Abstract：
OBJECTIVE:To determine insulin resistance in non-diabetic chronic hepatitis C patients using Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). METHODOLOGY:Patients having anti-HCV positive were included in this study. Patients with diabetes mellitus, thyroid disease, hyperlipidemias, hypercortisolism and infective diseases other than hepatitis C were excluded. Age, weight, height and absence of diabetes were documented. Fasting blood glucose and fasting insulin levels were done. Body mass index and insulin resistance was calculated using the formulas. Patients having insulin resistance using formula HOMA-IR>2.5 were labeled as insulin resistant. Data was analyzed using SPSS-18. RESULTS:One hundred and fifty five patients according to sample size estimation were enrolled, in whom HOMA-IR was calculated, the mean value was found to be 2.47 ±1.30. A total of 79 (51%) of patients had HOMA-IR more than 2.5 showing insulin resistance. CONCLUSION:In a third world country like Pakistan, where there is a high prevalence of hepatitis C infection, the consequences of the disease are also very common. Insulin resistance was found in 51% of patients with chronic hepatitis C.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Kiran Z,Zuberi BF,Anis D,Qadeer R,Hassan K,Afsar Sdoi
10.12669/pjms.291.2888subject
Has Abstractpub_date
2013-01-01 00:00:00pages
201-4issue
1eissn
1682-024Xissn
1681-715Xjournal_volume
29pub_type
杂志文章abstract：OBJECTIVE:To determine the role of serum procalcitonin (PCT) and C-reactive protein (CRP) in predicting spontaneous bacterial peritonitis (SBP) in patients with advanced liver cirrhosis. METHODS:A total of 88 patients with advanced liver cirrhosis were enrolled for this study, which included 40 cases with SBP and 48 c...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.326.10995
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:To determine site specific carotid intima-media thickness: common-carotid artery and carotid bifurcation in hypercholesterolemia patients as a marker for atherosclerosis. METHODS:Fifty patients with hypercholesterolemia and twenty controls were selected after getting informed consent regarding the investigat...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.295.3830
更新日期：2013-09-01 00:00:00
abstract：Objective:To compare the effectiveness of learning procedural skills on patients versus mannequins and models. Methods:Seventy four interns from two consecutive batches at the Department of Obstetrics and Gynaecolgy Unit-I at Jinnah Postgraduate Medical Center Karachi participated in the study between April and Septem...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.344.15521
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the detection rate accuracy of Double-balloon Enteroscopy (DBE) after Capsule Endoscopy (CE) in patients with suspected small bowel diseases. METHODOLOGY:From January 2009 to March 2012, sixty-two patients with obscure small bowel diseases who underwent CE followed by DB...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.292.2927
更新日期：2013-04-01 00:00:00
abstract：Objectives:To assess the immediate effect of TEAM® on trauma related knowledge of undergraduate medical students and to highlight the stakeholders' acceptability of TEAM® for trauma training of undergraduate medical students. Methods:Effectiveness of TEAM® course in terms of knowledge gain was assessed using 20-item-M...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.6.2588
更新日期：2020-09-01 00:00:00
abstract：Objective:To determine the efficacy of oral eplerenone in anatomical and functional improvement in patients with chronic central serous chorioretinopathy (CSCR). Methods:This quasi experimental study was performed at PNS Shifa Hospital Karachi from September 2018 to February 2019. Study included 23 patients. Patients ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.6.896
更新日期：2019-11-01 00:00:00
abstract：Objective:To investigate the relationship between myocardial enzymes, liver function and metabolic acidosis in children with rotavirus infection diarrhea. Methods:The data of 70 children with infectious diarrhea treated in Baoding Children's Hospital, China, from October 2017 to April 2018 were retrospectively studied...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.6.2325
更新日期：2020-09-01 00:00:00
abstract：Objective:To evaluate the therapeutic effects of pulpotomy and pulpectomy on deciduous molars with deep caries. Methods:A total of 124 children (192 molars) with deep caries treated from February 2014 to February 2015 were selected. They each had at least one molar with deep caries. MTA pulpotomy (101 molars) and Vita...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.336.13488
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of colporrhaphy on sexual problems of women with pelvic organ prolapseis. METHODOLOGY:Sixty patients with pelvic organ prolapse (cystocele - rectocele) in a quasi-experimental study before and after treatment were included. Presence of pelvic organ prolapseis was assessed by examinatio...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.291.2610
更新日期：2013-01-01 00:00:00
abstract：Objective:To compare the short-term outcomes of three dimensional (3D) versus two dimensional (2D) laparoscopic procedures used for cholecystectomy. Methods:This study was conducted at minimally invasive surgery center of Liaquat University of Medical Health and Sciences (LUMHS) Jamshoro Pakistan, between 15th May 201...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.37.1.3721
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:This study aims to determine expression of Glial Fibrillary Acidic Protein and of Alpha Smooth Muscle Actin (α-SMA) in hepatic stellate cells of CHC cases and their association with stage of fibrosis. METHODS:The study was conducted at Ziauddin University, Clifton Campus during the year 2010-2012. Sixty Chro...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.305.5534
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To determine correlation of serum total testosterone with body mass index (BMI) and waist hip ratio (WHR) in healthy adult males. METHODS:A cross sectional study was conducted on 200 nonsmoker healthy males (aged 30-50 years) university employees. They were selected by convenience sampling technique after a ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.312.6130
更新日期：2015-03-01 00:00:00
abstract：Background & Objective:Kidney Injury Molecule-1 (KIM-1) is a peptide whose release into circulation is specific to tubular injury. This study aimed to estimate levels of kidney injury molecule-1 in diabetic patients with and without kidney disease. And evaluate the role of KIM-1 as an early screening marker of progress...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.4.154
更新日期：2019-07-01 00:00:00
