Abstract:
Objective:To determine the efficacy of oral eplerenone in anatomical and functional improvement in patients with chronic central serous chorioretinopathy (CSCR). Methods:This quasi experimental study was performed at PNS Shifa Hospital Karachi from September 2018 to February 2019. Study included 23 patients. Patients were included using consecutive sampling technique and informed consent was taken from all patients before staring treatment. 50 mg of oral eplerenone per day was given for three months. Subretinal fluid (SRF) height and visual acuity (VA) were noted at baseline, one month and three month follow-up. Structured Study performa was used for data collection. Data was analysed and assessed with SPSS version 23. P value of <0.05 was considered statistically significant. Results:Mean age of patients was 40.7±7 years and mean duration of disease before treatment was 3.7±0.76 months. Mean baseline BCVA and SRF height was 0.39±0.02 logMAR and 123±12.5 µm respectively. Sixty-five percent patients responded at one month and 80% at three months with reduction in SRF height. Improvement in visual acuity was also statistically significant at 3 months (p<0.05). Conclusion:Use of eplerenone in chronic CSCR resulted in significant improvement in vision and decrease in mean SRF height.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Farooq O,Habib A,Shah MA,Ahmed Ndoi
10.12669/pjms.35.6.896subject
Has Abstractpub_date
2019-11-01 00:00:00pages
1544-1547issue
6eissn
1682-024Xissn
1681-715Xpii
PJMS-35-1544journal_volume
35pub_type
杂志文章abstract:OBJECTIVE:To assess the Knowledge, Attitude and Practices (KAP) towards diabetes and diabetic retinopathy in the general population of Bin Qasim Town (BQ), Karachi. METHODS:An observational, cross-sectional study was approved by Research Ethical Committee of Al-Ibrahim Eye Hospital. It included every third household b...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.311.6317
更新日期:2015-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
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更新日期:2019-11-01 00:00:00
abstract:Objective:To evaluate the feasibility and safety of marking targeting biopsy (MTB) in the intraoperative localization value of colon polypectomy. Methods:The clinical data from patients with polyp of colon discovered under colonoscopy from January 2014 to January 2016 were retrospectively analyzed. A total of 87 patie...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.2.756
更新日期:2020-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2017-05-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.4.368
更新日期:2019-07-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2019-09-01 00:00:00
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journal_title:Pakistan journal of medical sciences
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更新日期:2021-01-01 00:00:00
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更新日期:2019-09-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
abstract:Objective:The study examines the level and source of perceived social support in pregnant adolescents and the factors related to their perception of social support. Methods:This descriptive study was conducted with the voluntary participation of 127 adolescent pregnant females who visited the Gynecology and Pediatric ...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2018-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.303.3255
更新日期:2014-05-01 00:00:00
abstract:Objectives:The value of gastric residual volume (GRV) monitoring in ventilator-associated pneumonia (VAP) has frequently been questioned in the past years. In this trial, the effect of GRV on the frequency of VAP was evaluated in critically ill patients under mechanical ventilation. Methods:This descriptive study was ...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.2.1321
更新日期:2020-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.303.4798
更新日期:2014-05-01 00:00:00
abstract:Objective:To determine the frequency of Allergic Fungal Rhino-sinusitis (AFRS) in Chronic Rhino-sinusitis (CRS) patients and the accuracy of fungal culture in diagnosing AFRS. Methods:Immunocompetent patients with CRS and without invasive fungal rhino-sinusitis presenting over a period of 3 years in ENT department of ...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.3.1661
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND & OBJECTIVE:Rehabilitation focuses brain-behavior relationship which highlights interaction between psychological and neurobiological factors for better patient care. There is a missing link in the literature about socio-cognitive aspects of frontal lobe epilepsy. Our objective was to examine prefrontal cort...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.331.11742
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Genetic studies on gestational diabetes (GDM) are relatively scarce; moreover, limited data is available for KCNQ1 polymorphism in Pakistani pregnant women. We aimed to determine the frequency of KCNQ1 rs2237895 in GDM and normal pregnant controls and its association with GDM-related phenotypes...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.326.11052
更新日期:2016-11-01 00:00:00
abstract:Objectives:There is lack of evidence exploring sympathetic effect by baroreceptor sensitivity in obese consuming energy drink. The purpose of this study was to investigate the acute effect of energy drink on individuals baroreceptor sensitivity in young healthy normal weight and overweight/obese males. Methods:This cr...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.7.2419
更新日期:2020-11-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.2.243
更新日期:2019-03-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.324.9384
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:To investigate the reperfusion time in patients with ST-segment elevation myocardial infarction (STEMI) in Henan Province, China, and discuss the strategies for shortening that period. METHODS:The reperfusion times of 1556 STEMI cases in 30 hospitals in Henan Province were analyzed from January 2008 to Augus...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.306.5696
更新日期:2014-11-01 00:00:00
abstract:Objectives:To determine the hematological indices and ratios derived from them in patients with fibromyalgia and to correlate the scores of Fibromyalgia Impact Questionnaire Revised (FIQR) with the ratios. Methods:This case control study was performed in the College of Pharmacy at Hawler Medical University in Erbil-Ir...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.345.15169
更新日期:2018-09-01 00:00:00
abstract::The WHO has declared a Pandemic due to Novel Corona virus-19 (COVID-19). Patients usually have respiratory symptoms but gastrointestinal and hepatic dysfunction are not uncommon presentations and can lead to a delay in diagnosis and management. Virus shedding can continue even after the nasopharyngeal swab gets negati...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.COVID19-S4.2651
更新日期:2020-05-01 00:00:00
abstract:Objective:Extensive drug resistant Gram-negative bacilli, harboring New Delhi metallo-β-lactamase-1 (blaNDM-1) having the ability to hydrolyze β-lactams, have become a vital global clinical threat. The present study was, therefore, designed to investigate the prevalence and epidemiology of NDM-1 producers in Quetta, Pa...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.4.372
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:Ventilator-associated pneumonia (VAP) is a significant cause of hospital-related infections, one that must be prevented due to its high morbidity and mortality. The purpose of this study was to evaluate the incidence and risk factors in patients developing VAP in our intensive care units (ICUs). METHODS:Thi...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.324.10381
更新日期:2016-07-01 00:00:00
abstract::Synergistic associations between infection and nutrition are well known. Impact of nutrition interventions on the outcomes have been scientifically assessed and reported. The role of nutrition in limiting the infection related morbidity and mortality does not appear to be a debatable question but nutrition interventio...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章,评审
doi:10.12669/pjms.36.COVID19-S4.2784
更新日期:2020-05-01 00:00:00