Enzymatic methylation of chemically alkylated DNA and poly(dG-dC) X poly(dG-dC) in B and Z forms.

abstract：:To help clarify bases for the molecular weight and surface charge heterogeneities of forms of somatic angiotensin converting enzyme (ACE), we examined for differences in N-glycosylation. ACE preparations purified from human, guinea pig, rat and rabbit tissues were found to be heterogeneous in terms of numbers of N-gly...

journal_title：Biochemical and biophysical research communications

authors： Ripka JE,Ryan JW,Valido FA,Chung AY,Peterson CM,Urry RL

更新日期：1993-10-29 00:00:00

abstract：:Receptor tyrosine kinase EphA7 is specifically expressed in otic region in Xenopus early development. However, its role in otocyst development remains unknown. Knockdown of EphA7 by a specific morpholino oligonucleotide (MO) reduced the size of the otocyst and triggered otic epithelial cell extrusion. Interestingly, E...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Sun J,Wang Z,Li C,Mao B

更新日期：2020-05-28 00:00:00

abstract：:BIK, a member of the Bcl-2 family, has been reported to induce cell apoptosis but the underlying mechanisms are not well delineated. We used siRNA targeting caspase-12 to examine the effect of caspase-12 on apoptosis induced by BIK. In this study, we show that caspase-12 was activated by BIK. With caspase-12 knocked d...

journal_title：Biochemical and biophysical research communications

authors： Zhao X,Sun Y,Yu H,Ye L,Zhang L,Lu J,Yuan Y,Qian G,Ge S

更新日期：2007-08-10 00:00:00

abstract：:To understand the molecular mechanisms involved in preleukemia, the suppression subtractive hybridization method was used in a murine radiation-induced thymic lymphoma model. Seventeen mRNAs overexpressed in preleukemic thymuses were identified: mouse laminin binding protein (p40/37LBP), E25 protein, Rattus norvegicus...

journal_title：Biochemical and biophysical research communications

authors： Verlaet M,Deregowski V,Denis G,Humblet C,Stalmans MT,Bours V,Castronovo V,Boniver J,Defresne MP

更新日期：2001-04-27 00:00:00

abstract：:A monoclonal antibody (mAb) 25B1 directed against fetal bovine-serum acetylcholinesterase (FBS AChE) was used to examine the ability of the cholinergic enzyme to promote the assembly of amyloid-beta peptides (A beta) into Alzheimerś fibrils. This mAb binds to the peripheral anionic site of the enzyme and allostericall...

journal_title：Biochemical and biophysical research communications

authors： Reyes AE,Perez DR,Alvarez A,Garrido J,Gentry MK,Doctor BP,Inestrosa NC

更新日期：1997-03-27 00:00:00

abstract：:The Apical Junctional Complex (AJC) encompassing the tight junction (TJ) and adherens junction (AJ) plays a pivotal role in regulating epithelial barrier function and epithelial cell proliferative processes through signaling events that remain poorly characterized. A potential regulator of AJC protein expression is Gl...

journal_title：Biochemical and biophysical research communications

authors： Severson EA,Kwon M,Hilgarth RS,Parkos CA,Nusrat A

更新日期：2010-07-02 00:00:00

abstract：:The application of Fast Atom Bombardment Mass Spectrometry to the measurement of small differences in molecular weight is discussed in relation to the spectra of bovine proinsulin and a genetic variant. ...

journal_title：Biochemical and biophysical research communications

authors： Cottrell JS,Frank BH

更新日期：1985-03-29 00:00:00

abstract：:Although it is recognized that 4,5-diaminovaleric acid, formed from glutamate 1-semialdehyde, functions as the intermediate in the last step of delta-aminolevulinic acid formation from glutamate, the enantioselectivity of the participating glutamate 1-semialdehyde aminotransferase for 4,5-diaminovaleric acid has remai...

journal_title：Biochemical and biophysical research communications

authors： Friedmann HC,Duban ME,Valasinas A,Frydman B

更新日期：1992-05-29 00:00:00

abstract：:The peroxidase and FAD-containing monooxygenase activities of porcine thyroid subcellular preparations were measured and it was observed that FAD-containing monooxygenase activity was considerably lower than that of peroxidase. The end product of 1-methyl-2[14C]thioimidazole oxidation catalysed by thyroid peroxidase w...

journal_title：Biochemical and biophysical research communications

authors： Paterson JR,Hood HT,Skellern GG

更新日期：1983-10-31 00:00:00

abstract：:Familial ATTR amyloidosis is caused by point mutations in the transthyretin gene. The clinical manifestations are highly varied but polyneuropathy and/or cardiomyopathy are generally the main symptoms. The amyloid fibrils can either be composed of only intact ATTR molecules or intact together with fragmented ATTR spec...

journal_title：Biochemical and biophysical research communications

authors： Ihse E,Stangou AJ,Heaton ND,O'Grady J,Ybo A,Hellman U,Edvinsson A,Westermark P

