Application of spherical diodes for megavoltage photon beams dosimetry.

Abstract:

PURPOSE:External beam radiation therapy (EBRT) usually uses heterogeneous dose distributions in a given volume. Designing detectors for quality control of these treatments is still a developing subject. The size of the detectors should be small to enhance spatial resolution and ensure low perturbation of the beam. A high uniformity in angular response is also a very important feature in a detector, because it has to measure radiation coming from all the directions of the space. It is also convenient that detectors are inexpensive and robust, especially to perform in vivo measurements. The purpose of this work is to introduce a new detector for measuring megavoltage photon beams and to assess its performance to measure relative dose in EBRT. METHODS:The detector studied in this work was designed as a spherical photodiode (1.8 mm in diameter). The change in response of the spherical diodes is measured regarding the angle of incidence, cumulated irradiation, and instantaneous dose rate (or dose per pulse). Additionally, total scatter factors for large and small fields (between 1 × 1 cm(2) and 20 × 20 cm(2)) are evaluated and compared with the results obtained from some commercially available ionization chambers and planar diodes. Additionally, the over-response to low energy scattered photons in large fields is investigated using a shielding layer. RESULTS:The spherical diode studied in this work produces a high signal (150 nC/Gy for photons of nominal energy of 15 MV and 160 for 6 MV, after 12 kGy) and its angular dependence is lower than that of planar diodes: less than 5% between maximum and minimum in all directions, and 2% around one of the axis. It also has a moderated variation with accumulated dose (about 1.5%/kGy for 15 MV photons and 0.7%/kGy for 6 MV, after 12 kGy) and a low variation with dose per pulse (± 0.4%), and its behavior is similar to commercial diodes in total scatter factor measurements. CONCLUSIONS:The measurements of relative dose using the spherical diode described in this work show its feasibility for the dosimetry of megavoltage photon beams. A particularly important feature is its good angular response in the MV range. They would be good candidates for in vivo dosimetry, and quality assurance of VMAT and tomotherapy, and other modalities with beams irradiating from multiple orientations, such as Cyberknife and ViewRay, with minor modifications.

journal_name

Med Phys

journal_title

Medical physics

authors

Barbés B,Azcona JD,Burguete J,Martí-Climent JM

doi

10.1118/1.4837178

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

012102

issue

1

eissn

0094-2405

issn

2473-4209

journal_volume

41

pub_type

杂志文章
  • Evaluation of delivered monitor unit accuracy of gated step-and-shoot IMRT using a two-dimensional detector array.

    abstract:PURPOSE:To overcome the problem of organ motion in intensity-modulated radiation therapy (IMRT), gated IMRT is often used for the treatment of lung cancer. In this study, the authors investigated the accuracy of the delivered monitor units (MUs) from each segment during gated IMRT using a two-dimensional detector array...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3310806

    authors: Cheong KH,Kang SK,Lee M,Kim SS,Park S,Hwang TJ,Kim KJ,Oh DH,Bae H,Suh TS

    更新日期:2010-03-01 00:00:00

  • A data-mining framework for large scale analysis of dose-outcome relationships in a database of irradiated head and neck cancer patients.

    abstract:PURPOSE:To develop a hypothesis-generating framework for automatic extraction of dose-outcome relationships from an in-house, analytic oncology database. METHODS:Dose-volume histograms (DVH) and clinical outcomes have been routinely stored to the authors' database for 684 head and neck cancer patients treated from 200...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4922686

    authors: Robertson SP,Quon H,Kiess AP,Moore JA,Yang W,Cheng Z,Afonso S,Allen M,Richardson M,Choflet A,Sharabi A,McNutt TR

    更新日期:2015-07-01 00:00:00

  • Quantitative study of focused ultrasound enhanced doxorubicin delivery to prostate tumor in vivo with MRI guidance.

    abstract:PURPOSE:The purpose of this study was to investigate the potential of MR-guided pulsed focused ultrasound (pFUS) for the enhancement of drug uptake in prostate tumors in vivo using doxorubicin (Dox). METHODS:An antitumor drug Dox, an orthotopic animal prostate tumor model using human prostate cancer, LNCaP cell line, ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4705346

    authors: Chen X,Cvetkovic D,Ma CM,Chen L

    更新日期:2012-05-01 00:00:00

  • Patient dose simulations for scanning-beam digital x-ray tomosynthesis of the lungs.

    abstract:PURPOSE:An improved method of image guidance for lung tumor biopsies could help reduce the high rate of false negatives. The aim of this work is to optimize the geometry of the scanning-beam digital tomography system (SBDX) for providing real-time 3D tomographic reconstructions for target verification. The unique geome...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4826159

    authors: Nelson G,Yoon S,Krishna G,Wilfley B,Fahrig R

    更新日期:2013-11-01 00:00:00

  • Optimizing cone beam CT scatter estimation in egs_cbct for a clinical and virtual chest phantom.

