Atrial natriuretic peptides stimulate renal gluconeogenesis.

abstract：:Colorectal cancer is one of the leading causes of cancer-related deaths. Due to relapse after current therapy regimens, cancer stem cells (CSCs) are being studied to target this small tumor-initiating population. Anterior gradient 2 (AGR2), a disulfide isomerase protein, is a well-known pro-oncogenic/metastatic oncoge...

journal_title：Biochemical and biophysical research communications

authors： Dahal Lamichane B,Jung SY,Yun J,Kang S,Kim DY,Lamichane S,Kim YJ,Park JH,Jang WB,Ji ST,Dehua L,Ha JS,Kim YH,Kwon SM

更新日期：2019-08-06 00:00:00

abstract：:Interleukin 6 is a cytokine with growth and differentiation activities on a number of cell types. Human articular chondrocytes produce interleukin 6 and this production appears to be constitutive but can be stimulated in a dose-dependent manner by interleukin 1. Other stimulators of interleukin 6 production in chondro...

journal_title：Biochemical and biophysical research communications

authors： Bunning RA,Russell RG,Van Damme J

更新日期：1990-02-14 00:00:00

abstract：:Terminal differentiation of myocytes involves withdrawal from the cell cycle, induction of myogenin expression, and finally formation of myotubes. To study the factors that regulate the initial phase of muscle differentiation, we analyzed the binding activities of transcription factors AP-1, Sp-1, and NF-kappa B in L6...

journal_title：Biochemical and biophysical research communications

authors： Lehtinen SK,Rahkila P,Helenius M,Korhonen P,Salminen A

更新日期：1996-12-04 00:00:00

abstract：:Platelets are an important place for the storage of angiogenic factors, such as vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor (BDNF). The present study aims to investigate the interaction between BDNF-TrkB pathway and platelet activation during tumor development. In an orthotopic hepa...

journal_title：Biochemical and biophysical research communications

authors： Yang ZF,Ho DW,Lau CK,Tam KH,Lam CT,Poon RT,Fan ST

更新日期：2006-08-04 00:00:00

abstract：:The cellular actions of nerve growth factor (NGF) involve regulation of protein phosphorylation. In PC-12 pheochromocytoma cells, exposure of [125I]NGF followed by crosslinking indicates that the ligand binds to two discreet receptors, the previously described 75 kd protein, as well as the trk proto-oncogene product p...

journal_title：Biochemical and biophysical research communications

authors： Ohmichi M,Decker SJ,Pang L,Saltiel AR

更新日期：1991-08-30 00:00:00

abstract：:Neocarzinostatin is a radiomimetic antibiotic with a potent cytotoxic effect which elicits a hypersensitive response in human cells homozygous or heterozygous for the gene for ataxia-telangiectasia. The extent and the time course of potentially lethal damage repair and sublethal damage repair following neocarzinostati...

journal_title：Biochemical and biophysical research communications

authors： Shiloh Y,Tabor E,Becker Y

更新日期：1983-01-27 00:00:00

abstract：:The enzymatic methylation of chemically alkylated DNA and of poly(dG-dC) X poly(dG-dC) by beef brain DNA(cytosine-5-)-methyltransferase have been tested. The alkylation by dimethylsulfate, which yields mostly 7 methylguanine (m7G) and 3 methyladenine (m3A) do not affect the enzymatic methylation. The dimethylsulfate a...

journal_title：Biochemical and biophysical research communications

authors： Pfohl-Leszkowicz A,Boiteux S,Laval J,Keith G,Dirheimer G

更新日期：1983-10-31 00:00:00

abstract：:Translationally controlled tumor protein (TCTP) is often designated as a stress-related protein because of its highly regulated expression in stress conditions. Following a thermal shock, TCTP expression is highly upregulated in a variety of cells. However, at present it is not known whether this upregulation has any ...

journal_title：Biochemical and biophysical research communications

authors： Gnanasekar M,Dakshinamoorthy G,Ramaswamy K

更新日期：2009-08-21 00:00:00

abstract：:Cytotoxic lymphocytes utilize granule associated serine proteases (granzymes) and perforin to induce apoptosis. Although the importance of granzyme B has been established by gene ablation experiments, biochemical events initiated by the granzyme remain enigmatic. We show here that exposure of Jurkat cells to granzyme ...

journal_title：Biochemical and biophysical research communications

authors： Froelich CJ,Hanna WL,Poirier GG,Duriez PJ,D'Amours D,Salvesen GS,Alnemri ES,Earnshaw WC,Shah GM

更新日期：1996-10-23 00:00:00

abstract：:Special AT-rich sequence-binding protein (SATB) plays a critical role in bone generation and osteoblast differentiation. In the present study, the differentially expressed genes by SATB2 overexpression were analyzed in MC3T3-E1 osteoblast-like cells using Alizarin red S staining, wound healing assay and Agilent's Huma...

