Optimizing cone beam CT scatter estimation in egs_cbct for a clinical and virtual chest phantom.

Abstract:

PURPOSE:Cone beam computed tomography (CBCT) image quality suffers from contamination from scattered photons in the projection images. Monte Carlo simulations are a powerful tool to investigate the properties of scattered photons.egs_cbct, a recent EGSnrc user code, provides the ability of performing fast scatter calculations in CBCT projection images. This paper investigates how optimization of user inputs can provide the most efficient scatter calculations. METHODS:Two simulation geometries with two different x-ray sources were simulated, while the user input parameters for the efficiency improving techniques (EITs) implemented inegs_cbct were varied. Simulation efficiencies were compared to analog simulations performed without using any EITs. Resulting scatter distributions were confirmed unbiased against the analog simulations. RESULTS:The optimal EIT parameter selection depends on the simulation geometry and x-ray source. Forced detection improved the scatter calculation efficiency by 80%. Delta transport improved calculation efficiency by a further 34%, while particle splitting combined with Russian roulette improved the efficiency by a factor of 45 or more. Combining these variance reduction techniques with a built-in denoising algorithm, efficiency improvements of 4 orders of magnitude were achieved. CONCLUSIONS:Using the built-in EITs inegs_cbct can improve scatter calculation efficiencies by more than 4 orders of magnitude. To achieve this, the user must optimize the input parameters to the specific simulation geometry. Realizing the full potential of the denoising algorithm requires keeping the statistical uncertainty below a threshold value above which the efficiency drops exponentially.

journal_name

Med Phys

journal_title

Medical physics

authors

Thing RS,Mainegra-Hing E

doi

10.1118/1.4881142

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

071902

issue

7

eissn

0094-2405

issn

2473-4209

journal_volume

41

pub_type

杂志文章
  • Automated matching and segmentation of lymphoma on serial CT examinations.

    abstract::In patients with lymphoma, identification and quantification of the tumor extent on serial CT examinations is critical for assessing tumor response to therapy. In this paper, we present a computer method to automatically match and segment lymphomas in follow-up CT images. The method requires that target lymph nodes in...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2404617

    authors: Yan J,Zhao B,Curran S,Zelenetz A,Schwartz LH

    更新日期:2007-01-01 00:00:00

  • SU-E-J-139: Feasibility of Using EPID for Real-Time Target Localization during Treatment.

    abstract:PURPOSE:This study aims to investigate the feasibility of using the images of the treatment fields acquired by an electronic portal imaging device (EPID) for real-time target localization. METHODS:Forty one patients treated with IMRT and RapidArc were recruited in this study including 37 prostate patients and 4 lung p...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734975

    authors: Xu Q,Lin M,Chen X,Tong X,Fan J,Dong Z,Chen L,Ma C

    更新日期:2012-06-01 00:00:00

  • Technical note: A novel boundary condition using contact elements for finite element based deformable image registration.

    abstract::Deformable image registration is an important tool for image-guided radiotherapy. Physics-model-based deformable image registration using finite element analysis is one of the methods currently being investigated. The calculation accuracy of finite element analysis is dependent on given boundary conditions, which are ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1774131

    authors: Zhang T,Orton NP,Mackie TR,Paliwal BR

    更新日期:2004-09-01 00:00:00

  • Technical Note: exploring the limit for the conversion of energy-subtracted CT number to electron density for high-atomic-number materials.

    abstract:PURPOSE:For accurate tissue inhomogeneity correction in radiotherapy treatment planning, the authors had previously proposed a novel conversion of the energy-subtracted CT number to an electron density (ΔHU-ρe conversion), which provides a single linear relationship between ΔHU and ρe over a wide ρe range. The purpose ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4881327

    authors: Saito M,Tsukihara M

    更新日期:2014-07-01 00:00:00

  • Potential increase in biological effectiveness from field timing optimization for stereotactic body radiation therapy.

    abstract:PURPOSE:Stereotactic body radiation therapy (SBRT) is a radiotherapy technique which uses high dose fractions with multiple coplanar and noncoplanar beams. Due to the large fractional doses, treatments are typically protracted and there are more fields than in conventional radiation treatment schemes. The effect of tem...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4709605

    authors: Schmitt JD,Warren GW,Wang IZ

    更新日期:2012-06-01 00:00:00

  • A neural network approach for fast, automated quantification of DIR performance.

