MicroRNA-325 alleviates myocardial fibrosis after myocardial infarction via downregulating GLI1.

abstract：OBJECTIVE:To explore the expression and function of insulin-like growth factor II (IGFII) mRNA binding protein (IMP3) in the Triple Negative Breast Cancer (TNBC). MATERIALS AND METHODS:According to previously reported gene expression array, we found that IMP3 had significantly higher expression in the CD44+CD24-ESA+ c...

journal_title：European review for medical and pharmacological sciences

authors： Huang QD,Zheng SR,Cai YJ,Chen DL,Shen YY,Lin CQ,Hu XQ,Wang XH,Shi H,Guo GL

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of highly-expressed FOSL1 on the tumorigenesis and metastasis of prostate cancer. PATIENTS AND METHODS:Researches were carried out in human prostate cancer tissues and cell lines. In prostate cancer tissues, the expression of FOSL was detected by immunohistochemistry. In vitro cell ...

journal_title：European review for medical and pharmacological sciences

authors： Luo YZ,He P,Qiu MX

更新日期：2018-12-01 00:00:00

abstract：:Fluoxetine drops and marketed fluoxetine capsules had quite the same Cmax (50.25 +/- 4.43 vs 47.55 +/- 5.29 ng/ml), but significantly different AUC0-t (717.27 +/- 71.29 vs 644.91 +/- 78.91 ng/ml/h). Furthermore the drops were characterised by a very early Tmax (4.61 +/- 0.85 hours) with a highly significant difference...

journal_title：European review for medical and pharmacological sciences

authors： Floriddia ML,Castorina M,Drago F

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:The occurrence rate of delayed fracture healing in diabetes mellitus patients is high. Transforming growth factor β1 (TGF-β1) is an important regulatory factor in bone tissue repair and regeneration. However, TGF-β1 expression and its function in diabetic patient fracture have not been fully elucidated. PATI...

journal_title：European review for medical and pharmacological sciences

authors： Wang WD,Cheng BZ,Kang WB,Zheng RW,Cai YL,Wang XJ

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To identify laboratory markers among platelet indices, coagulation parameters, blood lipid parameters, and liver/kidney function variables that can be used to predict preeclampsia. PATIENTS AND METHODS:We studied records of 568 women with preeclampsia, gestational hypertension (GH), or normal term pregnancie...

journal_title：European review for medical and pharmacological sciences

authors： Han Q,Zheng W,Guo XD,Zhang D,Liu HF,Yu L,Yan JY

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Hepatocarcinoma is a great threat to global health. MicroRNA-23a was suggested to regulate growth and apoptosis in certain cell lines. Our study was focused on growth, proliferation, and apoptosis of hepatocarcinoma cell line MHCC97H under the influence of microRNA-23a, and explored the mechanism of pro-apopt...

journal_title：European review for medical and pharmacological sciences

authors： Ji DG,Jiang CW,Luo X,Liu Z,Huang WJ,Zhang XH,Yu TH,Zhang LR

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To investigate the association between bone morphogenetic protein 4 (BMP4) expression and clinical pathology, computed tomography (CT) characteristics and prognosis of patients with non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:A total of 76 NSCLC patients treated in our hospital from July 2012 to...

journal_title：European review for medical and pharmacological sciences

authors： Ju FJ,Meng FQ,Hu HL,Liu J

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Aortic valve stenosis (AS) presents a disease during which there are changes of the aortic valve structure that modify the blood structure of patients. The aim of this study was to improve the effectiveness of differential diagnostics of aortic stenosis and aortic regurgitation using molecular techniques on b...

journal_title：European review for medical and pharmacological sciences

authors： Urban P,Rabajdová M,Špaková I,Sabol F,Mičková H,Lakatosová K,Zavacká M

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to explore the role of HOTAIR in inflammatory response after acute myocardium infarction (AMI) and to investigate its underlying mechanism. MATERIALS AND METHODS:The AMI model was first constructed in rats, and heart tissues were harvested. Expression levels of HOTAIR and receptor o...

journal_title：European review for medical and pharmacological sciences

authors： Lu W,Zhu L,Ruan ZB,Wang MX,Ren Y,Li W

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Functional pelvic disorders in patients undergoing conservative surgical approach for rectal cancer are considered a major public health issue and represent one third of cost of colorectal cancer. We investigated the hypothesis that lymphadenectomy, involves the pelvic floor results in a localized hides or s...

