Abstract:
:The nourseothricin-producing S. noursei strain JA 3890b possessed a high degree of resistance to its own antibiotic when grown in submerged cultures started from mycelium samples as inocula. In contrast, both the outgrowth of spores and the development of surface colonies from mycelium samples were severely inhibited in the presence of relatively low concentrations of nourseothricin, suggesting that the producer organism is susceptible to the autotoxic metabolite in particular stages of its development. Nourseothricin production by submerged cultures has been found to be independent of negative feedback regulation by the antibiotic.
journal_name
J Basic Microbioljournal_title
Journal of basic microbiologyauthors
Röder B,Plonka G,Bormann EJ,Gräfe Udoi
10.1002/jobm.3620250306subject
Has Abstractpub_date
1985-01-01 00:00:00pages
175-86issue
3eissn
0233-111Xissn
1521-4028journal_volume
25pub_type
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