    abstract:PURPOSE:Cone beam computed tomography (CBCT) image quality suffers from contamination from scattered photons in the projection images. Monte Carlo simulations are a powerful tool to investigate the properties of scattered photons.egs_cbct, a recent EGSnrc user code, provides the ability of performing fast scatter calcu...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4881142

    authors: Thing RS,Mainegra-Hing E

    更新日期:2014-07-01 00:00:00

  • Validation of a method for in vivo 3D dose reconstruction for IMRT and VMAT treatments using on-treatment EPID images and a model-based forward-calculation algorithm.

    abstract:PURPOSE:Radiation treatments are trending toward delivering higher doses per fraction under stereotactic radiosurgery and hypofractionated treatment regimens. There is a need for accurate 3D in vivo patient dose verification using electronic portal imaging device (EPID) measurements. This work presents a model-based te...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4935199

    authors: Van Uytven E,Van Beek T,McCowan PM,Chytyk-Praznik K,Greer PB,McCurdy BM

    更新日期:2015-12-01 00:00:00

  • Direction modulated brachytherapy (DMBT) for treatment of cervical cancer: A planning study with 192 Ir, 60 Co, and 169 Yb HDR sources.

    abstract:PURPOSE:To evaluate plan quality of a novel MRI-compatible direction modulated brachytherapy (DMBT) tandem applicator using 192 Ir, 60 Co, and 169 Yb HDR brachytherapy sources, for various cervical cancer high-risk clinical target volumes (CTVHR ). MATERIALS AND METHODS:The novel DMBT tandem applicator has six periphe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12598

    authors: Safigholi H,Han DY,Mashouf S,Soliman A,Meigooni AS,Owrangi A,Song WY

    更新日期:2017-12-01 00:00:00

  • Technical note: A novel boundary condition using contact elements for finite element based deformable image registration.

    abstract::Deformable image registration is an important tool for image-guided radiotherapy. Physics-model-based deformable image registration using finite element analysis is one of the methods currently being investigated. The calculation accuracy of finite element analysis is dependent on given boundary conditions, which are ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1774131

    authors: Zhang T,Orton NP,Mackie TR,Paliwal BR

    更新日期:2004-09-01 00:00:00

  • Characterization of fragmented heavy-ion beams using a three-stage telescope detector: measurements of 670-MeV/amu 20Ne beams.

    abstract::Measurements of a 670-MeV/amu 20Ne beam at the Lawrence Berkeley Laboratory Bevalac heavy-ion accelerator with various thicknesses of water absorber were obtained with the BERKLET. The BERKLET, a simple three-stage solid-state telescope detector, has been described previously. This instrument measures the linear energ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596536

    authors: Llacer J,Schmidt JB,Tobias CA

    更新日期:1990-03-01 00:00:00

  • Definition of parameters for quality assurance of flattening filter free (FFF) photon beams in radiation therapy.

    abstract:PURPOSE:Flattening filter free (FFF) beams generated by medical linear accelerators have recently started to be used in radiotherapy clinical practice. Such beams present fundamental differences with respect to the standard filter flattened (FF) beams, making the generally used dosimetric parameters and definitions not...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4754799

    authors: Fogliata A,Garcia R,Knoos T,Nicolini G,Clivio A,Vanetti E,Khamphan C,Cozzi L

    更新日期:2012-10-01 00:00:00

  • Projection-domain scatter correction for cone beam computed tomography using a residual convolutional neural network.

    abstract:PURPOSE:Scatter is a major factor degrading the image quality of cone beam computed tomography (CBCT). Conventional scatter correction strategies require handcrafted analytical models with ad hoc assumptions, which often leads to less accurate scatter removal. This study aims to develop an effective scatter correction ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13583

    authors: Nomura Y,Xu Q,Shirato H,Shimizu S,Xing L

    更新日期:2019-07-01 00:00:00

  • A fast double template convolution isocenter evaluation algorithm with subpixel accuracy.

    abstract:PURPOSE:To design a fast Winston Lutz (fWL) algorithm for accurate analysis of radiation isocenter from images without edge detection or center of mass calculations. METHODS:An algorithm has been developed to implement the Winston Lutz test for mechanical/ radiation isocenter agreement using an electronic portal imagi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3524227

    authors: Winey B,Sharp G,Bussière M

    更新日期:2011-01-01 00:00:00

  • Material-specific analysis using coherent-scatter imaging.