    abstract:PURPOSE:A critical step in adaptive radiotherapy (ART) workflow is deformably registering the simulation CT with the daily or weekly volumetric imaging. Quantifying the deformable image registration accuracy under these circumstances is a complex task due to the lack of known ground-truth landmark correspondences betwe...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12321

    authors: Neylon J,Min Y,Low DA,Santhanam A

    更新日期:2017-08-01 00:00:00

  • Dosimetric impact of motion in free-breathing and gated lung radiotherapy: a 4D Monte Carlo study of intrafraction and interfraction effects.

    abstract::The purpose of this study was to investigate if interfraction and intrafraction motion in free-breathing and gated lung IMRT can lead to systematic dose differences between 3DCT and 4DCT. Dosimetric effects were studied considering the breathing pattern of three patients monitored during the course of their treatment ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2821704

    authors: Seco J,Sharp GC,Wu Z,Gierga D,Buettner F,Paganetti H

    更新日期:2008-01-01 00:00:00

  • Respiratory phase alignment improves blood-flow quantification in Rb82 PET myocardial perfusion imaging.

    abstract:PURPOSE:Positron emission tomography (PET) is considered the gold standard for measuring myocardial blood flow in vivo but it is known that respiratory motion can lead to misalignment of the PET and computed tomography (CT) data sets and introduce artifacts in the CT-based attenuation correction (AC) of images. In addi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4788669

    authors: Pourmoghaddas A,Klein R,deKemp RA,Wells RG

    更新日期:2013-02-01 00:00:00

  • The management of imaging dose during image-guided radiotherapy: report of the AAPM Task Group 75.

    abstract::Radiographic image guidance has emerged as the new paradigm for patient positioning, target localization, and external beam alignment in radiotherapy. Although widely varied in modality and method, all radiographic guidance techniques have one thing in common--they can give a significant radiation dose to the patient....

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2775667

    authors: Murphy MJ,Balter J,Balter S,BenComo JA Jr,Das IJ,Jiang SB,Ma CM,Olivera GH,Rodebaugh RF,Ruchala KJ,Shirato H,Yin FF

    更新日期:2007-10-01 00:00:00

  • The use of a priori information in the detection of mammographic microcalcifications to improve their classification.

    abstract::In this work, we present a calcification-detection scheme that automatically localizes calcifications in a previously detected cluster in order to generate the input for a cluster-classification scheme developed in the past. The calcification-detection scheme makes use of three pieces of a priori information: the loca...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1559884

    authors: Salfity MF,Nishikawa RM,Jiang Y,Papaioannou J

    更新日期:2003-05-01 00:00:00

  • Proton magnetic resonance spectroscopy in the brain: report of AAPM MR Task Group #9.

    abstract::AAPM Magnetic Resonance Task Group #9 on proton magnetic resonance spectroscopy (MRS) in the brain was formed to provide a reference document for acquiring and processing proton (1H) MRS acquired from brain tissue. MRS is becoming a common adjunct to magnetic resonance imaging (MRI), especially for the differential di...

    journal_title:Medical physics

    pub_type: 指南,杂志文章,实务指引,评审

    doi:10.1118/1.1501822

    authors: Drost DJ,Riddle WR,Clarke GD,AAPM MR Task Group #9.

    更新日期:2002-09-01 00:00:00

  • Computerized characterization of masses on mammograms: the rubber band straightening transform and texture analysis.

    abstract::A new rubber band straightening transform (RBST) is introduced for characterization of mammographic masses as malignant or benign. The RBST transforms a band of pixels surrounding a segmented mass onto the Cartesian plane (the RBST image). The border of a mammographic mass appears approximately as a horizontal line, a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598228

    authors: Sahiner B,Chan HP,Petrick N,Helvie MA,Goodsitt MM

    更新日期:1998-04-01 00:00:00

  • Investigating the feasibility of photon-counting K-edge imaging at high x-ray fluxes using nonlinearity corrections.

    abstract:PURPOSE:Pulse pileup occurring at high x-ray fluxes can severely degrade the energy resolution provided by a photon counting detector, which can represent a problem in spectroscopic CT when performing quantitative material discrimination tasks. As the effects of pileup can be most easily seen as a degradation of a dete...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4820535

    authors: Rink K,Oelfke U,Fiederle M,Zuber M,Koenig T

    更新日期:2013-10-01 00:00:00

  • Image reconstruction algorithm for a rotating slat collimator.