更新日期：2009-02-20 00:00:00

abstract：:EAG1 channels belong to the KCNH family of voltage gated potassium channels. They are expressed in several brain regions and increased expression is linked to certain cancer types. Recent cryo-EM structure determination finally revealed the structure of these channels in atomic detail, allowing computational investiga...

journal_title：Biochemical and biophysical research communications

authors： Bernsteiner H,Bründl M,Stary-Weinzinger A

更新日期：2017-02-26 00:00:00

abstract：:Arginine decarboxylase (ADC) catalyzes the first step of polyamine (PA) biosynthesis to produce putrescine (Put) from arginine (Arg). One of the 2 Arabidopsis ADC genes, AtADC2, is induced in response to salt stress causing the accumulation of free Put. To analyze the roles of stress-inducible AtADC2 gene and endogeno...

journal_title：Biochemical and biophysical research communications

authors： Urano K,Yoshiba Y,Nanjo T,Ito T,Yamaguchi-Shinozaki K,Shinozaki K

更新日期：2004-01-09 00:00:00

abstract：:The neuropeptide Y (NPY) system is known as one of the major neural signaling pathways. NPY, produced by peripheral tissues including osteoblasts, is known to bind to the Y1 receptor. Recently, osteoblast-specific Y1 receptor knockout mice were developed and were found to have a high bone mass phenotype, indicating a ...

journal_title：Biochemical and biophysical research communications

authors： Kurebayashi N,Sato M,Fujisawa T,Fukushima K,Tamura M

更新日期：2013-10-04 00:00:00

abstract：:Histone acetyltransferase MOF is involved in active transcription regulation through histone H4K16 acetylation. MOF is downexpressed in a number of human tumors, but biological function of MOF in endometrial cancer has not been fully defined. The estrogen receptor α (ERα) is a transcription factor that regulates estro...

journal_title：Biochemical and biophysical research communications

authors： Wu Y,Zeng K,Wang C,Wang S,Sun H,Liu W,Wang X,Niu J,Cong SY,Zhou X,Zhao Y

更新日期：2019-02-05 00:00:00

abstract：:microRNA-222 (miR-222) has been shown to initiate the activation of hepatic stellate cells, which plays an important role in the pathogenesis of liver fibrosis. The aim of our study was to evaluate the role of miR-22 in a mouse model of biliary atresia (BA) induced by Rhesus Rotavirus (RRV) infection. New-born Balb/c ...

journal_title：Biochemical and biophysical research communications

authors： Shen WJ,Dong R,Chen G,Zheng S

更新日期：2014-03-28 00:00:00

abstract：:Burkitt lymphoma cells and their counterpart of normal origin contain proteins with associated tyrosine protein, kinase activity. These proteins were isolated by affinity chromatography and Fast Pressure Liquid Chromatography. Proteins with enzyme activity had an app. M. W. of 47 KDa. This protein in extracts of Burki...

journal_title：Biochemical and biophysical research communications

authors： Semmel M,Biquard JM,Pavloff N,Hanania N,Gay F

更新日期：1989-09-15 00:00:00

abstract：:The rat adult liver and hepatocyte lines express an 1.7-kb variant alpha-fetoprotein (AFP) mRNA which differs from the 2.2-kb fetal AFP transcript in sequence in the 5' region. Here we report the characterization of a variant AFP cDNA, ARFP9, which is 1349 bp in length and encodes a 325 amino acid polypeptide. Nucleot...

journal_title：Biochemical and biophysical research communications

authors： Watanabe T,Jimenez-Molina JL,Chou JY

更新日期：1992-06-15 00:00:00

abstract：:We designed an experimental approach to differentiate the kinetics of protein binding to a lipid membrane from the kinetics of the associated conformational change in the protein. We measured the fluorescence intensity of the single Trp6 in chicken liver bile acid-binding protein (L-BABP) as a function of time after m...

journal_title：Biochemical and biophysical research communications

authors： Galassi V,Nolan V,Villarreal MA,Perduca M,Monaco HL,Montich GG

更新日期：2009-05-15 00:00:00

abstract：:Dexamethasone produced an increased activity of stearoyl-CoA desaturase through the enhancement of delta 9-terminal component activity, and a corresponding decrease of oleoyl-CoA desaturase activity via the reduced activity of delta 12-terminal component in Tetrahymena microsomes. However, the content of cytochrome b5...

journal_title：Biochemical and biophysical research communications

authors： Umeki S,Nozawa Y

更新日期：1984-02-29 00:00:00

abstract：:Using a novel method consisting of chromatin fractionation and allele-specific detection, chromatin packaging is compared between active X (Xa) and inactive X (Xi) chromosomes for five tumor cell clones that were derived from inter-subspecific F1 female mice. Separation of heterochromatic (H) and euchromatic (E) fract...