abstract：Objective:To correlate between hydronephrosis grades and detection of urinary stones by B-mode ultrasound imaging. Methods:This study included 210 ultrasound reports of patients who underwent abdominal ultrasound imaging in the period from 1st January 2016 to 31st October 2017, and diagnosed as hydronephrosis. Data co...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.344.14602
更新日期：2018-07-01 00:00:00
abstract：Background & Objective:The "silent thief" of bone osteoporosis is associated with various modifiable factors, identifying these factors is important in decreasing the prevalence of this highly prevalent disease. Therefore, this study was planned to identify these risk factors for osteoporosis in premenopausal and postm...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.3.551
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To assess inpatient management of non-critically ill type 2 diabetics with different insulin regimen. METHODS:We reviewed the medical records of all non-critically ill type 2 diabetic patients more than 18 years of age in medical department of civil hospital Karachi and Dow University of Health Sciences from...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
abstract：Objective:To explore the value of gastrointestinal endoscopy in the early diagnosis and treatment of gastrointestinal tumors and lay a foundation for the diagnosis and treatment of gastrointestinal tumors. Methods:One hundred and eight patients with gastrointestinal tumors who were admitted to our hospital from August...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.2.707
更新日期：2020-01-01 00:00:00
abstract：Objective:To study Agreement between Keratometric readings by VERION image guided System, Galilei G4 and Pentacam. Methods:The quasi experimental study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan from August 2016 to December 2016. Twenty five patients fulfilling the inclusion criteri...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.343.14577
更新日期：2018-05-01 00:00:00
abstract：Objective:To evaluate the concentration of N terminal proBNP (NT-proBNP) and partially the serum uric acid in the severe condition of aortic valve dysfunction for assessment of left ventricle hypertrophy. Methods:The study was conducted in the signal transduction lab department of biochemistry Quaid-I-Azam University,...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.1.148
更新日期：2019-01-01 00:00:00
abstract：Objective:The study examines the level and source of perceived social support in pregnant adolescents and the factors related to their perception of social support. Methods:This descriptive study was conducted with the voluntary participation of 127 adolescent pregnant females who visited the Gynecology and Pediatric ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.341.14221
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:Immunosuppressive drugs, antimicrobial agents and infectious complications may cause liver function test abnormalities (LFTA) in kidney transplant recipients (KTR). The objectives of this study were to identify the outcome of (LFTA). To identify the risk factors affecting development and severity of hepatotox...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.326.10725
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVES:To compare the scorings of real and standardized patients on physician communication skills. METHODS:Patient scoring (n=183) on physicians' communication skills was determined by 93 real and 90 standardized patients. Eighty physicians (42 specialists and 38 general physicians) in private practice were enrol...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.303.3255
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:To analyse the factors associated with Caesarean Section (CS) of Nulliparous, Term and Singleton pregnancies with Vertex presentation (NTSV) at a tertiary care hospital. METHODS:In this unmatched retrospective case-control study, 212 NTSV patients were identified through computerized medical record systems; ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.322.9138
更新日期：2016-03-01 00:00:00
abstract：:Miller Fisher's syndrome (MFS) commonly presents in the fourth and fifth decades and are rare in people over 70 years. An 85-year-old female with no significant medical history presented with upper extremity anesthesia, ptosis, and unsteady gait. The patient had a history of hypertension and diabetes mellitus. Physica...
journal_title：Pakistan journal of medical sciences
pub_type：
doi：10.12669/pjms.295.3793
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To explore the correlation between magnetic resonance imaging (MRI) features of uterine fibroids (UFs) and therapeutic effects of high-intensity focused ultrasound ablation (HIFUA), and to provide evidence for UFs diagnosis with MRI in clinical practice. METHODS:Forty-three UFs patients who were treated in o...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.314.7294
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:To study the association between Protein energy malnutrition and polio-specific immunoglobulin G antibodies production among children in Gadap Town Karachi, Pakistan. METHODS:Comparative cross sectional survey conducted at fixed EPI center and Pediatric OPD of a tertiary care hospital Karachi. Children were ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.312.5366
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To compare the effects of thoracotomy and total thoracoscopic surgery on coronary artery fistulae complicated with ectasia. METHODS:Forty-six patients with coronary artery fistulae complicated with ectasia were randomly divided into a treatment group and a control group (n=23) which were given totally thorac...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.321.7501
更新日期：2016-01-01 00:00:00
abstract：Objectives:To measure correlation and concordance between measured LDL cholesterol (mLDLc) and Friedewald's calculated LDL cholesterol (cLDLc). To compare the mLDLc and cLDLc values for various anthropometric measures and biochemical indices including insulin resistance, nephropathy, glycated hemoglobin and triglycerid...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.35.2.679
更新日期：2019-03-01 00:00:00
abstract：:COVID-19 is a viral infection that has multisystemic physical and psychological complications. The following paper looks at the various challenges seen while treating psychiatric patients during the COVID pandemic. There is a need for physician to be aware of the drug interactions between psychiatric medications and t...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.36.5.3073
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To explore the effects of letrozole (LE) in combination with low-dose intramuscular injection of human menopausal gonadotropin (HMG) on the ovulation induction and pregnancy of patients with polycystic ovary syndrome (PCOS). METHODS:A total of 156 patients with PCOS infertility were randomly divided into an ...
journal_title：Pakistan journal of medical sciences
pub_type： 杂志文章
doi：10.12669/pjms.326.11391
更新日期：2016-11-01 00:00:00
