Use of Favipiravir to Treat Lassa Virus Infection in Macaques.

Abstract:

:Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus-viremic macaques and found that 300 mg/kg daily for 2 weeks successfully treated infection.

journal_name

Emerg Infect Dis

authors

Rosenke K,Feldmann H,Westover JB,Hanley PW,Martellaro C,Feldmann F,Saturday G,Lovaglio J,Scott DP,Furuta Y,Komeno T,Gowen BB,Safronetz D

doi

10.3201/eid2409.180233

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

1696-1699

issue

9

eissn

1080-6040

issn

1080-6059

journal_volume

24

pub_type

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