journal_title：Biochemical and biophysical research communications

authors： Endo Y,Watanabe T,Kuwabara K,Tsunashima K,Mishima Y,Arakawa M,Takagi N,Kominami R

更新日期：1998-03-06 00:00:00

abstract：:Activating transcription factor 3 (ATF3) is an immediate early response gene that is induced in cells exposed to a variety of stress stimuli. In this report, upon exposure of cells to ultraviolet (UV) or proteasome inhibitor MG132, ATF3 protein was induced more efficiently in cells with intact p53 allele than in those...

journal_title：Biochemical and biophysical research communications

authors： Zhang C,Gao C,Kawauchi J,Hashimoto Y,Tsuchida N,Kitajima S

更新日期：2002-10-11 00:00:00

abstract：:A method has been developed for the specific amplification and cloning of human hprt cDNA which can be used for mutant sequence analysis. Messenger RNA is isolated from TK6 lymphoblasts and is used to produce a first strand cDNA with reverse transcriptase primed with oligo dT. Second strand synthesis and subsequent am...

journal_title：Biochemical and biophysical research communications

authors： Simpson D,Crosby RM,Skopek TR

更新日期：1988-02-29 00:00:00

abstract：:Insulin-like growth factor I stimulates mitogenesis in smooth muscle cells, and upregulates elastin synthesis in embryonic aortic tissue. Increased smooth muscle elastin synthesis may play an important role in vascular remodeling in chronic pulmonary hypertension. Therefore, we studied the effect of IGF-I on elastin a...

journal_title：Biochemical and biophysical research communications

authors： Badesch DB,Lee PD,Parks WC,Stenmark KR

更新日期：1989-04-14 00:00:00

abstract：:The earthworm Lumbricus rubellus has been found to inhabit cadmium-rich soils and accumulate cadmium within its tissues. Two metallothionein (MT) isoforms (1 and 2) have been identified and cloned from L. rubellus. In this study, we address the metalation status, metal coordination, and structure of recombinant MT-2 f...

journal_title：Biochemical and biophysical research communications

authors： Ngu TT,Sturzenbaum SR,Stillman MJ

更新日期：2006-12-08 00:00:00

abstract：:The proton-translocating pyridine nucleotide transhydrogenase of Escherichia coli is composed of two types of subunits, alpha and beta, organized as an alpha(2)beta(2) tetramer. The protein contains three recognizable domains, of which domain II is the transmembrane region of the molecule containing the pathway for pr...

journal_title：Biochemical and biophysical research communications

authors： Hou C,Bragg PD

更新日期：2001-01-19 00:00:00

abstract：:The peroxisome proliferator activated receptors (PPARs) alpha, beta/delta, and gamma are novel nuclear hormone receptors activated by long chain fatty acids and synthetic ligands and which regulate lipid metabolism. Recent studies have detected PPARgamma mRNA in human mammary tumor cell lines. The current study examin...

journal_title：Biochemical and biophysical research communications

authors： Gimble JM,Pighetti GM,Lerner MR,Wu X,Lightfoot SA,Brackett DJ,Darcy K,Hollingsworth AB

更新日期：1998-12-30 00:00:00

abstract：:Potassium homeostasis plays an essential role in the control of blood pressure. It is unknown, however, whether potassium balance is involved in the gender-associated blood pressure differences. We therefore investigated the possible mechanism of sexual dimorphism in blood pressure regulation by measuring the blood pr...

journal_title：Biochemical and biophysical research communications

authors： Yu G,Cheng M,Wang W,Zhao R,Liu Z

更新日期：2017-04-01 00:00:00

abstract：:S-100 protein and annexin II2-p11(2) were reported to inhibit and to stimulate the assembly of glial fibrillary acidic protein (GFAP), respectively, in a Ca(2+)-dependent manner. Here we show by a number of experimental approaches that S-100 protein contrasts all the effects of annexin II2-p11(2) on GFAP assembly and,...

journal_title：Biochemical and biophysical research communications

authors： Bianchi R,Garbuglia M,Verzini M,Giambanco I,Spreca A,Donato R

更新日期：1995-03-28 00:00:00

abstract：:The effect of silkworm hemolymph on baculovirus-induced insect cell apoptosis was investigated. The addition of silkworm hemolymph into the culture medium either before or during the baculovirus infection increased the host cell longevity; however, its addition after the infection was less effective. This can be expla...

journal_title：Biochemical and biophysical research communications

authors： Rhee WJ,Park TH

更新日期：2000-04-29 00:00:00

abstract：:Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset dominant genetic disease caused by the expansion of a GCG trinucleotide repeat that encodes the polyalanine tract at the N-terminus of the nuclear poly(A)-binding protein (PABPN1). Presence of intranuclear inclusions (INIs) containing PABPN1 aggregates in the...

journal_title：Biochemical and biophysical research communications

authors： Wang Q,Bag J

更新日期：2006-02-17 00:00:00