    abstract::A slat collimator in single photon emission computed tomography consists of a set of parallel slats. As the collimator spins, the detector measures a one-dimensional projection data set. A complete data set can be obtained by rotating the detector/collimator assembly around the object (patient) while the collimator sp...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1485057

    authors: Zeng GL,Gagnon D,Matthews CG,Kolthammer JA,Radachy JD,Hawkins WG

    更新日期:2002-07-01 00:00:00

  • SU-E-T-459: Radiobiological Evaluation of Implant Duration and Radionuclide Selection for COMS Eye Plaque Brachytherapy Using an Objective Function.

    abstract:PURPOSE:The biologically effective dose (BED) of temporary brachytherapy treatments is a function of both chosen radionuclide (R) and implant duration (T). This study endeavored to evaluate BED delivered to the tumor volume and surrounding ocular structures as a function of plaque position (P), prescription dose, R, an...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735548

    authors: Gagne N,Rivard M

    更新日期:2012-06-01 00:00:00

  • Investigating CT to CBCT image registration for head and neck proton therapy as a tool for daily dose recalculation.

    abstract:PURPOSE:Intensity modulated proton therapy (IMPT) of head and neck (H&N) cancer patients may be improved by plan adaptation. The decision to adapt the treatment plan based on a dose recalculation on the current anatomy requires a diagnostic quality computed tomography (CT) scan of the patient. As gantry-mounted cone be...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4908223

    authors: Landry G,Nijhuis R,Dedes G,Handrack J,Thieke C,Janssens G,Orban de Xivry J,Reiner M,Kamp F,Wilkens JJ,Paganelli C,Riboldi M,Baroni G,Ganswindt U,Belka C,Parodi K

    更新日期:2015-03-01 00:00:00

  • Dose sculpting with generalized equivalent uniform dose.

    abstract::With intensity-modulated radiotherapy (IMRT), a variety of user-defined dose distribution can be produced using inverse planning. The generalized equivalent uniform dose (gEUD) has been used in IMRT optimization as an alternative objective function to the conventional dose-volume-based criteria. The purpose of this st...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1897464

    authors: Wu Q,Djajaputra D,Liu HH,Dong L,Mohan R,Wu Y

    更新日期:2005-05-01 00:00:00

  • Dosimetric accuracy of Kodak EDR2 film for IMRT verifications.

    abstract::Patient-specific intensity-modulated radiotherapy (IMRT) verifications require an accurate two-dimensional dosimeter that is not labor-intensive. We assessed the precision and reproducibility of film calibrations over time, measured the elemental composition of the film, measured the intermittency effect, and measured...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1852791

    authors: Childress NL,Salehpour M,Dong L,Bloch C,White RA,Rosen II

    更新日期:2005-02-01 00:00:00

  • An improved bolus configuration for commercial multielement ultrasound and microwave hyperthermia systems.

    abstract::A simple modification is presented for two commercially available hyperthermia applicators which dramatically improves the regulation and dynamic control of the temperature at the bolus/tissue interface. This alteration requires the addition of a variable speed pump, bubble trap, simple heat exchanger, and a few minor...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597196

    authors: Diederich CJ,Stauffer PR,Bozzo D

    更新日期:1994-09-01 00:00:00

  • Attenuation, scattering, and absorption of ultrasound in the skull bone.

    abstract:PURPOSE:Measured values of ultrasound attenuation in bone represent a combination of different loss mechanisms. As a wave is transmitted from a fluid into bone, reflections occur at the interface. In the bone, mode conversion occurs between longitudinal and shear modes and the mechanical wave is scattered by its comple...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3668316

    authors: Pinton G,Aubry JF,Bossy E,Muller M,Pernot M,Tanter M

    更新日期:2012-01-01 00:00:00

  • Poster - Thurs Eve-32: Dose errors related to the treatment couch.

    abstract::Modern radiotherapy linacs often use carbon fibre for their couch tops due to its radio translucent properties. Beam attenuation by the couches is often ignored during planning and MU calculation. This work examines beam attenuation and loss of "skin sparing" (dose build up region) when various photon beams transit ei...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2965951

    authors: Niedbala M,Nyiri B,Gerig L

    更新日期:2008-07-01 00:00:00

  • Comparison of three strategies in management of independent movement of the prostate and pelvic lymph nodes.

    abstract:PURPOSE:Concurrent irradiation of the prostate and pelvic lymph nodes is technically challenging due to treating one moving target and one immobile target. The purposes of this article are to propose a new management strategy and to compare this strategy to the conventional isocenter shift method and the previously pro...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3480505

    authors: Xia P,Qi P,Hwang A,Kinsey E,Pouliot J,Roach M 3rd

    更新日期:2010-09-01 00:00:00

  • Dosimetric properties of radiophotoluminescent glass detector in low-energy photon beams.