journal_title：Biochemical and biophysical research communications

authors： Kim IS,Jeong SJ,Kim SH,Jung JH,Park YG,Kim SH

更新日期：2012-01-13 00:00:00

abstract：:Subpeptin JM4-A and subpeptin JM4-B are two novel antimicrobial peptides produced by Bacillus subtilis JM4. To identify putative genes involved in their production, degenerate PCR primers targeted to conserved motifs of nonribosomal peptide synthetases (NRPSs) were used. A resulting 1.2 kb PCR product had high sequenc...

journal_title：Biochemical and biophysical research communications

authors： Wu S,Zhong J,Huan L

更新日期：2006-06-16 00:00:00

abstract：:The role of microRNAs (miRNAs) in how microbiota influence the host intestinal immune system is not fully understood. We compared the expression profiles of miRNAs and mRNAs in lamina propria leukocytes (LPL) in the large intestines of germ-free (GF) and specific pathogen-free (SPF) mice. Microarray analysis revealed ...

journal_title：Biochemical and biophysical research communications

authors： Ohsaka F,Karatsu Y,Kadota Y,Tochio T,Takemura N,Sonoyama K

更新日期：2021-01-01 00:00:00

abstract：:To elucidate the role of ornithine decarboxylase (ODC) in cancer cell invasion, we have compared the invasiveness of mouse mammary carcinoma, FM3A and its variant cell line, EXOD, which overproduces ODC. We have found that EXOD cells showed about 5.6-fold more invasiveness through a reconstituted basement membrane (Ma...

journal_title：Biochemical and biophysical research communications

authors： Kubota S,Yamada T,Kamei S,Seyama Y

更新日期：1995-03-28 00:00:00

abstract：:Max binding protein (MNT) is a member of the Myc/Max/Mad network that plays a role in cell proliferation, differentiation and apoptosis. We previously observed that MNT was differentially expressed in hepatocellular carcinoma (HCC) and interacted with Nck1 by 2-DE. Nck family adaptor proteins function to couple tyrosi...

journal_title：Biochemical and biophysical research communications

authors： Wu J,Zhou Q,Wang Y,Zhou X,Li J

更新日期：2012-02-03 00:00:00

abstract：:The outward K+ current induced by step depolarization of freshly dispersed myocytes of guinea-pig taenia coli decreased about 80% upon treatment with 3 mM tetraethylammonium chloride (TEA). Isoproterenol (ISO, 2-5 microM) restored it to a large extent. This restoration did not occur in the presence of propranolol (2 m...

journal_title：Biochemical and biophysical research communications

authors： Fan SF,Wang S,Kao CY

更新日期：1994-05-30 00:00:00

abstract：:Lymph node metastasis (LNM) is a critical cause for disease progression and treatment failure in cervical cancer. However, the mechanism underlying cervical cancer LNM remains unclear. In this study, HN1 was found to be dramatically upregulated in cervical cancer and patients with higher HN1 expression are more likely...

journal_title：Biochemical and biophysical research communications

authors： Chen J,Qiu J,Li F,Jiang X,Sun X,Zheng L,Zhang W,Li H,Wu H,Ouyang Y,Chen X,Lin C,Song L,Zhang Y

更新日期：2020-09-10 00:00:00

abstract：:Professional phagocytes contain a unique NADPH oxidase responsible for the production of microbicidal oxidants. Activation of this oxidase requires participation of cytosolic and membrane proteins, but the interactions of these components are incompletely understood. Patients with autosomal recessive Chronic Granuloma...

journal_title：Biochemical and biophysical research communications

authors： Levy R,Malech HL,Rotrosen D

更新日期：1990-08-16 00:00:00

abstract：:Gaucher disease (GD) is the most common lysosomal storage disorder (LSD) and is divided into three phenotypes, I, II, and III. Type I is the most prevalent form and has its onset in adulthood. The degree of endoplasmic reticulum (ER) stress is one of the factors that determine GD severity. It has recently been reporte...

journal_title：Biochemical and biophysical research communications

authors： Lee YJ,Kim SJ,Heo TH

更新日期：2011-09-23 00:00:00

abstract：:The cardioprotective effect of SUN 1165, a novel sodium channel blocker, was investigated on ischemic myocardium. Nineteen anesthetized dogs were subjected to 2 hours coronary occlusion, and divided into 2 groups. In the control group, physiological saline was infused. In the SUN 1165 group, 2 mg/kg of SUN 1165 was in...

journal_title：Biochemical and biophysical research communications

authors： Sugiyama S,Hanaki Y,Ogawa T,Hieda N,Taki K,Ozawa T

更新日期：1988-12-15 00:00:00

abstract：:The control of HIV-1 gene expression depends upon interaction of Tat with the trans-activation responsive (TAR) element present at the 5' end of all HIV-1 transcripts. The TAR sequence forms a stable hair-pin structure that binds Tat and several cellular factors in vitro. In the absence of Tat, TAR acts as a transcrip...