journal_title：European review for medical and pharmacological sciences

authors： Vannelli A,Basilico V,Zanardo M,Caizzone A,Rossi F,Battaglia L,Scaramuzza D

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:This paper aims to investigate the interaction mechanism between pioglitazone/simvastatin and the CD40-CD40 ligand (CD40-CD40L) system and to determine their interaction effects on atherosclerosis in rabbits. MATERIALS AND METHODS:Forty rabbits were randomly divided into five groups of eight: normal control,...

journal_title：European review for medical and pharmacological sciences

authors： Xue L,Zhu XH,Yang XF,Bao XC,Gao XQ,Qiu YH,Wu Z,Ji XP,Li HW

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Dysregulation of numerous oncogenes and their downstream signaling pathways, among others in the signaling transduction molecule p-CREB-1 (p-cAMP responsive element binding protein-1), is an essential feature of different types of cancer. To investigate whether p-CREB-1 is also pivotal in tumorigenesis and me...

journal_title：European review for medical and pharmacological sciences

authors： Xin ZC,Hu HW,Lao ZH,Zhu LQ,Biskup E,Zhang HW

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Fatty liver may induce various complications including chronic hepatitis or liver cirrhosis, and is frequently occurred in obesity individuals. Advanced glycosylation end products (AGEs) were known to play a critical role in multiple liver diseases. This study, therefore, aimed to study the effect of AGEs on ...

journal_title：European review for medical and pharmacological sciences

authors： Xiong DD,Zhang M,Li N,Gai JF,Mao L,Li M

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia (AML), as standing out for its distinguished sensitivity to all-trans retinoic acid and arsenic trioxide (ATO, As2O3). The As2O3-mediated degradation of PML-RARA (promyelocytic leukemia-retinoic acid receptor-α) oncoprotein via...

journal_title：European review for medical and pharmacological sciences

authors： Liu DM,Zhang XD,Yang L

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Lung adenocarcinoma (LAC) is the most common type of lung cancer, accounting for 30-35% of all cases. AIM:In this study we aim to predict potential genes and confirm pathways which are associated with LAC. MATERIALS AND METHODS:By using the meta-analysis method, GSE10072 and GSE 2514 datasets were merged t...

journal_title：European review for medical and pharmacological sciences

authors： Lin ZF,Shen XY,Lu FZ,Ruan Z,Huang HL,Zhen J

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:With the modifications that we made, the aim is to increase the effectiveness and the success rate of the Raz operation in the treatment of stress urinary incontinence (SUI) and to present a new approach in the treatment by reducing the complication rates. PATIENTS AND METHODS:Between November 2002 and Dece...

journal_title：European review for medical and pharmacological sciences

authors： Pirinççi N,Kamberoglu H,Kaya C,Kaba M,Geçit I,Guneş M,Ceylan K,Karaman MI

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Atherosclerosis is featured as artery wall thickness as a result of invasion and accumulation of white blood cells and proliferation of intimal smooth muscle cells. Endothelial dysfunction has been linked to a variety of vascular diseases, including atherosclerosis. MicroRNAs play essential roles during the a...

journal_title：European review for medical and pharmacological sciences

authors： Liu G,Li Y,Gao XG

更新日期：2016-07-01 00:00:00

abstract：AIM:Gastrointestinal tract duplications (GTD) are rare congenital abnormalities that can occur anywhere along the gastrointestinal tract. These anomalies may present as a single, multiple, or a vague pathologies. Diagnosing and treating these diseases may be difficult in some patients. We aimed to present 32 patients w...

journal_title：European review for medical and pharmacological sciences

authors： Okur MH,Arslan MS,Arslan S,Aydogdu B,Türkçü G,Goya C,Uygun I,Cigdem MK,Önen A,Otcu S

更新日期：2014-01-01 00:00:00

abstract：:This review illustrates some brief considerations of the medical use of cannabis recently issued in Italy. History and uses of cannabis throughout centuries and different countries are illustrated together with a description of botany and active phytocannabinoids. Then, medical use of cannabis anti-pain treatment for ...

journal_title：European review for medical and pharmacological sciences

authors： Zaami S,Di Luca A,Di Luca NM,Montanari Vergallo G

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Pulmonary embolism (PE) is a primary clinical manifestation of venous thromboembolism (VTE). It has been demonstrated that pulmonary endothelial cells (PECs) are apoptotic-resistant in PE. MATERIALS AND METHODS:In this study, PECs were collected from PE patients and mouse models. Western blot, RT-PCR, flow c...