    abstract:PURPOSE:A radiophotoluminescent glass rod dosimeter (RGD) has recently become commercially available. It is being increasingly used for dosimetry in radiotherapy to measure the absorbed dose including scattered low-energy photons on the body surface of a patient and for postal dosimetry audit. In this article, the dosi...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4747261

    authors: Kadoya N,Shimomura K,Kitou S,Shiota Y,Fujita Y,Dobashi S,Takeda K,Jingu K,Matsushita H,Namito Y,Ban S,Koyama S,Tabushi K

    更新日期:2012-10-01 00:00:00

  • Three-dimensional dose reconstruction of breast cancer treatment using portal imaging.

    abstract::In this study, we present an algorithm for three-dimensional (3-D) dose reconstruction using portal images obtained with an electronic portal imaging device (EPID). For this purpose an algorithm for 2-D dose reconstruction, which was previously developed in our institution, was adapted. The external contour of the pat...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1589496

    authors: Louwe RJ,Damen EM,van Herk M,Minken AW,Törzsök O,Mijnheer BJ

    更新日期:2003-09-01 00:00:00

  • Gradient corrections for reference dosimetry using Farmer-type ionization chambers in single-layer scanned proton fields.

    abstract:PURPOSE:The local depth dose gradient and the displacement correction factor for Farmer-type ionization chambers are quantified for reference dosimetry at shallow depth in single-layer scanned proton fields. METHOD:Integrated radial profiles as a function of depth (IRPDs) measured at three proton therapy centers were ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.14554

    authors: Palmans H,Medin J,Trnková P,Vatnitsky S

    更新日期:2020-12-01 00:00:00

  • MO-F-BRCD-01: Stereotactic Body Radiation Therapy: Updates on Clinical, Biological, and Physics/QA:SBRT (Part 1): Biological and Clinical Updates.

    abstract::Stereotactic Body Radiation Therapy (SBRT) is an important form of cancer therapy with increasingly broad application across a spectrum of tumor types in primary and metastatic settings. In this presentation the radiation biology, clinical experience from various trials, and cautionary updates on normal tissue toleran...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735812

    authors: Read P

    更新日期:2012-06-01 00:00:00

  • Vision 20/20: Molecular-guided surgical oncology based upon tumor metabolism or immunologic phenotype: Technological pathways for point of care imaging and intervention.

    abstract::Surgical guidance with fluorescence has been demonstrated in individual clinical trials for decades, but the scientific and commercial conditions exist today for a dramatic increase in clinical value. In the past decade, increased use of indocyanine green based visualization of vascular flow, biliary function, and tis...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4951732

    authors: Pogue BW,Paulsen KD,Samkoe KS,Elliott JT,Hasan T,Strong TV,Draney DR,Feldwisch J

    更新日期:2016-06-01 00:00:00

  • Improvement of off-axis SABR plan verification results by using adapted dose reconstruction algorithms for the Octavius 4D system.

    abstract:PURPOSE:Stereotactic ablative body radiotherapy (SABR) for lung patients can be performed with volumetric-modulated arc therapy (VMAT) plans using off-axis target geometry to allow treatment in their CBCT verified position. For patient-specific quality assurance measurements using the PTW Octavius 4D phantom (PTW, Frei...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12805

    authors: Jeevanandam P,Agnew CE,Irvine DM,McGarry CK

    更新日期:2018-04-01 00:00:00

  • Planning strategies in volumetric modulated are therapy for breast.

    abstract:PURPOSE:In breast radiotherapy with intensity modulation, it is a well established practice to extend the dose fluence outside the limit of the body contour to account for small changes in size and position of the target and the rest of the tissues due to respiration or to possible oedema. A simple approach is not appl...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3598442

    authors: Giorgia N,Antonella F,Alessandro C,Eugenio V,Luca C

    更新日期:2011-07-01 00:00:00

  • A boundary element approach for image-guided near-infrared absorption and scatter estimation.

    abstract::Multimodality NIR spectroscopy systems offer the possibility of region-based vascular and molecular characterization of tissue in vivo. However, computationally efficient 3D image reconstruction algorithms specific to these image-guided systems currently do not exist. Image reconstruction is often based on finite-elem...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2795832

    authors: Srinivasan S,Pogue BW,Carpenter C,Yalavarthy PK,Paulsen K

    更新日期:2007-11-01 00:00:00