journal_title：Biochemical and biophysical research communications

authors： Kaczmarski W,Khan SA

更新日期：1993-10-29 00:00:00

abstract：:The hyperpolarization-activated cation current I(h) is an important regulator of neuronal excitability and may contribute to the properties of the dentate gyrus granule (DGG) cells, which constitute the input site of the canonical hippocampal circuit. Here, we investigated changes in I(h) in DGG cells in human tempora...

journal_title：Biochemical and biophysical research communications

authors： Surges R,Kukley M,Brewster A,Rüschenschmidt C,Schramm J,Baram TZ,Beck H,Dietrich D

更新日期：2012-03-30 00:00:00

abstract：:In quiescent cultures of rabbit aortic smooth muscle cells, whole blood serum-induced DNA synthesis was inhibited markedly by protein kinase C-activating 12-O-tetradecanoyl-phorbol-13-acetate (TPA) and phorbol-12, 13-dibutyrate (PDBu), cyclic AMP-derivatives, such as dibutyryl cyclic AMP (Bt2cAMP) and 8-bromo-cyclic A...

journal_title：Biochemical and biophysical research communications

authors： Fukumoto Y,Kawahara Y,Kariya K,Araki S,Fukuzaki H,Takai Y

更新日期：1988-11-30 00:00:00

abstract：:Interaction of camel lens zeta-crystallin with aspirin was investigated by activity and fluorescence measurements. Aspirin minimally inhibited the oxidoreductase activity of the enzyme and weakly quenched its fluorescence. However, significant fluorescence quenching of zeta-crystallin coincided with the appearance of ...

journal_title：Biochemical and biophysical research communications

authors： Bazzi MD

更新日期：2002-04-26 00:00:00

abstract：:The one-electron reduction product of 1-methyl-4-phenyl-2,3-dihydropyridinium ion has been generated by pulse radiolysis and its absorption spectrum recorded. This radical was found to decay by second-order kinetics (2k = 9.5 x 10(8) M-1 s-1) to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenyl-2,3-di...

journal_title：Biochemical and biophysical research communications

authors： Chacón JN,Chedekel MR,Land EJ,Truscott TG

更新日期：1989-01-16 00:00:00

abstract：:A low molecular weight protein (approximately 25,000 D) exhibiting a yellow fluorescence emission peaking at approximately 540 nm was isolated from Vibrio fischeri (strain Y-1) and purified to apparent homogeneity. FMN is the chromophore, but it exhibits marked red shifts in both the absorption (lambda max = 380, 460 ...

journal_title：Biochemical and biophysical research communications

authors： Macheroux P,Schmidt KU,Steinerstauch P,Ghisla S,Colepicolo P,Buntic R,Hastings JW

更新日期：1987-07-15 00:00:00

abstract：:Genetic mutation is one of the causative factors for idiopathic progressive hearing loss. A patient with late-onset, moderate, and high-frequency hearing loss was found to have a novel, heterozygous KCNQ4 mutation, c.806_808delCCT, which led to a p.Ser260del located between S5 and the pore helix (PH). Molecular modeli...

journal_title：Biochemical and biophysical research communications

authors： Watabe T,Matsunaga T,Namba K,Mutai H,Inoue Y,Ogawa K

更新日期：2013-03-15 00:00:00

abstract：:The adipose tissue of genetically obese Zucker rats is characterized by coordinated tissue specific overtranscription of a subset of genes related to lipid storage such as Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH). We show that CCAAT/Enhancer Binding Protein alpha (C/EBP alpha) is an activator of GAPDH proximal...

journal_title：Biochemical and biophysical research communications

authors： Rolland V,Le Liepvre X,Houbiguian ML,Lavau M,Dugail I

更新日期：1995-02-15 00:00:00

abstract：:We have investigated the effect of PARP gene inactivation on the expression of wild-type (wt) p53 protein. Using immortalized fibroblasts from control and PARP knock-out mice we have found by immunoblotting with the PAb421 antibody a profound decrease of the p53 expression to a barely detectable level in PARP knock-ou...

journal_title：Biochemical and biophysical research communications

authors： Schmid G,Wang ZQ,Wesierska-Gadek J

更新日期：1999-02-16 00:00:00

abstract：:Genes for the human vacuolar type H(+)-ATPase proteolipid (16-kDa) subunit were cloned and their nucleotide sequences were determined. Comparison of the deduced sequences indicated that at least four genes including pseudogenes are present in the human genome. One of them corresponded to that for the 16-kDa subunit ex...

journal_title：Biochemical and biophysical research communications

authors： Hasebe M,Hanada H,Moriyama Y,Maeda M,Futai M

更新日期：1992-03-16 00:00:00

abstract：:The aim of this work was to characterize folates modified by ONOO(-) and HOCl and to evaluate the binding capacity of folates modified by ONOO(-) to folate receptor alpha and beta. For the modification of folate by ONOO(-), folic acid was reacted with the combination of PMA activated PMN and PAPA NONOate or chemically...

journal_title：Biochemical and biophysical research communications

authors： Nakamura M,Nagayoshi R,Ijiri K,Nakashima-Matsushita N,Takeuchi T,Matsuyama T

更新日期：2002-10-11 00:00:00