    abstract::Coherent-scatter computed tomography (CSCT) is a novel imaging method we are developing to produce cross-sectional images based on the low-angle (<10 degrees) scatter properties of tissue. At diagnostic energies, this scatter is primarily coherent with properties dependent upon the molecular structure of the scatterer...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1493216

    authors: Batchelar DL,Cunningham IA

    更新日期:2002-08-01 00:00:00

  • Fast internal marker tracking algorithm for onboard MV and kV imaging systems.

    abstract::Intrafraction organ motion can limit the advantage of highly conformal dose techniques such as intensity modulated radiation therapy (IMRT) due to target position uncertainty. To ensure high accuracy in beam targeting, real-time knowledge of the target location is highly desired throughout the beam delivery process. T...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2905225

    authors: Mao W,Wiersma RD,Xing L

    更新日期:2008-05-01 00:00:00

  • Combined mixed approach algorithm for in-line phase-contrast x-ray imaging.

    abstract:PURPOSE:In the past decade, phase-contrast imaging (PCI) has been applied to study different kinds of tissues and human body parts, with an increased improvement of the image quality with respect to simple absorption radiography. A technique closely related to PCI is phase-retrieval imaging (PRI). Indeed, PCI is an ima...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3447727

    authors: De Caro L,Scattarella F,Giannini C,Tangaro S,Rigon L,Longo R,Bellotti R

    更新日期:2010-07-01 00:00:00

  • Dose distributions around cylindrical 241Am sources for a clinical intracavitary applicator.

    abstract::Encapsulated, cylindrical sources containing 2, 5, and 8 Ci of 241Am have been designed and fabricated for intracavitary irradiation of uterine cancers. Exposure rates in air and dose rates in water around these sources have been measured using an ionization chamber and a lithium fluoride thermoluminescent dosimetry s...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596007

    authors: Nath R,Gray L,Park CH

    更新日期:1987-09-01 00:00:00

  • Comparing calibration methods of electron beams using plane-parallel chambers with absorbed-dose to water based protocols.

    abstract::Recent absorbed-dose-based protocols allow for two methods of calibrating electron beams using plane-parallel chambers, one using the N(Co)D,w for a plane-parallel chamber, and the other relying on cross-calibration of the plane-parallel chamber in a high-energy electron beam against a cylindrical chamber which has an...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1449876

    authors: Stewart KJ,Seuntjens JP

    更新日期:2002-03-01 00:00:00

  • Technical note: An algorithm to calculate the tissue phantom ratio from depth dose in radiosurgery.

    abstract:PURPOSE:To propose a method to calculate the tissue phantom ratio (TPR) using the depth dose and to compare the proposed method with two other methods. METHODS:An analytical dose model from Bjärngard was used to describe the depth dose and the TPR. The parameters of the model were derived from depth dose measurements,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3570575

    authors: Ramos Garcia LI,Almansa JF

    更新日期:2011-05-01 00:00:00

  • Simplifying volumes-of-interest (VOIs) definition in quantitative SPECT: Beyond manual definition of 3D whole-organ VOIs.

    abstract:PURPOSE:We investigated the feasibility of using simpler methods than manual whole-organ volume-of-interest (VOI) definition to estimate the organ activity concentration in single photon emission computed tomography (SPECT) in cases where the activity in the organ can be assumed to be uniformly distributed on the scale...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12164

    authors: Vicente EM,Lodge MA,Rowe SP,Wahl RL,Frey EC

    更新日期:2017-05-01 00:00:00

  • Application of the convolution method for calculation of output factors for therapy photon beams.

    abstract::The output factor for a therapy photon beam is defined as the dose per monitor unit relative to the dose per monitor unit in a reference field. Convolution models for photon dose calculations yield the dose in units normalized to the incident energy fluence with phantom scatter intrinsically modeled. Output factors ca...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596859

    authors: Ahnesjö A,Knöös T,Montelius A

    更新日期:1992-03-01 00:00:00

  • SU-E-J-84: Investigating the Use of Deformable Algorithms to Register and Accumulate Dose to the Spinal Cord for Head-And-Neck Radiotherapy Patients.

    abstract:PURPOSE:Mega-voltage cone-beam CT (MVCBCT) imaging can be used to monitor changes in neck flexion and calculate the true spinal cord dose during radiotherapy. To sum the dose over multiple fractions and compare with the planned dose requires deformable image registration. This study investigates the accuracy of deforma...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734919

    authors: Ueda U,Chen J,Kirby N,Quivey J,Yom S,Pouliot J

    更新日期:2012-06-01 00:00:00

  • Real-time 4DMRI-based internal target volume definition for moving lung tumors.

