Intestinal dysbiosis: novel mechanisms by which gut microbes trigger and prevent disease.

Abstract:

:New research has identified specific intestinal colonizing microbes that can have significant influence on health and disease. Evidence is reviewed supporting an association between Fusobacterium nucleatum and colon cancer and for a protective role of Faecalibacterium prausnitzii in inflammatory bowel disease, of Escherichia coli Nissle 1917 in acute intestinal inflammation, of Bifidobacterium infantis in neonatal necrotizing enterocolitis, and of Akkermansia muciniphila in obesity and diabetes. These novel bacteria are clinically relevant and present opportunities for more focused diagnosis of colon cancer and prevention of common diseases.

journal_name

Prev Med

journal_title

Preventive medicine

authors

Underwood MA

doi

10.1016/j.ypmed.2014.05.010

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

133-7

eissn

0091-7435

issn

1096-0260

pii

S0091-7435(14)00176-5

journal_volume

65

pub_type

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