journal_title：European review for medical and pharmacological sciences

authors： Mao HY,Liu LN,Hu YM

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To explore the relationship between IgH gene rearrangement and orbital MALT (mucose-associated lymphoid tissue) lymphoma removal operation prognosis, and to quantify the effect of IgH gene rearrangement on primary orbital MALT lymphoma prognosis. PATIENTS AND METHODS:Fifty-eight patient cases with primary or...

journal_title：European review for medical and pharmacological sciences

authors： Ding B,Ju ZC,Liu JM

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the effect of microRNA-214-5p (miR-214-5p) on spinal cord injury (SCI) and to explore the mechanism of action in pathophysiological relevance. MATERIALS AND METHODS:The model of SCI was successfully established in rats aged 6-8 weeks. The levels of the locomotor funct...

journal_title：European review for medical and pharmacological sciences

authors： A JC,Li ZY,Long QF,Wang DY,Zhao HS,Jia SL,Zhang WH

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of autophagy on acute myocardial infarction (AMI), and its mechanism in rats. MATERIALS AND METHODS:A total of 75 Sprague Dawley (SD) rats were randomly divided into three groups (n=25): sham operation (S) group, the AMI group and rapamycin (RAPA) treatment group. The model of AMI w...

journal_title：European review for medical and pharmacological sciences

authors： Aisa Z,Liao GC,Shen XL,Chen J,Li L,Jiang SB

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of recombinant activated coagulation factor VII (rFVIIa) on apoptosis and the expressions of B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax) in rats with intracerebral hemorrhage (ICH). MATERIALS AND METHODS:A total of 90 8-week-old male Sprague-Dawley (SD) rats with...

journal_title：European review for medical and pharmacological sciences

authors： Ma YM,Zheng JX,Xu X,Shan YS,Gao ZW,Chen WG

更新日期：2018-08-01 00:00:00

abstract：:Paracetamol, also known as acetaminophen, is the most commonly used antipyretic and pain reliever and since 1955 it is available over-the-counter as a single formulation or in combination with other substances and, as indicated by the World Health Organization, it can be used in all the three steps of pain intensity. ...

journal_title：European review for medical and pharmacological sciences

authors： Tittarelli R,Pellegrini M,Scarpellini MG,Marinelli E,Bruti V,di Luca NM,Busardò FP,Zaami S

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the inhibitory role of microRNA-1299 (miR-1299) in prostate cancer, and to explore the possible underlying mechanism. PATIENTS AND METHODS:The expression of miR-1299 in 35 PCa tissues and para-carcinoma tissues, as well as PCa cell lines (PC-3) and prostatic epithelia...

journal_title：European review for medical and pharmacological sciences

authors： Zhang FB,Du Y,Tian Y,Ji ZG,Yang PQ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It is increasingly recognized that a low grade of systemic inflammation occurs in patients with advanced chronic obstructive pulmonary disease (COPD). C-reactive protein (CRP), a marker of systemic chronic inflammatory response, has been related with decreased survival in large cohorts of COPD...

journal_title：European review for medical and pharmacological sciences

authors： Gatta D,Aliprandi G,Pini L,Zanardini A,Fredi M,Tantucci C

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Aim of this study was to identify whether docosahexaenoic acid (DHA) has a vital antidepressant by hypothalamic-pituitary-adrenal axis (HPA axis) or not. METHODS:Mice were divided into 2 groups: control group and DHA dietary group. DHA dietary group was treated with DHA dietary everyday for consecutive 50 da...

journal_title：European review for medical and pharmacological sciences

authors： Jiang LH,Liang QY,Shi Y

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Several elimination diets have been suggested based on results of skin prick tests (SPTs) or IgE antibodies to foods, thus allowing the identification of the most common offending food(s), including CM (cow's milk), egg, peanut and wheat. But unbalanced, inappropriate dietary manipulation in infants with foo...

journal_title：European review for medical and pharmacological sciences

authors： Cantani A

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Alcoholic hepatitis (AH) is a type of alcoholic liver disorder caused by overconsumption of alcohol. The involvement of several transcription factors (TF), as the main regulators of disease related gene expression has been documented previously. However, despite the importance of analysis of gene regulatory n...

journal_title：European review for medical and pharmacological sciences

authors： Mohammadnia A,Yaqubi M,Fallahi H

更新日期：2015-06-01 00:00:00