    abstract:PURPOSE:In photon radiotherapy, respiratory-induced target motion can be accounted for by internal target volumes (ITV) or mid-ventilation target volumes (midV) defined on the basis of four-dimensional computed tomography (4D-CT). Intrinsic limitations of these approaches can result in target volumes that are not repre...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14023

    authors: Rabe M,Thieke C,Düsberg M,Neppl S,Gerum S,Reiner M,Nicolay NH,Schlemmer HP,Debus J,Dinkel J,Landry G,Parodi K,Belka C,Kurz C,Kamp F

    更新日期:2020-04-01 00:00:00

  • Potential of high-Z contrast agents in clinical contrast-enhanced computed tomography.

    abstract:PURPOSE:Currently, only iodine- and barium-based contrast media (CM) are used in clinical contrast-enhanced computed tomography (CE-CT). High-Z metals would produce a higher contrast at equal mass density for the x-ray spectra used in clinical CT. Using such materials might allow for significant dose reductions in CE-C...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3658738

    authors: Nowak T,Hupfer M,Brauweiler R,Eisa F,Kalender WA

    更新日期:2011-12-01 00:00:00

  • Experimental study of the relationship between the base impedance and its time derivative in impedance plethysmography.

    abstract::Transthoracic electrical impedance Z consists of a constant baseline component Z0 and the time variable component delta Z such that Z = Z0 + delta Z. The first time derivative of Z has a negative peak, the magnitude of which is (dZ/dt)min. Measurements of 170 volunteers show that (dZ/dt)min is a function of the consta...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594910

    authors: Djordjevich L,Sadove MS

    更新日期:1981-01-01 00:00:00

  • Changes realized from extended bit-depth and metal artifact reduction in CT.

    abstract:PURPOSE:High-Z material in computed tomography (CT) yields metal artifacts that degrade image quality and may cause substantial errors in dose calculation. This study couples a metal artifact reduction (MAR) algorithm with enhanced 16-bit depth (vs standard 12-bit) to quantify potential gains in image quality and dosim...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4805102

    authors: Glide-Hurst C,Chen D,Zhong H,Chetty IJ

    更新日期:2013-06-01 00:00:00

  • The impact of small motion on the visualization of coronary vessels and lesions in cardiac CT: A simulation study.

    abstract:PURPOSE:Coronary x-ray computed tomography angiography (CCTA) is used to non-invasively assess coronary artery geometry and has, combined with computational modeling, demonstrated the potential to identify physiologically significant lesions. These measurements require robust and accurate coronary imaging and delineati...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12295

    authors: Contijoch F,Stayman JW,McVeigh ER

    更新日期:2017-07-01 00:00:00

  • SU-E-J-11: Characterization of Interfractioanal Anatomical Variations in Post-Operative Radiation Therapy for Prostate Bed.

    abstract:PURPOSE:To quantitatively characterize the interfractional anatomic variations in post-operative radiation therapy (RT) for prostate bed, so that appropriate strategy that can fully address these variations can be developed. METHODS:A total of 102 daily pre-treatment CT acquired using an in-room CT (CTVision, Siemens)...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734844

    authors: Liu F,Ahunbay E,Christian R,Lawton C,Wang D,Li X

    更新日期:2012-06-01 00:00:00

  • Technical Note: Evaluation of a 160-mm/256-row CT scanner for whole-heart quantitative myocardial perfusion imaging.

    abstract:PURPOSE:The authors investigated the performance of a recently introduced 160-mm/256-row CT system for low dose quantitative myocardial perfusion (MP) imaging of the whole heart. This platform is equipped with a gantry capable of rotating at 280 ms per full cycle, a second generation of adaptive statistical iterative r...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4957389

    authors: So A,Imai Y,Nett B,Jackson J,Nett L,Hsieh J,Wisenberg G,Teefy P,Yadegari A,Islam A,Lee TY

    更新日期:2016-08-01 00:00:00

  • SU-E-T-203: Development of a QA Software Tool for Automatic Verification of Plan Data Transfer and Delivery.

    abstract:PURPOSE:Consistency verification between the data from treatment planning system (TPS), record and verification system (R&V), and delivered recorder with visual inspection is time consuming and subject to human error. The purpose of this work is to develop a software tool to automatically perform such verifications. M...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735263

    authors: Chen G,Li X

    更新日期:2012-06-01 00:00:00

  • Optimized low-kV spectrum of dual-energy CT equipped with high-kV tin filtration for electron density measurements.

    abstract:PURPOSE:This paper describes the low-kV spectral optimization of dual-energy CT (DECT) equipped with high-kV tin filtration for the quantitative acquisition of electron density information, which is essential for treatment planning in radiotherapy. In addition, an analytical DECT image simulation was preliminarily perf...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3584200

    authors: Saito M

    更新日期:2011-06-01 00:00:00