal_title：International heart journal

authors： Ishimitsu T,Honda T,Ohno E,Furukata S,Sudo Y,Nakano N,Takahashi T,Ono H,Matsuoka H

更新日期：2010-01-01 00:00:00

abstract：:We report a case of atrioventricular nodal reentrant tachycardia coexistent with atresia of the coronary sinus ostium. Radiofrequency current application between the supposed coronary sinus ostium and the tricuspid valve was effective at eliminating the tachycardia. A coronary venogram obtained by left coronary arteri...

journal_title：International heart journal

authors： Okuyama Y,Oka T,Mizuno H,Sakai T,Hirayama A,Kodama K

更新日期：2005-09-01 00:00:00